Gene: Lrrk2 (leucine-rich repeat kinase 2) Rattus norvegicus
Symbol: Lrrk2
Name: leucine-rich repeat kinase 2
Description: ENCODES a protein that exhibits actin binding (ortholog); clathrin binding (ortholog); glycoprotein binding (ortholog); INVOLVED IN cellular response to organic cyclic compound; activation of MAPK activity (ortholog); activation of MAPKK activity (ortholog); PARTICIPATES IN Parkinson disease pathway; ASSOCIATED WITH Amyotrophic Lateral Sclerosis (ortholog); Arthritis, Rheumatoid (ortholog); Colitis (ortholog); FOUND IN axon; cytoplasm; dendrite; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene; copper(2+) sulfate (ortholog)
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: leucine-rich repeat serine/threonine-protein kinase 2
Orthologs:
Allele / Splice: Lrrk1em1SageLrrk2em1Sage   Lrrk2em1Sage  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
RGSC Genome Assembly v6.07132,857,313 - 133,018,549+NCBI
Rat Cytogenetic Map7q35 NCBI
RGSC Genome Assembly v5.07132,531,591 - 132,694,226+NCBI
RGSC Genome Assembly v3.47130,105,902 - 130,267,747+NCBI
Rat Celera Assembly7119,264,946 - 119,423,875+NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Lrrk2
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 1561168
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2014-10-14
Status: ACTIVE