Gene: Slc22a1 (solute carrier family 22 member 1) Rattus norvegicus
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Symbol: Slc22a1
Name: solute carrier family 22 member 1
Description: ENCODES a protein that exhibits acetylcholine transmembrane transporter activity; dopamine transmembrane transporter activity; identical protein binding; INVOLVED IN dopamine transport; drug transmembrane transport; epinephrine transport; PARTICIPATES IN lamivudine pharmacokinetics pathway; metformin pharmacokinetics pathway; tramadol pharmacokinetics pathway; ASSOCIATED WITH acute kidney failure; Acute Kidney Injury; Asthma; FOUND IN basolateral plasma membrane; integral component of plasma membrane; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3-chloropropane-1,2-diol
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: MGC93570; Oct1; Orct1; organic cation transporter; organic cation transporter 1; Roct1; solute carrier family 22 (organic cation transporter), member 1; solute carrier family 22, member 1
Orthologs:
Homo sapiens (human) : SLC22A1 (solute carrier family 22 member 1)  HGNC  AGR
Mus musculus (house mouse) : Slc22a1 (solute carrier family 22 (organic cation transporter), member 1)  MGI  AGR
Pan paniscus (bonobo/pygmy chimpanzee) : SLC22A1 (solute carrier family 22 member 1)
Canis lupus familiaris (dog) : SLC22A1 (solute carrier family 22 member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Slc22a1 (solute carrier family 22 member 1)
more info ...
Allele / Splice: Slc22a1em1Sage  
Genetic Models: SD-Slc22a1em1Sage
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0148,273,639 - 48,300,645 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0151,452,604 - 51,479,610 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4142,351,239 - 42,378,295 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1142,354,183 - 42,381,239 (+)NCBI
Celera143,876,335 - 43,903,290 (+)NCBI
Cytogenetic Map1q11NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Slc22a1
AGR Gene
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 3224
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-10-03
Status: ACTIVE