Nol10 (nucleolar protein 10) - Rat Genome Database

Name: Nol10
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Nol10 (nucleolar protein 10) Rattus norvegicus

Analyze

Symbol:

Nol10

Name:

nucleolar protein 10

RGD ID:

1359447

Description:

Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human NOL10 (nucleolar protein 10); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC313981; similar to hypothetical protein FLJ14075

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	NOL10 (nucleolar protein 10)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Nol10 (nucleolar protein 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Nol10 (nucleolar protein 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	NOL10 (nucleolar protein 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	NOL10 (nucleolar protein 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Nol10 (nucleolar protein 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	NOL10 (nucleolar protein 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	NOL10 (nucleolar protein 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Nol10 (nucleolar protein 10)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	NGRN (neugrin, neurite outgrowth associated)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	NOL10 (nucleolar protein 10)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Nol10 (nucleolar protein 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	nol10 (nucleolar protein 10)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	ENP2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	l(2)34Fd	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	nol-10	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	nol10	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	45,861,773 - 45,954,067 (+)	NCBI		GRCr8
mRatBN7.2	6	40,144,217 - 40,225,353 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	40,144,235 - 40,225,353 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	40,471,633 - 40,552,688 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	40,786,329 - 40,867,385 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	40,219,585 - 40,300,635 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	42,656,661 - 42,745,099 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	42,656,616 - 42,745,098 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	52,376,044 - 52,460,901 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	41,121,421 - 41,202,780 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	41,124,373 - 41,205,732 (+)	NCBI
Celera	6	39,444,624 - 39,525,709 (+)	NCBI		Celera
Cytogenetic Map	6	q16	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

megacolon (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(+)-schisandrin B (EXP)

(-)-alpha-phellandrene (ISO)

17beta-estradiol (EXP,ISO)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

acrolein (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

alpha-phellandrene (ISO)

alpha-pinene (ISO)

aristolochic acid A (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bisphenol A (EXP)

diethylstilbestrol (ISO)

dioxygen (ISO)

doxorubicin (ISO)

erlotinib hydrochloride (ISO)

ethyl methanesulfonate (ISO)

folic acid (ISO)

gentamycin (EXP)

methapyrilene (ISO)

methyl methanesulfonate (ISO)

ozone (ISO)

paracetamol (ISO)

perfluorooctane-1-sulfonic acid (ISO)

resveratrol (ISO)

silicon dioxide (ISO)

sunitinib (ISO)

testosterone (EXP)

tetrachloromethane (EXP,ISO)

thioacetamide (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) (IBA,IEA)

Cellular Component

90S preribosome (IEA)

nucleolus (IBA,IEA,ISO)

small-subunit processome (IBA,IEA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	null	JRS Domain-based curation
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Insights into the evolution of the nucleolus by an analysis of its protein domain repertoire.	Staub E, etal., Bioessays 2004 May;26(5):567-81.
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:15489334	PMID:22658674	PMID:22681889

Genomics

Comparative Map Data

Nol10
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	45,861,773 - 45,954,067 (+)	NCBI		GRCr8
mRatBN7.2	6	40,144,217 - 40,225,353 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	40,144,235 - 40,225,353 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	40,471,633 - 40,552,688 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	40,786,329 - 40,867,385 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	40,219,585 - 40,300,635 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	42,656,661 - 42,745,099 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	42,656,616 - 42,745,098 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	52,376,044 - 52,460,901 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	41,121,421 - 41,202,780 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	41,124,373 - 41,205,732 (+)	NCBI
Celera	6	39,444,624 - 39,525,709 (+)	NCBI		Celera
Cytogenetic Map	6	q16	NCBI

NOL10
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	10,570,754 - 10,689,975 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	10,562,347 - 10,689,987 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	10,710,880 - 10,830,101 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	10,628,345 - 10,747,549 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	2	10,625,984 - 10,745,255 (-)	NCBI		Celera
Cytogenetic Map	2	p25.1	NCBI
HuRef	2	10,563,758 - 10,682,602 (-)	NCBI		HuRef
CHM1_1	2	10,639,886 - 10,759,678 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	10,600,793 - 10,720,003 (-)	NCBI		T2T-CHM13v2.0

Nol10
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	17,398,423 - 17,480,101 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	17,398,459 - 17,480,096 (+)	Ensembl		GRCm39 Ensembl
GRCm38	12	17,348,421 - 17,430,095 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	17,348,458 - 17,430,095 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	17,355,299 - 17,436,901 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	17,373,973 - 17,455,575 (+)	NCBI		MGSCv36	mm8
Celera	12	17,669,996 - 17,752,099 (+)	NCBI		Celera
Cytogenetic Map	12	A1.1	NCBI
cM Map	12	8.07	NCBI

Nol10
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955487	5,655,212 - 5,700,901 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955487	5,655,378 - 5,701,017 (-)	NCBI	ChiLan1.0	ChiLan1.0

NOL10
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	115,826,925 - 115,943,615 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	115,830,963 - 115,947,586 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	10,572,008 - 10,688,682 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	10,725,617 - 10,842,189 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	10,725,617 - 10,842,190 (-)	Ensembl	panpan1.1		panPan2

NOL10
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	7,490,387 - 7,574,342 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	7,490,916 - 7,574,331 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	7,415,812 - 7,499,502 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	7,588,111 - 7,675,719 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	7,588,116 - 7,675,720 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	7,478,378 - 7,562,274 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	7,481,059 - 7,564,723 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	7,495,158 - 7,578,634 (-)	NCBI		UU_Cfam_GSD_1.0

Nol10
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	51,948,295 - 52,031,772 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936532	6,706,592 - 6,786,703 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936532	6,705,878 - 6,786,810 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NOL10
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	125,861,432 - 125,956,887 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	125,861,422 - 125,956,626 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	134,629,274 - 134,723,599 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NOL10
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	96,929,399 - 97,045,962 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	14	96,929,085 - 97,047,597 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666045	15,250,130 - 15,365,623 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nol10
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624865	4,747,787 - 4,798,734 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624865	4,747,674 - 4,800,822 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nol10
374 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	80
Count of miRNA genes:	73
Interacting mature miRNAs:	75
Transcripts:	ENSRNOT00000007169
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	41223769	Rat
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1	41223769	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1	41223769	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1	41223769	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1	41223769	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	1	42487980	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	1	42487980	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	1	42487980	Rat
7411584	Foco4	Food consumption QTL 4	4.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	42838846	Rat
738024	Sach5	Saccharine consumption QTL 5	3.9	0.00039	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	6	1	43394190	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	72227641	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	54641141	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
1578665	Bss16	Bone structure and strength QTL 16	4.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	6	11735669	72593685	Rat
1578668	Bmd14	Bone mineral density QTL 14	3.8		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	11735669	72593685	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	14368788	59368788	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	14368788	59368788	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	15107216	107351382	Rat
2292589	Emca10	Estrogen-induced mammary cancer QTL 10		0.048	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	16536140	61536140	Rat
1354664	Slep2	Serum leptin concentration QTL 2	4.49		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	6	16536140	71636405	Rat
1641898	Colcr4	Colorectal carcinoma resistance QTL4	3.71	0.0007	intestine integrity trait (VT:0010554)	well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)	6	20338777	62613667	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
1331779	Rf38	Renal function QTL 38	2.876		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	32074428	72227641	Rat
634318	Bw118	Body weight QTL 118	3.55		abdominal fat pad mass (VT:1000711)	abdominal fat pad weight (CMO:0000088)	6	33309549	57730294	Rat
6893340	Cm77	Cardiac mass QTL 77	0.26	0.57	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	33309549	81132889	Rat
1300143	Rf14	Renal function QTL 14	2.92		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	34434137	77102317	Rat
1354632	Scl29	Serum cholesterol level QTL 29	3.74		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	6	35098709	71636405	Rat
634307	Bp141	Blood pressure QTL 141	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	35230417	80230417	Rat
70199	Coreg1	Compensatory renal growth QTL 1	11.8		kidney mass (VT:0002707)	compensatory renal growth score (CMO:0001894)	6	35691618	57730540	Rat
9590290	Uminl2	Urine mineral level QTL 2	3.96	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	6	38783989	83783989	Rat
9590306	Scort18	Serum corticosterone level QTL 18	2.88	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat
9590140	Scort4	Serum corticosterone level QTL 4	14.49	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat

Markers in Region

AI579107

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	40,225,152 - 40,225,257 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	42,744,899 - 42,745,003	NCBI	Rnor6.0
Rnor_5.0	6	52,460,701 - 52,460,805	UniSTS	Rnor5.0
RGSC_v3.4	6	41,202,580 - 41,202,684	UniSTS	RGSC3.4
Celera	6	39,525,509 - 39,525,613	UniSTS
RH 3.4 Map	6	197.4	UniSTS
Cytogenetic Map	6	q16	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	26	32	16	19	16			74	21	34	11
Low		17	25	25		25	8	11		14	7		8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261889	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063261890	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005505511	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC081954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000007169 ⟹ ENSRNOP00000007169

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	40,144,235 - 40,225,353 (+)	Ensembl
Rnor_6.0 Ensembl	6	42,656,616 - 42,745,098 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000118181 ⟹ ENSRNOP00000076483

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	40,144,235 - 40,222,055 (+)	Ensembl

RefSeq Acc Id:

NM_001014076 ⟹ NP_001014098

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	45,872,981 - 45,954,067 (+)	NCBI
mRatBN7.2	6	40,144,266 - 40,225,353 (+)	NCBI
Rnor_6.0	6	42,656,661 - 42,745,099 (+)	NCBI
Rnor_5.0	6	52,376,044 - 52,460,901 (+)	NCBI
RGSC_v3.4	6	41,121,421 - 41,202,780 (+)	RGD
Celera	6	39,444,624 - 39,525,709 (+)	RGD

Sequence:

show sequence

TTTGGATTCAGGCGTATTCTGCTGGGCCGGCGTTCTGTGACTGCGTGCCGGACTCCGGCTTCTC
TGCGCCGCGATGCAGGTCTCCAGCCTCAACGAAGTGAAGATTTACAGCCTCAGCTGCGGCAAGT
CTCTCCCTGAGTGGCTTTCCGACAGGAAGAAGAGGGCACTGCAGAAGAAGGATGTCGATGTTCG
TAGGAGAATTGAACTTATCCAGGACTTTGAAATGCCTACTGTGTGTACTACTATCAAGGTGTCG
AAAGATGGACAGTATATTTTAGCAACTGGAACATATAAGCCTCGAGTCCGGTGTTATGACACCT
ATCAGTTATCCCTGAAATTTGAAAGGTGCTTGGATTCTGAAGTTGTCACCTTTGAGATTTTATC
AGACGACTATTCAAAGATTGTCTTCTTACATAACGACAGATATATTGAATTTCACTCACAATCA
GGATTTTACTACAAAACCAGAATTCCCAAGTTCGGCCGAGACTTCTCTTACCACTATCCATCCT
GTGACTTGTACTTCGTAGGTGCAAGCTCTGAAGTTTATAGATTAAACTTAGAACAAGGGCGGTA
CCTGAATCCTCTCCAGACGGATGCTGCGGAGAACAATGTTTGTGACATAAACACAGTGCATGGC
TTGTTCGCCACAGGAACAATAGAGGGTCGAGTGGAATGCTGGGATCCAAGAGTAAGAAAAAGGG
TTGGTGTGTTAGACTGTGCATTAAACAGTGTCACAGCAGATTCAGAGATAAACAGCTTACCCAC
CATCTCTGCGTTGAAGTTTAATGGAGCCTTGAGCATGGCAGTTGGAACATCCACAGGGCAGGTA
TTGTTATATGATCTTCGCTCAGATAAGCCATTGCTAGTTAAGGATCACCAGTATGGACTGCCCA
TTAAGTCAGTTCATTTCCAGGACTCACTAGATTTGGTTTTGTCTGCAGACTCCAGAATTGTCAA
AATGTGGAACAAGGACTCCGGGAAGATATTTACTTCGTTGGAGCCGGAACATGACCTTAATGAT
GTTTGCCTCTATCCCAGCTCAGGAATGATTCTTACTGCCAATGAATCCCCCAAGATGGGCATTT
ACTACATTCCGGTTTTGGGTCCTGCCCCCAGGTGGTGTTCCTTCCTGGACAACTTGACAGAAGA
ATTAGAAGAGAATCCAGAGAGCACAGTGTATGATGATTACAAATTTGTCACCAAGAAAGACCTT
GAAAATTTAGGGCTCACACATCTCATTGGATCACCTTTCCTCCGAGCATATATGCATGGGTTTT
TCATGGATATCAGACTCTACCACAAGGTGAAATTGATGGTCAATCCATTTGCTTATGAAGAATA
TAGGAAAGATAAAATTCGACAGAAAATAGAAGAAACACGTGCACAGAGAGTCCAGTTAAAGAAA
CTTCCAAAAGTTAACAAAGAACTGGCACTTAAATTAATTGAAGAGGAAGAGGAGAAGCAGAAAT
CGACACTGAAAAAGAAAGTTAAGAGCCTCCCTAATATCCTCACGGACGATCGATTTAAAGTTAT
GTTTGAGAACCCCGACTTCCAGGTGGATGAAGACAGTGAAGAGTTCAGGCTTCTCAATCCACTT
GTCTCGAGGATTAGTGAGAAGAGGAAGAAGCAGCTGAGACTCTTGGAGCAGCAGGAGCAGCTCA
AGAATGAAGAGGAGGAAGAACCGGAAGGAAAACCCAGTGATGCAGAAAGTTCAGAGAGTTCAGA
TGATGAAAAAGATTGGGTTGAAGAAGTCAGGAAGCAACGCAGACTCCTGCAGCAGGAAGAAAGA
GTGAAGCGGCAGGAGCAACTGAAGGAGGACCAACAGACAGTCCTGAAGCCCCAGTTCTACGAGA
TCAAAGCAGGCGAAGAGTTCAGGAGCTTCAAAGAGTCCGCCACCAAGCAGAAACTGATGAACAA
AACTCTGGAAGATCGCTTGAAACTTGAAGCAAAACATGGGACCTTGAGTGTGTCAGACACCACT
GTTGGCAGCAAGCAGTTGACATTTACTCTCAAGAGGTCTGAACAGCAAAAGAAGCAACAAGAGG
CTGAGAAACTGCATCGTCAGGAAAGGAAAAAGCTGCGTAGGTCTGCCAGCCACCTGAGGTCCAG
ACCCAGAAGAGGCCGGCCCTTTCACTGACCAAAGGAGTGAGCCTACAAACAACTTGGAAACTGT
TTCTCCCCATGGATTCTCACAAGGGCATCACACCCAGACGAGGGAGTGTGGTAGTTAAAACTAC
ACGTAGATGTGTGTGTGTGCATGGTGCTGGTGGTCTGACCGGCCCACTACCCGGCTCCAGTAGT
CCCTGGCTCCGGGAGCTTTTTCCAAGTCACTGCCCTTTTGAATATTGTCTTCTCTCCTGCTGAT
GATCAGAGAAAGCAGTCATCATTTCTAATATTGGAAAGGTCTACATAAAATGAAAAGTTTTATT
TCTGCTGGAAACAACGGATTATCATGTTATAAGAATGGTTTGGTTTTTTGGTTTGGTTGGTTGG
TTGGTTGGTTTGAGACAGGGTTTCTCTATGTAGCCTTGAGTGTCCTGGAACTCATAAAGATCCA
CGTGCCTCTGCCTCCTAAGTGCTGAAGTTAAAGGGAGGCACCACCATGCCAGCCAGAAAGTCTG
TCCTCACTGTCTTCTGCCCCTCAGGACTGAGTGAAGTCCTGCCCTTATTTGCCCGGTATCTGCT
GATTGGCCCTGTCTGTGTGCATGAGTATGTTTGCAGGCTTACTTGCTTGCTTTTGTATTCCTTT
GGTATACTGTTTAAACTATTTTTATATCAAGAGTGTAAATCAATGGTAATAAATAATAAGTGAA
CTCTAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_063261889 ⟹ XP_063117959

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	45,861,773 - 45,954,067 (+)	NCBI

RefSeq Acc Id:

XM_063261890 ⟹ XP_063117960

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	45,894,068 - 45,954,067 (+)	NCBI

RefSeq Acc Id:

XR_005505511

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	45,872,941 - 45,929,444 (+)	NCBI
mRatBN7.2	6	40,144,217 - 40,200,759 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014098	(Get FASTA)	NCBI Sequence Viewer
	XP_063117959	(Get FASTA)	NCBI Sequence Viewer
	XP_063117960	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH81954	(Get FASTA)	NCBI Sequence Viewer
	EDM03152	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007169
	ENSRNOP00000007169.5
	ENSRNOP00000076483.1
	ENSRNOP00055006883
	ENSRNOP00060004931
	ENSRNOP00065005883
GenBank Protein	Q66H99	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001014098 ⟸ NM_001014076

- UniProtKB:

Q66H99 (UniProtKB/Swiss-Prot), A6HAU7 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MQVSSLNEVKIYSLSCGKSLPEWLSDRKKRALQKKDVDVRRRIELIQDFEMPTVCTTIKVSKDG
QYILATGTYKPRVRCYDTYQLSLKFERCLDSEVVTFEILSDDYSKIVFLHNDRYIEFHSQSGFY
YKTRIPKFGRDFSYHYPSCDLYFVGASSEVYRLNLEQGRYLNPLQTDAAENNVCDINTVHGLFA
TGTIEGRVECWDPRVRKRVGVLDCALNSVTADSEINSLPTISALKFNGALSMAVGTSTGQVLLY
DLRSDKPLLVKDHQYGLPIKSVHFQDSLDLVLSADSRIVKMWNKDSGKIFTSLEPEHDLNDVCL
YPSSGMILTANESPKMGIYYIPVLGPAPRWCSFLDNLTEELEENPESTVYDDYKFVTKKDLENL
GLTHLIGSPFLRAYMHGFFMDIRLYHKVKLMVNPFAYEEYRKDKIRQKIEETRAQRVQLKKLPK
VNKELALKLIEEEEEKQKSTLKKKVKSLPNILTDDRFKVMFENPDFQVDEDSEEFRLLNPLVSR
ISEKRKKQLRLLEQQEQLKNEEEEEPEGKPSDAESSESSDDEKDWVEEVRKQRRLLQQEERVKR
QEQLKEDQQTVLKPQFYEIKAGEEFRSFKESATKQKLMNKTLEDRLKLEAKHGTLSVSDTTVGS
KQLTFTLKRSEQQKKQQEAEKLHRQERKKLRRSASHLRSRPRRGRPFH

hide sequence

RefSeq Acc Id:

ENSRNOP00000007169 ⟸ ENSRNOT00000007169

RefSeq Acc Id:

ENSRNOP00000076483 ⟸ ENSRNOT00000118181

RefSeq Acc Id:	XP_063117959 ⟸ XM_063261889
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_063117960 ⟸ XM_063261890
- Peptide Label:	isoform X2

Protein Domains

NUC153

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q66H99-F1-model_v2	AlphaFold	Q66H99	1-688	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694509

Promoter ID:

EPDNEW_R5033

Type:

initiation region

Name:

Nol10_1

Description:

nucleolar protein 10

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	42,656,629 - 42,656,689	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1359447	AgrOrtholog
BioCyc Gene	G2FUF-38056	BioCyc
Ensembl Genes	ENSRNOG00000005344	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055005620	UniProtKB/Swiss-Prot
	ENSRNOG00060003937	UniProtKB/Swiss-Prot
	ENSRNOG00065005615	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000007169	ENTREZGENE
	ENSRNOT00000007169.7	UniProtKB/Swiss-Prot
	ENSRNOT00000118181.1	UniProtKB/TrEMBL
	ENSRNOT00055009039	UniProtKB/Swiss-Prot
	ENSRNOT00060006582	UniProtKB/Swiss-Prot
	ENSRNOT00065008360	UniProtKB/Swiss-Prot
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7122941	IMAGE-MGC_LOAD
InterPro	NOL10/Enp2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NUC153	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:313981	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:94045	IMAGE-MGC_LOAD
NCBI Gene	313981	ENTREZGENE
PANTHER	NUCLEOLAR PROTEIN 10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR14927	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	NUC153	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Nol10	PhenoGen
RatGTEx	ENSRNOG00000005344	RatGTEx
	ENSRNOG00055005620	RatGTEx
	ENSRNOG00060003937	RatGTEx
	ENSRNOG00065005615	RatGTEx
SMART	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZK33_RAT	UniProtKB/TrEMBL
	A6HAU7	ENTREZGENE, UniProtKB/TrEMBL
	NOL10_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2006-03-30	Nol10	nucleolar protein 10	LOC313981	similar to hypothetical protein FLJ14075	Symbol and Name updated	1299863	APPROVED
2005-07-29	LOC313981	similar to hypothetical protein FLJ14075			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar