Gene: Gba (glucosidase, beta, acid) Rattus norvegicus
Symbol: Gba
Name: glucosidase, beta, acid
Description: ENCODES a protein that exhibits glucosylceramidase activity; receptor binding (ortholog); INVOLVED IN regulation of water loss via skin; response to estrogen; response to glucocorticoid; PARTICIPATES IN sphingolipid metabolic pathway; ASSOCIATED WITH Gaucher Disease (ortholog); Gaucher Disease, Perinatal Lethal (ortholog); Gaucher Disease, Type Iiic (ortholog); FOUND IN extracellular vesicular exosome (ortholog); lysosomal lumen (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 9-cis-retinoic acid (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glucocerebrosidase; glucosylceramidase; LOC684536; MGC188451; similar to Glucosylceramidase precursor (Beta-glucocerebrosidase) (Acid beta-glucosidase) (D-glucosyl-N-acylsphingosine glucohydrolase)
Orthologs:
Latest Assembly: RGSC Genome Assembly v5.0
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.02188,516,582 - 188,522,602+NCBI
Rat Cytogenetic Map2q34 NCBI
RGSC Genome Assembly v5.02207,931,042 - 207,937,062+NCBI
Rat Celera Assembly2168,551,737 - 168,557,757+NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Gba
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1589149
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2014-12-02
Status: ACTIVE