Gene: Kras (Kirsten rat sarcoma viral oncogene) Rattus norvegicus
Symbol: Kras
Name: Kirsten rat sarcoma viral oncogene
Description: ENCODES a protein that exhibits GDP binding; GMP binding; LRR domain binding; INVOLVED IN cytokine-mediated signaling pathway; liver development; positive regulation of cellular senescence; PARTICIPATES IN the extracellular signal-regulated Raf/Mek/Erk signaling pathway; altered extracellular signal-regulated Raf/Mek/Erk signaling pathway; endometrial cancer pathway; ASSOCIATED WITH Adenocarcinoma, Bronchiolo-Alveolar; Endometrial Neoplasms; Pancreatitis, Experimental, Acute ; FOUND IN membrane raft; mitochondrion; cytoplasm (ortholog); INTERACTS WITH 2,4-dinitrotoluene; 2-trans,6-trans-farnesyl diphosphate; 3-methyl-3H-imidazo[4,5-f]quinolin-2-amine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: c-K-ras; c-K-ras2 protein; c-Ki-ras; c-Kirsten-ras proto-oncogene; GTPase KRas; K-Ras 2; ki-Ras; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral oncogene homologue 2 (active); Kras2; p21; v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04179,483,086 - 179,515,609 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.04243,667,912 - 243,696,325 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.44182,869,242 - 182,895,106 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14183,114,365 - 183,140,230 (-)NCBI
Celera4166,708,846 - 166,734,692 (-)NCBI
Cytogenetic Map4q44NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Kras
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2981
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-05-03
Status: ACTIVE