Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | TCP11L1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TCP11L1 mRNA | CTD | PMID:22079256 | (1->4)-beta-D-glucan | multiple interactions | ISO | Tcp11l1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TCP11L1 mRNA | CTD | PMID:36331819 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of TCP11L1 mRNA | CTD | PMID:29097150 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TCP11L1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TCP11L1 mRNA | CTD | PMID:33387578 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tcp11l1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of TCP11L1 mRNA | CTD | PMID:21570461 | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of TCP11L1 protein | CTD | PMID:34915118 | 4,4'-sulfonyldiphenol | decreases methylation | ISO | TCP11L1 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of TCP11L1 gene | CTD | PMID:31601247 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of TCP11L1 mRNA | CTD | PMID:31881176 | aflatoxin B1 | affects expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of TCP11L1 protein | CTD | PMID:20106945 | aflatoxin B1 | increases methylation | ISO | TCP11L1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of TCP11L1 gene | CTD | PMID:27153756 | aflatoxin B1 | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of TCP11L1 mRNA | CTD | PMID:27153756 | atrazine | decreases expression | EXP | | 6480464 | Atrazine results in decreased expression of TCP11L1 mRNA | CTD | PMID:36841081 | beauvericin | multiple interactions | ISO | TCP11L1 (Homo sapiens) | 6480464 | [beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein | CTD | PMID:32407736 | benzo[a]pyrene | increases mutagenesis | ISO | TCP11L1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TCP11L1 gene | CTD | PMID:25435355 | benzo[a]pyrene | decreases methylation | ISO | TCP11L1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of TCP11L1 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of TCP11L1 mRNA | CTD | PMID:21632981 and PMID:26238291 | benzo[a]pyrene diol epoxide I | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of TCP11L1 mRNA | CTD | PMID:25181051 | bisphenol A | increases expression | ISO | Tcp11l1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TCP11L1 mRNA | CTD | PMID:35598803 | bisphenol A | decreases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of TCP11L1 protein | CTD | PMID:33376534 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TCP11L1 mRNA | CTD | PMID:34947998 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TCP11L1 mRNA | CTD | PMID:29097150 | CGP 52608 | multiple interactions | ISO | TCP11L1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TCP11L1 gene] | CTD | PMID:28238834 | chlordecone | decreases expression | ISO | Tcp11l1 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of TCP11L1 mRNA | CTD | PMID:29980752 | choline | multiple interactions | ISO | Tcp11l1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TCP11L1 mRNA | CTD | PMID:20938992 | cobalt dichloride | decreases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of TCP11L1 mRNA | CTD | PMID:19320972 | coumarin | decreases phosphorylation | ISO | TCP11L1 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of TCP11L1 protein | CTD | PMID:35688186 | crocidolite asbestos | increases expression | ISO | Tcp11l1 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in increased expression of TCP11L1 mRNA | CTD | PMID:29279043 | cyclosporin A | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of TCP11L1 mRNA | CTD | PMID:25562108 | dorsomorphin | multiple interactions | ISO | TCP11L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TCP11L1 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of TCP11L1 mRNA | CTD | PMID:29803840 | enniatin | multiple interactions | ISO | TCP11L1 (Homo sapiens) | 6480464 | [beauvericin co-treated with enniatins] results in decreased expression of TCP11L1 protein | CTD | PMID:32407736 | enzyme inhibitor | multiple interactions | ISO | TCP11L1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of TCP11L1 protein | CTD | PMID:23301498 | epoxiconazole | decreases expression | ISO | Tcp11l1 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of TCP11L1 mRNA | CTD | PMID:35436446 | ethanol | increases expression | ISO | Tcp11l1 (Mus musculus) | 6480464 | Ethanol results in increased expression of TCP11L1 mRNA | CTD | PMID:30319688 | ethyl methanesulfonate | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of TCP11L1 mRNA | CTD | PMID:23649840 | fenvalerate | increases expression | EXP | | 6480464 | fenvalerate results in increased expression of TCP11L1 mRNA | CTD | PMID:30307764 | folic acid | multiple interactions | ISO | Tcp11l1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TCP11L1 mRNA | CTD | PMID:20938992 | fragrance | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Perfume results in increased expression of TCP11L1 mRNA | CTD | PMID:24768652 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of TCP11L1 mRNA | CTD | PMID:25539665 | glyphosate | increases expression | ISO | Tcp11l1 (Mus musculus) | 6480464 | Glyphosate results in increased expression of TCP11L1 mRNA | CTD | PMID:35897073 | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of TCP11L1 mRNA | CTD | PMID:22129741 | L-methionine | multiple interactions | ISO | Tcp11l1 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of TCP11L1 mRNA | CTD | PMID:20938992 | methyl methanesulfonate | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of TCP11L1 mRNA | CTD | PMID:23649840 | methylmercury chloride | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TCP11L1 mRNA | CTD | PMID:28001369 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of TCP11L1 mRNA | CTD | PMID:22129741 | paracetamol | affects expression | ISO | Tcp11l1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TCP11L1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of TCP11L1 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of TCP11L1 mRNA | CTD | PMID:22230336 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Tcp11l1 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of TCP11L1 mRNA | CTD | PMID:36331819 | potassium chromate | decreases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of TCP11L1 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | TCP11L1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of TCP11L1 mRNA | CTD | PMID:22079256 | quercetin | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Quercetin results in increased expression of TCP11L1 mRNA | CTD | PMID:21632981 | SB 431542 | multiple interactions | ISO | TCP11L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TCP11L1 mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of TCP11L1 mRNA | CTD | PMID:25351596 | sodium arsenite | decreases expression | ISO | Tcp11l1 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of TCP11L1 mRNA | CTD | PMID:37682722 | sulforaphane | decreases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | sulforaphane results in decreased expression of TCP11L1 mRNA | CTD | PMID:31838189 | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of TCP11L1 mRNA | CTD | PMID:31150632 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of TCP11L1 mRNA | CTD | PMID:23411599 | valproic acid | increases expression | ISO | TCP11L1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TCP11L1 mRNA | CTD | PMID:23179753 and PMID:26272509 | valproic acid | multiple interactions | ISO | TCP11L1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of TCP11L1 mRNA | CTD | PMID:27188386 | valproic acid | affects splicing | EXP | | 6480464 | Valproic Acid affects the splicing of TCP11L1 mRNA | CTD | PMID:29427782 | |