Gene: Smad2 (SMAD family member 2) Rattus norvegicus
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Symbol: Smad2
Name: SMAD family member 2
Description: ENCODES a protein that exhibits transcription factor binding; activating transcription factor binding (ortholog); chromatin binding (ortholog); INVOLVED IN negative regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; signal transduction involved in regulation of gene expression; PARTICIPATES IN transforming growth factor-beta Smad dependent signaling pathway; altered transforming growth factor-beta Smad dependent signaling pathway; colorectal cancer pathway; ASSOCIATED WITH Carcinoma, Hepatocellular; hepatocellular carcinoma; Hypoglossal Nerve Injuries; FOUND IN cytoplasm; nucleus; protein complex; INTERACTS WITH 2-acetamidofluorene; 2-amino-2-deoxy-D-galactopyranose; 2-methoxyethanol
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: MAD (mothers against decapentaplegic Drosophila) homolog 2; MAD (mothers against decapentaplegic, Drosophila) homolog 2; MAD homolog 2; MAD homolog 2 (Drosophila); mad-related protein 2; Madh2; MGC156656; mothers against decapentaplegic homolog 2; mothers against DPP homolog 2; SMAD 2
Orthologs:
Homo sapiens (human) : SMAD2 (SMAD family member 2)  HGNC
Mus musculus (house mouse) : Smad2 (SMAD family member 2)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Smad2 (SMAD family member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : SMAD2 (SMAD family member 2)
Canis lupus familiaris (dog) : SMAD2 (SMAD family member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Smad2 (SMAD family member 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01872,550,107 - 72,612,078 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01871,672,879 - 71,735,128 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41873,180,520 - 73,241,707 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11873,253,792 - 73,314,980 (+)NCBI
Celera1868,381,756 - 68,443,610 (+)NCBI
Cytogenetic Map18q12.3NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Smad2
NCBI Gene
Ensembl Gene
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RGD Object Information
RGD ID: 3031
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE