Gene: RT1-Db1 (RT1 class II, locus Db1) Rattus norvegicus
Symbol: RT1-Db1
Name: RT1 class II, locus Db1
Description: ENCODES a protein that exhibits MHC class II protein complex binding (ortholog); peptide antigen binding (ortholog); INVOLVED IN antigen processing and presentation of exogenous peptide antigen via MHC class II (ortholog); detection of bacterium (ortholog); humoral immune response mediated by circulating immunoglobulin (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; allograft rejection pathway; antigen processing and presentation pathway; ASSOCIATED WITH Actinic Prurigo (ortholog); Addison Disease (ortholog); Alzheimer Disease (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular exosome (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 3H-1,2-dithiole-3-thione; amitriptyline
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Db1; MGC105710; MHC class II RT1D beta1 chain antigen; rano class II histocompatibility antigen, D-1 beta chain; RT1 class II histocompatibility antigen, D-1 beta chain; RT1 class II, locus Db1 (mapped); RT1-D beta; RT1-Db; RT1-Db1_mapped; RT1-Db1n
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.0204,087,621 - 4,097,190+NCBI
Rat Cytogenetic Map20p12 NCBI
RGSC Genome Assembly v5.0206,167,759 - 6,177,328+NCBI
RGSC Genome Assembly v3.4204,671,489 - 4,681,058-NCBI
Rat Celera Assembly206,150,824 - 6,160,393-NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
QTLs in Region (RGSC Genome Assembly v5.0)


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on RT1-Db1
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1593282
Created: 2006-11-20
Species: Rattus norvegicus
Last Modified: 2015-03-18
Status: ACTIVE