Gene: Gba (glucosylceramidase beta) Rattus norvegicus
Symbol: Gba
Name: glucosylceramidase beta
Description: ENCODES a protein that exhibits glucosylceramidase activity; hydrolase activity (ortholog); receptor binding (ortholog); INVOLVED IN regulation of water loss via skin; response to estrogen; response to glucocorticoid; PARTICIPATES IN Fabry disease pathway; Gaucher disease pathway; globoid cell leukodystrophy disease pathway; ASSOCIATED WITH Gaucher Disease (ortholog); Gaucher Disease, Perinatal Lethal (ortholog); Gaucher Disease, Type Iiic (ortholog); FOUND IN extracellular exosome (ortholog); extracellular space (ortholog); lysosomal lumen (ortholog); INTERACTS WITH bisphenol A; finasteride; 17alpha-ethynylestradiol (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: glucocerebrosidase; glucosidase, beta, acid; glucosylceramidase; glucosylceramidase beta; LOC684536; MGC188451; similar to Glucosylceramidase precursor (Beta-glucocerebrosidase) (Acid beta-glucosidase) (D-glucosyl-N-acylsphingosine glucohydrolase)
Orthologs:
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.02188,516,582 - 188,522,602 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02207,931,042 - 207,937,062 (+)NCBIRnor5.0rn5Rnor5.0
Celera2168,551,737 - 168,557,757 (+)NCBI
Cytogenetic Map2q34NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Gba
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1589149
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2016-05-31
Status: ACTIVE