Hbb-bs (hemoglobin, beta adult s chain) - Rat Genome Database

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Gene: Hbb-bs (hemoglobin, beta adult s chain) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Hbb-bs (Ensembl: Hbb)
Name: hemoglobin, beta adult s chain (Ensembl:hemoglobin subunit beta)
RGD ID: 1597422
Description: Predicted to enable heme binding activity; metal ion binding activity; and oxygen carrier activity. Predicted to be involved in nitric oxide transport and oxygen transport. Predicted to be part of hemoglobin complex. Human ortholog(s) of this gene implicated in acute chest syndrome; hemolytic anemia (multiple); malaria; polycythemia (multiple); and sickle cell anemia. Orthologous to human HBB (hemoglobin subunit beta) and HBD (hemoglobin subunit delta).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: beta-2-globin; beta-globin; beta-hemoglobin; hemoglobin beta chain, minor-form; hemoglobin beta-2 chain; hemoglobin subunit beta-2; III beta-3 globin; LOC103694857; LOC689064
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81167,630,245 - 167,631,630 (-)NCBIGRCr8
mRatBN7.21158,218,356 - 158,219,741 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1158,120,200 - 158,252,012 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1166,216,373 - 166,217,758 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01173,396,390 - 173,397,775 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01166,284,588 - 166,285,973 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,964,202 - 168,965,568 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,945,449 - 168,965,566 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01175,098,754 - 175,100,120 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41161,578,126 - 161,579,492 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1156,255,533 - 156,256,825 (-)NCBICelera
Cytogenetic Map1q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Differential gene expression pattern of diabetic rat retinas after intravitreal injection of erythropoietin. Chu Q, etal., Clin Experiment Ophthalmol. 2011 Mar;39(2):142-51. doi: 10.1111/j.1442-9071.2010.02437.x.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
4. Functional alterations in adult and fetal hemoglobin Sassari Asp-alpha 126(H9)-->His. The role of alpha 1 alpha 2 contact. Sanna MT, etal., J Biol Chem. 1994 Jul 15;269(28):18338-42.
Additional References at PubMed
PMID:2263193   PMID:2587229   PMID:2748344   PMID:2777087   PMID:3357786   PMID:3453111   PMID:22516433   PMID:29476059  


Genomics

Variants

.
Variants in Hbb-bs
14 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
2313060Bss71Bone structure and strength QTL 712.60.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1118944747163944747Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121833674166833674Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501168883176Rat
9685799Bp375Blood pressure QTL 375arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
631202Gluco13Glucose level QTL 130.0001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1131763437159756369Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
631206Niddm40Non-insulin dependent diabetes mellitus QTL 40blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1136745990163747690Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1144267916172949660Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144267916174133260Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1155422851172949803Rat
4889419Cstrr2Cold stress response QTL 20.05urine catecholamine amount (VT:0010502)absolute change in urine norepinephrine level (CMO:0001634)1155866514158592016Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1156677124176484451Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat

Markers in Region
AI036344  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21158,218,397 - 158,218,506 (-)MAPPERmRatBN7.2
Rnor_6.01168,965,418 - 168,965,526NCBIRnor6.0
Rnor_5.01175,098,796 - 175,098,904UniSTSRnor5.0
RGSC_v3.41161,578,168 - 161,578,276UniSTSRGSC3.4
Cytogenetic Map1q32UniSTS
Hbb-b1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1156,262,234 - 156,262,291UniSTS
Celera1156,256,379 - 156,256,436UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map1q22UniSTS
Hbb-b1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21158,243,935 - 158,244,689 (-)MAPPERmRatBN7.2
mRatBN7.21158,218,599 - 158,219,353 (-)MAPPERmRatBN7.2
mRatBN7.21158,237,209 - 158,237,963 (-)MAPPERmRatBN7.2
Rnor_6.01168,964,571 - 168,965,324NCBIRnor6.0
Rnor_6.01168,957,845 - 168,958,598NCBIRnor6.0
Rnor_5.01175,098,998 - 175,099,751UniSTSRnor5.0
Rnor_5.01175,128,184 - 175,128,937UniSTSRnor5.0
Celera1156,255,703 - 156,256,456UniSTS
Cytogenetic Map1q22UniSTS
Cytogenetic Map1q32UniSTS
Hbb-b1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Celera1156,261,406 - 156,262,441UniSTS
Celera1156,255,595 - 156,256,586UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map1q22UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001111269 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC113925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY319996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ209902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210742 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217477 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218287 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221211 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ225765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ226110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228130 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230470 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ230899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ231257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27170 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M27173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X06701 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X67616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000019913   ⟹   ENSRNOP00000019914
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,236,972 - 158,238,356 (-)Ensembl
Rnor_6.0 Ensembl1168,945,567 - 168,953,025 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087661   ⟹   ENSRNOP00000068875
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,218,358 - 158,231,777 (-)Ensembl
Rnor_6.0 Ensembl1168,945,449 - 168,965,566 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089102   ⟹   ENSRNOP00000072853
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,218,357 - 158,231,637 (-)Ensembl
Rnor_6.0 Ensembl1168,964,202 - 168,965,566 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000089125   ⟹   ENSRNOP00000068726
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,120,200 - 158,251,837 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090422   ⟹   ENSRNOP00000070324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,224,173 - 158,238,388 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090678   ⟹   ENSRNOP00000069937
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,218,358 - 158,238,511 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000090745   ⟹   ENSRNOP00000071528
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,243,698 - 158,245,082 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099220   ⟹   ENSRNOP00000084256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,218,358 - 158,252,012 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113702   ⟹   ENSRNOP00000091885
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,224,162 - 158,238,511 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114441   ⟹   ENSRNOP00000085307
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1158,243,694 - 158,251,868 (-)Ensembl
RefSeq Acc Id: NM_001111269   ⟹   NP_001104739
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81167,630,245 - 167,631,630 (-)NCBI
mRatBN7.21158,218,356 - 158,219,741 (-)NCBI
Rnor_6.01168,964,202 - 168,965,568 (+)NCBI
Rnor_5.01175,098,754 - 175,100,120 (-)NCBI
RGSC_v3.41161,578,126 - 161,579,492 (-)RGD
Celera1156,255,533 - 156,256,825 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_001104739   ⟸   NM_001111269
- UniProtKB: P11517 (UniProtKB/Swiss-Prot),   A0A1K0FUA6 (UniProtKB/TrEMBL),   A0A1K0GGD1 (UniProtKB/TrEMBL),   A0A0G2JTW9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072853   ⟸   ENSRNOT00000089102
RefSeq Acc Id: ENSRNOP00000068875   ⟸   ENSRNOT00000087661
RefSeq Acc Id: ENSRNOP00000019914   ⟸   ENSRNOT00000019913
RefSeq Acc Id: ENSRNOP00000070324   ⟸   ENSRNOT00000090422
RefSeq Acc Id: ENSRNOP00000085307   ⟸   ENSRNOT00000114441
RefSeq Acc Id: ENSRNOP00000084256   ⟸   ENSRNOT00000099220
RefSeq Acc Id: ENSRNOP00000071528   ⟸   ENSRNOT00000090745
RefSeq Acc Id: ENSRNOP00000069937   ⟸   ENSRNOT00000090678
RefSeq Acc Id: ENSRNOP00000068726   ⟸   ENSRNOT00000089125
RefSeq Acc Id: ENSRNOP00000091885   ⟸   ENSRNOT00000113702
Protein Domains
Globin family profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P11517-F1-model_v2 AlphaFold P11517 1-147 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690274
Promoter ID:EPDNEW_R799
Type:multiple initiation site
Name:LOC103694857_1
Description:hemoglobin subunit beta-2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01168,964,184 - 168,964,244EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1597422 AgrOrtholog
BioCyc Gene G2FUF-58137 BioCyc
Ensembl Genes ENSRNOG00000047098 Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055029894 UniProtKB/Swiss-Prot
  ENSRNOG00055029899 UniProtKB/Swiss-Prot
  ENSRNOG00060016593 UniProtKB/Swiss-Prot
  ENSRNOG00060016605 UniProtKB/Swiss-Prot
  ENSRNOG00065031394 UniProtKB/Swiss-Prot
  ENSRNOG00065031400 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019913.7 UniProtKB/Swiss-Prot
  ENSRNOT00000087661.2 UniProtKB/TrEMBL
  ENSRNOT00000089102.2 UniProtKB/TrEMBL
  ENSRNOT00000090422.2 UniProtKB/TrEMBL
  ENSRNOT00000090678.2 UniProtKB/TrEMBL
  ENSRNOT00000090745.2 UniProtKB/Swiss-Prot
  ENSRNOT00000099220.1 UniProtKB/TrEMBL
  ENSRNOT00055051796 UniProtKB/Swiss-Prot
  ENSRNOT00055051811 UniProtKB/Swiss-Prot
  ENSRNOT00060028408 UniProtKB/Swiss-Prot
  ENSRNOT00060028432 UniProtKB/Swiss-Prot
  ENSRNOT00065054117 UniProtKB/Swiss-Prot
  ENSRNOT00065054126 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.490.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Globin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Globin-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Globin/Proto UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Haemoglobin_b UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:100134871 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  rno:689064 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 689064 ENTREZGENE
PANTHER HEMOGLOBIN FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEMOGLOBIN SUBUNIT BETA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Globin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hbb-bs PhenoGen
PRINTS BETAHAEM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLOBIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000047098 RatGTEx
  ENSRNOG00055029894 RatGTEx
  ENSRNOG00055029899 RatGTEx
  ENSRNOG00060016593 RatGTEx
  ENSRNOG00060016605 RatGTEx
  ENSRNOG00065031394 RatGTEx
  ENSRNOG00065031400 RatGTEx
Superfamily-SCOP SSF46458 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JSW3_RAT UniProtKB/TrEMBL
  A0A0G2JTW9 ENTREZGENE, UniProtKB/TrEMBL
  A0A1K0FUA6 ENTREZGENE, UniProtKB/TrEMBL
  A0A1K0GGD1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZXF1_RAT UniProtKB/TrEMBL
  A0A8L2R1Q6_RAT UniProtKB/TrEMBL
  A0A8L2R6L7_RAT UniProtKB/TrEMBL
  HBB2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Hbb-bs  hemoglobin, beta adult s chain  LOC103694857  hemoglobin subunit beta-2  Data merged from RGD:9218369 737654 PROVISIONAL
2019-08-08 Hbb-bs  hemoglobin, beta adult s chain  LOC689064  beta-globin  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2014-08-25 LOC103694857  hemoglobin subunit beta-2      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC689064  beta-globin      Symbol and Name status set to provisional 70820 PROVISIONAL