Mpz (myelin protein zero) - Rat Genome Database

Name: Mpz
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Mpz (myelin protein zero) Rattus norvegicus

Analyze

Symbol:

Mpz

Name:

myelin protein zero

RGD ID:

3109

Description:

Involved in negative regulation of apoptotic process. Located in basolateral plasma membrane. Biomarker of diabetic neuropathy and sciatic neuropathy. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease (multiple). Orthologous to human MPZ (myelin protein zero); INTERACTS WITH (20S)-20-hydroxypregn-4-en-3-one; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

REVIEWED

Previously known as:

MPP; myelin peripheral protein; myelin protein P0; Myelin protein zero (Charcot-Marie-Tooth neuropathy 1B); P0

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MPZ (myelin protein zero)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Mpz (myelin protein zero)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Mpz (myelin protein zero)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MPZ (myelin protein zero)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MPZ (myelin protein zero)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Mpz (myelin protein zero)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MPZ (myelin protein zero)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MPZ (myelin protein zero)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Mpz (myelin protein zero)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	TNNI1 (troponin I1, slow skeletal type)	HGNC	OMA
Alliance orthologs ³
Mus musculus (house mouse):	Mpz (myelin protein zero)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	MPZ (myelin protein zero)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	mpz (myelin protein zero)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	mpz	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	86,103,290 - 86,109,156 (+)	NCBI		GRCr8
mRatBN7.2	13	83,570,811 - 83,576,680 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	83,570,811 - 83,576,679 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	86,076,519 - 86,082,418 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	87,474,755 - 87,480,657 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	84,706,501 - 84,712,211 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	89,524,204 - 89,530,070 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	89,524,329 - 89,530,068 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	94,151,850 - 94,156,749 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	87,040,479 - 87,045,378 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	87,229,362 - 87,234,262 (+)	NCBI
Celera	13	83,202,202 - 83,207,991 (+)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atrophic muscular disease (ISO)

autoimmune interstitial lung, joint, and kidney disease (ISO)

autosomal dominant distal hereditary motor neuronopathy 14 (ISO)

autosomal dominant distal hereditary motor neuronopathy 2 (ISO)

Carney-Stratakis syndrome (ISO)

Charcot-Marie-Tooth disease (ISO)

Charcot-Marie-Tooth disease dominant intermediate D (ISO)

Charcot-Marie-Tooth disease intermediate type (ISO)

Charcot-Marie-Tooth disease type 1 (ISO)

Charcot-Marie-Tooth disease type 1B (ISO,ISS)

Charcot-Marie-Tooth disease type 2I (ISO)

Charcot-Marie-Tooth disease type 2J (ISO)

Charcot-Marie-Tooth disease type 3 (ISO,ISS)

Charcot-Marie-Tooth disease type 4E (ISO)

Charcot-Marie-Tooth Disease, Dominant Intermediate 3 (ISO)

Congenital Hypomyelinating Neuropathy 2 (ISO)

diabetic neuropathy (IEP)

distal myopathy (ISO)

gastrointestinal stromal tumor (ISO)

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Hereditary Paraganglioma-Pheochromocytoma Syndromes (ISO)

Hyperalgesia (ISO)

intellectual disability (ISO)

Islet Cell Tumor Syndrome (ISO)

motor neuron disease (ISO)

motor peripheral neuropathy (ISO)

Nerve Degeneration (ISO)

neuropathy (ISO,ISS)

paraganglioma (ISO)

Paragangliomas 3 (ISO)

parathyroid carcinoma (ISO)

PCWH syndrome (ISS)

peripheral nervous system disease (ISO)

pheochromocytoma (ISO)

primary cerebellar degeneration (ISO)

sciatic neuropathy (IEP)

sensory peripheral neuropathy (ISO)

Talipes Cavus (ISO)

Tremor (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(20S)-20-hydroxypregn-4-en-3-one (EXP)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3alpha-hydroxy-5beta-pregnan-20-one (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

