Rufy2 (RUN and FYVE domain containing 2) - Rat Genome Database

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Gene: Rufy2 (RUN and FYVE domain containing 2) Rattus norvegicus
Analyze
Symbol: Rufy2
Name: RUN and FYVE domain containing 2
RGD ID: 1592188
Description: Predicted to enable SH3 domain binding activity. Predicted to be active in cytoplasm. Orthologous to human RUFY2 (RUN and FYVE domain containing 2); INTERACTS WITH acrylamide; bisphenol A; rotenone.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC100910755; LOC361837; LOC690777; RUN and FYVE domain-containing 2; RUN and FYVE domain-containing protein 2; RUN and FYVE domain-containing protein 2-like; similar to RUN and FYVE domain-containing 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82025,566,950 - 25,657,937 (-)NCBIGRCr8
mRatBN7.22025,626,958 - 25,658,157 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2025,621,999 - 25,658,186 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2026,322,309 - 26,351,609 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02025,675,339 - 25,704,636 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02026,261,363 - 26,290,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02027,219,729 - 27,250,006 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2027,220,707 - 27,247,309 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2027,181,195 - 27,208,041 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02029,060,267 - 29,090,619 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42025,320,749 - 25,350,160 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12025,333,674 - 25,363,932 (+)NCBI
Celera2026,924,589 - 26,951,233 (-)NCBICelera
Cytogenetic Map20q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11877430  


Genomics

Comparative Map Data
Rufy2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82025,566,950 - 25,657,937 (-)NCBIGRCr8
mRatBN7.22025,626,958 - 25,658,157 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2025,621,999 - 25,658,186 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2026,322,309 - 26,351,609 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02025,675,339 - 25,704,636 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02026,261,363 - 26,290,687 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02027,219,729 - 27,250,006 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2027,220,707 - 27,247,309 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl2027,181,195 - 27,208,041 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02029,060,267 - 29,090,619 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42025,320,749 - 25,350,160 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12025,333,674 - 25,363,932 (+)NCBI
Celera2026,924,589 - 26,951,233 (-)NCBICelera
Cytogenetic Map20q11NCBI
RUFY2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381068,341,112 - 68,407,277 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1068,341,107 - 68,407,294 (-)EnsemblGRCh38hg38GRCh38
GRCh371070,100,869 - 70,167,034 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361069,773,281 - 69,837,057 (-)NCBINCBI36Build 36hg18NCBI36
Build 341069,770,869 - 69,834,608NCBI
Celera1063,377,878 - 63,442,409 (-)NCBICelera
Cytogenetic Map10q21.3NCBI
HuRef1064,101,126 - 64,167,005 (-)NCBIHuRef
CHM1_11070,382,655 - 70,448,824 (-)NCBICHM1_1
T2T-CHM13v2.01069,210,323 - 69,276,503 (-)NCBIT2T-CHM13v2.0
Rufy2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391062,815,947 - 62,852,988 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1062,816,002 - 62,852,989 (+)EnsemblGRCm39 Ensembl
GRCm381062,980,174 - 63,017,209 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1062,980,223 - 63,017,210 (+)EnsemblGRCm38mm10GRCm38
MGSCv371062,442,971 - 62,481,490 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361062,375,680 - 62,407,118 (+)NCBIMGSCv36mm8
Celera1064,081,547 - 64,120,066 (+)NCBICelera
Cytogenetic Map10B4NCBI
cM Map1032.51NCBI
Rufy2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542520,632,271 - 20,658,610 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542520,632,271 - 20,658,582 (-)NCBIChiLan1.0ChiLan1.0
RUFY2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2880,506,744 - 80,570,684 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11080,512,063 - 80,576,003 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01064,827,663 - 64,891,632 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11067,137,480 - 67,200,421 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1067,137,592 - 67,200,421 (-)Ensemblpanpan1.1panPan2
RUFY2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1419,570,153 - 19,622,037 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl419,572,121 - 19,621,905 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha419,702,525 - 19,754,450 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0419,840,339 - 19,892,528 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl419,840,339 - 19,892,499 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1419,722,465 - 19,774,279 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0419,944,610 - 19,996,602 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0420,287,888 - 20,339,883 (-)NCBIUU_Cfam_GSD_1.0
Rufy2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721361,398,165 - 61,441,108 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365219,891,657 - 9,933,731 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365219,891,697 - 9,934,407 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RUFY2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1471,498,651 - 71,547,311 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11471,497,232 - 71,547,737 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21477,559,558 - 77,606,344 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RUFY2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1962,993,151 - 63,050,274 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl962,993,856 - 63,049,981 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604823,755,974 - 23,817,396 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rufy2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247542,709,727 - 2,743,436 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rufy2
26 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:51
Count of miRNA genes:47
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000037409
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
4889870Pur30Proteinuria QTL 30190.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20804241029322208Rat
7411652Foco24Food consumption QTL 240.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)201175751554435887Rat
9590092Insglur9Insulin/glucose ratio QTL 918.380.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)201175751554435887Rat
4889610Pancm3Pancreatic morphology QTL 33.750.001pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)201761783247606836Rat
2317880Alcrsp25Alcohol response QTL 252.3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)201769755054435887Rat
2303626Vencon10Ventilatory control QTL 100.001respiration trait (VT:0001943)respiration rate (CMO:0000289)201919072154435887Rat
2303578Gluco50Glucose level QTL 502blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)202510672254435887Rat
2303587Bw93Body weight QTL 9313body mass (VT:0001259)body weight (CMO:0000012)202510672254435887Rat
2300188Bmd68Bone mineral density QTL 686.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)202510672254435887Rat
1331747Hrtrt16Heart rate QTL 163.163heart pumping trait (VT:2000009)heart rate (CMO:0000002)202520973454435887Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

circulatory system musculoskeletal system nervous system
High
Medium
Low
Below cutoff 1 1 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001168586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601779 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099101 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279536 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279538 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279545 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279547 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279548 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001842438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000037409   ⟹   ENSRNOP00000035701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2025,628,826 - 25,655,501 (-)Ensembl
Rnor_6.0 Ensembl2027,220,707 - 27,247,309 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000084720   ⟹   ENSRNOP00000073001
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2025,623,841 - 25,658,164 (-)Ensembl
Rnor_6.0 Ensembl2027,181,195 - 27,208,041 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111186   ⟹   ENSRNOP00000089257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2025,621,999 - 25,658,186 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112698   ⟹   ENSRNOP00000081901
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2025,621,999 - 25,658,168 (-)Ensembl
RefSeq Acc Id: NM_001168586   ⟹   NP_001162058
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,627,518 - 25,656,844 (-)NCBI
mRatBN7.22025,628,826 - 25,658,157 (-)NCBI
Rnor_6.02027,220,679 - 27,249,976 (-)NCBI
Rnor_5.02029,060,267 - 29,090,619 (-)NCBI
RGSC_v3.42025,320,749 - 25,350,160 (+)RGD
Celera2026,924,589 - 26,951,233 (-)RGD
Sequence:
RefSeq Acc Id: XM_039099096   ⟹   XP_038955024
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,566,950 - 25,657,920 (-)NCBI
mRatBN7.22025,626,958 - 25,658,035 (-)NCBI
RefSeq Acc Id: XM_039099101   ⟹   XP_038955029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,634,615 - 25,657,926 (-)NCBI
mRatBN7.22025,636,574 - 25,658,076 (-)NCBI
RefSeq Acc Id: XM_039099102   ⟹   XP_038955030
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,634,615 - 25,657,925 (-)NCBI
mRatBN7.22025,635,808 - 25,658,076 (-)NCBI
RefSeq Acc Id: XM_063279536   ⟹   XP_063135606
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,566,950 - 25,657,920 (-)NCBI
RefSeq Acc Id: XM_063279537   ⟹   XP_063135607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,566,950 - 25,657,920 (-)NCBI
RefSeq Acc Id: XM_063279538   ⟹   XP_063135608
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,566,950 - 25,657,920 (-)NCBI
RefSeq Acc Id: XM_063279539   ⟹   XP_063135609
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,627,913 - 25,657,927 (-)NCBI
RefSeq Acc Id: XM_063279540   ⟹   XP_063135610
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,566,950 - 25,656,913 (-)NCBI
RefSeq Acc Id: XM_063279541   ⟹   XP_063135611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,627,913 - 25,657,928 (-)NCBI
RefSeq Acc Id: XM_063279542   ⟹   XP_063135612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,627,913 - 25,657,929 (-)NCBI
RefSeq Acc Id: XM_063279543   ⟹   XP_063135613
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,632,741 - 25,657,927 (-)NCBI
RefSeq Acc Id: XM_063279544   ⟹   XP_063135614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,634,615 - 25,657,937 (-)NCBI
RefSeq Acc Id: XM_063279545   ⟹   XP_063135615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,634,615 - 25,656,913 (-)NCBI
RefSeq Acc Id: XM_063279546   ⟹   XP_063135616
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,634,615 - 25,656,913 (-)NCBI
RefSeq Acc Id: XM_063279547   ⟹   XP_063135617
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,634,615 - 25,656,913 (-)NCBI
RefSeq Acc Id: XM_063279548   ⟹   XP_063135618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82025,634,615 - 25,656,913 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001162058   ⟸   NM_001168586
- UniProtKB: A6JL02 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000035701   ⟸   ENSRNOT00000037409
RefSeq Acc Id: XP_038955024   ⟸   XM_039099096
- Peptide Label: isoform X1
- UniProtKB: A6JL02 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955030   ⟸   XM_039099102
- Peptide Label: isoform X7
RefSeq Acc Id: XP_038955029   ⟸   XM_039099101
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000073001   ⟸   ENSRNOT00000084720
RefSeq Acc Id: ENSRNOP00000081901   ⟸   ENSRNOT00000112698
RefSeq Acc Id: ENSRNOP00000089257   ⟸   ENSRNOT00000111186
RefSeq Acc Id: XP_063135608   ⟸   XM_063279538
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063135606   ⟸   XM_063279536
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063135607   ⟸   XM_063279537
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063135610   ⟸   XM_063279540
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063135612   ⟸   XM_063279542
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063135611   ⟸   XM_063279541
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063135609   ⟸   XM_063279539
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063135613   ⟸   XM_063279543
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063135614   ⟸   XM_063279544
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063135615   ⟸   XM_063279545
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063135617   ⟸   XM_063279547
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063135618   ⟸   XM_063279548
- Peptide Label: isoform X12
RefSeq Acc Id: XP_063135616   ⟸   XM_063279546
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZTG8 (UniProtKB/TrEMBL)
Protein Domains
FYVE-type   RUN

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZSW9-F1-model_v2 AlphaFold D3ZSW9 1-605 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1592188 AgrOrtholog
BioCyc Gene G2FUF-3809 BioCyc
Ensembl Genes ENSRNOG00000000390 Ensembl
  ENSRNOG00000059663 Ensembl
  ENSRNOG00000065563 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000037409.7 UniProtKB/TrEMBL
  ENSRNOT00000084720 ENTREZGENE
  ENSRNOT00000084720.2 UniProtKB/TrEMBL
  ENSRNOT00000111186.1 UniProtKB/TrEMBL
  ENSRNOT00000112698.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.170 UniProtKB/TrEMBL
  1.20.58.900 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro RUFY1-3 UniProtKB/TrEMBL
  Run UniProtKB/TrEMBL
  Run_dom_sf UniProtKB/TrEMBL
  RUN_RUFY2 UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene 690777 ENTREZGENE
PANTHER RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN UniProtKB/TrEMBL
Pfam FYVE UniProtKB/TrEMBL
  RUN UniProtKB/TrEMBL
PhenoGen Rufy2 PhenoGen
PROSITE RUN UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000390 RatGTEx
  ENSRNOG00000059663 RatGTEx
  ENSRNOG00000065563 RatGTEx
SMART FYVE UniProtKB/TrEMBL
  RUN UniProtKB/TrEMBL
Superfamily-SCOP SSF140741 UniProtKB/TrEMBL
  SSF57903 UniProtKB/TrEMBL
UniProt A0A0G2K4D6_RAT UniProtKB/TrEMBL
  A0A8I5ZTG8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GHY0_RAT UniProtKB/TrEMBL
  A6JL02 ENTREZGENE, UniProtKB/TrEMBL
  D3ZSW9_RAT UniProtKB/TrEMBL
UniProt Secondary D4A6B6 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Rufy2  RUN and FYVE domain containing 2  LOC100910755  RUN and FYVE domain-containing protein 2-like  Data merged from RGD:6497270 737654 PROVISIONAL
2013-05-24 Rufy2  RUN and FYVE domain containing 2  LOC687911  similar to RUN and FYVE domain-containing 2  Data merged from RGD:1594937 1643240 APPROVED
2012-07-05 LOC100910755  RUN and FYVE domain-containing protein 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2010-05-21 LOC690777  similar to RUN and FYVE domain-containing 2  Rufy2  RUN and FYVE domain-containing 2  Data merged from RGD:1304564 737654 APPROVED
2010-05-21 Rufy2  RUN and FYVE domain containing 2  LOC690777  similar to RUN and FYVE domain-containing 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Rufy2  RUN and FYVE domain-containing 2   Rufy2_predicted  RUN and FYVE domain-containing 2 (predicted)  'predicted' is removed 2292626 APPROVED
2006-11-20 LOC690777  similar to RUN and FYVE domain-containing 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-20 LOC687911  similar to RUN and FYVE domain-containing 2      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-12 Rufy2_predicted  RUN and FYVE domain-containing 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED