Crlf1 (cytokine receptor-like factor 1) - Rat Genome Database

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Gene: Crlf1 (cytokine receptor-like factor 1) Rattus norvegicus
Analyze
Symbol: Crlf1
Name: cytokine receptor-like factor 1
RGD ID: 1311371
Description: Predicted to enable cytokine binding activity and cytokine receptor activity. Predicted to contribute to ciliary neurotrophic factor receptor binding activity and cytokine activity. Predicted to be involved in several processes, including negative regulation of motor neuron apoptotic process; positive regulation of tyrosine phosphorylation of STAT protein; and ureteric bud development. Predicted to be part of CRLF-CLCF1 complex and receptor complex. Predicted to be active in external side of plasma membrane. Human ortholog(s) of this gene implicated in cold-induced sweating syndrome 1. Orthologous to human CRLF1 (cytokine receptor like factor 1); INTERACTS WITH 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC290655
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,958,695 - 18,970,026 (-)NCBIGRCr8
mRatBN7.21618,924,722 - 18,936,049 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,924,722 - 18,935,997 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,966,510 - 18,977,787 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,099,327 - 20,110,590 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,019,472 - 19,030,749 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,675,042 - 20,686,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,675,042 - 20,686,317 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,530,521 - 20,541,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,431,472 - 19,442,747 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,431,472 - 19,442,745 (-)NCBI
Celera1619,116,098 - 19,127,373 (-)NCBICelera
Cytogenetic Map16p14NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP,ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dinitrobenzenesulfonic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP,ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrylamide  (EXP,ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP)
amitrole  (EXP)
antirheumatic drug  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butanal  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
cisplatin  (ISO)
Cuprizon  (EXP)
cypermethrin  (EXP)
D-glucose  (ISO)
diazinon  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
folic acid  (ISO)
fucoxanthin  (ISO)
furan  (EXP)
glucose  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
maneb  (ISO)
methimazole  (EXP)
methylmercury chloride  (EXP)
miconazole  (ISO)
niclosamide  (ISO)
ochratoxin A  (ISO)
ozone  (ISO)
paracetamol  (EXP)
paraquat  (EXP,ISO)
PCB138  (ISO)
pentanal  (ISO)
perfluorooctanoic acid  (ISO)
progesterone  (ISO)
propanal  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
SB 431542  (ISO)
sodium arsenite  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (ISO)
tributylstannane  (EXP)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Cold-induced sweating syndrome is caused by mutations in the CRLF1 gene. Knappskog PM, etal., Am J Hum Genet. 2003 Feb;72(2):375-83. Epub 2002 Dec 31.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:10966616   PMID:14523086   PMID:15034937   PMID:16545622   PMID:24006456  


Genomics

Comparative Map Data
Crlf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81618,958,695 - 18,970,026 (-)NCBIGRCr8
mRatBN7.21618,924,722 - 18,936,049 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1618,924,722 - 18,935,997 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1618,966,510 - 18,977,787 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01620,099,327 - 20,110,590 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01619,019,472 - 19,030,749 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01620,675,042 - 20,686,365 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1620,675,042 - 20,686,317 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,530,521 - 20,541,831 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,431,472 - 19,442,747 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11619,431,472 - 19,442,745 (-)NCBI
Celera1619,116,098 - 19,127,373 (-)NCBICelera
Cytogenetic Map16p14NCBI
CRLF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381918,593,237 - 18,606,799 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1918,572,220 - 18,607,741 (-)EnsemblGRCh38hg38GRCh38
GRCh371918,704,047 - 18,717,609 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361918,565,047 - 18,578,660 (-)NCBINCBI36Build 36hg18NCBI36
Build 341918,565,046 - 18,578,660NCBI
Celera1918,606,237 - 18,619,858 (-)NCBICelera
Cytogenetic Map19p13.11NCBI
HuRef1918,266,624 - 18,309,213 (-)NCBIHuRef
CHM1_11918,704,266 - 18,717,662 (-)NCBICHM1_1
T2T-CHM13v2.01918,728,303 - 18,741,874 (-)NCBIT2T-CHM13v2.0
Crlf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,945,798 - 70,956,728 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl870,945,808 - 70,956,731 (+)EnsemblGRCm39 Ensembl
GRCm38870,493,097 - 70,504,078 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,493,158 - 70,504,081 (+)EnsemblGRCm38mm10GRCm38
MGSCv37873,017,055 - 73,027,980 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36873,422,145 - 73,433,070 (+)NCBIMGSCv36mm8
Celera873,049,567 - 73,060,492 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
cM Map834.15NCBI
Crlf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,998,260 - 3,003,283 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,998,258 - 3,003,553 (+)NCBIChiLan1.0ChiLan1.0
CRLF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22023,452,262 - 23,465,525 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11922,460,674 - 22,473,911 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01918,070,465 - 18,083,701 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11919,040,355 - 19,048,927 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,040,682 - 19,046,584 (-)Ensemblpanpan1.1panPan2
CRLF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12044,466,812 - 44,476,055 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2044,466,810 - 44,472,637 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2044,376,895 - 44,389,992 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02044,948,405 - 44,961,499 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2044,948,246 - 44,958,835 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12044,185,771 - 44,198,860 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02044,595,729 - 44,608,819 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02044,871,168 - 44,884,262 (+)NCBIUU_Cfam_GSD_1.0
Crlf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118203,147,220 - 203,153,304 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365962,693,881 - 2,702,131 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365962,693,881 - 2,702,443 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CRLF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl259,222,367 - 59,233,720 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1259,222,551 - 59,233,723 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2259,069,084 - 59,075,048 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CRLF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,061,289 - 17,074,930 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl617,061,621 - 17,074,794 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660742,261,781 - 2,275,479 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Crlf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249081,752,779 - 1,762,244 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249081,752,773 - 1,762,272 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Crlf1
39 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:35
Interacting mature miRNAs:38
Transcripts:ENSRNOT00000060097
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1600369Hcas8Hepatocarcinoma susceptibility QTL 8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)16122477621Rat
631830Alc7Alcohol consumption QTL 72.9consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16126727669Rat
634355Rends4Renal damage susceptibility QTL 40.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)16126727669Rat
1582235Insul8Insulin level QTL 83.30.0063blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)16126727669Rat
9590151Scort8Serum corticosterone level QTL 88.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)16130836262Rat
2302380Slep6Serum leptin concentration QTL 63.36blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)16132139025Rat
2307172Activ4Activity QTL 43.710.00023locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)16133418960Rat
1354584Despr6Despair related QTL 63.10.0067locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16139533930Rat
2303566Bw90Body weight QTL 902body mass (VT:0001259)body weight (CMO:0000012)16139533930Rat
631561Hcuc2Hepatic copper content QTL 22.8liver copper amount (VT:0003065)liver total copper weight (CMO:0001507)16139533949Rat
6903319Bw114Body weight QTL 1142.70.0037body mass (VT:0001259)body weight (CMO:0000012)16143534949Rat
7411664Foco30Food consumption QTL 30110.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)16144588133Rat
1354625Despr7Despair related QTL 73.160.016locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)16144977551Rat
1600378Arunc4Aerobic running capacity QTL 40.03exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)1638024580345693Rat
2293343Glom16Glomerulus QTL 167.4kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1683223646053497Rat
2312660Bw95Body weight QTL 950.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)1683223659492508Rat
2312663Slep9Serum leptin concentration QTL 90.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)1683223659492508Rat
2312666Insul16Insulin level QTL 160.01blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1683223659492508Rat
2312669Stl23Serum triglyceride level QTL 230.01blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)1683223659492508Rat
1300133Rf24Renal function QTL 243.64blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)16338015021361552Rat
2306902Bp339Blood pressure QTL 3390.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16338015043025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760943025077Rat
70183BpQTLcluster13Blood pressure QTL cluster 133.654arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)16422760943025077Rat
737819Hcas4Hepatocarcinoma susceptibility QTL 44.43liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)16422760946975965Rat
61405Niddm6Non-insulin dependent diabetes mellitus QTL 63.660.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)16422760948972724Rat
61338Bp23Blood pressure QTL 234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)16422760949227609Rat
737826Alc11Alcohol consumption QTL 113.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)16422760960252231Rat
631517Scl9Serum cholesterol level QTL 93.3blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)161572643321034895Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor depth of invasion (CMO:0001888)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat
70205Gcr3Gastric cancer resistance QTL 32.3stomach morphology trait (VT:0000470)stomach tumor diameter (CMO:0001889)161769679182635055Rat

Markers in Region
RH128982  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21618,924,775 - 18,924,931 (+)MAPPERmRatBN7.2
Rnor_6.01620,675,096 - 20,675,251NCBIRnor6.0
Rnor_5.01620,530,575 - 20,530,730UniSTSRnor5.0
RGSC_v3.41619,431,526 - 19,431,681UniSTSRGSC3.4
Celera1619,116,152 - 19,116,307UniSTS
RH 3.4 Map16214.42UniSTS
Cytogenetic Map16p14UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 1 2 22 4 13 11
Low 3 21 12 4 3 4 8 9 42 19 27 8
Below cutoff 19 19 11 16 11 10 12 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000060097   ⟹   ENSRNOP00000056846
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1618,924,722 - 18,935,997 (-)Ensembl
Rnor_6.0 Ensembl1620,675,042 - 20,686,317 (-)Ensembl
RefSeq Acc Id: NM_001106074   ⟹   NP_001099544
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,695 - 18,969,970 (-)NCBI
mRatBN7.21618,924,722 - 18,935,997 (-)NCBI
Rnor_6.01620,675,042 - 20,686,317 (-)NCBI
Rnor_5.01620,530,521 - 20,541,831 (-)NCBI
RGSC_v3.41619,431,472 - 19,442,747 (-)RGD
Celera1619,116,098 - 19,127,373 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252872   ⟹   XP_006252934
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,024 (-)NCBI
mRatBN7.21618,924,733 - 18,936,047 (-)NCBI
Rnor_6.01620,675,052 - 20,686,365 (-)NCBI
Rnor_5.01620,530,521 - 20,541,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006252874   ⟹   XP_006252936
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,024 (-)NCBI
mRatBN7.21618,924,733 - 18,936,048 (-)NCBI
Rnor_6.01620,675,052 - 20,686,365 (-)NCBI
Rnor_5.01620,530,521 - 20,541,831 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039094330   ⟹   XP_038950258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,026 (-)NCBI
mRatBN7.21618,924,733 - 18,936,049 (-)NCBI
RefSeq Acc Id: XM_039094331   ⟹   XP_038950259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,958,706 - 18,970,025 (-)NCBI
mRatBN7.21618,924,733 - 18,936,048 (-)NCBI
RefSeq Acc Id: XM_039094332   ⟹   XP_038950260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81618,960,134 - 18,970,026 (-)NCBI
mRatBN7.21618,926,161 - 18,936,049 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001099544   ⟸   NM_001106074
- Peptide Label: precursor
- UniProtKB: A6KA48 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252934   ⟸   XM_006252872
- Peptide Label: isoform X3
- UniProtKB: D3ZIV9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252936   ⟸   XM_006252874
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSRNOP00000056846   ⟸   ENSRNOT00000060097
RefSeq Acc Id: XP_038950258   ⟸   XM_039094330
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038950259   ⟸   XM_039094331
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038950260   ⟸   XM_039094332
- Peptide Label: isoform X5
Protein Domains
Fibronectin type-III

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZIV9-F1-model_v2 AlphaFold D3ZIV9 1-425 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13700031
Promoter ID:EPDNEW_R10553
Type:multiple initiation site
Name:Crlf1_1
Description:cytokine receptor-like factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01620,686,325 - 20,686,385EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311371 AgrOrtholog
BioCyc Gene G2FUF-11782 BioCyc
Ensembl Genes ENSRNOG00000020030 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000060097.3 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
InterPro Fibronectin_type3 UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Growth/epo_recpt_lig-bind UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
KEGG Report rno:290655 UniProtKB/TrEMBL
NCBI Gene 290655 ENTREZGENE
PANTHER CYTOKINE RECEPTOR UniProtKB/TrEMBL
  CYTOKINE RECEPTOR-LIKE FACTOR 1 UniProtKB/TrEMBL
Pfam EpoR_lig-bind UniProtKB/TrEMBL
  fn3 UniProtKB/TrEMBL
PhenoGen Crlf1 PhenoGen
PROSITE FN3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000020030 RatGTEx
SMART FN3 UniProtKB/TrEMBL
Superfamily-SCOP FN_III-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt A6KA48 ENTREZGENE, UniProtKB/TrEMBL
  D3ZIV9 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Crlf1  cytokine receptor-like factor 1   Crlf1_predicted  cytokine receptor-like factor 1 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Crlf1_predicted  cytokine receptor-like factor 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED