Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Neoplasm Invasiveness | | ISO | ITPK1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:26213588 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Neoplasm Invasiveness | | ISO | ITPK1 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:26213588 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
3. | SMPDB Annotation Import Pipeline | Pipeline to import SMPDB annotations from SMPDB into RGD |
4. | GOA pipeline | RGD automated data pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
PMID:8662638 | PMID:11042108 | PMID:16537650 | PMID:19482943 | PMID:29883610 |
Itpk1 (Rattus norvegicus - Norway rat) |
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ITPK1 (Homo sapiens - human) |
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Itpk1 (Mus musculus - house mouse) |
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Itpk1 (Chinchilla lanigera - long-tailed chinchilla) |
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ITPK1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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ITPK1 (Canis lupus familiaris - dog) |
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Itpk1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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ITPK1 (Sus scrofa - pig) |
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ITPK1 (Chlorocebus sabaeus - green monkey) |
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Itpk1 (Heterocephalus glaber - naked mole-rat) |
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Variants in Itpk1
510 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
D6Hmgc8 |
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D6Hmgc9 |
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AU048745 |
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AU046664 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 3 | 21 | 5 | 18 | 5 | 70 | 22 | 28 | 11 | ||||
Low | 43 | 36 | 36 | 1 | 36 | 8 | 11 | 4 | 13 | 13 | 8 | ||
Below cutoff |
RefSeq Transcripts | NM_001191985 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_008764841 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008764842 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594304 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594305 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594306 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017594307 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039112755 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063262333 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063262334 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC108241 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AC109025 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473982 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ211635 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000006 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000010656 ⟹ ENSRNOP00000010656 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000080829 ⟹ ENSRNOP00000074255 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000095173 ⟹ ENSRNOP00000097242 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000095210 ⟹ ENSRNOP00000097430 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000119725 ⟹ ENSRNOP00000091296 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001191985 ⟹ NP_001178914 | ||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_008764842 ⟹ XP_008763064 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017594304 ⟹ XP_017449793 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039112755 ⟹ XP_038968683 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_063262333 ⟹ XP_063118403 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063262334 ⟹ XP_063118404 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001178914 | (Get FASTA) | NCBI Sequence Viewer |
XP_008763064 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017449793 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038968683 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063118403 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063118404 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | EDL81754 | (Get FASTA) | NCBI Sequence Viewer |
EDL81755 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000010656 | ||
ENSRNOP00000010656.7 | |||
ENSRNOP00000074255 | |||
ENSRNOP00000074255.1 | |||
ENSRNOP00000091296.1 | |||
ENSRNOP00000097242 | |||
ENSRNOP00000097242.1 | |||
ENSRNOP00000097430.1 |
RefSeq Acc Id: | NP_001178914 ⟸ NM_001191985 |
- UniProtKB: | D3ZQM7 (UniProtKB/TrEMBL), A0A8I6AUY6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_008763064 ⟸ XM_008764842 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A8I6AUY6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017449793 ⟸ XM_017594304 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A0G2K7L4 (UniProtKB/TrEMBL), A0A8I6AUY6 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000074255 ⟸ ENSRNOT00000080829 |
RefSeq Acc Id: | ENSRNOP00000010656 ⟸ ENSRNOT00000010656 |
RefSeq Acc Id: | XP_038968683 ⟸ XM_039112755 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | ENSRNOP00000097242 ⟸ ENSRNOT00000095173 |
RefSeq Acc Id: | ENSRNOP00000091296 ⟸ ENSRNOT00000119725 |
RefSeq Acc Id: | ENSRNOP00000097430 ⟸ ENSRNOT00000095210 |
RefSeq Acc Id: | XP_063118404 ⟸ XM_063262334 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_063118403 ⟸ XM_063262333 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A8I6AUQ3 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-A0A0G2K7L4-F1-model_v2 | AlphaFold | A0A0G2K7L4 | 1-463 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13694785 | ||||||||
Promoter ID: | EPDNEW_R5309 | ||||||||
Type: | initiation region | ||||||||
Name: | Itpk1_1 | ||||||||
Description: | inositol-tetrakisphosphate 1-kinase | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1595691 | AgrOrtholog |
BioCyc Gene | G2FUF-36445 | BioCyc |
Ensembl Genes | ENSRNOG00000008051 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000010656 | ENTREZGENE |
ENSRNOT00000010656.8 | UniProtKB/TrEMBL | |
ENSRNOT00000080829.2 | UniProtKB/TrEMBL | |
ENSRNOT00000095173.1 | UniProtKB/TrEMBL | |
ENSRNOT00000095210.1 | UniProtKB/TrEMBL | |
ENSRNOT00000119725.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 3.30.1490.220 | UniProtKB/TrEMBL |
3.40.50.11370 | UniProtKB/TrEMBL | |
ATP-grasp fold, B domain | UniProtKB/TrEMBL | |
InterPro | ATP-grasp | UniProtKB/TrEMBL |
Ins134_P3_kin | UniProtKB/TrEMBL | |
InsP(3)kin_ATP-grasp | UniProtKB/TrEMBL | |
ITPK1_N | UniProtKB/TrEMBL | |
KEGG Report | rno:500709 | UniProtKB/TrEMBL |
NCBI Gene | 500709 | ENTREZGENE |
PANTHER | INOSITOL-TETRAKISPHOSPHATE 1-KINASE | UniProtKB/TrEMBL |
PTHR14217 | UniProtKB/TrEMBL | |
Pfam | Ins134_P3_kin | UniProtKB/TrEMBL |
Ins134_P3_kin_N | UniProtKB/TrEMBL | |
PhenoGen | Itpk1 | PhenoGen |
PROSITE | ATP_GRASP | UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000008051 | RatGTEx |
Superfamily-SCOP | Glutathione synthetase ATP-binding domain-like | UniProtKB/TrEMBL |
UniProt | A0A0G2K7L4 | ENTREZGENE, UniProtKB/TrEMBL |
A0A8I6AFB6_RAT | UniProtKB/TrEMBL | |
A0A8I6AUQ3 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8I6AUY6 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZQM7 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2013-05-24 | Itpk1 | inositol-tetrakisphosphate 1-kinase | LOC683482 | similar to inositol 1,3,4-triphosphate 5/6 kinase | Data merged from RGD:1586809 | 1643240 | APPROVED |
2011-08-02 | Itpk1 | inositol-tetrakisphosphate 1-kinase | Itpk1 | inositol 1,3,4-triphosphate 5/6 kinase | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-03-05 | Itpk1 | inositol 1,3,4-triphosphate 5/6 kinase | LOC500709 | similar to inositol 1,3,4-triphosphate 5/6 kinase | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2006-11-20 | LOC500709 | similar to inositol 1,3,4-triphosphate 5/6 kinase | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2006-11-19 | LOC683482 | similar to inositol 1,3,4-triphosphate 5/6 kinase | Symbol and Name status set to provisional | 70820 | PROVISIONAL |