Csf2ra (colony stimulating factor 2 receptor subunit alpha)

Gene: Csf2ra (colony stimulating factor 2 receptor subunit alpha) Rattus norvegicus

Analyze

Symbol:

Csf2ra

Name:

colony stimulating factor 2 receptor subunit alpha

RGD ID:

1594330

Description:

Predicted to enable granulocyte colony-stimulating factor binding activity and granulocyte colony-stimulating factor receptor activity. Involved in response to ethanol. Predicted to be located in plasma membrane. Predicted to be part of granulocyte macrophage colony-stimulating factor receptor complex. Human ortholog(s) of this gene implicated in pulmonary alveolar proteinosis. Orthologous to human CSF2RA (colony stimulating factor 2 receptor subunit alpha); PARTICIPATES IN granulocyte-macrophage colony-stimulating factor signaling pathway; cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

colony stimulating factor 2 receptor alpha subunit; colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage); granulocyte-macrophage colony stimulating receptor alpha; granulocyte-macrophage colony-stimulating factor receptor subunit alpha

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	113,219 - 118,808 (-)	NCBI		GRCr8
mRatBN7.2	14	98,089 - 103,261 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	89,172 - 103,128 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	116,168 - 121,062 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	1,417,943 - 1,422,837 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	114,615 - 119,509 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	1,462,292 - 1,467,264 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	1,462,358 - 1,467,264 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	1,465,139 - 1,469,667 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	14	661,818 - 666,688 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

pulmonary alveolar proteinosis (ISO,ISS)

Pulmonary Surfactant Metabolism Dysfunction 4 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-methylcholine (ISO)

3,4-methylenedioxymethamphetamine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

acetamide (EXP)

antirheumatic drug (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP)

butan-1-ol (ISO)

butanal (ISO)

cannabidiol (EXP)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

cocaine (EXP)

crocidolite asbestos (ISO)

curcumin (ISO)

dibutyl phthalate (EXP)

dioxygen (ISO)

dorsomorphin (ISO)

entinostat (ISO)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

hydrogen peroxide (ISO)

L-methionine (ISO)

lead diacetate (ISO)

lidocaine (EXP)

lipopolysaccharide (ISO)

maneb (ISO)

mercury dibromide (ISO)

nickel atom (ISO)

ozone (ISO)

panobinostat (ISO)

paracetamol (ISO)

paraquat (ISO)

pentanal (ISO)

phenylmercury acetate (ISO)

pluronic P-123 (ISO)

Poloxamer (ISO)

progesterone (ISO)

propanal (ISO)

rotenone (EXP)

SB 431542 (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

tetraphene (ISO)

titanium dioxide (ISO)

topotecan (ISO)

trichloroethene (EXP,ISO)

trichostatin A (ISO)

valproic acid (ISO)

vancomycin (ISO)

zidovudine (ISO)

zinc atom (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell surface receptor signaling pathway via JAK-STAT (ISO)

granulocyte-macrophage colony-stimulating factor signaling pathway (ISO)

positive regulation of leukocyte proliferation (ISO)

response to ethanol (IEP)

Cellular Component

external side of plasma membrane (IEA)

granulocyte macrophage colony-stimulating factor receptor complex (ISO)

Molecular Function

cytokine receptor activity (IEA)

erythropoietin receptor activity (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

cytokine mediated signaling pathway (IEA)

granulocyte-macrophage colony-stimulating factor signaling pathway (ISO)

Jak-Stat signaling pathway (IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Cloning of rat interleukin-3 receptor beta-subunit from cultured microglia and its mRNA expression in vivo.	Appel K, etal., J Neurosci 1995 Aug;15(8):5800-9.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GM-CSF receptor expression and signaling is decreased in lungs of ethanol-fed rats.	Joshi PC, etal., Am J Physiol Lung Cell Mol Physiol. 2006 Dec;291(6):L1150-8. Epub 2006 Jul 28.
4.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
5.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
6.	GOA pipeline	RGD automated data pipeline
7.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
9.	Comprehensive gene review and curation	RGD comprehensive gene curation

Additional References at PubMed

PMID:17694571

Genomics

Comparative Map Data

Csf2ra
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	14	113,219 - 118,808 (-)	NCBI		GRCr8
mRatBN7.2	14	98,089 - 103,261 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	14	89,172 - 103,128 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	14	116,168 - 121,062 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	14	1,417,943 - 1,422,837 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	14	114,615 - 119,509 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	14	1,462,292 - 1,467,264 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	14	1,462,358 - 1,467,264 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	14	1,465,139 - 1,469,667 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
Celera	14	661,818 - 666,688 (+)	NCBI		Celera
Cytogenetic Map	14	p22	NCBI

CSF2RA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	Y	1,268,814 - 1,325,218 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38	X	1,268,814 - 1,325,218 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	X	1,268,800 - 1,310,381 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p14 Ensembl	Y	1,268,800 - 1,310,381 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	Y	1,337,707 - 1,394,111 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
GRCh37	X	1,387,707 - 1,444,111 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	Y	1,347,701 - 1,388,827 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 36	X	1,347,701 - 1,388,827 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	Y	1,355,172 - 1,396,299	NCBI
Celera	X	5,684,057 - 5,726,879 (+)	NCBI		Celera
Cytogenetic Map	X	;Y	NCBI
CHM1_1	X	1,418,017 - 1,458,211 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	Y	1,129,416 - 1,189,240 (+)	NCBI		T2T-CHM13v2.0
T2T-CHM13v2.0	X	1,116,126 - 1,174,802 (+)	NCBI		T2T-CHM13v2.0

Csf2ra
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	19	61,205,629 - 61,221,141 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	19	61,212,395 - 61,216,867 (-)	Ensembl		GRCm39 Ensembl
GRCm38	19	61,217,191 - 61,228,461 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	19	61,223,957 - 61,228,429 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	19	61,300,305 - 61,304,321 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	19	61,279,074 - 61,283,022 (-)	NCBI		MGSCv36	mm8
Celera	19	63,421,543 - 63,425,590 (-)	NCBI		Celera
Cytogenetic Map	19	D3	NCBI
cM Map	19	56.89	NCBI

CSF2RA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	X	832,170 - 855,548 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	X	832,046 - 853,876 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	X	772,774 - 796,202 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	X	742,740 - 766,122 (+)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	X	734,899 - 758,240 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	X	751,242 - 774,663 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	X	748,192 - 771,608 (+)	NCBI		UU_Cfam_GSD_1.0

LOC101965277
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404953	534,206 - 541,365 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936644	3,835,462 - 3,842,471 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CSF2RA
(Sus scrofa - pig)

No map positions available.

LOC103247514
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666141	112,013 - 168,815 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Csf2ra
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624834	616,180 - 628,794 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Csf2ra
19 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	59
Count of miRNA genes:	51
Interacting mature miRNAs:	52
Transcripts:	ENSRNOT00000070834
Prediction methods:	Microtar, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2300159	Bmd61	Bone mineral density QTL 61	5.3	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
2300183	Bmd60	Bone mineral density QTL 60	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	14	1	26541967	Rat
619619	Rf4	Renal disease susceptibility QTL 4	4.1	0.002	urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	14	1	32754612	Rat
634352	Apr6	Acute phase response QTL 6	3.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	14	1	41131407	Rat

Markers in Region

RH134866

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	97,901 - 98,102 (-)	MAPPER	mRatBN7.2
Rnor_6.0	14	1,467,396 - 1,467,596	NCBI	Rnor6.0
Rnor_5.0	14	1,469,799 - 1,469,999	UniSTS	Rnor5.0
Celera	14	666,820 - 667,020	UniSTS

RH140244

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	14	98,313 - 98,612 (-)	MAPPER	mRatBN7.2
Rnor_6.0	14	1,466,886 - 1,467,184	NCBI	Rnor6.0
Rnor_5.0	14	1,469,289 - 1,469,587	UniSTS	Rnor5.0
Celera	14	666,310 - 666,608	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2		14	13	12	13			33	6	27	9
Low	1	43	43	28	7	28	8	11	41	29	14	2	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001037660	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599372	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599373	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599374	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599375	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039092399	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273579	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273581	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273582	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063273583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AJ628424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ227236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000014	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000070834 ⟹ ENSRNOP00000064492

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	98,236 - 103,128 (-)	Ensembl
Rnor_6.0 Ensembl	14	1,463,359 - 1,467,054 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000077243 ⟹ ENSRNOP00000075442

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	98,236 - 103,128 (-)	Ensembl
Rnor_6.0 Ensembl	14	1,462,358 - 1,467,264 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106970 ⟹ ENSRNOP00000097127

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	14	89,172 - 103,128 (-)	Ensembl

RefSeq Acc Id:

NM_001037660 ⟹ NP_001032749

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	113,223 - 118,117 (-)	NCBI
mRatBN7.2	14	98,234 - 103,128 (-)	NCBI
Rnor_6.0	14	1,462,358 - 1,467,264 (+)	NCBI
Rnor_5.0	14	1,465,139 - 1,469,667 (+)	NCBI
Celera	14	661,818 - 666,688 (+)	RGD

Sequence:

show sequence

TCTCAGGCATCCCCCTGCCTCAGTTGGGCCATGAGCATCATTCCCCTGCCTCAGCTCCTCGCCC
TGCTCTGCTGCTGCGGACTTGCTGCTGCTACTCAGGGCCCCACAGACCCGTCCACGCCCCCTAA
CCTGGGCCTCGCCCACTTCCACAACCTGACCTTCGACCCCGGGACCTGGACACTGAGCTGGGCC
TGTGGCGGCCATGATGGGGCAGTGATGTCGTGCACGGTGATTGACCAGGAGGCAGGGATCCGGC
GCAGAGTGCGGTCCCGGGGCTGCCGCTGCCGGTTTCAGCCAATGGAGTTACACCGCGGGGTCGA
CCTGGAGGTTGCGGGGGACAAAGGCCATGCCCAAGTCCATCAGACTCTGCGCTTCGAGAATGAA
GGTGCCCCAGGCTCCGGGGCAGAGAACCTGACCTGTGAGATCCTTGCTGCCCACTTCCTGTGCT
GTTATTGGGCGGTGGGGCCGGCTGCACCCGATGACATCAGATACTCACTGCGCGTGCTCAACGC
CACTGGTCATGAGGTCGCCAGCTGCTCCGCTGCCCCCGGAACCCCACCCACGCGTTGCCAGGCT
GATGATCTCACACATCTGCCCCGCCTCGCATACATCGTCGTCACTGGGCAGAGCCGGACGGGGC
TGGTGCGGTTCCTGGATGCCGTGGTCAACACCAAGGGCATTGAGCGCCTGGGTCCCCCAGATAA
CGTCTCTGCCTCCTGTAACTTCTCCCACTGCACCATCACCTGGGCTCCGCCCCCTACCTGGGCG
CCTATGACGGAACAGGATTTCCGCTTTGAGATCGAGTGGAAGAAGGCGGAGCCCAGCAGCATTG
CCCAGAAGGTGGTTATCGCAGGGCGCGAGGACAACGCCTTCGCCTTCCCCAGCCCCGCCCCCCG
TGGCCGCCTCTGGGTCAGAGTTCGTGCAGGGGACACACGCAGTGATCGGTGGAGCGACTGGAGC
CCCGCCCTGGAGCTCGGCTCGGAGGCCACAACCCCGCCGCGGGCCCTGGTGTTGGCGGCGTCGA
GCTGTGCAGCCCTGCTGTGTGCGCTGGCACTGGGGGCGGCCTGCAGGAGACTCGCGCTCTCACG
CCGCCTCCTCCCCCCCATCCCCGGGATCCGGGACCGCGTATCTGATGACGAGCGTGTCAACTCG
GAGACGCTGAGGAAGGACCTGCTGCGGCCCTAGACCACGCCCACCGCTCCCCGTGACGTCGTTG
GCTCAGTTATGTCAGACAGGAAATCTCACCATCCCACAATGATTGACAGCTCTCACAGGGAATC
CCGCCTCCGCTGGGACCAATTGACATCACGGACAGGAATACCCGCCCCTGTGGCCCTGATGGGC
AGGTCCTGCCTGGCTCCCATCCTCCATCTCTGACATAAATGCTGTCTCTACAAAAAAAAAAAAA
AAAAA

hide sequence

RefSeq Acc Id:

XM_017599372 ⟹ XP_017454861

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	113,219 - 118,244 (-)	NCBI
mRatBN7.2	14	98,089 - 103,253 (-)	NCBI
Rnor_6.0	14	1,462,292 - 1,466,727 (+)	NCBI

Sequence:

show sequence

CTCAGGGGTTTCCCAACCCAAAGATGAGGAAGTGGGAGCAAGGGACACAGGACGCTGCCCAGGC
CATCTCAGGCATCCCCCTGCCTCAGTTGGGCCATGAGCATCATTCCCCTGCCTCAGCTCCTCGC
CCTGCTCTGCTGCTGCGGACTTGCTGCTGCTACTCAGGGCCCCACAGACCCGTCCACGCCCCCT
AACCTGGGCCTCGCCCACTTCCACAACCTGACCTTCGACCCCGGGACCTGGACACTGAGCTGGG
CCTGTGGCGGCCATGATGGGGCAGTGATGTCGTGCACGGTGATTGACCAGGAGGCAGGGATCCG
GCGCAGAGTGCGGTCCCGGGGCTGCCGCTGCCGGTTTCAGCCAATGGAGTTACACCGCGGGGTC
GACCTGGAGGTTGCGGGGGACAAAGGCCATGCCCAAGTCCATCAGACTCTGCGCTTCGAGAATG
AAGGTGCCCCAGGCTCCGGGGCAGAGAACCTGACCTGTGAGATCCTTGCTGCCCACTTCCTGTG
CTGTTATTGGGCGGTGGGGCCGGCTGCACCCGATGACATCAGATACTCACTGCGCGTGCTCAAC
GCCACTGGTCATGAGGTCGCCAGCTGCTCCGCTGCCCCCGGAACCCCACCCACGCGTTGCCAGG
CTGATGATCTCACACATCTGCCCCGCCTCGCATACATCGTCGTCACTGGGCAGAGCCGGACGGG
GCTGGTGCGGTTCCTGGATGCCGTGGTCAACACCAAGGGCATTGAGCGCCTGGGTCCCCCAGAT
AACGTCTCTGCCTCCTGTAACTTCTCCCACTGCACCATCACCTGGGCTCCGCCCCCTACCTGGG
CGCCTATGACGGAACAGGATTTCCGCTTTGAGATCGAGTGGAAGTCCTGCCCACCCCTTTCTTC
CTCCACTCAGAAGGCGGAGCCCAGCAGCATTGCCCAGAAGGTGGTTATCGCAGGGCGCGAGGAC
AACGCCTTCGCCTTCCCCAGCCCCGCCCCCCGTGGCCGCCTCTGGGTCAGAGTTCGTGCAGGGG
ACACACGCAGTGATCGGTGGAGCGACTGGAGCCCCGCCCTGGAGCTCGGCTCGGAGGCCACAAC
CCCGCCGCGGGCCCTGGTGTGGCGGCGTCGAGCTGTGCAGCCCTGCTGTGTGCGCTGGCACTGG
GGCGGCCTGCAGAGGTGAGG

hide sequence

RefSeq Acc Id:

XM_039092399 ⟹ XP_038948327

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	113,219 - 118,244 (-)	NCBI
mRatBN7.2	14	98,089 - 103,253 (-)	NCBI

RefSeq Acc Id:

XM_063273578 ⟹ XP_063129648

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	113,219 - 118,252 (-)	NCBI

RefSeq Acc Id:

XM_063273579 ⟹ XP_063129649

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	113,219 - 118,247 (-)	NCBI

RefSeq Acc Id:

XM_063273580 ⟹ XP_063129650

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	113,219 - 118,808 (-)	NCBI

RefSeq Acc Id:

XM_063273581 ⟹ XP_063129651

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	113,219 - 118,251 (-)	NCBI

RefSeq Acc Id:

XM_063273582 ⟹ XP_063129652

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	113,219 - 118,252 (-)	NCBI

RefSeq Acc Id:

XM_063273583 ⟹ XP_063129653

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	14	113,219 - 118,250 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001032749	(Get FASTA)	NCBI Sequence Viewer
	XP_017454861	(Get FASTA)	NCBI Sequence Viewer
	XP_038948327	(Get FASTA)	NCBI Sequence Viewer
	XP_063129648	(Get FASTA)	NCBI Sequence Viewer
	XP_063129649	(Get FASTA)	NCBI Sequence Viewer
	XP_063129650	(Get FASTA)	NCBI Sequence Viewer
	XP_063129651	(Get FASTA)	NCBI Sequence Viewer
	XP_063129652	(Get FASTA)	NCBI Sequence Viewer
	XP_063129653	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	CAF31640	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000064492
	ENSRNOP00000064492.3
	ENSRNOP00000075442
	ENSRNOP00000075442.2
	ENSRNOP00000097127.1

RefSeq Acc Id:	NP_001032749 ⟸ NM_001037660
- Peptide Label:	precursor
- UniProtKB:	Q701L2 (UniProtKB/TrEMBL), M0R536 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSIIPLPQLLALLCCCGLAAATQGPTDPSTPPNLGLAHFHNLTFDPGTWTLSWACGGHDGAVMS CTVIDQEAGIRRRVRSRGCRCRFQPMELHRGVDLEVAGDKGHAQVHQTLRFENEGAPGSGAENL TCEILAAHFLCCYWAVGPAAPDDIRYSLRVLNATGHEVASCSAAPGTPPTRCQADDLTHLPRLA YIVVTGQSRTGLVRFLDAVVNTKGIERLGPPDNVSASCNFSHCTITWAPPPTWAPMTEQDFRFE IEWKKAEPSSIAQKVVIAGREDNAFAFPSPAPRGRLWVRVRAGDTRSDRWSDWSPALELGSEAT TPPRALVLAASSCAALLCALALGAACRRLALSRRLLPPIPGIRDRVSDDERVNSETLRKDLLRP hide sequence

RefSeq Acc Id:	XP_017454861 ⟸ XM_017599372
- Peptide Label:	isoform X3
- UniProtKB:	A0A0G2KAL6 (UniProtKB/TrEMBL), M0R536 (UniProtKB/TrEMBL)
- Sequence:	show sequence MSIIPLPQLLALLCCCGLAAATQGPTDPSTPPNLGLAHFHNLTFDPGTWTLSWACGGHDGAVMS CTVIDQEAGIRRRVRSRGCRCRFQPMELHRGVDLEVAGDKGHAQVHQTLRFENEGAPGSGAENL TCEILAAHFLCCYWAVGPAAPDDIRYSLRVLNATGHEVASCSAAPGTPPTRCQADDLTHLPRLA YIVVTGQSRTGLVRFLDAVVNTKGIERLGPPDNVSASCNFSHCTITWAPPPTWAPMTEQDFRFE IEWKSCPPLSSSTQKAEPSSIAQKVVIAGREDNAFAFPSPAPRGRLWVRVRAGDTRSDRWSDWS PALELGSEATTPPRALVWRRRAVQPCCVRWHWGGLQR hide sequence

RefSeq Acc Id:

ENSRNOP00000064492 ⟸ ENSRNOT00000070834

RefSeq Acc Id:

ENSRNOP00000075442 ⟸ ENSRNOT00000077243

RefSeq Acc Id:	XP_038948327 ⟸ XM_039092399
- Peptide Label:	isoform X8

RefSeq Acc Id:

ENSRNOP00000097127 ⟸ ENSRNOT00000106970

RefSeq Acc Id:	XP_063129650 ⟸ XM_063273580
- Peptide Label:	isoform X4
- UniProtKB:	Q701L2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063129652 ⟸ XM_063273582
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063129648 ⟸ XM_063273578
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063129651 ⟸ XM_063273581
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063129653 ⟸ XM_063273583
- Peptide Label:	isoform X7

RefSeq Acc Id:	XP_063129649 ⟸ XM_063273579
- Peptide Label:	isoform X2

Protein Domains

Fibronectin type-III

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-M0R536-F1-model_v2	AlphaFold	M0R536	1-382	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699139

Promoter ID:

EPDNEW_R9661

Type:

multiple initiation site

Name:

Csf2ra_1

Description:

colony stimulating factor 2 receptor alpha subunit

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	14	1,462,331 - 1,462,391	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1594330	AgrOrtholog
BioCyc Gene	G2FUF-16717	BioCyc
Ensembl Genes	ENSRNOG00000049782	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000070834	ENTREZGENE
	ENSRNOT00000070834.3	UniProtKB/TrEMBL
	ENSRNOT00000077243.2	UniProtKB/TrEMBL
	ENSRNOT00000106970.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	Fibronectin_type3	UniProtKB/TrEMBL
	FN3_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
	IL3Ra_N	UniProtKB/TrEMBL
	IL6_recept-bd	UniProtKB/TrEMBL
	Short_hematopoietin_rcpt_2_CS	UniProtKB/TrEMBL
KEGG Report	rno:652957	UniProtKB/TrEMBL
NCBI Gene	652957	ENTREZGENE
PANTHER	CYTOKINE RECEPTOR	UniProtKB/TrEMBL
	ERYTHROPOIETIN RECEPTOR	UniProtKB/TrEMBL
	PTHR23037:SF35	UniProtKB/TrEMBL
Pfam	IL3Ra_N	UniProtKB/TrEMBL
	IL6Ra-bind	UniProtKB/TrEMBL
PhenoGen	Csf2ra	PhenoGen
PROSITE	FN3	UniProtKB/TrEMBL
	HEMATOPO_REC_S_F2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000049782	RatGTEx
Superfamily-SCOP	FN_III-like	UniProtKB/TrEMBL
UniProt	A0A0G2KAL6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6B5C9_RAT	UniProtKB/TrEMBL
	M0R536	ENTREZGENE, UniProtKB/TrEMBL
	Q701L2	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-12-06	Csf2ra	colony stimulating factor 2 receptor subunit alpha	Csf2ra	colony stimulating factor 2 receptor alpha subunit	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2016-01-20	Csf2ra	colony stimulating factor 2 receptor alpha subunit	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-08-01	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)	Csf2ra	granulocyte-macrophage colony stimulating receptor alpha	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-20	Csf2ra	granulocyte-macrophage colony stimulating receptor alpha			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - CTD

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Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)

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Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Imported Annotations - KEGG (archival)

Imported Annotations - PID (archival)