5-aminolevulinic acid (EXP)

all-trans-retinoic acid (ISO)

ammonium chloride (EXP)

arsenous acid (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bortezomib (EXP,ISO)

cadmium dichloride (EXP)

carbamazepine (ISO)

chlorpyrifos (EXP)

cisplatin (ISO)

diarsenic trioxide (ISO)

diazinon (EXP)

dicrotophos (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

glycidol (EXP)

iron dichloride (ISO)

linalool (EXP)

lipopolysaccharide (ISO)

lithium chloride (ISO)

N-Nitrosopyrrolidine (ISO)

nickel atom (ISO)

nitrofen (EXP)

panobinostat (ISO)

paracetamol (ISO)

paraquat (ISO)

perfluorooctanoic acid (ISO)

progesterone (EXP)

quercetin (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

sirolimus (ISO)

sodium arsenite (EXP,ISO)

streptozocin (EXP)

sunitinib (ISO)

testosterone (EXP)

thapsigargin (EXP)

trichloroethene (EXP)

trichostatin A (ISO)

valproic acid (ISO)

vincristine (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell aggregation (IEA,ISO,ISS)

cell-cell adhesion via plasma-membrane adhesion molecules (IEA,ISO,ISS)

cell-cell junction maintenance (ISO)

myelination (IBA,IEA,ISO,ISS)

negative regulation of apoptotic process (IMP)

Cellular Component

basolateral plasma membrane (IDA)

plasma membrane (IBA,IEA,IMP,ISO)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Two amino-acid substitutions in the myelin protein zero gene of a case of Charcot-Marie-Tooth disease associated with light-near dissociation.	Bienfait HM, etal., Neuromuscul Disord 2002 Mar;12(3):281-5.
2.	Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: protective effects of LXR activation.	Cermenati G, etal., J Lipid Res. 2012 Feb;53(2):300-10. doi: 10.1194/jlr.M021188. Epub 2011 Dec 7.
3.	Cultured Schwann cells constitutively express the myelin protein P0.	Cheng L and Mudge AW, Neuron. 1996 Feb;16(2):309-19.
4.	Peripheral myelin protein 22 and protein zero: a novel association in peripheral nervous system myelin.	D'Urso D, etal., J Neurosci. 1999 May 1;19(9):3396-403.
5.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
7.	A dual tyrosine-leucine motif mediates myelin protein P0 targeting in MDCK cells.	Kidd GJ, etal., Glia. 2006 Aug 1;54(2):135-45.
8.	Mpz gene suppression by shRNA increases Schwann cell apoptosis in vitro.	Lei L, etal., Neurol Sci. 2010 Oct;31(5):603-8. doi: 10.1007/s10072-010-0341-2. Epub 2010 Jun 15.
9.	Isolation and sequence of a cDNA encoding the major structural protein of peripheral myelin.	Lemke G and Axel R, Cell 1985 Mar;40(3):501-8.
10.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
11.	An axonal form of Charcot-Marie-Tooth disease showing distinctive features in association with mutations in the peripheral myelin protein zero gene (Thr124Met or Asp75Val).	Misu K, etal., J Neurol Neurosurg Psychiatry 2000 Dec;69(6):806-11.
12.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
13.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
14.	GOA pipeline	RGD automated data pipeline
15.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
17.	Comprehensive gene review and curation	RGD comprehensive gene curation
18.	Electrical stimulation enhances peripheral nerve regeneration after crush injury in rats.	Zhang X, etal., Mol Med Rep. 2013 May;7(5):1523-7. doi: 10.3892/mmr.2013.1395. Epub 2013 Mar 26.

Additional References at PubMed

PMID:1690568	PMID:2483091	PMID:8816707	PMID:10545037	PMID:11726686	PMID:11749037	PMID:12477932	PMID:15207917	PMID:15456935	PMID:15580626	PMID:16493674	PMID:17325040
PMID:18337304	PMID:20568451	PMID:20731761	PMID:21179557	PMID:22457349	PMID:22564491	PMID:29081003	PMID:31059078

Genomics

Comparative Map Data

Mpz
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	13	86,103,290 - 86,109,156 (+)	NCBI		GRCr8
mRatBN7.2	13	83,570,811 - 83,576,680 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	13	83,570,811 - 83,576,679 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	13	86,076,519 - 86,082,418 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	13	87,474,755 - 87,480,657 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	13	84,706,501 - 84,712,211 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	13	89,524,204 - 89,530,070 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	13	89,524,329 - 89,530,068 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	13	94,151,850 - 94,156,749 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	87,040,479 - 87,045,378 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	13	87,229,362 - 87,234,262 (+)	NCBI
Celera	13	83,202,202 - 83,207,991 (+)	NCBI		Celera
Cytogenetic Map	13	q24	NCBI

MPZ
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	161,303,600 - 161,309,968 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	161,304,735 - 161,309,968 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	161,274,525 - 161,279,758 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	159,541,151 - 159,546,377 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	158,087,599 - 158,092,817	NCBI
Celera	1	134,341,666 - 134,346,903 (-)	NCBI		Celera
Cytogenetic Map	1	q23.3	NCBI
HuRef	1	132,631,395 - 132,636,601 (-)	NCBI		HuRef
CHM1_1	1	162,670,753 - 162,675,990 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	160,441,004 - 160,447,413 (-)	NCBI		T2T-CHM13v2.0

Mpz
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	170,978,282 - 170,988,699 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	1	170,978,280 - 170,988,699 (+)	Ensembl		GRCm39 Ensembl
GRCm38	1	171,150,713 - 171,161,130 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	171,150,711 - 171,161,130 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	173,080,844 - 173,091,254 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	1	172,987,388 - 172,997,798 (+)	NCBI		MGSCv36	mm8
Celera	1	173,598,959 - 173,609,357 (+)	NCBI		Celera
Cytogenetic Map	1	H3	NCBI
cM Map	1	79.05	NCBI

Mpz
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955468	13,041,011 - 13,047,284 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955468	13,041,911 - 13,047,026 (-)	NCBI	ChiLan1.0	ChiLan1.0

MPZ
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	88,543,449 - 88,573,944 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	88,233,764 - 88,264,228 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	136,691,245 - 136,720,958 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	140,603,609 - 140,631,273 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	140,626,039 - 140,631,273 (-)	Ensembl	panpan1.1		panPan2

MPZ
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	38	21,205,339 - 21,210,439 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	38	21,205,107 - 21,210,451 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	38	21,280,251 - 21,285,323 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	38	21,323,207 - 21,328,277 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	38	21,323,098 - 21,328,270 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	38	21,220,355 - 21,225,416 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	38	21,626,466 - 21,631,518 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	38	22,034,738 - 22,039,792 (+)	NCBI		UU_Cfam_GSD_1.0

Mpz
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	7,375,284 - 7,380,521 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936903	583,942 - 589,160 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936903	583,942 - 589,160 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MPZ
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	89,169,311 - 89,179,925 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	89,174,107 - 89,179,556 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	97,031,478 - 97,036,934 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MPZ
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	2,662,163 - 2,668,393 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	2,665,737 - 2,668,393 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	1,720,210 - 1,725,435 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mpz
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624794	100,824 - 106,444 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624794	101,095 - 106,508 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mpz
28 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	110
Count of miRNA genes:	90
Interacting mature miRNAs:	101
Transcripts:	ENSRNOT00000004279
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	101056920	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	101056920	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	8897350	101631289	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	20605871	101339738	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	30395351	101056920	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	31241331	93395974	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	31241331	93395974	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39754544	84754544	Rat
12879444	Bp397	Blood pressure QTL 397			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45049404	90049404	Rat
12879471	Bp398	Blood pressure QTL 398			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45514719	90514719	Rat
12879441	Bp396	Blood pressure QTL 396			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	45699983	90699983	Rat
1298066	Bp159	Blood pressure QTL 159		0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	46088046	91088046	Rat
71119	Thym2	Thymus enlargement QTL 2	3.8		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	13	46197976	84753113	Rat
1641901	Alcrsp6	Alcohol response QTL 6			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	13	52362171	97362171	Rat
1354655	Bp241	Blood pressure QTL 241	3.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	56056920	101056920	Rat
738026	Lnnr5	Liver neoplastic nodule remodeling QTL 5	3.29		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	59874408	85581182	Rat
12879475	Bp400	Blood pressure QTL 400			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	61825626	106807694	Rat
2293702	Bss34	Bone structure and strength QTL 34	4.61	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	13	65103704	106807694	Rat
2293687	Bss26	Bone structure and strength QTL 26	4.6	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	13	65103704	106807694	Rat
8655945	Rf61	Renal function QTL 61	3.6		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	13	69060519	86800898	Rat
1331783	Bp221	Blood pressure QTL 221	3.72886		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	69060519	86800898	Rat
1300166	Kidm6	Kidney mass QTL 6	3.93		kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	13	69060519	86800898	Rat
8655959	Pur32	Proteinuria QTL 32	8.4		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	74023918	97213863	Rat
738027	Lnnr6	Liver neoplastic nodule remodeling QTL 6	3.3		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	74862117	85581182	Rat
2293341	Glom15	Glomerulus QTL 15	9.1		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	13	74862117	101339893	Rat
4889606	Gluco63	Glucose level QTL 63	2.86	0.003	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	13	80753256	106807694	Rat

Markers in Region

RH129131

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	83,576,485 - 83,576,647 (+)	MAPPER	mRatBN7.2
Rnor_6.0	13	89,529,876 - 89,530,037	NCBI	Rnor6.0
Rnor_5.0	13	94,157,377 - 94,157,538	UniSTS	Rnor5.0
RGSC_v3.4	13	87,046,006 - 87,046,167	UniSTS	RGSC3.4
Celera	13	83,207,797 - 83,207,958	UniSTS
RH 3.4 Map	13	561.7	UniSTS
Cytogenetic Map	13	q24-q25	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2		1		1		6	8	11		6	6	6
Low		23	18	3	18	3	2	3	39	6	26	5	2
Below cutoff	1	20	15	15		15			20	28	9

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001314068	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_017027	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB197140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC099236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC078859	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB608173	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473985	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000013	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	K03242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000004279 ⟹ ENSRNOP00000004279

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	83,570,811 - 83,576,679 (+)	Ensembl
Rnor_6.0 Ensembl	13	89,524,329 - 89,530,068 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000109813 ⟹ ENSRNOP00000095879

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	13	83,573,143 - 83,576,679 (+)	Ensembl

RefSeq Acc Id:

NM_001314068 ⟹ NP_001300997

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	86,103,290 - 86,109,156 (+)	NCBI
mRatBN7.2	13	83,570,811 - 83,576,680 (+)	NCBI
Rnor_6.0	13	89,524,204 - 89,530,070 (+)	NCBI
Celera	13	83,202,202 - 83,207,991 (+)	NCBI

Sequence:

