Gene: Gba (glucosylceramidase beta) Rattus norvegicus
Analyze
Symbol: Gba
Name: glucosylceramidase beta
Description: ENCODES a protein that exhibits glucosylceramidase activity; hydrolase activity (ortholog); receptor binding (ortholog); INVOLVED IN beta-glucoside catabolic process; regulation of water loss via skin; response to dexamethasone; PARTICIPATES IN Fabry disease pathway; Gaucher disease pathway; globoid cell leukodystrophy disease pathway; ASSOCIATED WITH autosomal recessive juvenile Parkinson disease 2 (ortholog); Dementia (ortholog); dementia (ortholog); FOUND IN lysosome; extracellular exosome (ortholog); extracellular space (ortholog); INTERACTS WITH bisphenol A; finasteride; gentamycin
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glucocerebrosidase; glucosidase, beta, acid; glucosylceramidase; LOC684536; MGC188451; similar to Glucosylceramidase precursor (Beta-glucocerebrosidase) (Acid beta-glucosidase) (D-glucosyl-N-acylsphingosine glucohydrolase)
Orthologs:
Homo sapiens (human) : GBA (glucosylceramidase beta)  HGNC
Mus musculus (house mouse) : Gba (glucosidase, beta, acid)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Gba (glucosylceramidase beta)
Canis lupus familiaris (dog) : GBA (glucosylceramidase beta)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gba (glucosylceramidase beta)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02188,511,781 - 188,522,602 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02207,931,042 - 207,937,062 (+)NCBIRnor5.0rn5Rnor5.0
Celera2168,551,737 - 168,557,757 (+)NCBI
Cytogenetic Map2q34NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Gba
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1589149
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2017-08-01
Status: ACTIVE