Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-alpha-phellandrene | decreases expression | ISO | DCTD (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of DCTD mRNA | CTD | PMID:25075043 | (1->4)-beta-D-glucan | multiple interactions | ISO | Dctd (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of DCTD mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | increases expression | ISO | Dctd (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of DCTD mRNA | CTD | PMID:22206623 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Dctd (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of DCTD mRNA | CTD | PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of DCTD mRNA | CTD | PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Dctd (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of DCTD mRNA | CTD | PMID:21570461 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of DCTD mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Dctd (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of DCTD mRNA | CTD | PMID:18648102 | 4,4'-sulfonyldiphenol | increases expression | ISO | DCTD (Homo sapiens) | 6480464 | bisphenol S results in increased expression of DCTD protein | CTD | PMID:34186270 | 5-aza-2'-deoxycytidine | decreases methylation | ISO | Dctd (Mus musculus) | 6480464 | Decitabine results in decreased methylation of DCTD gene | CTD | PMID:27923600 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of DCTD mRNA | CTD | PMID:24780913 and PMID:30047161 | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of DCTD mRNA | CTD | PMID:31881176 | acrolein | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DCTD mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DCTD mRNA | CTD | PMID:32699268 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of DCTD mRNA | CTD | PMID:25378103 | all-trans-retinoic acid | decreases expression | ISO | DCTD (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of DCTD mRNA | CTD | PMID:33167477 | alpha-phellandrene | decreases expression | ISO | DCTD (Homo sapiens) | 6480464 | alpha phellandrene results in decreased expression of DCTD mRNA | CTD | PMID:25075043 | alpha-pinene | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DCTD mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased oxidation of DCTD mRNA | CTD | PMID:32699268 | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of DCTD mRNA | CTD | PMID:30047161 | amphetamine | decreases expression | EXP | | 6480464 | Amphetamine results in decreased expression of DCTD mRNA | CTD | PMID:30779732 | antimycin A | decreases expression | ISO | DCTD (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of DCTD mRNA | CTD | PMID:33512557 | arsenous acid | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DCTD protein] | CTD | PMID:26598702 | benzo[a]pyrene | decreases expression | ISO | Dctd (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of DCTD mRNA | CTD | PMID:19770486 | bisphenol A | decreases expression | ISO | Dctd (Mus musculus) | 6480464 | bisphenol A results in decreased expression of DCTD mRNA | CTD | PMID:26063408 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of DCTD mRNA | CTD | PMID:30816183 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of DCTD mRNA | CTD | PMID:25181051 | bisphenol F | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of DCTD mRNA | CTD | PMID:28628672 | carbon nanotube | increases expression | ISO | Dctd (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to DCTD gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | ISO | Dctd (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of DCTD mRNA | CTD | PMID:37019170 | choline | multiple interactions | ISO | Dctd (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCTD mRNA | CTD | PMID:20938992 | cobalt dichloride | decreases expression | ISO | DCTD (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of DCTD mRNA | CTD | PMID:19320972 | cyclosporin A | increases expression | ISO | DCTD (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of DCTD mRNA | CTD | PMID:20106945 | deguelin | increases expression | ISO | DCTD (Homo sapiens) | 6480464 | deguelin results in increased expression of DCTD mRNA | CTD | PMID:33512557 | dexamethasone | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of DCTD mRNA | CTD | PMID:28628672 | diarsenic trioxide | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | Arsenic Trioxide inhibits the reaction [4-aminophenylarsenoxide binds to DCTD protein] | CTD | PMID:26598702 | dioxygen | multiple interactions | ISO | Dctd (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of DCTD mRNA | CTD | PMID:30529165 | enzyme inhibitor | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of DCTD protein | CTD | PMID:23301498 | folic acid | multiple interactions | ISO | Dctd (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCTD mRNA | CTD | PMID:20938992 | furan | increases expression | EXP | | 6480464 | furan results in increased expression of DCTD mRNA | CTD | PMID:25539665 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of DCTD mRNA | CTD | PMID:33387578 | glyphosate | increases methylation | EXP | | 6480464 | Glyphosate results in increased methylation of DCTD gene | CTD | PMID:31011160 | indometacin | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of DCTD mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | DCTD (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of DCTD protein | CTD | PMID:32959892 | ketamine | decreases expression | EXP | | 6480464 | Ketamine results in decreased expression of DCTD mRNA | CTD | PMID:20080153 | L-methionine | multiple interactions | ISO | Dctd (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of DCTD mRNA | CTD | PMID:20938992 | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of DCTD mRNA | CTD | PMID:30047161 | ozone | multiple interactions | ISO | DCTD (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased oxidation of DCTD mRNA more ... | CTD | PMID:32699268 | ozone | multiple interactions | ISO | Dctd (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of DCTD mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of DCTD mRNA | CTD | PMID:27106289 and PMID:34911549 | paclitaxel | affects response to substance | ISO | DCTD (Homo sapiens) | 6480464 | DCTD protein affects the susceptibility to Paclitaxel | CTD | PMID:16217747 | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of DCTD mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Dctd (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of DCTD mRNA | CTD | PMID:36331819 | phenobarbital | increases expression | ISO | Dctd (Mus musculus) | 6480464 | Phenobarbital results in increased expression of DCTD mRNA | CTD | PMID:25270620 | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of DCTD mRNA | CTD | PMID:30047161 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of DCTD mRNA | CTD | PMID:19281266 | sunitinib | increases expression | ISO | DCTD (Homo sapiens) | 6480464 | Sunitinib results in increased expression of DCTD mRNA | CTD | PMID:31533062 | temozolomide | decreases expression | ISO | DCTD (Homo sapiens) | 6480464 | Temozolomide results in decreased expression of DCTD mRNA | CTD | PMID:31758290 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of DCTD mRNA | CTD | PMID:23411599 and PMID:34492290 | tolcapone | affects binding | EXP | | 6480464 | tolcapone binds to DCTD protein | CTD | PMID:19783845 | trichostatin A | affects expression | ISO | DCTD (Homo sapiens) | 6480464 | trichostatin A affects the expression of DCTD mRNA | CTD | PMID:28542535 | trimellitic anhydride | increases expression | ISO | Dctd (Mus musculus) | 6480464 | trimellitic anhydride results in increased expression of DCTD mRNA | CTD | PMID:19042947 | triptonide | decreases expression | ISO | Dctd (Mus musculus) | 6480464 | triptonide results in decreased expression of DCTD mRNA | CTD | PMID:33045310 | valproic acid | decreases expression | ISO | DCTD (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of DCTD mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | DCTD (Homo sapiens) | 6480464 | Valproic Acid affects the expression of DCTD mRNA | CTD | PMID:25979313 | |