Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-catechin | multiple interactions | ISO | SIN3B (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in decreased expression of SIN3B mRNA | CTD | PMID:24763279 | 1,2-dimethylhydrazine | decreases expression | ISO | Sin3b (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SIN3B mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | Sin3b (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of SIN3B mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | Sin3b (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIN3B mRNA | CTD | PMID:17942748 | 17beta-estradiol | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Estradiol results in increased expression of SIN3B mRNA | CTD | PMID:23019147 | 17beta-estradiol | decreases expression | ISO | Sin3b (Mus musculus) | 6480464 | Estradiol results in decreased expression of SIN3B mRNA | CTD | PMID:19484750 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sin3b (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SIN3B mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SIN3B mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Sin3b (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIN3B mRNA | CTD | PMID:17942748 | 2-hydroxypropanoic acid | decreases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SIN3B mRNA | CTD | PMID:30851411 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Sin3b (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of SIN3B mRNA | CTD | PMID:26251327 | 3,4-methylenedioxymethamphetamine | increases methylation | ISO | Sin3b (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased methylation of SIN3B promoter | CTD | PMID:26251327 | 4,4'-sulfonyldiphenol | affects methylation | ISO | Sin3b (Mus musculus) | 6480464 | bisphenol S affects the methylation of SIN3B exon and bisphenol S affects the methylation of SIN3B gene | CTD | PMID:31683443 and PMID:33297965 | 4-vinylcyclohexene dioxide | affects expression | ISO | Sin3b (Mus musculus) | 6480464 | 4-vinyl-1-cyclohexene dioxide affects the expression of SIN3B mRNA | CTD | PMID:20829426 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SIN3B mRNA | CTD | PMID:24780913 and PMID:30047161 | all-trans-retinoic acid | decreases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SIN3B mRNA | CTD | PMID:23724009 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of SIN3B mRNA | CTD | PMID:30047161 | aristolochic acid A | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of SIN3B mRNA | CTD | PMID:33212167 | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of SIN3B gene | CTD | PMID:35440735 | benzo[a]pyrene | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of SIN3B mRNA | CTD | PMID:26238291 | benzo[a]pyrene diol epoxide I | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of SIN3B mRNA | CTD | PMID:30816183 and PMID:34947998 | bisphenol A | increases expression | ISO | Sin3b (Mus musculus) | 6480464 | bisphenol A results in increased expression of SIN3B mRNA | CTD | PMID:33221593 | buspirone | increases expression | EXP | | 6480464 | Buspirone results in increased expression of SIN3B mRNA | CTD | PMID:24136188 | carbon nanotube | increases expression | ISO | Sin3b (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in increased expression of SIN3B mRNA | CTD | PMID:25554681 and PMID:25620056 | CGP 52608 | multiple interactions | ISO | SIN3B (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SIN3B gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Sin3b (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SIN3B mRNA | CTD | PMID:37019170 | ciguatoxin CTX1B | affects expression | ISO | Sin3b (Mus musculus) | 6480464 | Ciguatoxins affects the expression of SIN3B mRNA | CTD | PMID:18353800 | cobalt dichloride | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of SIN3B mRNA | CTD | PMID:19376846 | coumarin | decreases phosphorylation | ISO | SIN3B (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of SIN3B protein | CTD | PMID:35688186 | CU-O LINKAGE | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | cupric oxide results in increased expression of SIN3B mRNA | CTD | PMID:22077320 | cylindrospermopsin | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | cylindrospermopsin results in increased expression of SIN3B mRNA | CTD | PMID:24921660 | dicrotophos | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | dicrotophos results in increased expression of SIN3B mRNA | CTD | PMID:28302478 | elemental selenium | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Selenium results in increased expression of SIN3B mRNA | CTD | PMID:19244175 | Erionite | decreases expression | ISO | Sin3b (Mus musculus) | 6480464 | erionite results in decreased expression of SIN3B mRNA | CTD | PMID:29279043 | ethanol | affects splicing | ISO | Sin3b (Mus musculus) | 6480464 | Ethanol affects the splicing of SIN3B mRNA | CTD | PMID:30319688 | fenthion | decreases expression | ISO | Sin3b (Mus musculus) | 6480464 | Fenthion results in decreased expression of SIN3B mRNA | CTD | PMID:34813904 | folic acid | decreases expression | ISO | Sin3b (Mus musculus) | 6480464 | Folic Acid results in decreased expression of SIN3B mRNA | CTD | PMID:25629700 | FR900359 | affects phosphorylation | ISO | SIN3B (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of SIN3B protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | SIN3B (Homo sapiens) | 6480464 | Fulvestrant promotes the reaction [SIN3B protein binds to CCNA2 promoter] more ... | CTD | PMID:21367843 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of SIN3B mRNA | CTD | PMID:22061828 and PMID:33387578 | hydroquinone O-beta-D-glucopyranoside | decreases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Arbutin results in decreased expression of SIN3B mRNA | CTD | PMID:17103032 | kojic acid | decreases expression | ISO | SIN3B (Homo sapiens) | 6480464 | kojic acid results in decreased expression of SIN3B mRNA | CTD | PMID:16595896 | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of SIN3B mRNA | CTD | PMID:24136188 | methapyrilene | increases expression | EXP | | 6480464 | Methapyrilene results in increased expression of SIN3B mRNA | CTD | PMID:30467583 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of SIN3B mRNA | CTD | PMID:30047161 | methoxychlor | affects expression | ISO | Sin3b (Mus musculus) | 6480464 | Methoxychlor affects the expression of SIN3B mRNA | CTD | PMID:20829426 | N-(6-acetamidohexyl)acetamide | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | hexamethylene bisacetamide results in increased expression of SIN3B protein | CTD | PMID:17569113 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of SIN3B mRNA | CTD | PMID:24136188 | ozone | multiple interactions | ISO | SIN3B (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of SIN3B mRNA | CTD | PMID:35430440 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of SIN3B mRNA | CTD | PMID:33387578 | potassium dichromate | decreases expression | ISO | Sin3b (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of SIN3B mRNA | CTD | PMID:23608068 | rac-lactic acid | decreases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of SIN3B mRNA | CTD | PMID:30851411 | selenium atom | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Selenium results in increased expression of SIN3B mRNA | CTD | PMID:19244175 | sodium arsenate | increases expression | ISO | Sin3b (Mus musculus) | 6480464 | sodium arsenate results in increased expression of SIN3B mRNA | CTD | PMID:30953684 | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of SIN3B mRNA | CTD | PMID:30047161 | sunitinib | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Sunitinib results in increased expression of SIN3B mRNA | CTD | PMID:31533062 | tamoxifen | affects expression | ISO | Sin3b (Mus musculus) | 6480464 | Tamoxifen affects the expression of SIN3B mRNA | CTD | PMID:17555576 | temozolomide | increases expression | ISO | SIN3B (Homo sapiens) | 6480464 | Temozolomide results in increased expression of SIN3B mRNA | CTD | PMID:31758290 | titanium dioxide | decreases expression | ISO | Sin3b (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of SIN3B mRNA | CTD | PMID:27760801 | triptonide | increases expression | ISO | Sin3b (Mus musculus) | 6480464 | triptonide results in increased expression of SIN3B mRNA | CTD | PMID:33045310 | tungsten | increases expression | ISO | Sin3b (Mus musculus) | 6480464 | Tungsten results in increased expression of SIN3B mRNA | CTD | PMID:30912803 | valproic acid | affects expression | ISO | Sin3b (Mus musculus) | 6480464 | Valproic Acid affects the expression of SIN3B mRNA | CTD | PMID:17963808 | valproic acid | increases methylation | ISO | SIN3B (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of SIN3B gene | CTD | PMID:29154799 | valproic acid | affects expression | ISO | SIN3B (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SIN3B mRNA | CTD | PMID:25979313 | |