Ing3 (inhibitor of growth family, member 3)

Gene: Ing3 (inhibitor of growth family, member 3) Rattus norvegicus

Analyze

Symbol:

Ing3

Name:

inhibitor of growth family, member 3

RGD ID:

1310556

Description:

Predicted to enable histone H4 acetyltransferase activity and methylated histone binding activity. Predicted to contribute to histone H2A acetyltransferase activity and histone H4 acetyltransferase activity. Predicted to be involved in positive regulation of double-strand break repair via homologous recombination; regulation of DNA-templated transcription; and regulation of cell cycle. Predicted to be located in nucleoplasm. Predicted to be part of chromatin and piccolo histone acetyltransferase complex. Used to study hepatocellular carcinoma. Orthologous to human ING3 (inhibitor of growth family member 3); PARTICIPATES IN INO80 family mediated chromatin remodeling pathway; INTERACTS WITH (+)-schisandrin B; acrylamide; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

inhibitor of growth protein 3; LOC312154; MGC112729

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ING3 (inhibitor of growth family member 3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Ing3 (inhibitor of growth family, member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Ing3 (inhibitor of growth family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ING3 (inhibitor of growth family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ING3 (inhibitor of growth family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Ing3 (inhibitor of growth family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ING3 (inhibitor of growth family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ING3 (inhibitor of growth family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Ing3 (inhibitor of growth family member 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	BRME1 (break repair meiotic recombinase recruitment factor 1)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ING3 (inhibitor of growth family member 3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Ing3 (inhibitor of growth family, member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	ing3 (inhibitor of growth family, member 3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PHO23	Alliance	DIOPT (InParanoid\|OrthoInspector\|PANTHER)
Drosophila melanogaster (fruit fly):	Ing3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Caenorhabditis elegans (roundworm):	ing-3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	YNG2	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	ing3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	51,439,218 - 51,469,502 (+)	NCBI		GRCr8
mRatBN7.2	4	50,477,954 - 50,505,168 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	50,477,962 - 50,503,715 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	55,464,332 - 55,490,032 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	51,385,420 - 51,411,119 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	49,809,903 - 49,835,636 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	49,017,235 - 49,044,450 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	49,017,311 - 49,042,990 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	48,811,480 - 48,839,408 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	48,255,445 - 48,281,131 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	48,486,086 - 48,510,876 (+)	NCBI
Celera	4	45,685,074 - 45,710,769 (+)	NCBI		Celera
Cytogenetic Map	4	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

hepatocellular carcinoma (IDA)

pleomorphic xanthoastrocytoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-methylcholine (ISO)

acrylamide (EXP)

antimony(0) (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

cyclosporin A (ISO)

dibutyl phthalate (ISO)

dicrotophos (ISO)

dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

entinostat (ISO)

flutamide (EXP)

gentamycin (EXP)

irinotecan (ISO)

iron dichloride (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

p-chloromercuribenzoic acid (ISO)

paracetamol (ISO)

pentanal (ISO)

phenobarbital (ISO)

phenol (ISO)

pirinixic acid (ISO)

propanal (ISO)

resorcinol (ISO)

rotenone (ISO)

SB 431542 (ISO)

Soman (EXP)

sunitinib (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (ISO)

tetrachloromethane (EXP)

thalidomide (ISO)

thimerosal (ISO)

thioacetamide (EXP)

torcetrapib (ISO)

trichostatin A (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

chromatin organization (IEA)

chromatin remodeling (IEA)

positive regulation of double-strand break repair via homologous recombination (ISO)

regulation of cell cycle (ISO)

regulation of DNA-templated transcription (IBA,IEA)

Cellular Component

NuA4 histone acetyltransferase complex (IBA,IEA,ISO,ISS)

nucleoplasm (ISO)

nucleosome (ISO)

piccolo histone acetyltransferase complex (ISO,ISS)

Rpd3L complex (IEA)

Swr1 complex (ISO,ISS)

Molecular Function

histone acetyltransferase activity (IEA)

histone H2A acetyltransferase activity (ISO)

histone H4 acetyltransferase activity (ISO,ISS)

histone H4K12 acetyltransferase activity (ISO)

histone H4K16 acetyltransferase activity (ISO)

histone H4K5 acetyltransferase activity (ISO)

histone H4K8 acetyltransferase activity (ISO)

metal ion binding (IEA)

methylated histone binding (IBA,IEA,ISO)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

INO80 family mediated chromatin remodeling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Molecular mechanisms of Nano-selenium in mitigating hepatocellular carcinoma induced by N-nitrosodiethylamine (NDEA) in rats.	Ahmed HH, etal., Toxicol Mech Methods. 2014 Sep 4:1-10.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Comprehensive gene review and curation	RGD comprehensive gene curation
8.	The INO80 family of chromatin-remodeling enzymes: regulators of histone variant dynamics.	Watanabe S and Peterson CL, Cold Spring Harb Symp Quant Biol. 2010;75:35-42. doi: 10.1101/sqb.2010.75.063. Epub 2011 Apr 18.

Additional References at PubMed

PMID:12477932	PMID:14966270	PMID:16387653	PMID:16728974	PMID:19154204	PMID:24463511	PMID:25151306

Genomics

Comparative Map Data

Ing3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	4	51,439,218 - 51,469,502 (+)	NCBI		GRCr8
mRatBN7.2	4	50,477,954 - 50,505,168 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	4	50,477,962 - 50,503,715 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	4	55,464,332 - 55,490,032 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	4	51,385,420 - 51,411,119 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	4	49,809,903 - 49,835,636 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	4	49,017,235 - 49,044,450 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	4	49,017,311 - 49,042,990 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	4	48,811,480 - 48,839,408 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	4	48,255,445 - 48,281,131 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	4	48,486,086 - 48,510,876 (+)	NCBI
Celera	4	45,685,074 - 45,710,769 (+)	NCBI		Celera
Cytogenetic Map	4	q22	NCBI

ING3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	120,950,777 - 120,977,216 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	120,950,763 - 120,977,216 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	120,590,831 - 120,617,270 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	120,378,053 - 120,402,947 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	7	120,184,767 - 120,190,985	NCBI
Celera	7	115,400,338 - 115,425,232 (+)	NCBI		Celera
Cytogenetic Map	7	q31.31	NCBI
HuRef	7	114,954,042 - 114,978,936 (+)	NCBI		HuRef
CHM1_1	7	120,524,131 - 120,549,025 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	122,266,123 - 122,292,563 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	119,985,911 - 120,010,805 (+)	NCBI

Ing3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	6	21,948,002 - 21,976,037 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	6	21,949,570 - 21,976,037 (+)	Ensembl		GRCm39 Ensembl
GRCm38	6	21,949,571 - 21,976,038 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	6	21,949,571 - 21,976,038 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	6	21,899,615 - 21,926,037 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	6	21,899,647 - 21,926,038 (+)	NCBI		MGSCv36	mm8
Celera	6	22,003,416 - 22,030,061 (+)	NCBI		Celera
Cytogenetic Map	6	A3.1	NCBI
cM Map	6	8.81	NCBI

Ing3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955479	2,743,655 - 2,774,247 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955479	2,741,554 - 2,771,524 (+)	NCBI	ChiLan1.0	ChiLan1.0

ING3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	6	157,813,116 - 157,845,522 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	7	9,823,366 - 9,855,777 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	7	112,955,848 - 112,984,473 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	7	125,643,311 - 125,671,566 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	7	125,643,332 - 125,671,566 (+)	Ensembl	panpan1.1		panPan2

ING3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	14	59,067,282 - 59,093,399 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	14	59,067,351 - 59,092,976 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	14	58,484,146 - 58,510,211 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	14	59,103,110 - 59,129,175 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	14	59,103,023 - 59,129,160 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	14	59,197,279 - 59,223,360 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	14	58,820,372 - 58,846,379 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	14	59,199,020 - 59,225,088 (+)	NCBI		UU_Cfam_GSD_1.0

Ing3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	48,024,303 - 48,051,176 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936605	4,151,202 - 4,179,689 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936605	4,154,276 - 4,179,627 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ING3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	18	25,948,097 - 25,976,499 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	18	25,946,529 - 25,976,528 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	18	27,553,038 - 27,581,120 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ING3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	21	89,772,546 - 89,802,250 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	21	89,772,528 - 89,802,244 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666042	13,768,451 - 13,798,160 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ing3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624783	15,094,764 - 15,126,693 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624783	15,094,631 - 15,126,699 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ing3
121 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	470
Count of miRNA genes:	239
Interacting mature miRNAs:	307
Transcripts:	ENSRNOT00000007476
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
619616	Bp79	Blood pressure QTL 79		0.0292	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	4	5214602	78882945	Rat
2303168	Bp330	Blood pressure QTL 330	4.25	0.017	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	4	5214602	146446691	Rat
2302371	Stl22	Serum triglyceride level QTL 22	5.15		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	5218294	57114705	Rat
1358203	Stl19	Serum triglyceride level QTL 19	2.8	0.002	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	5218294	65958103	Rat
631642	Stl2	Serum triglyceride level QTL 2	3.3		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	4	5219178	56647776	Rat
6478724	Anxrr35	Anxiety related response QTL 35		0.00449	defecation behavior trait (VT:0010462)	defecation measurement (CMO:0000997)	4	10084089	55084089	Rat
6478766	Anxrr47	Anxiety related response QTL 47		0.09637	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	4	10084089	55084089	Rat
6478769	Anxrr48	Anxiety related response QTL 48		0.02514	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	4	10084089	55084089	Rat
8694374	Bw155	Body weight QTL 155	3.39	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	4	10084089	55084089	Rat
9590304	Scort17	Serum corticosterone level QTL 17	4.96	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	10084089	55084089	Rat
8552906	Pigfal3	Plasma insulin-like growth factor 1 level QTL 3			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	4	10084089	55084089	Rat
631261	Tcas3	Tongue tumor susceptibility QTL 3	6.88		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	4	10814170	91360527	Rat
2316958	Gluco58	Glucose level QTL 58	10		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	4	11320076	180699135	Rat
2303585	Bw86	Body weight QTL 86	4		body mass (VT:0001259)	body weight (CMO:0000012)	4	14678065	59678065	Rat
2313401	Anxrr27	Anxiety related response QTL 27			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	4	17933508	62933508	Rat
61412	Pia2	Pristane induced arthritis QTL 2	3.9		joint integrity trait (VT:0010548)	post-insult time to onset of experimental arthritis (CMO:0001450)	4	21333343	62278020	Rat
6909122	Insul22	Insulin level QTL 22	4.63		blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	4	26907285	75585128	Rat
6909128	Pancm4	Pancreatic morphology QTL 4	11.35		pancreas mass (VT:0010144)	pancreas wet weight (CMO:0000626)	4	26907285	75585128	Rat
8655906	Rf60	Renal function QTL 60	3.8		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	4	29494195	81006281	Rat
12798520	Anxrr55	Anxiety related response QTL 55	4.45	0.01	locomotor behavior trait (VT:0001392)	number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)	4	32583980	114627242	Rat
11530004	Niddm71	Non-insulin dependent diabetes mellitus QTL 71		0.001	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	4	32584199	52754138	Rat
8552782	Vie1	Viral induced encephalitis QTL 1	26.4		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
8552801	Bw143	Body weight QTL 143	7.3		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	4	34430484	82490359	Rat
8552809	Vie5	Viral induced encephalitis QTL 5	25.3		brain integrity trait (VT:0010579)	encephalitis incidence/prevalence measurement (CMO:0002361)	4	34430484	82490359	Rat
8655961	Kidm43	Kidney mass QTL 43	18		kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	4	36303261	103194984	Rat
1358352	Srcrt3	Stress Responsive Cort QTL 3	2.29		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	38465774	146803430	Rat
61475	Aia2	Adjuvant induced arthritis QTL 2	5.8		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	4	39505275	73892441	Rat
1331807	Rf31	Renal function QTL 31	2.988		urine potassium amount (VT:0010539)	urine potassium level (CMO:0000128)	4	39524264	74726312	Rat
1300139	Hrtrt6	Heart rate QTL 6	2.85		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	4	39524264	116179656	Rat
61445	Strs3	Sensitivity to stroke QTL 3	3		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	4	40433388	85433388	Rat
8694439	Bw168	Body weight QTL 168	9.57	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	4	40433414	85433414	Rat
6893678	Bw108	Body weight QTL 108	2.6	0.006	body mass (VT:0001259)	body weight (CMO:0000012)	4	43457976	88457976	Rat
1576305	Emca6	Estrogen-induced mammary cancer QTL 6	5.8		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	4	44463720	155883716	Rat
1354612	Foco1	Food consumption QTL 1	8.87		eating behavior trait (VT:0001431)	food intake rate (CMO:0000427)	4	44463908	148090542	Rat
1354660	Salc1	Saline consumption QTL 1	11.26		drinking behavior trait (VT:0001422)	saline drink intake rate (CMO:0001627)	4	44463908	148090542	Rat
2312567	Glom19	Glomerulus QTL 19	1.9	0.006	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	4	45456990	146803430	Rat
10450818	Scl76	Serum cholesterol level QTL 76	3.6	0.01	blood VLDL cholesterol amount (VT:0005144)	blood high density lipoprotein cholesterol level (CMO:0000052)	4	49178116	57114705	Rat
10450821	Scl77	Serum cholesterol level QTL 77	4.1	0.01	blood VLDL cholesterol amount (VT:0005144)	blood high density lipoprotein cholesterol level (CMO:0000052)	4	49178116	57114705	Rat
10450825	Scl78	Serum cholesterol level QTL 78	3.7	0.01	blood VLDL cholesterol amount (VT:0005144)	blood low density lipoprotein cholesterol level (CMO:0000053)	4	49178116	57114705	Rat
1298082	Stresp4	Stress response QTL 4			blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	4	50119848	146803430	Rat

Markers in Region

A005W09

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	50,503,109 - 50,503,262 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	49,042,392 - 49,042,544	NCBI	Rnor6.0
Rnor_5.0	4	48,837,350 - 48,837,502	UniSTS	Rnor5.0
RGSC_v3.4	4	48,280,526 - 48,280,678	UniSTS	RGSC3.4
Celera	4	45,710,164 - 45,710,316	UniSTS
Cytogenetic Map	4	q22	UniSTS

ING3-1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	50,495,855 - 50,496,645 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	49,035,138 - 49,035,927	NCBI	Rnor6.0
Rnor_5.0	4	48,830,096 - 48,830,885	UniSTS	Rnor5.0
RGSC_v3.4	4	48,273,272 - 48,274,061	UniSTS	RGSC3.4
Celera	4	45,702,910 - 45,703,699	UniSTS
Cytogenetic Map	4	q22	UniSTS

G20547

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	4	50,503,109 - 50,503,262 (+)	MAPPER	mRatBN7.2
Rnor_6.0	4	49,042,392 - 49,042,544	NCBI	Rnor6.0
Rnor_5.0	4	48,837,350 - 48,837,502	UniSTS	Rnor5.0
RGSC_v3.4	4	48,280,526 - 48,280,678	UniSTS	RGSC3.4
Celera	4	45,710,164 - 45,710,316	UniSTS
Cytogenetic Map	4	q22	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	2	18	15	8	18	8			66	20	39	10
Low	1	25	42	33	1	33	8	11	8	15	2	1	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001034107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236140	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006236141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039107508	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063285972	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC116288	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC100082	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473959	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ232896	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000004	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000007476 ⟹ ENSRNOP00000007476

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	50,477,962 - 50,503,715 (+)	Ensembl
Rnor_6.0 Ensembl	4	49,017,311 - 49,042,990 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104929 ⟹ ENSRNOP00000088161

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	4	50,478,039 - 50,503,715 (+)	Ensembl

RefSeq Acc Id:

NM_001034107 ⟹ NP_001029279

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	51,443,811 - 51,469,499 (+)	NCBI
mRatBN7.2	4	50,478,030 - 50,503,715 (+)	NCBI
Rnor_6.0	4	49,017,311 - 49,042,997 (+)	NCBI
Rnor_5.0	4	48,811,480 - 48,839,408 (+)	NCBI
RGSC_v3.4	4	48,255,445 - 48,281,131 (+)	RGD
Celera	4	45,685,074 - 45,710,769 (+)	RGD

Sequence:

