Yae1l1 (YAE1 maturation factor of ABCE1 like 1) - Rat Genome Database

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Gene: Yae1l1 (YAE1 maturation factor of ABCE1 like 1) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Yae1l1 (Ensembl: LOC500028)
Name: YAE1 maturation factor of ABCE1 like 1 (Ensembl:hypothetical protein LOC500028)
RGD ID: 1560448
Description: Predicted to be located in cytoplasm and nucleus.
Type: protein-coding
RefSeq Status: PREDICTED
Previously known as: hypothetical protein LOC500028; LOC500028; uncharacterized protein LOC500028
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8438,884,039 - 38,884,713 (-)NCBIGRCr8
mRatBN7.2437,917,837 - 37,918,511 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl437,917,837 - 37,918,511 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx442,894,380 - 42,895,054 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0438,820,590 - 38,821,264 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0437,224,104 - 37,224,778 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0435,889,550 - 35,890,224 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl435,889,550 - 35,890,224 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0435,745,595 - 35,746,269 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4434,958,168 - 34,958,842 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera433,400,199 - 33,400,873 (-)NCBICelera
Cytogenetic Map4q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
nucleus  (IEA)

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:14
Count of miRNA genes:14
Interacting mature miRNAs:14
Transcripts:ENSRNOT00000011848
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61415Eae11Experimental allergic encephalomyelitis QTL 112.9nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)4139505420Rat
634323Hc2Hypercalciuria QTL 22.15urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)421079645210796Rat
619616Bp79Blood pressure QTL 790.0292arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4521460278882945Rat
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
2302371Stl22Serum triglyceride level QTL 225.15blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829457114705Rat
1358203Stl19Serum triglyceride level QTL 192.80.002blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521829465958103Rat
631642Stl2Serum triglyceride level QTL 23.3blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)4521917856647776Rat
631209Bw2Body weight QTL24.2retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)4994088544463908Rat
1300141Bp178Blood pressure QTL 178arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)41002490139524530Rat
6478724Anxrr35Anxiety related response QTL 350.00449defecation behavior trait (VT:0010462)defecation measurement (CMO:0000997)41008408955084089Rat
6478766Anxrr47Anxiety related response QTL 470.09637locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)41008408955084089Rat
6478769Anxrr48Anxiety related response QTL 480.02514locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)41008408955084089Rat
8694374Bw155Body weight QTL 1553.390.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)41008408955084089Rat
9590304Scort17Serum corticosterone level QTL 174.960.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)41008408955084089Rat
8552906Pigfal3Plasma insulin-like growth factor 1 level QTL 3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)41008408955084089Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
2303585Bw86Body weight QTL 864body mass (VT:0001259)body weight (CMO:0000012)41467806559678065Rat
2313401Anxrr27Anxiety related response QTL 27aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)41793350862933508Rat
70222Eae2Experimental allergic encephalomyelitis QTL 24.3nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)42133334339505420Rat
1354665Stl10Serum triglyceride level QTL 103.57blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)42133334344463908Rat
61412Pia2Pristane induced arthritis QTL 23.9joint integrity trait (VT:0010548)post-insult time to onset of experimental arthritis (CMO:0001450)42133334362278020Rat
6909122Insul22Insulin level QTL 224.63blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)42690728575585128Rat
6909128Pancm4Pancreatic morphology QTL 411.35pancreas mass (VT:0010144)pancreas wet weight (CMO:0000626)42690728575585128Rat
8655906Rf60Renal function QTL 603.8blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)42949419581006281Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
11530004Niddm71Non-insulin dependent diabetes mellitus QTL 710.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43258419952754138Rat
8655949Rf62Renal function QTL 6222blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)43443011944463908Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
4889511Gluco61Glucose level QTL 614.70.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43717795040869000Rat
2290374Gluco32Glucose level QTL 326.27blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)43717795044463908Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 1 3 20 10 12 10 5 6 7 3 7 6 5
Below cutoff 1 7 6 1 6 1 3 5 4 8 5 5 3

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000011848
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl437,917,837 - 37,918,511 (-)Ensembl
Rnor_6.0 Ensembl435,889,550 - 35,890,224 (-)Ensembl
RefSeq Acc Id: NM_001047954   ⟹   NP_001041419
RefSeq Status: PREDICTED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8438,884,039 - 38,884,713 (-)NCBI
mRatBN7.2437,917,837 - 37,918,511 (-)NCBI
Rnor_6.0435,889,550 - 35,890,224 (-)NCBI
Rnor_5.0435,745,595 - 35,746,269 (-)NCBI
RGSC_v3.4434,958,168 - 34,958,842 (-)RGD
Celera433,400,199 - 33,400,873 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001041419 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAQ96241 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000090167
  ENSRNOP00000090167.1
Reference Protein Sequences
RefSeq Acc Id: NP_001041419   ⟸   NM_001047954
- UniProtKB: Q6TXH1 (UniProtKB/TrEMBL),   A6K997 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Essential protein Yae1 N-terminal

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1560448 AgrOrtholog
BioCyc Gene G2FUF-45649 BioCyc
Ensembl Genes ENSRNOG00000008962 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011848 ENTREZGENE
  ENSRNOT00000011848.4 UniProtKB/TrEMBL
InterPro Essential_protein_Yae1_N UniProtKB/TrEMBL
  Yae1-like UniProtKB/TrEMBL
KEGG Report rno:500028 UniProtKB/TrEMBL
NCBI Gene 500028 ENTREZGENE
PANTHER PROTEIN YAE1 HOMOLOG UniProtKB/TrEMBL
  PTHR18829 UniProtKB/TrEMBL
Pfam Yae1_N UniProtKB/TrEMBL
PhenoGen Yae1l1 PhenoGen
RatGTEx ENSRNOG00000008962 RatGTEx
UniProt A6K997 ENTREZGENE, UniProtKB/TrEMBL
  Q6TXH1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-09-19 Yae1l1  YAE1 maturation factor of ABCE1 like 1  LOC500028  hypothetical protein LOC500028  Symbol and Name Changed 1299863 APPROVED
2006-02-09 LOC500028  hypothetical protein LOC500028      Symbol and Name status set to provisional 70820 PROVISIONAL