Gene: Erbb2 (erb-b2 receptor tyrosine kinase 2) Rattus norvegicus
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Symbol: Erbb2
Name: erb-b2 receptor tyrosine kinase 2
Description: ENCODES a protein that exhibits Hsp90 protein binding; protein heterodimerization activity; protein tyrosine kinase activity; INVOLVED IN estrous cycle; glial cell differentiation; liver development; PARTICIPATES IN mitogen activated protein kinase signaling pathway; Ras mediated signaling pathway; altered epidermal growth factor/neuregulin signaling pathway; ASSOCIATED WITH increased metastatic potential; ASSOCIATED WITH congestive heart failure; Diabetic Cardiomyopathies; Heart Failure; FOUND IN apical plasma membrane; basal plasma membrane; basolateral plasma membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-acetamidofluorene; 3,3',5,5'-tetrabromobisphenol A
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Avian erythroblastosis viral (v-erb-B2) oncogene homologue 2 (neuro/glioblastoma derived oncogene homolog); C-erbB-2; epidermal growth factor receptor-related protein; NEU proto-oncogene; p185erbB2; p185neu; proto-oncogene c-ErbB-2; proto-oncogene NEU; receptor tyrosine-protein kinase erbB-2; v-erb-b2 avian erythroblastic leukemia viral oncogene 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
Orthologs:
Homo sapiens (human) : ERBB2 (erb-b2 receptor tyrosine kinase 2)  HGNC
Mus musculus (house mouse) : Erbb2 (erb-b2 receptor tyrosine kinase 2)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Erbb2 (erb-b2 receptor tyrosine kinase 2)
Pan paniscus (bonobo/pygmy chimpanzee) : ERBB2 (erb-b2 receptor tyrosine kinase 2)
Canis lupus familiaris (dog) : ERBB2 (erb-b2 receptor tyrosine kinase 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Erbb2 (erb-b2 receptor tyrosine kinase 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01086,367,596 - 86,391,728 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01086,163,531 - 86,187,663 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41087,219,157 - 87,242,919 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11087,233,617 - 87,256,603 (+)NCBI
Celera1082,158,844 - 82,182,518 (+)NCBI
Cytogenetic Map10q31NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
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QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences