Mir205 (microRNA 205) - Rat Genome Database

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Gene: Mir205 (microRNA 205) Rattus norvegicus
Analyze
Symbol: Mir205
Name: microRNA 205
RGD ID: 2325377
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing translational repressor activity. Predicted to be involved in miRNA-mediated gene silencing by inhibition of translation; negative regulation of fibroblast growth factor production; and negative regulation of vascular endothelial growth factor production. Predicted to act upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation of cell population proliferation; and positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction. Orthologous to human MIR205 (microRNA 205); INTERACTS WITH 2-acetamidofluorene; aflatoxin B1; amphetamine.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-205; rno-mir-205
RGD Orthologs
Human
Mouse
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813107,564,535 - 107,564,642 (-)NCBIGRCr8
mRatBN7.213105,035,878 - 105,035,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13105,035,878 - 105,035,985 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13107,553,462 - 107,553,569 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,937,334 - 108,937,441 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013106,155,314 - 106,155,421 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013112,233,283 - 112,233,390 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13112,233,283 - 112,233,390 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,787,618 - 116,787,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera13104,464,695 - 104,464,802 (-)NCBICelera
Cytogenetic Map13q27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12554859   PMID:16381832   PMID:18762567   PMID:20103531   PMID:20403161   PMID:20439489   PMID:21628588   PMID:23646144   PMID:23974039   PMID:24205035   PMID:25961955   PMID:28849082  
PMID:30729682   PMID:31062423   PMID:31858563   PMID:34078833   PMID:34196265   PMID:35166074   PMID:36705422  


Genomics

Comparative Map Data
Mir205
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr813107,564,535 - 107,564,642 (-)NCBIGRCr8
mRatBN7.213105,035,878 - 105,035,985 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl13105,035,878 - 105,035,985 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx13107,553,462 - 107,553,569 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.013108,937,334 - 108,937,441 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.013106,155,314 - 106,155,421 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.013112,233,283 - 112,233,390 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl13112,233,283 - 112,233,390 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.013116,787,618 - 116,787,725 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera13104,464,695 - 104,464,802 (-)NCBICelera
Cytogenetic Map13q27NCBI
MIR205
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381209,432,133 - 209,432,242 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1209,432,133 - 209,432,242 (+)EnsemblGRCh38hg38GRCh38
GRCh371209,605,478 - 209,605,587 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361207,672,100 - 207,672,209 (+)NCBINCBI36Build 36hg18NCBI36
Celera1182,836,332 - 182,836,441 (+)NCBICelera
Cytogenetic Map1q32.2NCBI
HuRef1180,280,840 - 180,280,949 (+)NCBIHuRef
CHM1_11210,877,809 - 210,877,918 (+)NCBICHM1_1
T2T-CHM13v2.01208,678,941 - 208,679,050 (+)NCBIT2T-CHM13v2.0
Mir205
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391193,189,771 - 193,189,838 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1193,189,771 - 193,189,838 (-)EnsemblGRCm39 Ensembl
GRCm381193,507,463 - 193,507,530 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1193,507,463 - 193,507,530 (-)EnsemblGRCm38mm10GRCm38
MGSCv371195,333,657 - 195,333,724 (-)NCBIGRCm37MGSCv37mm9NCBIm37
Celera1200,390,095 - 200,390,162 (-)NCBICelera
Cytogenetic Map1H6NCBI
cM Map197.82NCBI
MIR205
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.178,090,511 - 8,090,579 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl78,090,511 - 8,090,579 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha77,668,330 - 7,668,398 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.077,791,121 - 7,791,189 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl77,791,121 - 7,791,189 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.177,721,572 - 7,721,640 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.077,818,519 - 7,818,587 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.077,879,407 - 7,879,475 (+)NCBIUU_Cfam_GSD_1.0
MIR205
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9133,517,078 - 133,517,146 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19133,517,078 - 133,517,146 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29146,808,292 - 146,808,360 (-)NCBISscrofa10.2Sscrofa10.2susScr3

miRNA Target Status

Predicted Targets
Summary Value
Count of predictions:3948
Count of gene targets:3075
Count of transcripts:3300
Interacting mature miRNAs:rno-miR-205
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1361825626106807694Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1365103704106807694Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1365103704106807694Rat
4889606Gluco63Glucose level QTL 632.860.003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1380753256106807694Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system hemolymphoid system integumental system musculoskeletal system renal system reproductive system respiratory system appendage
High
Medium
Low 2 7 7 1 1 2 5 1
Below cutoff 1 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NR_031920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000053643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl13105,035,878 - 105,035,985 (-)Ensembl
Rnor_6.0 Ensembl13112,233,283 - 112,233,390 (-)Ensembl
RefSeq Acc Id: NR_031920
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr813107,564,535 - 107,564,642 (-)NCBI
mRatBN7.213105,035,878 - 105,035,985 (-)NCBI
Rnor_6.013112,233,283 - 112,233,390 (-)NCBI
Rnor_5.013116,787,618 - 116,787,725 (-)NCBI
Celera13104,464,695 - 104,464,802 (-)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325377 AgrOrtholog
BioCyc Gene G2FUF-16781 BioCyc
Ensembl Genes ENSRNOG00000035520 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053643 ENTREZGENE
miRBase MI0000947 ENTREZGENE
NCBI Gene 100314246 ENTREZGENE
PhenoGen Mir205 PhenoGen
RatGTEx ENSRNOG00000035520 RatGTEx
RNAcentral URS0000220D63 RNACentral
  URS000075A278 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Mir205  microRNA 205  Mir205  microRNA mir-205  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-06-02 Mir205  microRNA mir-205      Symbol and Name status set to provisional 70820 PROVISIONAL