Or7c19 (olfactory receptor family 7 subfamily C member 19) - Rat Genome Database

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Gene: Or7c19 (olfactory receptor family 7 subfamily C member 19) Rattus norvegicus
Analyze
No known orthologs.
Symbol: Or7c19
Name: olfactory receptor family 7 subfamily C member 19
RGD ID: 1333226
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in signal transduction. Predicted to be active in plasma membrane; INTERACTS WITH bisphenol A.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 1666; olfactory receptor gene Olr1666; olfactory receptor Olr1666; Olr1666; ratchr19-23198893-23197955_ORF
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81938,005,257 - 38,105,125 (-)NCBIGRCr8
mRatBN7.21921,832,413 - 21,834,841 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1921,832,051 - 21,838,365 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1923,522,624 - 23,523,562 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01928,717,148 - 28,718,086 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01931,679,952 - 31,680,890 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01927,534,833 - 27,546,304 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1927,534,854 - 27,535,792 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01938,498,265 - 38,503,364 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41923,193,129 - 23,194,067 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11923,197,954 - 23,198,893 (-)NCBI
Celera1921,692,043 - 21,692,981 (-)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
bisphenol A  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Variants

.
Variants in Or7c19
12 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:52
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000024040
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411590Foco7Food consumption QTL 76.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)19124688055Rat
10054132Srcrt9Stress Responsive Cort QTL 92.870.0017blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19127355345Rat
631678Cm9Cardiac mass QTL 94.270.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)19128982497Rat
631681Cm12Cardiac mass QTL 123.330.00053heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)19128982497Rat
1549847Bss8Bone structure and strength QTL 84lumbar vertebra strength trait (VT:0010574)vertebra ultimate force (CMO:0001678)19131963836Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
631840Niddm38Non-insulin dependent diabetes mellitus QTL 383.86blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)191032318023069265Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
61407Scl12Serum cholesterol level QTL 120.001blood HDL cholesterol amount (VT:0000184)serum high density lipoprotein cholesterol level (CMO:0000361)191392640130303727Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium
Low 8 4
Below cutoff 1 7 15 4 13 4 6 7 18 9 16 5 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000024040   ⟹   ENSRNOP00000024040
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1921,832,051 - 21,838,365 (-)Ensembl
Rnor_6.0 Ensembl1927,534,854 - 27,535,792 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107361   ⟹   ENSRNOP00000096693
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1921,832,051 - 21,838,365 (-)Ensembl
RefSeq Acc Id: NM_001000108   ⟹   NP_001000108
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81938,005,899 - 38,006,837 (-)NCBI
mRatBN7.21921,832,632 - 21,833,570 (-)NCBI
Rnor_6.01927,534,854 - 27,535,792 (-)NCBI
Rnor_5.01938,498,265 - 38,503,364 (-)NCBI
RGSC_v3.41923,193,129 - 23,194,067 (-)RGD
Celera1921,692,043 - 21,692,981 (-)RGD
Sequence:
RefSeq Acc Id: XM_006255359   ⟹   XP_006255421
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81938,005,257 - 38,017,522 (-)NCBI
mRatBN7.21921,832,413 - 21,834,841 (-)NCBI
Rnor_6.01927,534,833 - 27,537,441 (-)NCBI
Rnor_5.01938,498,265 - 38,503,364 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063277875   ⟹   XP_063133945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81938,005,257 - 38,105,125 (-)NCBI
RefSeq Acc Id: XM_063277876   ⟹   XP_063133946
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81938,005,257 - 38,086,232 (-)NCBI
RefSeq Acc Id: XM_063277877   ⟹   XP_063133947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81938,005,257 - 38,011,721 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001000108   ⟸   NM_001000108
- UniProtKB: D3ZDG9 (UniProtKB/TrEMBL),   A6KDF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255421   ⟸   XM_006255359
- Peptide Label: isoform X1
- UniProtKB: D3ZDG9 (UniProtKB/TrEMBL),   A6KDF2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000024040   ⟸   ENSRNOT00000024040
RefSeq Acc Id: ENSRNOP00000096693   ⟸   ENSRNOT00000107361
RefSeq Acc Id: XP_063133945   ⟸   XM_063277875
- Peptide Label: isoform X1
- UniProtKB: A6KDF2 (UniProtKB/TrEMBL),   D3ZDG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133946   ⟸   XM_063277876
- Peptide Label: isoform X1
- UniProtKB: A6KDF2 (UniProtKB/TrEMBL),   D3ZDG9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063133947   ⟸   XM_063277877
- Peptide Label: isoform X1
- UniProtKB: A6KDF2 (UniProtKB/TrEMBL),   D3ZDG9 (UniProtKB/TrEMBL)
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZDG9-F1-model_v2 AlphaFold D3ZDG9 1-312 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333226 AgrOrtholog
BioCyc Gene G2FUF-6197 BioCyc
Ensembl Genes ENSRNOG00000017868 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024040.3 UniProtKB/TrEMBL
  ENSRNOT00000107361.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:291929 UniProtKB/TrEMBL
NCBI Gene 291929 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR 7C1 UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or7c19 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017868 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6KDF2 ENTREZGENE, UniProtKB/TrEMBL
  D3ZDG9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or7c19  olfactory receptor family 7 subfamily C member 19  Olr1666  olfactory receptor 1666  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr1666  olfactory receptor 1666   Olr1666_predicted  olfactory receptor 1666 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr1666_predicted  olfactory receptor 1666 (predicted)      Symbol and Name status set to approved 70820 APPROVED