show sequence

CCACCTCTCAATTGCACATGCCAGGCTGCAATTGGTCACTGGCTCAGGACAGCCCCCTCATGCT
GGGGATCCAGGGGATTTTAAGCAGGTTCCAGAAAACACCACTCAGTTCCTTGTCCCCCGCTCTC
TCCACCCCACAGACGCTCTGGGCCCTTGCCCCTACCCCAGCTATGGCTCCTGGGGCTCCCTCAT
CCAGCCCCAGCCCTATCCTGGCTGCCCTGCTCTTCTCTTCTTTGGTGCTGTCCCCAACCCTGGC
CATTGTGGTTTACACGGACAGGGAAGTCTATGGTGCTGTGGGCTCCCAGGTGACCCTGCACTGC
TCCTTCTGGTCCAGTGAATGGGTCTCAGATGACATCTCTTTTACCTGGCGCTACCAGCCTGAAG
GAGGCCGAGATGCCATTTCAATCTTCCACTATGCCAAGGGTCAACCTTACATCGATGAGGTGGG
GACCTTCAAGGAGCGCATCCAGTGGGTAGGGGACCCTAGCTGGAAGGATGGCTCCATTGTCATA
CACAACCTAGACTACAGTGACAACGGCACTTTCACATGTGATGTCAAAAACCCACCGGACATAG
TGGGCAAGACGTCTCAGGTCACGCTCTATGTCTTTGAAAAAGTGCCCACTAGGTATGGGGTGGT
GTTGGGAGCCGTGATCGGTGGCATCCTCGGGGTGGTGCTGTTGCTGCTGTTGCTCTTCTACCTG
ATCCGGTACTGCTGGCTGCGCAGGCAGGCTGCCCTGCAGAGGAGGCTCAGTGCCATGGAGAAGG
GGAAATTTCACAAGTCTTCTAAGGACTCCTCGAAGCGCGGGCGGCAGACGCCAGTGCTGTATGC
CATGCTGGACCACAGCCGAAGCACCAAAGCTGCCAGTGAGAAGAAATCTAAAGGGCTGGGGGAG
TCTCGCAAGGATAAGAAATAGCGGTTAGCGGGCCGGGCGGGGGGTCGGGGGTCTGCGATGGAGT
CTTCCAAAGGCTCTCAGGTGGTGGTCATCGAGATGGAGCTTCGCAAAGATGAGCAGAGCTCGGA
GCTCCGGCCTGCAGTCAAATCCCCCAGTAGAACCAGCCTCAAGAACGCCCTCAAGAACATGATG
GGCCTGGACTCGGACAAGTGACCGTCACCTCCAGGCTCTGTCAGAGCAGGGGACCTAGGCTCCT
CTTTTTCCCAGGTCTAGATGCTTTCCCCTTGCTCCTCAGCCCTGCCCTGCCCTTACCTCCCAAT
GAGATGTAAAGTTTCATTCCAATGTTCCTTCCCAAGTCTTGTATTTCTCCTTCACTTTTTCCCC
TCGGCTTTCCGGGAGCCTAGGGACTAACTCTACTCCTCACCTGCCCCAAGGGCTGTGTGTTTGG
TGCCTCTCCCTCAGGCACCGAGAAGAAAGGAACCTTGATAGCCTCTGCCCAACTCCAGGCCACT
GGGCCTTCCCATCTCCTCCTCCGGTTCCCCTGGCTCCTTCCTGCTGTCTCCTTTCCTACCTTGT
GGTGGCCCAGCTCCACACTCTGTCCTCGGGCTCAAATCCACATCATGCAGATCAGACTCTCCAT
CAGGGTTTATCTAGGTTGCTGAGTATTTTTTATTTGTTCATCCATCCTTTGTTTACCTGAGCCC
ACGGCCCCATGACCGAGGACCAATGACGTCATGTGGCTTTTGCAGTTCCCCACTCCTATTAAGT
CTTTACTGGAGAGCCAGCCAGGCAAGCAGAGCATAATTGAGGCCCTCTGACTGACCACTCTGGA
GCACAGTTCTGAGACTCCGAGATTTGGGGAAGGAGAGAGAGAAAAAATGGATCTTCACAGGTCA
GGGGTGCAGTAGGGAGCTTCAAGAAACGTCTTCGAAATAAGTAATAAGGAGAACAGGGAAAGCC
AATGAGAATAGGAAGGAAAGGAAGTGGTTGCACTCCCAGGCACAGGGGACTGTTAGGACTTTTC
TACATTCTGTATATTTCTCCTACCATCTCCAAATGTCCTTAAATGTTTAATAAACACTGACATT
TCCAGGAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_017027 ⟹ NP_058723

RefSeq Status:

REVIEWED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	13	86,103,290 - 86,109,156 (+)	NCBI
mRatBN7.2	13	83,570,811 - 83,576,680 (+)	NCBI
Rnor_6.0	13	89,524,204 - 89,530,070 (+)	NCBI
Rnor_5.0	13	94,151,850 - 94,156,749 (+)	NCBI
RGSC_v3.4	13	87,040,479 - 87,045,378 (+)	RGD
Celera	13	83,202,202 - 83,207,991 (+)	NCBI

Sequence:

show sequence

CCACCTCTCAATTGCACATGCCAGGCTGCAATTGGTCACTGGCTCAGGACAGCCCCCTCATGCT
GGGGATCCAGGGGATTTTAAGCAGGTTCCAGAAAACACCACTCAGTTCCTTGTCCCCCGCTCTC
TCCACCCCACAGACGCTCTGGGCCCTTGCCCCTACCCCAGCTATGGCTCCTGGGGCTCCCTCAT
CCAGCCCCAGCCCTATCCTGGCTGCCCTGCTCTTCTCTTCTTTGGTGCTGTCCCCAACCCTGGC
CATTGTGGTTTACACGGACAGGGAAGTCTATGGTGCTGTGGGCTCCCAGGTGACCCTGCACTGC
TCCTTCTGGTCCAGTGAATGGGTCTCAGATGACATCTCTTTTACCTGGCGCTACCAGCCTGAAG
GAGGCCGAGATGCCATTTCAATCTTCCACTATGCCAAGGGTCAACCTTACATCGATGAGGTGGG
GACCTTCAAGGAGCGCATCCAGTGGGTAGGGGACCCTAGCTGGAAGGATGGCTCCATTGTCATA
CACAACCTAGACTACAGTGACAACGGCACTTTCACATGTGATGTCAAAAACCCACCGGACATAG
TGGGCAAGACGTCTCAGGTCACGCTCTATGTCTTTGAAAAAGTGCCCACTAGGTATGGGGTGGT
GTTGGGAGCCGTGATCGGTGGCATCCTCGGGGTGGTGCTGTTGCTGCTGTTGCTCTTCTACCTG
ATCCGGTACTGCTGGCTGCGCAGGCAGGCTGCCCTGCAGAGGAGGCTCAGTGCCATGGAGAAGG
GGAAATTTCACAAGTCTTCTAAGGACTCCTCGAAGCGCGGGCGGCAGACGCCAGTGCTGTATGC
CATGCTGGACCACAGCCGAAGCACCAAAGCTGCCAGTGAGAAGAAATCTAAAGGGCTGGGGGAG
TCTCGCAAGGATAAGAAATAGCGGTTAGCGGGCCGGGCGGGGGGTCGGGGGTCTGCGATGGAGT
CTTCCAAAGGCTCTCAGGTGGTGGTCATCGAGATGGAGCTTCGCAAAGATGAGCAGAGCTCGGA
GCTCCGGCCTGCAGTCAAATCCCCCAGTAGAACCAGCCTCAAGAACGCCCTCAAGAACATGATG
GGCCTGGACTCGGACAAGTGACCGTCACCTCCAGGCTCTGTCAGAGCAGGGGACCTAGGCTCCT
CTTTTTCCCAGGTCTAGATGCTTTCCCCTTGCTCCTCAGCCCTGCCCTGCCCTTACCTCCCAAT
GAGATGTAAAGTTTCATTCCAATGTTCCTTCCCAAGTCTTGTATTTCTCCTTCACTTTTTCCCC
TCGGCTTTCCGGGAGCCTAGGGACTAACTCTACTCCTCACCTGCCCCAAGGGCTGTGTGTTTGG
TGCCTCTCCCTCAGGCACCGAGAAGAAAGGAACCTTGATAGCCTCTGCCCAACTCCAGGCCACT
GGGCCTTCCCATCTCCTCCTCCGGTTCCCCTGGCTCCTTCCTGCTGTCTCCTTTCCTACCTTGT
GGTGGCCCAGCTCCACACTCTGTCCTCGGGCTCAAATCCACATCATGCAGATCAGACTCTCCAT
CAGGGTTTATCTAGGTTGCTGAGTATTTTTTATTTGTTCATCCATCCTTTGTTTACCTGAGCCC
ACGGCCCCATGACCGAGGACCAATGACGTCATGTGGCTTTTGCAGTTCCCCACTCCTATTAAGT
CTTTACTGGAGAGCCAGCCAGGCAAGCAGAGCATAATTGAGGCCCTCTGACTGACCACTCTGGA
GCACAGTTCTGAGACTCCGAGATTTGGGGAAGGAGAGAGAGAAAAAATGGATCTTCACAGGTCA
GGGGTGCAGTAGGGAGCTTCAAGAAACGTCTTCGAAATAAGTAATAAGGAGAACAGGGAAAGCC
AATGAGAATAGGAAGGAAAGGAAGTGGTTGCACTCCCAGGCACAGGGGACTGTTAGGACTTTTC
TACATTCTGTATATTTCTCCTACCATCTCCAAATGTCCTTAAATGTTTAATAAACACTGACATT
TCCAGGAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001300997	(Get FASTA)	NCBI Sequence Viewer
	NP_058723	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA41576	(Get FASTA)	NCBI Sequence Viewer
	BAD83366	(Get FASTA)	NCBI Sequence Viewer
	EDL94598	(Get FASTA)	NCBI Sequence Viewer
	EDL94599	(Get FASTA)	NCBI Sequence Viewer
	EDL94600	(Get FASTA)	NCBI Sequence Viewer
	EDL94601	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000004279
	ENSRNOP00000004279.4
	ENSRNOP00000095879.1
GenBank Protein	P06907	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_058723 ⟸ NM_017027
- Peptide Label:	isoform MPZ precursor
- UniProtKB:	P06907 (UniProtKB/Swiss-Prot), A6JFU2 (UniProtKB/TrEMBL), A0A8I6GLD0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAPGAPSSSPSPILAALLFSSLVLSPTLAIVVYTDREVYGAVGSQVTLHCSFWSSEWVSDDISF TWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPSWKDGSIVIHNLDYSDNGTFTCD VKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGILGVVLLLLLLFYLIRYCWLRRQAALQR RLSAMEKGKFHKSSKDSSKRGRQTPVLYAMLDHSRSTKAASEKKSKGLGESRKDKK hide sequence

RefSeq Acc Id:

NP_001300997 ⟸ NM_001314068

- Peptide Label:

isoform L-MPZ precursor

- Sequence:

show sequence

MAPGAPSSSPSPILAALLFSSLVLSPTLAIVVYTDREVYGAVGSQVTLHCSFWSSEWVSDDISF
TWRYQPEGGRDAISIFHYAKGQPYIDEVGTFKERIQWVGDPSWKDGSIVIHNLDYSDNGTFTCD
VKNPPDIVGKTSQVTLYVFEKVPTRYGVVLGAVIGGILGVVLLLLLLFYLIRYCWLRRQAALQR
RLSAMEKGKFHKSSKDSSKRGRQTPVLYAMLDHSRSTKAASEKKSKGLGESRKDKKXRLAGRAG
GRGSAMESSKGSQVVVIEMELRKDEQSSELRPAVKSPSRTSLKNALKNMMGLDSDK

hide sequence

RefSeq Acc Id:

ENSRNOP00000004279 ⟸ ENSRNOT00000004279

RefSeq Acc Id:

ENSRNOP00000095879 ⟸ ENSRNOT00000109813

Protein Domains

Ig-like Ig-like V-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P06907-F1-model_v2	AlphaFold	P06907	1-248	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698996

Promoter ID:

EPDNEW_R9519

Type:

single initiation site

Name:

Mpz_1

Description:

myelin protein zero

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	89,524,311 - 89,524,371	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:3109	AgrOrtholog
BioCyc Gene	G2FUF-17387	BioCyc
Ensembl Genes	ENSRNOG00000003171	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000004279	ENTREZGENE
	ENSRNOT00000004279.6	UniProtKB/TrEMBL
	ENSRNOT00000109813.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7121950	IMAGE-MGC_LOAD
InterPro	Ig-like_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_sub	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig_V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Myelin-PO_C	UniProtKB/Swiss-Prot
	Myelin_P0-rel	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Myelin_P0_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Myelin_P0_Ig-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MYP0_C	UniProtKB/TrEMBL
KEGG Report	rno:24564	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:93520	IMAGE-MGC_LOAD
NCBI Gene	24564	ENTREZGENE
PANTHER	PTHR13869	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR13869:SF7	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Myelin-PO_C	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	V-set	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mpz	PhenoGen
PRINTS	MYELINP0	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	IG_LIKE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	MYELIN_P0	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000003171	RatGTEx
SMART	IGv	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SM00409	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF48726	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6GLD0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2Q1P3_RAT	UniProtKB/TrEMBL
	A6JFU2	ENTREZGENE, UniProtKB/TrEMBL
	A6JFU4_RAT	UniProtKB/TrEMBL
	A6JFU5_RAT	UniProtKB/TrEMBL
	MYP0_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Mpz	Myelin protein zero (Charcot-Marie-Tooth neuropathy 1B)			Symbol and Name status set to approved	70586	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_process	may be involved in organizing formation of the myelin sheath	728953

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

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