Gene: Gba (glucosidase, beta, acid) Rattus norvegicus
Symbol: Gba
Name: glucosidase, beta, acid
Description: ENCODES a protein that exhibits glucosylceramidase activity; receptor binding (ortholog); INVOLVED IN regulation of water loss via skin; response to estrogen; response to glucocorticoid; PARTICIPATES IN sphingolipid metabolic pathway; ASSOCIATED WITH Gaucher Disease (ortholog); Gaucher Disease, Perinatal Lethal (ortholog); Gaucher Disease, Type Iiic (ortholog); FOUND IN extracellular vesicular exosome (ortholog); lysosomal lumen (ortholog); lysosomal membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol (ortholog); 2,3,7,8-tetrachlorodibenzodioxine (ortholog); 9-cis-retinoic acid (ortholog)
Type: protein-coding
Also known as: glucocerebrosidase; glucosylceramidase; LOC684536; MGC188451; similar to Glucosylceramidase precursor (Beta-glucocerebrosidase) (Acid beta-glucosidase) (D-glucosyl-N-acylsphingosine glucohydrolase)
Latest Assembly: RGSC Genome Assembly v3.4
RGSC Genome Assembly v6.02188,516,582 - 188,522,602+NCBI
Rat Cytogenetic Map2q34 NCBI
RGSC Genome Assembly v5.02207,931,042 - 207,937,062+NCBI
Rat Celera Assembly2168,551,737 - 168,557,757+NCBI
This feature is not available in GBrowse. This may be because it does not have a position on the current reference assembly, or because it maps to either the mitochondrial (MT) chromosome or an unknown (Un) chromosome.
Browse the genome for the Rat reference assembly: v3.4

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Gba
Entrez Gene
Ensembl Gene
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Vista + UCSC

RGD Object Information
RGD ID: 1589149
Created: 2006-11-19
Species: Rattus norvegicus
Last Modified: 2014-10-14
Status: ACTIVE