Phactr4 (phosphatase and actin regulator 4) - Rat Genome Database

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Gene: Phactr4 (phosphatase and actin regulator 4) Rattus norvegicus
Analyze
Symbol: Phactr4
Name: phosphatase and actin regulator 4
RGD ID: 1592823
Description: Predicted to enable actin binding activity; protein phosphatase 1 binding activity; and protein phosphatase activator activity. Predicted to be involved in several processes, including enteric nervous system development; morphogenesis of embryonic epithelium; and negative regulation of integrin-mediated signaling pathway. Predicted to be located in lamellipodium. Orthologous to human PHACTR4 (phosphatase and actin regulator 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC682920; similar to phosphatase and actin regulator 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85149,828,716 - 149,904,955 (-)NCBIGRCr8
mRatBN7.25144,549,350 - 144,621,259 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5144,549,363 - 144,620,865 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.05150,533,895 - 150,609,423 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5150,546,430 - 150,609,352 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05154,201,108 - 154,271,789 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5142,979,831 - 143,050,378 (-)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
lamellipodium  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:17609112   PMID:22215812  


Genomics

Comparative Map Data
Phactr4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85149,828,716 - 149,904,955 (-)NCBIGRCr8
mRatBN7.25144,549,350 - 144,621,259 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5144,549,363 - 144,620,865 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.05150,533,895 - 150,609,423 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5150,546,430 - 150,609,352 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05154,201,108 - 154,271,789 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5142,979,831 - 143,050,378 (-)NCBICelera
Cytogenetic Map5q36NCBI
PHACTR4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38128,369,740 - 28,500,364 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl128,369,582 - 28,500,364 (+)EnsemblGRCh38hg38GRCh38
GRCh37128,696,251 - 28,826,876 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36128,568,680 - 28,699,468 (+)NCBINCBI36Build 36hg18NCBI36
Build 34128,627,660 - 28,647,435NCBI
Celera127,091,773 - 27,222,657 (+)NCBICelera
Cytogenetic Map1p35.3NCBI
HuRef126,949,696 - 27,080,627 (+)NCBIHuRef
CHM1_1128,811,550 - 28,942,373 (+)NCBICHM1_1
T2T-CHM13v2.0128,211,573 - 28,342,320 (+)NCBIT2T-CHM13v2.0
Phactr4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394132,083,233 - 132,149,765 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4132,083,234 - 132,149,800 (-)EnsemblGRCm39 Ensembl
GRCm384132,355,922 - 132,422,446 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4132,355,923 - 132,422,489 (-)EnsemblGRCm38mm10GRCm38
MGSCv374131,911,838 - 131,978,361 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364131,628,054 - 131,694,483 (-)NCBIMGSCv36mm8
Celera4130,516,722 - 130,583,141 (-)NCBICelera
Cytogenetic Map4D2.3NCBI
cM Map465.24NCBI
Phactr4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554527,532,966 - 7,596,546 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554527,505,647 - 7,593,302 (+)NCBIChiLan1.0ChiLan1.0
PHACTR4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21198,345,636 - 198,479,465 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11197,465,156 - 197,596,412 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0127,634,440 - 27,768,139 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1128,668,122 - 28,801,282 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl128,741,081 - 28,794,870 (+)Ensemblpanpan1.1panPan2
PHACTR4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1271,982,524 - 72,079,916 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl271,984,730 - 72,080,194 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha268,559,009 - 68,657,357 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0272,541,480 - 72,639,931 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl272,541,565 - 72,640,194 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1269,369,674 - 69,467,793 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0270,377,748 - 70,477,442 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0271,375,761 - 71,474,306 (-)NCBIUU_Cfam_GSD_1.0
Phactr4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505846,692,983 - 46,788,352 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647412,517,765 - 12,614,968 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647412,517,800 - 12,613,170 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHACTR4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl685,412,134 - 85,528,715 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1685,411,993 - 85,529,441 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2679,256,482 - 79,343,715 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PHACTR4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120104,303,966 - 104,435,342 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl20104,302,429 - 104,367,831 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603312,051,064 - 12,198,195 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phactr4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476412,203,622 - 12,306,974 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476412,203,854 - 12,306,879 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Phactr4
333 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:91
Count of miRNA genes:45
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000072101, ENSRNOT00000074374
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
631505Bp103Blood pressure QTL 1033.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5132717196165560427Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1300119Bp180Blood pressure QTL 1803.82arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5144358090157869054Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
631263Cm24Cardiac mass QTL 243.5heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)5143799107158428037Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
2302369Scl60Serum cholesterol level QTL 603.13blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)5143608201161165651Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
2313096Bmd78Bone mineral density QTL 783.10.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)5144377876161317411Rat

Markers in Region
BF403294  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25144,574,162 - 144,574,326 (+)MAPPERmRatBN7.2
Rnor_6.05150,562,055 - 150,562,218NCBIRnor6.0
Rnor_5.05154,226,732 - 154,226,895UniSTSRnor5.0
Celera5143,004,648 - 143,004,811UniSTS
RH 3.4 Map5965.3UniSTS
RH138093  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25144,550,862 - 144,551,028 (+)MAPPERmRatBN7.2
Rnor_6.05150,535,408 - 150,535,573NCBIRnor6.0
Rnor_5.05154,202,621 - 154,202,786UniSTSRnor5.0
RGSC_v3.41156,817,862 - 56,818,027UniSTSRGSC3.4
Celera5142,981,344 - 142,981,509UniSTS
RH 3.4 Map5977.2UniSTS
Cytogenetic Map11q21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 10 8 6 6 35 31 30 11
Low 1 33 49 35 19 35 8 11 39 4 11 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001427181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001427182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_001063709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006225570 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006225572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776103 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008776104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017593929 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039111276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063288416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000074374   ⟹   ENSRNOP00000065513
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5144,559,444 - 144,583,947 (-)Ensembl
Rnor_6.0 Ensembl5150,546,430 - 150,609,352 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105203   ⟹   ENSRNOP00000094116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5144,549,363 - 144,595,840 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107632   ⟹   ENSRNOP00000095468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5144,549,363 - 144,620,865 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111943   ⟹   ENSRNOP00000093257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5144,549,363 - 144,620,865 (-)Ensembl
RefSeq Acc Id: NM_001427181   ⟹   NP_001414110
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,833,361 - 149,904,917 (-)NCBI
RefSeq Acc Id: NM_001427182   ⟹   NP_001414111
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,833,361 - 149,904,917 (-)NCBI
RefSeq Acc Id: XM_039111271   ⟹   XP_038967199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,828,716 - 149,904,951 (-)NCBI
mRatBN7.25144,549,350 - 144,621,063 (-)NCBI
RefSeq Acc Id: XM_039111273   ⟹   XP_038967201
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,828,716 - 149,879,978 (-)NCBI
mRatBN7.25144,549,350 - 144,596,202 (-)NCBI
RefSeq Acc Id: XM_039111275   ⟹   XP_038967203
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,828,716 - 149,904,955 (-)NCBI
mRatBN7.25144,549,350 - 144,621,259 (-)NCBI
RefSeq Acc Id: XM_039111276   ⟹   XP_038967204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,828,716 - 149,904,951 (-)NCBI
mRatBN7.25144,549,350 - 144,621,068 (-)NCBI
RefSeq Acc Id: XM_063288411   ⟹   XP_063144481
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,828,716 - 149,904,951 (-)NCBI
RefSeq Acc Id: XM_063288413   ⟹   XP_063144483
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,828,716 - 149,904,955 (-)NCBI
RefSeq Acc Id: XM_063288414   ⟹   XP_063144484
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,828,716 - 149,904,951 (-)NCBI
RefSeq Acc Id: XM_063288415   ⟹   XP_063144485
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,828,716 - 149,879,976 (-)NCBI
RefSeq Acc Id: XM_063288416   ⟹   XP_063144486
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85149,828,716 - 149,904,955 (-)NCBI
RefSeq Acc Id: ENSRNOP00000065513   ⟸   ENSRNOT00000074374
RefSeq Acc Id: XP_038967203   ⟸   XM_039111275
- Peptide Label: isoform X2
- UniProtKB: M0R7T1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038967204   ⟸   XM_039111276
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038967199   ⟸   XM_039111271
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038967201   ⟸   XM_039111273
- Peptide Label: isoform X5
- UniProtKB: M0R7T1 (UniProtKB/TrEMBL),   A0A8I6AZ06 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000093257   ⟸   ENSRNOT00000111943
RefSeq Acc Id: ENSRNOP00000095468   ⟸   ENSRNOT00000107632
RefSeq Acc Id: ENSRNOP00000094116   ⟸   ENSRNOT00000105203
RefSeq Acc Id: XP_063144486   ⟸   XM_063288416
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063144483   ⟸   XM_063288413
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063144484   ⟸   XM_063288414
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063144481   ⟸   XM_063288411
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063144485   ⟸   XM_063288415
- Peptide Label: isoform X8
RefSeq Acc Id: NP_001414111   ⟸   NM_001427182
- Peptide Label: isoform 2
- UniProtKB: A0A8I6AQY6 (UniProtKB/TrEMBL),   M0R7T1 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001414110   ⟸   NM_001427181
- Peptide Label: isoform 1
- UniProtKB: M0R7T1 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R7T1-F1-model_v2 AlphaFold M0R7T1 1-681 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694106
Promoter ID:EPDNEW_R4620
Type:multiple initiation site
Name:Phactr4_1
Description:phosphatase and actin regulator 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05150,609,272 - 150,609,332EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1592823 AgrOrtholog
BioCyc Gene G2FUF-39689 BioCyc
Ensembl Genes ENSRNOG00000046922 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074374.4 UniProtKB/TrEMBL
  ENSRNOT00000105203.1 UniProtKB/TrEMBL
  ENSRNOT00000107632.1 UniProtKB/TrEMBL
  ENSRNOT00000111943.1 UniProtKB/TrEMBL
Gene3D-CATH 6.10.140.1750 UniProtKB/TrEMBL
  6.10.140.2130 UniProtKB/TrEMBL
InterPro RPEL_repeat UniProtKB/TrEMBL
NCBI Gene 682920 ENTREZGENE
PANTHER PHOSPHATASE AND ACTIN REGULATOR PHACTR UniProtKB/TrEMBL
  PTHR12751:SF4 UniProtKB/TrEMBL
Pfam RPEL UniProtKB/TrEMBL
PhenoGen Phactr4 PhenoGen
PROSITE RPEL UniProtKB/TrEMBL
RatGTEx ENSRNOG00000046922 RatGTEx
SMART RPEL UniProtKB/TrEMBL
UniProt A0A8I6AJP4_RAT UniProtKB/TrEMBL
  A0A8I6AQY6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AZ06 ENTREZGENE, UniProtKB/TrEMBL
  M0R7T1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-13 Phactr4  phosphatase and actin regulator 4  LOC682920  similar to phosphatase and actin regulator 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC682920  similar to phosphatase and actin regulator 4      Symbol and Name status set to provisional 70820 PROVISIONAL