Tead2 (TEA domain transcription factor 2) - Rat Genome Database

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Gene: Tead2 (TEA domain transcription factor 2) Rattus norvegicus
Analyze
Symbol: Tead2
Name: TEA domain transcription factor 2
RGD ID: 1593252
Description: Predicted to enable several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; disordered domain specific binding activity; and transcription coactivator binding activity. Predicted to be involved in several processes, including embryonic organ development; hippo signaling; and regulation of DNA-templated transcription. Predicted to act upstream of or within several processes, including cellular response to retinoic acid; positive regulation of transcription by RNA polymerase II; and tube morphogenesis. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of TEAD-YAP complex. Orthologous to human TEAD2 (TEA domain transcription factor 2); INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: embryonic TEA domain containing factor; TEA domain family member 2; TEA domain family member 2 (mapped); Tead2_mapped; transcriptional enhancer factor TEF-4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,838,795 - 104,855,635 (+)NCBIGRCr8
mRatBN7.2195,702,366 - 95,719,186 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,703,005 - 95,719,186 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,088,694 - 101,104,579 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,561,364 - 109,577,250 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,851,763 - 102,867,647 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,213,782 - 101,230,483 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,213,788 - 101,230,477 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,278,640 - 102,295,457 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,694,077 - 95,709,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera189,961,576 - 89,977,460 (+)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. DNA methylation may restrict but does not determine differential gene expression at the Sgy/Tead2 locus during mouse development. Kaneko KJ, etal., Mol Cell Biol 2004 Mar;24(5):1968-82.
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7629195   PMID:9502435   PMID:12477932   PMID:14736747   PMID:16207754   PMID:17868131   PMID:18332127   PMID:18579750   PMID:19324877   PMID:20368466   PMID:20596238   PMID:21385842  


Genomics

Comparative Map Data
Tead2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,838,795 - 104,855,635 (+)NCBIGRCr8
mRatBN7.2195,702,366 - 95,719,186 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,703,005 - 95,719,186 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,088,694 - 101,104,579 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,561,364 - 109,577,250 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,851,763 - 102,867,647 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,213,782 - 101,230,483 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,213,788 - 101,230,477 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,278,640 - 102,295,457 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,694,077 - 95,709,961 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera189,961,576 - 89,977,460 (+)NCBICelera
Cytogenetic Map1q22NCBI
TEAD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,340,595 - 49,362,416 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,340,595 - 49,362,457 (-)EnsemblGRCh38hg38GRCh38
GRCh371949,843,852 - 49,865,673 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,535,664 - 54,557,526 (-)NCBINCBI36Build 36hg18NCBI36
Build 341954,535,668 - 54,557,526NCBI
Celera1946,710,704 - 46,732,570 (-)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,220,662 - 46,242,282 (-)NCBIHuRef
CHM1_11949,845,698 - 49,867,693 (-)NCBICHM1_1
T2T-CHM13v2.01952,338,023 - 52,359,872 (-)NCBIT2T-CHM13v2.0
Tead2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,865,216 - 44,882,892 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,865,177 - 44,883,068 (+)EnsemblGRCm39 Ensembl
GRCm38745,215,792 - 45,233,468 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,215,753 - 45,233,644 (+)EnsemblGRCm38mm10GRCm38
MGSCv37752,471,123 - 52,488,989 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36745,083,795 - 45,101,661 (+)NCBIMGSCv36mm8
Celera740,671,641 - 40,689,485 (+)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.19NCBI
Tead2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,450,706 - 1,465,947 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,450,706 - 1,465,947 (+)NCBIChiLan1.0ChiLan1.0
TEAD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,458,521 - 55,480,453 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,379,408 - 57,400,615 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,355,283 - 46,377,224 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,279,551 - 55,301,219 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1955,280,287 - 55,299,341 (-)Ensemblpanpan1.1panPan2
TEAD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,115,014 - 107,130,563 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,115,094 - 107,131,038 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,698,311 - 106,713,862 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,635,334 - 107,650,877 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,635,410 - 107,650,874 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,308,241 - 107,323,786 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,950,420 - 106,965,951 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,791,541 - 107,807,097 (+)NCBIUU_Cfam_GSD_1.0
Tead2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,624,790 - 21,639,467 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,242,974 - 3,255,856 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,242,815 - 3,257,649 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TEAD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl654,448,191 - 54,462,210 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1654,448,183 - 54,462,325 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TEAD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,522,684 - 42,545,581 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,523,405 - 42,543,402 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,444,674 - 22,468,522 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tead2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248324,821,697 - 4,837,257 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tead2
34 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:269
Count of miRNA genes:168
Interacting mature miRNAs:196
Transcripts:ENSRNOT00000028086
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)194494440117601394Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat

Markers in Region
RH128432  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2195,718,880 - 95,719,085 (+)MAPPERmRatBN7.2
mRatBN7.28122,576,421 - 122,576,626 (+)MAPPERmRatBN7.2
Rnor_6.08132,007,713 - 132,007,917NCBIRnor6.0
Rnor_6.01101,230,178 - 101,230,382NCBIRnor6.0
Rnor_5.01102,295,152 - 102,295,356UniSTSRnor5.0
Rnor_5.08131,162,510 - 131,162,714UniSTSRnor5.0
RGSC_v3.4195,709,662 - 95,709,866UniSTSRGSC3.4
RGSC_v3.48127,666,927 - 127,667,131UniSTSRGSC3.4
Celera189,977,161 - 89,977,365UniSTS
Cytogenetic Map8q32UniSTS
Cytogenetic Map1q22UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 26 6 6 1 6 51 21 33 1
Low 3 17 51 35 18 35 6 8 23 14 8 10 6
Below cutoff 2 3 2

Sequence


RefSeq Acc Id: ENSRNOT00000028086   ⟹   ENSRNOP00000028086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,703,294 - 95,719,180 (+)Ensembl
Rnor_6.0 Ensembl1101,214,593 - 101,230,477 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000090838   ⟹   ENSRNOP00000072360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl195,703,005 - 95,719,186 (+)Ensembl
Rnor_6.0 Ensembl1101,213,788 - 101,230,477 (+)Ensembl
RefSeq Acc Id: NM_001107512   ⟹   NP_001100982
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,839,745 - 104,855,629 (+)NCBI
mRatBN7.2195,703,294 - 95,719,180 (+)NCBI
Rnor_6.01101,214,593 - 101,230,477 (+)NCBI
Rnor_5.01102,278,640 - 102,295,457 (+)NCBI
RGSC_v3.4195,694,077 - 95,709,961 (+)RGD
Celera189,961,576 - 89,977,460 (+)RGD
Sequence:
RefSeq Acc Id: XM_006229069   ⟹   XP_006229131
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,838,795 - 104,855,635 (+)NCBI
mRatBN7.2195,702,366 - 95,719,186 (+)NCBI
Rnor_6.01101,213,782 - 101,230,483 (+)NCBI
Rnor_5.01102,278,640 - 102,295,457 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063262026   ⟹   XP_063118096
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,838,910 - 104,855,635 (+)NCBI
RefSeq Acc Id: XM_063262027   ⟹   XP_063118097
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,838,907 - 104,855,635 (+)NCBI
RefSeq Acc Id: XM_063262029   ⟹   XP_063118099
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81104,838,795 - 104,854,309 (+)NCBI
RefSeq Acc Id: NP_001100982   ⟸   NM_001107512
- UniProtKB: B5DF69 (UniProtKB/TrEMBL),   A6JAZ6 (UniProtKB/TrEMBL),   A0A0G2K2S9 (UniProtKB/TrEMBL),   F7FJJ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006229131   ⟸   XM_006229069
- Peptide Label: isoform X1
- UniProtKB: B5DF69 (UniProtKB/TrEMBL),   A6JAZ6 (UniProtKB/TrEMBL),   A0A0G2K2S9 (UniProtKB/TrEMBL),   F7FJJ2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000028086   ⟸   ENSRNOT00000028086
RefSeq Acc Id: ENSRNOP00000072360   ⟸   ENSRNOT00000090838
RefSeq Acc Id: XP_063118099   ⟸   XM_063262029
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063118097   ⟸   XM_063262027
- Peptide Label: isoform X1
- UniProtKB: A6JAZ6 (UniProtKB/TrEMBL),   B5DF69 (UniProtKB/TrEMBL),   F7FJJ2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118096   ⟸   XM_063262026
- Peptide Label: isoform X1
- UniProtKB: A6JAZ6 (UniProtKB/TrEMBL),   B5DF69 (UniProtKB/TrEMBL),   F7FJJ2 (UniProtKB/TrEMBL)
Protein Domains
TEA   YAP binding

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DF69-F1-model_v2 AlphaFold B5DF69 1-445 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690041
Promoter ID:EPDNEW_R557
Type:multiple initiation site
Name:Tead2_1
Description:TEA domain transcription factor 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01101,213,806 - 101,213,866EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1593252 AgrOrtholog
BioCyc Gene G2FUF-59702 BioCyc
Ensembl Genes ENSRNOG00000020695 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000028086 ENTREZGENE
  ENSRNOT00000028086.5 UniProtKB/TrEMBL
  ENSRNOT00000090838.2 UniProtKB/TrEMBL
Gene3D-CATH 2.70.50.80 UniProtKB/TrEMBL
  6.10.20.40 UniProtKB/TrEMBL
InterPro TEA/ATTS UniProtKB/TrEMBL
  TEA/ATTS_sf UniProtKB/TrEMBL
  TEF UniProtKB/TrEMBL
  YBD UniProtKB/TrEMBL
KEGG Report rno:308582 UniProtKB/TrEMBL
NCBI Gene 308582 ENTREZGENE
PANTHER TRANSCRIPTIONAL ENHANCER FACTOR TEF RELATED UniProtKB/TrEMBL
  TRANSCRIPTIONAL ENHANCER FACTOR TEF-4 UniProtKB/TrEMBL
Pfam TEA UniProtKB/TrEMBL
  YBD UniProtKB/TrEMBL
PhenoGen Tead2 PhenoGen
PIRSF TEF UniProtKB/TrEMBL
PRINTS TEADOMAIN UniProtKB/TrEMBL
PROSITE TEA_1 UniProtKB/TrEMBL
  TEA_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020695 RatGTEx
SMART TEA UniProtKB/TrEMBL
UniProt A0A0G2K2S9 ENTREZGENE, UniProtKB/TrEMBL
  A6JAZ6 ENTREZGENE, UniProtKB/TrEMBL
  A6JAZ7_RAT UniProtKB/TrEMBL
  A6JAZ8_RAT UniProtKB/TrEMBL
  A6JAZ9_RAT UniProtKB/TrEMBL
  A6JB00_RAT UniProtKB/TrEMBL
  B5DF69 ENTREZGENE
  F7FJJ2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary B5DF69 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-21 Tead2  TEA domain transcription factor 2  Tead2  TEA domain family member 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-04-13   TEA domain family member 2  Tead2  TEA domain family member 2 (mapped)  Name updated 737654 APPROVED
2007-04-12 Tead2  TEA domain family member 2 (mapped)  Tead2_mapped  TEA domain family member 2 (mapped)  Data merged from RGD:3840 737654 APPROVED
2006-11-20 Tead2  TEA domain family member 2 (mapped)      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-11-17 Tead2_mapped  TEA domain family member 2 (mapped)      Symbol and Name updated 1556543 APPROVED
2001-07-23 Tead2  Embryonic TEA domain containing factor      Name withdrawn 67952 WITHDRAWN
2001-07-23 Tead2  TEA domain family member 2      Name updated to reflect Human and Mouse nomenclature 67952 APPROVED