Gene: App (amyloid beta precursor protein) Rattus norvegicus
Symbol: App
Name: amyloid beta precursor protein
Description: ENCODES a protein that exhibits growth factor receptor binding; peptidase activator activity; acetylcholine receptor binding (ortholog); INVOLVED IN cellular response to cAMP; cellular response to nerve growth factor stimulus; cellular response to norepinephrine stimulus; PARTICIPATES IN glypican signaling pathway; Alzheimer disease pathway; ASSOCIATED WITH Anemia, Iron-Deficiency; Blast Injuries; Chronic Cerebral Hypoperfusion; FOUND IN astrocyte projection; axon; cell surface; INTERACTS WITH (+)-catechin; (S)-naringenin; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Abeta; ABPP; AG; alzheimer disease amyloid A4 protein homolog; amyloid A4; amyloid beta (A4) precursor protein; amyloid beta A4 protein; amyloidogenic glycoprotein
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01124,425,013 - 24,641,872 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01128,048,897 - 28,265,250 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41124,457,855 - 24,693,851 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11124,457,854 - 24,693,851 (-)NCBI
Celera1123,853,696 - 24,069,048 (-)NCBI
Cytogenetic Map11q11NCBImapview
RH 3.4 Map1194.7RGD
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Candidate Gene Status
Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on App
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 2139
Created: 2000-05-25
Species: Rattus norvegicus
Last Modified: 2016-08-23
Status: ACTIVE