show sequence

CTCCGGCGACAGCGAGTGACACAAATAAACCCCTGGACCCGTTCGTCTCCGCAGCACTCAGGGC
CGCGATGTTGTACCTAGAAGACTATTTGGAAATGATTGAGCAGCTTCCGATGGACCTGCGGGAC
CGCTTCACGGAGATGCGCGAGATGGATCTGCAGGTGCAGAATGCAATGGATCAACTAGAACAAA
GAGTCAGTGAATTCTTTATGAATGCAAAGAAGAATAAACCCGAGTGGCGAGAAGAACAGATGGC
ATCCATCAAAAAAGACTACTATAAAGCTTTGGAAGATGCAGATGAGAAAGTACAGTTGGCGAAC
CAAATTTATGATTTGGTAGATCGCCACTTGAGAAAGCTGGACCAGGAGCTGGCTAAGTTTAAAA
TGGAGCTGGAAGCTGATAATGCTGGAATTACGGAAATATTGGAGAGGCGATCTTTGGAATTAGA
TGCTCCTTCGCAGCCAGTGAACAATCACCACGCTCATTCACATACTCCTGTGGAAAAAAGGAAA
TATAATCCAACTTCTCACCATACAGCAACAGACCATATCCCCGAAAAGAAATTCAAATCCGAAG
CTCTCCTGTCCACCCTTACATCTGATGCTTCTAAGGAGAACACGCTGGGCTGTCGAAATAATAA
TTCCACAGCTTCCTGCAACAATGCTTACAATGTGAACTCGTCCCAACCCCTGGCATCCTACAAT
ATTGGTTCATTATCTTCAGGGGCTGGCGCAGGGGCCATCACCATGGCAGCAGCTCAGGCAGTGC
AAGCAACAGCACAGATGAAAGAAGGACGAAGAACATCGAGTTTAAAAGCCAGTTATGAAGCGTT
TAAGAATAATGACTTCCAGCTGGGAAAAGAATTCTCCATGCCCAGAGAGACAGCAGGCTATTCC
TCCTCGTCGGCACTCATGACAACCTTAACACAGAATGCCAGCTCCTCGGCCGCCGACTCTCGCA
GTGGCAGGAAGAGCAAAAATAACACCAAGTCTTCAAGCCAGCAGTCCTCCTCCTCATCCTCATC
CTCGTCCTCCTCCTCCTTATCTCTGTGTTCGTCATCTTCAACTGTAGTACAAGAAGTTTCCCAG
CAAACAACGGTAGTGCCCGAATCTGATTCCAACAGTCAGGTCGATTGGACTTACGACCCAAATG
AACCCCGGTATTGCATCTGTAATCAGGTATCCTATGGAGAGATGGTGGGATGTGATAACCAAGA
CTGTCCAATAGAGTGGTTCCACTATGGGTGTGTCGGCTTGACAGAAGCACCGAAGGGGAAGTGG
TTCTGTCCGCAGTGCACGGCTGCCATGAAGAGAAGAGGCAGTCGACACAAATAGAGAGGGGCTT
CACCGCAGGAAGGGAGAGCTTCAGCTCGGCATTTTATACGGGACTCTAGAAGGAACGACACGAG
GACGAAGAAACAACTCATTTCCAGGCGACCACTTAAAGGATTACATAGACAATCCTATAAGATC
TTGAACTTGAATTTTATGAGTTGTATTTTAATAATGTAAGTAAATTATTTATGCACTCCTGGTG
TGCTATGAATATTATTCCAGTTAGCCTTGGATTATTTCTGTGGCCAACATATGCAGACATTTGT
ACTCCTCAACCATTTTCTCAAAGTAATGGGCATTCTATAATTTAAACTTCAAAGAATTCCAACG
ATGAAGATTTTAAGAAAGAATTTTATATTCAACAGGTATATTCTGCTGCATGTACTGTACTCCA
GAGCTGTTATGTTACACTGTATATAAATGGTTGCAAAAAAAAAACAAAAAACAAAAAACAAACA
AAAAAAGTCAGTCCTTCGAAAAAGGATTAAGATAATGGTTTTTAAGATGCCTTTATAATAAGCT
TTGTTTCTTTGTGAAACTCATTCAGCAGGCTGAAGGGATTGGTTTATGTGATAAAGTGGGCTGA
GGTCCTCTAGAGTACCTGGGTACATAAACAGAAACTCCTGTAGGTAAACCCGATCCGTGCCATT
AGTCTACATGTTTCTGCATCCAGATAGAATGCCGCTCAAGCTCAAGGGGGTGGGGGTGGGGCCT
CTGGGGGAAAGGGCGTTAAAGTGATACATTTTTATACCAAATGTGTTTATTTTTTTGTGCGAGT
AATCCTTAAATTGGAATTGTATTAGGTGTTAAAATAAAGTTTTTTAAAAAAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006236140 ⟹ XP_006236202

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	51,439,218 - 51,469,502 (+)	NCBI
mRatBN7.2	4	50,477,954 - 50,505,168 (+)	NCBI
Rnor_6.0	4	49,017,235 - 49,044,450 (+)	NCBI
Rnor_5.0	4	48,811,480 - 48,839,408 (+)	NCBI

Sequence:

show sequence

TTTTTTTTTTTTTTTTTTCCTTTGCCGGAGTCGAGCGGGTGCTGCTAGCGGAGGCGCCATATTG
GAAGGGACAAAACTCCGGCGACAGCGAGTGACACAAATAAACCCCTGGACCCGTTCGTCTCCGC
AGCACTCAGGGCCGCGATGTTGTACCTAGAAGACTATTTGGAAATGATTGAGCAGCTTCCGATG
GACCTGCGGGACCGCTTCACGGAGATGCGCGAGATGGATCTGCAGGTGCAGAATGCAATGGATC
AACTAGAACAAAGAGTCAGTGAATTCTTTATGAATGCAAAGAAGAATAAACCCGAGTGGCGAGA
AGAACAGATGGCATCCATCAAAAAAGACTACTATAAAGCTTTGGAAGATGCAGATGAGAAAGTA
CAGTTGGCGAACCAAATTTATGATTTGGTAGATCGCCACTTGAGAAAGCTGGACCAGGAGCTGG
CTAAGTTTAAAATGGAGCTGGAAGCTGATAATGCTGGAATTACGGAAATATTGGAGAGGCGATC
TTTGGAATTAGATGCTCCTTCGCAGCCAGTGAACAATCACCACGCTCATTCACATACTCCTGTG
GAAACAACAGACCATATCCCCGAAAAGAAATTCAAATCCGAAGCTCTCCTGTCCACCCTTACAT
CTGATGCTTCTAAGGAGAACACGCTGGGCTGTCGAAATAATAATTCCACAGCTTCCTGCAACAA
TGCTTACAATGTGAACTCGTCCCAACCCCTGGCATCCTACAATATTGGTTCATTATCTTCAGGG
GCTGGCGCAGGGGCCATCACCATGGCAGCAGCTCAGGCAGTGCAAGCAACAGCACAGATGAAAG
AAGGACGAAGAACATCGAGTTTAAAAGCCAGTTATGAAGCGTTTAAGAATAATGACTTCCAGCT
GGGAAAAGAATTCTCCATGCCCAGAGAGACAGCAGGCTATTCCTCCTCGTCGGCACTCATGACA
ACCTTAACACAGAATGCCAGCTCCTCGGCCGCCGACTCTCGCAGTGGCAGGAAGAGCAAAAATA
ACACCAAGTCTTCAAGCCAGCAGTCCTCCTCCTCATCCTCATCCTCGTCCTCCTCCTCCTTATC
TCTGTGTTCGTCATCTTCAACTGTAGTACAAGAAGTTTCCCAGCAAACAACGGTAGTGCCCGAA
TCTGATTCCAACAGTCAGGTCGATTGGACTTACGACCCAAATGAACCCCGGTATTGCATCTGTA
ATCAGGTATCCTATGGAGAGATGGTGGGATGTGATAACCAAGACTGTCCAATAGAGTGGTTCCA
CTATGGGTGTGTCGGCTTGACAGAAGCACCGAAGGGGAAGTGGTTCTGTCCGCAGTGCACGGCT
GCCATGAAGAGAAGAGGCAGTCGACACAAATAGAGAGGGGCTTCACCGCAGGAAGGGAGAGCTT
CAGCTCGGCATTTTATACGGGACTCTAGAAGGAACGACACGAGGACGAAGAAACAACTCATTTC
CAGGCGACCACTTAAAGGATTACATAGACAATCCTATAAGATCTTGAACTTGAATTTTATGAGT
TGTATTTTAATAATGTAAGTAAATTATTTATGCACTCCTGGTGTGCTATGAATATTATTCCAGT
TAGCCTTGGATTATTTCTGTGGCCAACATATGCAGACATTTGTACTCCTCAACCATTTTCTCAA
AGTAATGGGCATTCTATAATTTAAACTTCAAAGAATTCCAACGATGAAGATTTTAAGAAAGAAT
TTTATATTCAACAGGTATATTCTGCTGCATGTACTGTACTCCAGAGCTGTTATGTTACACTGTA
TATAAATGGTTGCAAAAAAAAACAAAAAACAAAAAACAAACAAAAAAAGTCAGTCCTTCGAAAA
AGGATTAAGATAATGGTTTTTAAGATGCCTTTATAATAAGCTTTGTTTCTTTGTGAAACTCATT
CAGCAGGCTGAAGGGATTGGTTTATGTGATAAAGTGGGCTGAGGTCCTCTAGAGTACCTGGGTA
CATAAACAGAAACTCCTGTAGGTAAACCCGATCCGTGCCATTAGTCTACATGTTTCTGCATCCA
GATAGAATGCCGCTCAAGCTCAAGGGGGTGGGGGTGGGGCCTCTGGGGGAAAGGGCGTTAAAGT
GATACATTTTTATACCAAATGTGTTTATTTTTTTGTGCGAGTAATCCTTAAATTGGAATTGTAT
TAGGTGTTAAAATAAAGTTTTTTAAAAAAATAACTTGTATTTATACTTTACACACTTAATTATG
AAAATTTCTTAATTGCAATTTATTTCTAATTTTCATAATCGAAAAAGGTTAGAGGTTAGCATGC
AGAATGCTATGTAATCTATGATTTCTATAATAATGGTTGGAAATTGTGCTATGAGGATAAGGAA
AGAACATTTTAAATGTAAATTTGAAGTGTCAAATGTATTTTTCTAGAATATTTCTCTGGCTTTG
CTTTGAATCTAAGGGATATAAAAAGAACCTAATTACAGCAGATATAATGAAAATCATGGCTATA
GATGTTTGGACTGGAAGCAGTGTGGCCAGTATGATTTAAAGAGACCTTAAAATACAGTTCTGTT
TTTAATTCTGTGACATCGTGATGTGGCAGTTAATTAACTCTTAAATCACTCTGGGCTTTGTGAA
ACCAAGGCAATGCAGGTTTCCAAGCACTCCTACTGTGCGTGCAGTTTAGGCGATGGACTTCACA
TCGTGGAGGCTTCACTTAATAAAAGTTCAGTGGATGGGTAGAAAAATTGATGAAACCTCAAAGA
TCAGACTTCTCAATATTGGAATATATGAAATCCATCAGACTTGTGCTTTAATGAAGCCCACTTC
TGAATCTTTTAGAATGTACTCAAAAGGCAGTGTTAAATCTATGTAATGCTACCTAAAGGGTAGA
GATTTGACAGATTTTAGGAGCCTCATCTTGCTGTAAGATCCTGGAATGCTGAATTGACACAGGC
TTACTTTATAACTTTTGTCAGCCCCAAAGACGGGTTCATACAGTCCTTAGGATTTAATATCATC
AAGAGTGTGATGATTTCACAGTATTTTGTAAGCCTCTAAGCAATGTATACAGTTGTTCTGTTAG
CTCTGGAGATGCTTGGATGAGAGGCGTTTATAGGCTTACACACAGTCACACAATGTGACTCTTC
TAAAGTCATCCACCCTGAGAGCTATCTAGAGGACATCACCTTATTTGTTGAGTCAGGAACATTC
CTATATTGAGTCCCTACAGCTCCTCTCTCTCTGCTGTACTTAAGAGTCTCTTAGAAAGAAAACA
AGGTAGCAAGCTTTGAGCTCAAACATTGACTCTCTTACAAACTATATATAAAGAAAGTATATAC
ACCAAAATTTTACATTAAATACTTAGAACTGAGTAGAACCTGTTACTAAATGAGATAGAGATGT
ATATACGTACATACCATATATTAGCAAACATGGAACTACCTCACTAAAGCAGTCCTTCCAGCAT
TAATATAATACACTTGTTGCATTTACACCAAGACATTCAGAGTCTTTGTTGTACAAAACTTCTG
TAACAGTGGGTGGCATAAAAGGCCCACGTGTGAGTTTGCAGTTTATAGGTGGGGAAAAATGAGG
CCTTACTGCTGTAGTGTATATTTAAATGTTCATGGTAACACATTTGAAGCAATAAATGGCTTAA
TTAAATTCCTA

hide sequence

RefSeq Acc Id:

