Gene: Gck (glucokinase) Rattus norvegicus
Symbol: Gck
Name: glucokinase
Description: ENCODES a protein that exhibits ADP binding; ATP binding; glucokinase activity; INVOLVED IN carbohydrate phosphorylation; cellular glucose homeostasis; cellular response to glucose starvation; PARTICIPATES IN glycogen biosynthetic pathway; glycogen metabolic pathway; glycolysis pathway; ASSOCIATED WITH decreased circulating glucose level; increased circulating free fatty acid level; increased circulating triglyceride level; ASSOCIATED WITH Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fatty Liver; FOUND IN actin filament; basal cortex; cell cortex; INTERACTS WITH 1-naphthyl isothiocyanate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: glucokinase variant 3; GLUKA; hexokinase type IV; hexokinase-4; hexokinase-D; HK IV; HK4; RNGK2
Homo sapiens : GCK (glucokinase)  HGNC
Mus musculus : Gck (glucokinase)  MGI
more info ...
Is Marker For: QTLs:   Pancm5   Niddm37  
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01486,149,146 - 86,191,576-NCBI
Rat Cytogenetic Map14q21 NCBI
RGSC Genome Assembly v5.01486,832,735 - 86,875,295-NCBI
RGSC Genome Assembly v3.41486,572,518 - 86,587,723-NCBI
Rat Celera Assembly1479,669,432 - 79,710,739-NCBI
Genome Assembly 3.11486,591,662 - 86,606,868-NCBI

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QTLs in Region (RGSC Genome Assembly v5.0)
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Nucleotide Sequences
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Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gck
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RGD Object Information
RGD ID: 2670
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-01-26
Status: ACTIVE