Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | squamous cell carcinoma | | ISO | AFAP1L2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:29059373 | |
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Imported Disease Annotations - CTDTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | squamous cell carcinoma | | ISO | AFAP1L2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | PMID:29059373 | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
3. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Afap1l2 (Rattus norvegicus - Norway rat) |
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AFAP1L2 (Homo sapiens - human) |
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Afap1l2 (Mus musculus - house mouse) |
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Afap1l2 (Chinchilla lanigera - long-tailed chinchilla) |
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AFAP1L2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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AFAP1L2 (Canis lupus familiaris - dog) |
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Afap1l2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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AFAP1L2 (Sus scrofa - pig) |
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AFAP1L2 (Chlorocebus sabaeus - green monkey) |
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Afap1l2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Afap1l2
750 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH143842 |
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alimentary part of gastrointestinal system | circulatory system | endocrine system | exocrine system | hemolymphoid system | hepatobiliary system | integumental system | musculoskeletal system | nervous system | renal system | reproductive system | respiratory system | appendage | |
High | |||||||||||||
Medium | 4 | 11 | 1 | 1 | 26 | 18 | 26 | 11 | 1 | ||||
Low | 3 | 39 | 57 | 41 | 8 | 41 | 7 | 10 | 48 | 17 | 15 | 7 | |
Below cutoff |
RefSeq Transcripts | NM_001305184 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_008760580 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_008760581 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017588861 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017588862 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_017588863 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282799 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282800 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282801 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282802 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282803 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282804 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_063282805 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AB568258 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
CH473986 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000001 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
RefSeq Acc Id: | ENSRNOT00000023113 ⟹ ENSRNOP00000023113 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000073346 ⟹ ENSRNOP00000064164 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000084915 ⟹ ENSRNOP00000073158 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000105824 ⟹ ENSRNOP00000081810 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000109408 ⟹ ENSRNOP00000081451 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | ENSRNOT00000110011 ⟹ ENSRNOP00000097019 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001305184 ⟹ NP_001292113 | ||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_008760580 ⟹ XP_008758802 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_017588861 ⟹ XP_017444350 | ||||||||||||||||
Type: | CODING | ||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063282799 ⟹ XP_063138869 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282800 ⟹ XP_063138870 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282801 ⟹ XP_063138871 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282802 ⟹ XP_063138872 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282803 ⟹ XP_063138873 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282804 ⟹ XP_063138874 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063282805 ⟹ XP_063138875 | ||||||||
Type: | CODING | ||||||||
Position: |
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Protein RefSeqs | NP_001292113 | (Get FASTA) | NCBI Sequence Viewer |
XP_008758802 | (Get FASTA) | NCBI Sequence Viewer | |
XP_017444350 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138869 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138870 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138871 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138872 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138873 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138874 | (Get FASTA) | NCBI Sequence Viewer | |
XP_063138875 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | BAK39958 | (Get FASTA) | NCBI Sequence Viewer |
EDL94507 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000023113.6 | ||
ENSRNOP00000064164 | |||
ENSRNOP00000064164.3 | |||
ENSRNOP00000081451.1 | |||
ENSRNOP00000081810.1 | |||
ENSRNOP00000097019 | |||
ENSRNOP00000097019.1 |
RefSeq Acc Id: | XP_008758802 ⟸ XM_008760580 |
- Peptide Label: | isoform X1 |
- UniProtKB: | F1M5W8 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | NP_001292113 ⟸ NM_001305184 |
- UniProtKB: | M0R484 (UniProtKB/TrEMBL), F1M5W8 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_017444350 ⟸ XM_017588861 |
- Peptide Label: | isoform X3 |
- UniProtKB: | A0A8I6ARV2 (UniProtKB/TrEMBL), F1M5W8 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | ENSRNOP00000073158 ⟸ ENSRNOT00000084915 |
RefSeq Acc Id: | ENSRNOP00000064164 ⟸ ENSRNOT00000073346 |
RefSeq Acc Id: | ENSRNOP00000023113 ⟸ ENSRNOT00000023113 |
RefSeq Acc Id: | ENSRNOP00000081810 ⟸ ENSRNOT00000105824 |
RefSeq Acc Id: | ENSRNOP00000097019 ⟸ ENSRNOT00000110011 |
RefSeq Acc Id: | ENSRNOP00000081451 ⟸ ENSRNOT00000109408 |
RefSeq Acc Id: | XP_063138869 ⟸ XM_063282799 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_063138874 ⟸ XM_063282804 |
- Peptide Label: | isoform X8 |
RefSeq Acc Id: | XP_063138870 ⟸ XM_063282800 |
- Peptide Label: | isoform X4 |
RefSeq Acc Id: | XP_063138873 ⟸ XM_063282803 |
- Peptide Label: | isoform X7 |
RefSeq Acc Id: | XP_063138872 ⟸ XM_063282802 |
- Peptide Label: | isoform X6 |
RefSeq Acc Id: | XP_063138871 ⟸ XM_063282801 |
- Peptide Label: | isoform X5 |
- UniProtKB: | A0A8I5ZTP6 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063138875 ⟸ XM_063282805 |
- Peptide Label: | isoform X9 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-M0R484-F1-model_v2 | AlphaFold | M0R484 | 1-832 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13691006 | ||||||||
Promoter ID: | EPDNEW_R1529 | ||||||||
Type: | multiple initiation site | ||||||||
Name: | Afap1l2_2 | ||||||||
Description: | actin filament associated protein 1-like 2 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R1530 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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RGD ID: | 13691011 | ||||||||
Promoter ID: | EPDNEW_R1530 | ||||||||
Type: | single initiation site | ||||||||
Name: | Afap1l2_1 | ||||||||
Description: | actin filament associated protein 1-like 2 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Alternative Promoters: | null; see alsoEPDNEW_R1529 | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:1310668 | AgrOrtholog |
BioCyc Gene | G2FUF-55303 | BioCyc |
Ensembl Genes | ENSRNOG00000017164 | Ensembl, ENTREZGENE, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000023113.8 | UniProtKB/TrEMBL |
ENSRNOT00000073346 | ENTREZGENE | |
ENSRNOT00000073346.4 | UniProtKB/TrEMBL | |
ENSRNOT00000105824.1 | UniProtKB/TrEMBL | |
ENSRNOT00000109408.1 | UniProtKB/TrEMBL | |
ENSRNOT00000110011.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.30.29.30 | UniProtKB/TrEMBL |
InterPro | AFAP | UniProtKB/TrEMBL |
PH_like_dom | UniProtKB/TrEMBL | |
Pleckstrin_homology | UniProtKB/TrEMBL | |
KEGG Report | rno:292130 | UniProtKB/TrEMBL |
NCBI Gene | 292130 | ENTREZGENE |
PANTHER | PTHR14338 | UniProtKB/TrEMBL |
PTHR14338:SF4 | UniProtKB/TrEMBL | |
Pfam | PF00169 | UniProtKB/TrEMBL |
PhenoGen | Afap1l2 | PhenoGen |
PROSITE | PH_DOMAIN | UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000017164 | RatGTEx |
SMART | SM00233 | UniProtKB/TrEMBL |
Superfamily-SCOP | PH domain-like | UniProtKB/TrEMBL |
UniProt | A0A8I5ZSJ9_RAT | UniProtKB/TrEMBL |
A0A8I5ZTP6 | ENTREZGENE, UniProtKB/TrEMBL | |
A0A8I6ARV2 | ENTREZGENE, UniProtKB/TrEMBL | |
F1M5W8 | ENTREZGENE, UniProtKB/TrEMBL | |
M0R484 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2008-02-27 | Afap1l2 | actin filament associated protein 1-like 2 | RGD1310668_predicted | similar to expressed sequence AU041783 (predicted) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2005-01-20 | RGD1310668_predicted | similar to expressed sequence AU041783 (predicted) | LOC292130_predicted | Symbol and Name status set to approved | 1331353 | APPROVED | |
2005-01-12 | LOC292130_predicted | similar to expressed sequence AU041783 (predicted) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |