Myl6 (myosin light chain 6) - Rat Genome Database

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Gene: Myl6 (myosin light chain 6) Rattus norvegicus
Analyze
Symbol: Myl6
Name: myosin light chain 6
RGD ID: 1589019
Description: Predicted to enable microfilament motor activity. Predicted to be a structural constituent of muscle. Predicted to be involved in muscle filament sliding and skeletal muscle tissue development. Predicted to be located in brush border. Predicted to be part of myosin II complex and unconventional myosin complex. Orthologous to human MYL6 (myosin light chain 6); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 17 kDa myosin light chain; LC17; LOC685867; MGC188345; MLC-3; Myl6l; myosin light chain 3; myosin light chain A3; myosin light chain alkali 3; myosin light polypeptide 6; myosin, light chain 6, alkali, smooth muscle and non-muscle; myosin, light polypeptide 6, alkali, smooth muscle and non-muscle; myosin, light polypeptide 6, alkali, smooth muscle and non-muscle-like; non-muscle myosin alkali light chain; similar to myosin, light polypeptide 6, alkali, smooth muscle and non-muscle; smooth muscle and nonmuscle myosin light chain alkali 6
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,495,301 - 1,498,512 (-)NCBIGRCr8
mRatBN7.27910,764 - 914,062 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7910,774 - 933,791 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,672,717 - 3,675,759 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,548,698 - 5,551,740 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,846,357 - 5,849,400 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,906,137 - 2,909,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,906,137 - 2,909,179 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,880,878 - 2,882,625 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,772,621 - 1,775,663 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7783,878 - 786,920 (-)NCBICelera
Cytogenetic Map7q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(S)-nicotine  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3'-diindolylmethane  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amphetamine  (EXP)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (EXP,ISO)
bleomycin A2  (EXP)
cadmium dichloride  (ISO)
chloropicrin  (ISO)
chrysene  (ISO)
cisplatin  (EXP,ISO)
clothianidin  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dextran sulfate  (ISO)
dibenzo[a,l]pyrene  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
fipronil  (EXP)
folic acid  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
glafenine  (EXP)
indole-3-methanol  (EXP)
isobutanol  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
lead(II) chloride  (ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
menadione  (ISO)
nicotine  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
phenethyl isothiocyanate  (ISO)
phenobarbital  (ISO)
PhIP  (EXP)
SB 431542  (ISO)
selenium atom  (ISO)
sodium fluoride  (ISO)
sunitinib  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function. Hailstones DL and Gunning PW, Mol Cell Biol. 1990 Mar;10(3):1095-104.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7733921   PMID:12477932   PMID:15632090   PMID:16854843   PMID:16953301   PMID:19190083   PMID:19946888   PMID:20458337   PMID:21700703   PMID:22114352   PMID:22871113   PMID:23376485  
PMID:23533145   PMID:23979707   PMID:24625528   PMID:29476059   PMID:35352799  


Genomics

Comparative Map Data
Myl6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,495,301 - 1,498,512 (-)NCBIGRCr8
mRatBN7.27910,764 - 914,062 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7910,774 - 933,791 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx73,672,717 - 3,675,759 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,548,698 - 5,551,740 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,846,357 - 5,849,400 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,906,137 - 2,909,193 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,906,137 - 2,909,179 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.072,880,878 - 2,882,625 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.471,772,621 - 1,775,663 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera7783,878 - 786,920 (-)NCBICelera
Cytogenetic Map7q11NCBI
MYL6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,158,359 - 56,161,579 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,158,346 - 56,163,496 (+)EnsemblGRCh38hg38GRCh38
GRCh371256,552,143 - 56,555,363 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361254,838,367 - 54,841,633 (+)NCBINCBI36Build 36hg18NCBI36
Build 341254,838,412 - 54,841,625NCBI
Celera1256,204,244 - 56,207,510 (+)NCBICelera
Cytogenetic Map12q13.2NCBI
HuRef1253,591,104 - 53,594,425 (+)NCBIHuRef
CHM1_11256,519,428 - 56,522,749 (+)NCBICHM1_1
T2T-CHM13v2.01256,125,971 - 56,129,191 (+)NCBIT2T-CHM13v2.0
Myl6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910128,326,728 - 128,329,755 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10128,326,729 - 128,330,014 (-)EnsemblGRCm39 Ensembl
GRCm3810128,490,859 - 128,493,886 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,490,860 - 128,494,145 (-)EnsemblGRCm38mm10GRCm38
MGSCv3710127,927,917 - 127,930,881 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv3610127,893,810 - 127,896,774 (-)NCBIMGSCv36mm8
Celera10130,882,814 - 130,885,778 (-)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.75NCBI
Myl6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554583,760,695 - 3,763,652 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554583,760,695 - 3,763,652 (+)NCBIChiLan1.0ChiLan1.0
MYL6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21038,170,858 - 38,174,379 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11238,167,626 - 38,171,068 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,754,146 - 32,757,436 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11233,004,923 - 33,008,329 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1233,004,181 - 33,008,329 (-)Ensemblpanpan1.1panPan2
MYL6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110476,944 - 480,122 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10476,989 - 480,827 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha10540,437 - 543,631 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.010485,590 - 488,789 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10481,463 - 489,494 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110463,051 - 466,242 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.010706,139 - 709,321 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.010830,176 - 833,371 (+)NCBIUU_Cfam_GSD_1.0
Myl6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494558,299,887 - 58,303,122 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646567,209 - 570,348 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936646567,112 - 570,348 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYL6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,559,029 - 21,562,413 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1521,559,226 - 21,562,418 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,251,782 - 23,254,969 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYL6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,099,075 - 52,102,205 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666037193,882,099 - 193,885,358 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Myl6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,847,061 - 11,850,084 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462480211,847,061 - 11,850,187 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Myl6
14 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:58
Count of miRNA genes:45
Interacting mature miRNAs:51
Transcripts:ENSRNOT00000071616
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat

Markers in Region
RH132927  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27914,115 - 914,295 (+)MAPPERmRatBN7.2
Rnor_6.072,909,489 - 2,909,668NCBIRnor6.0
Rnor_5.072,882,914 - 2,883,093UniSTSRnor5.0
RGSC_v3.471,775,973 - 1,776,152UniSTSRGSC3.4
Celera7787,230 - 787,409UniSTS
Cytogenetic Map7q11UniSTS
MARC_5817-5818:991939742:3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21229,488,321 - 29,488,621 (+)MAPPERmRatBN7.2
Rnor_6.01233,182,625 - 33,182,924NCBIRnor6.0
Rnor_5.01235,081,483 - 35,081,782UniSTSRnor5.0
Rnor_5.072,881,097 - 2,881,396UniSTSRnor5.0
RGSC_v3.41230,532,503 - 30,532,802UniSTSRGSC3.4
Celera1231,175,080 - 31,175,379UniSTS
Cytogenetic Map12q14UniSTS
Cytogenetic Map7q11UniSTS
Myln  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27910,922 - 912,262 (+)MAPPERmRatBN7.2
Rnor_6.072,906,296 - 2,907,635NCBIRnor6.0
RGSC_v3.471,772,780 - 1,774,119UniSTSRGSC3.4
Celera7784,037 - 785,376UniSTS
Cytogenetic Map7q11UniSTS
Cytogenetic Map13p11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 1 2 2
Medium 2 41 57 41 19 41 8 11 74 35 41 9 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001109484 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765039 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017595113 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039079906 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264267 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264268 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC128207 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC166586 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217952 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222504 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222561 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223129 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228447 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S77858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000082518   ⟹   ENSRNOP00000070200
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7910,779 - 913,769 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000085644   ⟹   ENSRNOP00000069845
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7910,775 - 914,067 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000089074   ⟹   ENSRNOP00000073838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7910,774 - 933,791 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000094248   ⟹   ENSRNOP00000096022
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7910,855 - 913,765 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099810   ⟹   ENSRNOP00000088676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7911,210 - 913,806 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107790   ⟹   ENSRNOP00000080100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl7910,778 - 914,067 (-)Ensembl
RefSeq Acc Id: NM_001109484   ⟹   NP_001102954
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,495,301 - 1,498,343 (-)NCBI
mRatBN7.27910,764 - 913,806 (-)NCBI
Rnor_6.072,906,137 - 2,909,179 (-)NCBI
Rnor_5.072,880,878 - 2,882,625 (-)NCBI
RGSC_v3.471,772,621 - 1,775,663 (-)RGD
Celera7783,878 - 786,920 (-)RGD
Sequence:
RefSeq Acc Id: XM_008765039   ⟹   XP_008763261
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,495,309 - 1,498,512 (-)NCBI
mRatBN7.27910,772 - 914,062 (-)NCBI
Rnor_6.072,906,148 - 2,909,193 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017595113   ⟹   XP_017450602
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,495,309 - 1,498,352 (-)NCBI
mRatBN7.27910,772 - 914,062 (-)NCBI
Rnor_6.072,906,145 - 2,909,153 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039079906   ⟹   XP_038935834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,495,309 - 1,498,512 (-)NCBI
mRatBN7.27910,956 - 914,062 (-)NCBI
RefSeq Acc Id: XM_063264265   ⟹   XP_063120335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,495,309 - 1,498,512 (-)NCBI
RefSeq Acc Id: XM_063264266   ⟹   XP_063120336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,495,309 - 1,498,352 (-)NCBI
RefSeq Acc Id: XM_063264267   ⟹   XP_063120337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,495,309 - 1,497,505 (-)NCBI
RefSeq Acc Id: XM_063264268   ⟹   XP_063120338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,495,309 - 1,498,352 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001102954   ⟸   NM_001109484
- UniProtKB: Q64119 (UniProtKB/Swiss-Prot),   A6KSD7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763261   ⟸   XM_008765039
- Peptide Label: isoform X1
- UniProtKB: Q64119 (UniProtKB/Swiss-Prot),   B2GV99 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017450602   ⟸   XM_017595113
- Peptide Label: isoform X5
- UniProtKB: A6KSD9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_038935834   ⟸   XM_039079906
- Peptide Label: isoform X3
- UniProtKB: Q64119 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: ENSRNOP00000070200   ⟸   ENSRNOT00000082518
RefSeq Acc Id: ENSRNOP00000080100   ⟸   ENSRNOT00000107790
RefSeq Acc Id: ENSRNOP00000088676   ⟸   ENSRNOT00000099810
RefSeq Acc Id: ENSRNOP00000096022   ⟸   ENSRNOT00000094248
RefSeq Acc Id: ENSRNOP00000069845   ⟸   ENSRNOT00000085644
RefSeq Acc Id: ENSRNOP00000073838   ⟸   ENSRNOT00000089074
RefSeq Acc Id: XP_063120335   ⟸   XM_063264265
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063120338   ⟸   XM_063264268
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063120336   ⟸   XM_063264266
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063120337   ⟸   XM_063264267
- Peptide Label: isoform X4
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q64119-F1-model_v2 AlphaFold Q64119 1-151 view protein structure
AF-B2GV99-F1-model_v2 AlphaFold B2GV99 1-152 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694952
Promoter ID:EPDNEW_R5464
Type:initiation region
Name:Myl6_1
Description:myosin light chain 6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.072,909,148 - 2,909,208EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1589019 AgrOrtholog
BioCyc Gene G2FUF-35364 BioCyc
Ensembl Genes ENSRNOG00000054140 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082518.2 UniProtKB/TrEMBL
  ENSRNOT00000085644.2 UniProtKB/TrEMBL
  ENSRNOT00000089074.2 UniProtKB/TrEMBL
  ENSRNOT00000094248.1 UniProtKB/TrEMBL
  ENSRNOT00000099810.1 UniProtKB/TrEMBL
  ENSRNOT00000107790.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7934414 IMAGE-MGC_LOAD
InterPro EF-hand-dom_pair UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:685867 UniProtKB/TrEMBL
MGC_CLONE MGC:188345 IMAGE-MGC_LOAD
NCBI Gene 685867 ENTREZGENE
PANTHER MYOSIN LIGHT CHAIN 1, 3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MYOSIN LIGHT POLYPEPTIDE 6 UniProtKB/Swiss-Prot
  MYOSIN LIGHT POLYPEPTIDE 6 UniProtKB/TrEMBL
  MYOSIN LIGHT POLYPEPTIDE 6 UniProtKB/TrEMBL
PhenoGen Myl6 PhenoGen
PROSITE EF_HAND_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000054140 RatGTEx
SMART EFh UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP EF-hand UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JWE1_RAT UniProtKB/TrEMBL
  A0A0G2JXA9_RAT UniProtKB/TrEMBL
  A0A0G2K6J5_RAT UniProtKB/TrEMBL
  A0A8I6AB85_RAT UniProtKB/TrEMBL
  A0A8I6AUI8_RAT UniProtKB/TrEMBL
  A6KSD7 ENTREZGENE, UniProtKB/TrEMBL
  A6KSD9 ENTREZGENE, UniProtKB/TrEMBL
  A6KSE3_RAT UniProtKB/TrEMBL
  A6KSE4_RAT UniProtKB/TrEMBL
  B2GV99 ENTREZGENE, UniProtKB/TrEMBL
  MYL6_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-10 Myl6  myosin light chain 6  Myl6  myosin, light chain 6, alkali, smooth muscle and non-muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-05 Myl6  myosin, light chain 6, alkali, smooth muscle and non-muscle  LOC685867  similar to myosin, light polypeptide 6, alkali, smooth muscle and non-muscle  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-19 LOC685867  similar to myosin, light polypeptide 6, alkali, smooth muscle and non-muscle      Symbol and Name status set to provisional 70820 PROVISIONAL