Gene: Phox2b (paired-like homeobox 2b) Rattus norvegicus
Symbol: Phox2b
Name: paired-like homeobox 2b
Description: ENCODES a protein that exhibits RNA polymerase II core promoter proximal region sequence-specific DNA binding (ortholog); RNA polymerase II regulatory region sequence-specific DNA binding (ortholog); transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding (ortholog); INVOLVED IN autonomic nervous system development (ortholog); brainstem development (ortholog); cell development (ortholog); ASSOCIATED WITH Congenital Central Hypoventilation Syndrome (ortholog); Hirschsprung disease ganglioneuroblastoma (ortholog); Hypoventilation (ortholog); FOUND IN nuclear chromatin (ortholog); nucleus (ortholog); INTERACTS WITH bisphenol A; 2-methylcholine (ortholog); 3,4-methylenedioxymethamphetamine (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: NBPhox; neuroblastoma Phox; paired mesoderm homeobox protein 2B
Latest Assembly: RGSC Genome Assembly v5.0
RGSC Genome Assembly v6.01442,711,438 - 42,718,707+NCBI
Rat Cytogenetic Map14p11 NCBI
RGSC Genome Assembly v5.01442,510,540 - 42,514,526+NCBI
RGSC Genome Assembly v3.41443,675,180 - 43,677,970+NCBI
Rat Celera Assembly1440,219,013 - 40,226,258+NCBI

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Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v5.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
More on Phox2b
Entrez Gene
Ensembl Gene
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 1560582
Created: 2006-02-09
Species: Rattus norvegicus
Last Modified: 2015-10-01
Status: ACTIVE