Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | monilethrix | | ISO | KRT83 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | monilethrix | | ISO | KRT83 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | The hairless phenotype of the Hirosaki hairless rat is due to the deletion of an 80-kb genomic DNA containing five basic keratin genes. | Nanashima N, etal., J Biol Chem. 2008 Jun 13;283(24):16868-75. Epub 2008 Apr 16. |
3. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
4. | GOA pipeline | RGD automated data pipeline |
5. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
6. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
7. | Comprehensive gene review and curation | RGD comprehensive gene curation |
Krt87 (Rattus norvegicus - Norway rat) |
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KRT83 (Homo sapiens - human) |
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KRT87P (Homo sapiens - human) |
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Krt87 (Mus musculus - house mouse) |
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LOC100523123 (Sus scrofa - pig) |
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Variants in Krt87
46 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
alimentary part of gastrointestinal system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | ||||||||||||
Medium | ||||||||||||
Low | 2 | 2 | 4 | 2 | ||||||||
Below cutoff | 1 | 9 | 4 | 8 | 4 | 2 | 2 | 8 | 2 | 15 | 4 | 2 |
RefSeq Acc Id: | ENSRNOT00000031257 ⟹ ENSRNOP00000029805 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000077286 ⟹ ENSRNOP00000069234 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000098871 ⟹ ENSRNOP00000090562 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000108728 ⟹ ENSRNOP00000081533 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001101675 ⟹ NP_001095145 | ||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063264250 ⟹ XP_063120320 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001095145 | (Get FASTA) | NCBI Sequence Viewer |
XP_063120320 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | BAF75713 | (Get FASTA) | NCBI Sequence Viewer |
Ensembl Protein | ENSRNOP00000029805 | ||
ENSRNOP00000029805.3 | |||
ENSRNOP00000069234.1 | |||
ENSRNOP00000090562.1 |
RefSeq Acc Id: | NP_001095145 ⟸ NM_001101675 |
- UniProtKB: | A7M746 (UniProtKB/TrEMBL), D4ABK6 (UniProtKB/TrEMBL), A0A8I6A9T4 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000029805 ⟸ ENSRNOT00000031257 |
RefSeq Acc Id: | ENSRNOP00000069234 ⟸ ENSRNOT00000077286 |
RefSeq Acc Id: | ENSRNOP00000090562 ⟸ ENSRNOT00000098871 |
RefSeq Acc Id: | ENSRNOP00000081533 ⟸ ENSRNOT00000108728 |
RefSeq Acc Id: | XP_063120320 ⟸ XM_063264250 |
- Peptide Label: | isoform X1 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-A7M746-F1-model_v2 | AlphaFold | A7M746 | 1-495 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13695671 | ||||||||
Promoter ID: | EPDNEW_R6196 | ||||||||
Type: | single initiation site | ||||||||
Name: | Krt83_1 | ||||||||
Description: | keratin 83 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1583565 | AgrOrtholog |
BioCyc Gene | G2FUF-31985 | BioCyc |
Ensembl Genes | ENSRNOG00000032859 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000031257 | ENTREZGENE |
ENSRNOT00000031257.5 | UniProtKB/TrEMBL | |
ENSRNOT00000077286.2 | UniProtKB/TrEMBL | |
ENSRNOT00000098871.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 1.20.5.170 | UniProtKB/TrEMBL |
Single helix bin | UniProtKB/TrEMBL | |
Vasodilator-stimulated phosphoprotein | UniProtKB/TrEMBL | |
InterPro | IF_rod_dom | UniProtKB/TrEMBL |
Intermediate_filament_CS | UniProtKB/TrEMBL | |
Keratin_2_head | UniProtKB/TrEMBL | |
Keratin_II | UniProtKB/TrEMBL | |
KEGG Report | rno:681126 | UniProtKB/TrEMBL |
NCBI Gene | 681126 | ENTREZGENE |
PANTHER | GATA-TYPE DOMAIN-CONTAINING PROTEIN | UniProtKB/TrEMBL |
KERATIN, TYPE II CUTICULAR 87 | UniProtKB/TrEMBL | |
Pfam | Filament | UniProtKB/TrEMBL |
Keratin_2_head | UniProtKB/TrEMBL | |
PharmGKB | KRT83 | RGD |
PhenoGen | Krt87 | PhenoGen |
PRINTS | TYPE2KERATIN | UniProtKB/TrEMBL |
PROSITE | IF_ROD_2 | UniProtKB/TrEMBL |
PS00226 | UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000032859 | RatGTEx |
SMART | Filament | UniProtKB/TrEMBL |
Superfamily-SCOP | Intermediate filament protein, coiled coil region | UniProtKB/TrEMBL |
UniProt | A0A0G2JUU5_RAT | UniProtKB/TrEMBL |
A0A8I6A9T4 | ENTREZGENE, UniProtKB/TrEMBL | |
A7M746 | ENTREZGENE, UniProtKB/TrEMBL | |
D4ABK6 | ENTREZGENE | |
UniProt Secondary | D4ABK6 | UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2022-10-21 | Krt87 | keratin 87 | Krt83 | keratin 83 | Name and Symbol changed | 629549 | APPROVED |
2016-03-16 | Krt83 | keratin 83 | Krt83 | keratin 83, type II | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2015-01-28 | Krt83 | keratin 83, type II | Krt83 | keratin 83 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-09-24 | Krt83 | keratin 83 | LOC681126 | similar to keratin complex 2, basic, gene 25 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2006-11-19 | LOC681126 | similar to keratin complex 2, basic, gene 25 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |