Gene: Ins2 (insulin 2) Rattus norvegicus
Symbol: Ins2
Name: insulin 2
Description: ENCODES a protein that exhibits protease binding; protein complex binding; INVOLVED IN activation of MAPK activity (inferred); canonical Wnt signaling pathway (inferred); ER overload response (inferred); PARTICIPATES IN altered insulin signaling pathway; forkhead class A signaling pathway; insulin responsive facilitative sugar transporter mediated glucose transport pathway; ASSOCIATED WITH Alzheimer Disease; Diabetic Nephropathies; Hypertension; FOUND IN extracellular space; secretory granule; INTERACTS WITH (R)-adrenaline (ortholog); (R)-lipoic acid (ortholog); 17beta-estradiol (ortholog)
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: insulin-2
No known orthologs. homologs ...
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01215,856,967 - 215,858,034-NCBI
Rat Cytogenetic Map1q41 NCBI
RGSC Genome Assembly v5.01222,751,786 - 222,756,821-NCBI
RGSC Genome Assembly v3.41202,935,548 - 202,936,379-NCBI
Rat Celera Assembly1195,461,309 - 195,462,376-NCBI
Genome Assembly 3.11203,123,613 - 203,124,445-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Candidate Gene Status
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Ins2
Entrez Gene
Ensembl Gene
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RGD Object Information
RGD ID: 2916
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2015-03-18
Status: ACTIVE