Mep1a (meprin A subunit alpha) - Rat Genome Database

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Gene: Mep1a (meprin A subunit alpha) Rattus norvegicus
Analyze
Symbol: Mep1a
Name: meprin A subunit alpha
RGD ID: 3080
Description: Predicted to enable metallodipeptidase activity and metalloendopeptidase activity. Predicted to be involved in epidermal growth factor receptor ligand maturation. Part of meprin A complex. Orthologous to human MEP1A (meprin A subunit alpha); INTERACTS WITH ammonium chloride; copper atom; copper(0).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: E-24.18; endopeptidase-2; endopeptidase-24.18 subunit alpha; LOC688307; MEP-1; meprin 1 alpha; meprin 1 subunit alpha; meprin A alpha; similar to Meprin A alpha-subunit precursor (Endopeptidase-2) (MEP-1) (Endopeptidase-24.18 alpha-subunit) (E-24.18)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,971,901 - 25,001,414 (+)NCBIGRCr8
mRatBN7.2917,474,634 - 17,504,147 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl917,474,619 - 17,504,147 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx926,065,182 - 26,095,281 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0931,139,752 - 31,169,851 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0929,428,977 - 29,459,076 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0920,048,163 - 20,077,678 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,048,121 - 20,077,702 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,925,181 - 18,953,891 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,170,762 - 13,201,094 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1913,168,083 - 13,198,416 (+)NCBI
Celera915,197,113 - 15,224,494 (+)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA,ISO)
meprin A complex  (IDA,ISO)
plasma membrane  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Probing the active sites and mechanisms of rat metalloproteases meprin A and B. Bertenshaw GP, etal., Biol Chem 2002 Jul-Aug;383(7-8):1175-83.
2. Molecular cloning of the alpha-subunit of rat endopeptidase-24.18 (endopeptidase-2) and co-localization with endopeptidase-24.11 in rat kidney by in situ hybridization. Corbeil D, etal., FEBS Lett 1992 Sep 7;309(2):203-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Cloning a rat meprin cDNA reveals the enzyme is a heterodimer. Johnson GD and Hersh LB, J Biol Chem 1992 Jul 5;267(19):13505-12.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:7683677   PMID:8407940   PMID:8760356   PMID:9288916   PMID:11487543   PMID:12399461  


Genomics

Comparative Map Data
Mep1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8924,971,901 - 25,001,414 (+)NCBIGRCr8
mRatBN7.2917,474,634 - 17,504,147 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl917,474,619 - 17,504,147 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx926,065,182 - 26,095,281 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0931,139,752 - 31,169,851 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0929,428,977 - 29,459,076 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0920,048,163 - 20,077,678 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl920,048,121 - 20,077,702 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0918,925,181 - 18,953,891 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4913,170,762 - 13,201,094 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1913,168,083 - 13,198,416 (+)NCBI
Celera915,197,113 - 15,224,494 (+)NCBICelera
Cytogenetic Map9q13NCBI
MEP1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38646,793,389 - 46,845,984 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl646,793,389 - 46,839,778 (+)EnsemblGRCh38hg38GRCh38
GRCh37646,761,126 - 46,807,515 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36646,869,053 - 46,915,478 (+)NCBINCBI36Build 36hg18NCBI36
Build 34646,869,085 - 46,915,473NCBI
Celera648,313,551 - 48,359,899 (+)NCBICelera
Cytogenetic Map6p12.3NCBI
HuRef646,484,757 - 46,530,783 (+)NCBIHuRef
CHM1_1646,764,471 - 46,810,789 (+)NCBICHM1_1
T2T-CHM13v2.0646,631,036 - 46,683,461 (+)NCBIT2T-CHM13v2.0
Mep1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391743,785,215 - 43,815,034 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1743,785,215 - 43,813,703 (-)EnsemblGRCm39 Ensembl
GRCm381743,474,324 - 43,504,143 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1743,474,324 - 43,502,812 (-)EnsemblGRCm38mm10GRCm38
MGSCv371743,611,278 - 43,639,722 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361742,938,373 - 42,967,156 (-)NCBIMGSCv36mm8
Celera1746,896,845 - 46,925,249 (-)NCBICelera
Cytogenetic Map17B3NCBI
cM Map1719.73NCBI
Mep1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495543711,602,113 - 11,636,144 (+)NCBIChiLan1.0ChiLan1.0
MEP1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2561,294,694 - 61,337,889 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1657,160,890 - 57,204,126 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0646,382,105 - 46,425,300 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1647,647,721 - 47,690,331 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl647,647,721 - 47,691,070 (+)Ensemblpanpan1.1panPan2
MEP1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11214,966,215 - 15,004,069 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1214,966,209 - 15,003,867 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1214,997,039 - 15,035,329 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01215,465,854 - 15,500,412 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1215,465,839 - 15,500,421 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11214,981,007 - 15,015,182 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01215,070,190 - 15,108,254 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01215,216,475 - 15,254,182 (+)NCBIUU_Cfam_GSD_1.0
Mep1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494650,406,962 - 50,445,654 (+)NCBIHiC_Itri_2
SpeTri2.0NW_00493647613,514,965 - 13,553,209 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MEP1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1741,587,698 - 41,625,014 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2748,248,938 - 48,286,181 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MEP1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11725,439,415 - 25,479,092 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1725,439,442 - 25,473,681 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604446,813,671 - 46,854,220 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mep1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475413,845,949 - 13,865,792 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mep1a
183 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:502
Count of miRNA genes:267
Interacting mature miRNAs:316
Transcripts:ENSRNOT00000014791
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)9795472022071169Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 29 1
Low 4 1 3 1 2 12 5
Below cutoff 34 19 7 12 7 6 6 31 4 19 6 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000014791   ⟹   ENSRNOP00000014791
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl917,474,619 - 17,504,147 (+)Ensembl
Rnor_6.0 Ensembl920,048,121 - 20,077,702 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000105548   ⟹   ENSRNOP00000077952
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl917,474,619 - 17,504,147 (+)Ensembl
RefSeq Acc Id: NM_013143   ⟹   NP_037275
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8924,971,901 - 25,001,414 (+)NCBI
mRatBN7.2917,474,634 - 17,504,147 (+)NCBI
Rnor_6.0920,048,163 - 20,077,675 (+)NCBI
Rnor_5.0918,925,181 - 18,953,891 (+)NCBI
RGSC_v3.4913,170,762 - 13,201,094 (+)RGD
Celera915,197,113 - 15,224,494 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_037275 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB23030 (Get FASTA)   NCBI Sequence Viewer  
  AAH81834 (Get FASTA)   NCBI Sequence Viewer  
  EDM18694 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014791
  ENSRNOP00000014791.5
  ENSRNOP00000077952.1
GenBank Protein Q64230 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_037275   ⟸   NM_013143
- Peptide Label: precursor
- UniProtKB: Q642C9 (UniProtKB/Swiss-Prot),   Q64230 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014791   ⟸   ENSRNOT00000014791
RefSeq Acc Id: ENSRNOP00000077952   ⟸   ENSRNOT00000105548
Protein Domains
EGF-like   MAM   MATH   Peptidase M12A

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64230-F1-model_v2 AlphaFold Q64230 1-748 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696557
Promoter ID:EPDNEW_R7081
Type:multiple initiation site
Name:Mep1a_1
Description:meprin A subunit alpha
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0920,048,180 - 20,048,240EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:3080 AgrOrtholog
BioCyc Gene G2FUF-28105 BioCyc
Ensembl Genes ENSRNOG00000011022 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014791 ENTREZGENE
  ENSRNOT00000014791.8 UniProtKB/Swiss-Prot
  ENSRNOT00000105548.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.200 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7128404 IMAGE-MGC_LOAD
InterPro ConA-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAM_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MATH/TRAF_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Meprin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M12A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRAF-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRAF_MEP1_MATH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:25684 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93579 IMAGE-MGC_LOAD
NCBI Gene 25684 ENTREZGENE
PANTHER DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10127:SF824 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Astacin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRAF-mep_MATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mep1a PhenoGen
PIRSF Meprin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS ASTACIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAMDOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ASTACIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAM_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MAM_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_PROTEASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000011022 RatGTEx
SMART MAM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZnMc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49899 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRAF domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5Y808_RAT UniProtKB/TrEMBL
  A6JJ38_RAT UniProtKB/TrEMBL
  MEP1A_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q642C9 ENTREZGENE
UniProt Secondary Q642C9 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-03-29 Mep1a  meprin A subunit alpha  Mep1a  meprin 1 subunit alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2016-03-04 Mep1a  meprin 1 subunit alpha  Mep1a  meprin 1 alpha  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-12 Mep1a  meprin 1 alpha  LOC688307  similar to Meprin A alpha-subunit precursor (Endopeptidase-2) (MEP-1) (Endopeptidase-24.18 alpha-subunit) (E-24.18)  Data merged from RGD:1590063 737654 PROVISIONAL
2006-11-20 LOC688307  similar to Meprin A alpha-subunit precursor (Endopeptidase-2) (MEP-1) (Endopeptidase-24.18 alpha-subunit) (E-24.18)      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-06-10 Mep1a  Meprin 1 alpha      Symbol and Name status set to approved 70586 APPROVED