XM_006236141 ⟹ XP_006236203

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	51,439,218 - 51,469,502 (+)	NCBI
mRatBN7.2	4	50,477,954 - 50,505,168 (+)	NCBI
Rnor_6.0	4	49,017,235 - 49,044,450 (+)	NCBI
Rnor_5.0	4	48,811,480 - 48,839,408 (+)	NCBI

Sequence:

show sequence

TTTTTTTTTTTTTTTTTTCCTTTGCCGGAGTCGAGCGGGTGCTGCTAGCGGAGGCGCCATATTG
GAAGGGACAAAACTCCGGCGACAGCGAGTGACACAAATAAACCCCTGGACCCGTTCGTCTCCGC
AGCACTCAGGGCCGCGATGTTGTACCTAGAAGACTATTTGGAAAATGCAATGGATCAACTAGAA
CAAAGAGTCAGTGAATTCTTTATGAATGCAAAGAAGAATAAACCCGAGTGGCGAGAAGAACAGA
TGGCATCCATCAAAAAAGACTACTATAAAGCTTTGGAAGATGCAGATGAGAAAGTACAGTTGGC
GAACCAAATTTATGATTTGGTAGATCGCCACTTGAGAAAGCTGGACCAGGAGCTGGCTAAGTTT
AAAATGGAGCTGGAAGCTGATAATGCTGGAATTACGGAAATATTGGAGAGGCGATCTTTGGAAT
TAGATGCTCCTTCGCAGCCAGTGAACAATCACCACGCTCATTCACATACTCCTGTGGAAAAAAG
GAAATATAATCCAACTTCTCACCATACAGCAACAGACCATATCCCCGAAAAGAAATTCAAATCC
GAAGCTCTCCTGTCCACCCTTACATCTGATGCTTCTAAGGAGAACACGCTGGGCTGTCGAAATA
ATAATTCCACAGCTTCCTGCAACAATGCTTACAATGTGAACTCGTCCCAACCCCTGGCATCCTA
CAATATTGGTTCATTATCTTCAGGGGCTGGCGCAGGGGCCATCACCATGGCAGCAGCTCAGGCA
GTGCAAGCAACAGCACAGATGAAAGAAGGACGAAGAACATCGAGTTTAAAAGCCAGTTATGAAG
CGTTTAAGAATAATGACTTCCAGCTGGGAAAAGAATTCTCCATGCCCAGAGAGACAGCAGGCTA
TTCCTCCTCGTCGGCACTCATGACAACCTTAACACAGAATGCCAGCTCCTCGGCCGCCGACTCT
CGCAGTGGCAGGAAGAGCAAAAATAACACCAAGTCTTCAAGCCAGCAGTCCTCCTCCTCATCCT
CATCCTCGTCCTCCTCCTCCTTATCTCTGTGTTCGTCATCTTCAACTGTAGTACAAGAAGTTTC
CCAGCAAACAACGGTAGTGCCCGAATCTGATTCCAACAGTCAGGTCGATTGGACTTACGACCCA
AATGAACCCCGGTATTGCATCTGTAATCAGGTATCCTATGGAGAGATGGTGGGATGTGATAACC
AAGACTGTCCAATAGAGTGGTTCCACTATGGGTGTGTCGGCTTGACAGAAGCACCGAAGGGGAA
GTGGTTCTGTCCGCAGTGCACGGCTGCCATGAAGAGAAGAGGCAGTCGACACAAATAGAGAGGG
GCTTCACCGCAGGAAGGGAGAGCTTCAGCTCGGCATTTTATACGGGACTCTAGAAGGAACGACA
CGAGGACGAAGAAACAACTCATTTCCAGGCGACCACTTAAAGGATTACATAGACAATCCTATAA
GATCTTGAACTTGAATTTTATGAGTTGTATTTTAATAATGTAAGTAAATTATTTATGCACTCCT
GGTGTGCTATGAATATTATTCCAGTTAGCCTTGGATTATTTCTGTGGCCAACATATGCAGACAT
TTGTACTCCTCAACCATTTTCTCAAAGTAATGGGCATTCTATAATTTAAACTTCAAAGAATTCC
AACGATGAAGATTTTAAGAAAGAATTTTATATTCAACAGGTATATTCTGCTGCATGTACTGTAC
TCCAGAGCTGTTATGTTACACTGTATATAAATGGTTGCAAAAAAAAACAAAAAACAAAAAACAA
ACAAAAAAAGTCAGTCCTTCGAAAAAGGATTAAGATAATGGTTTTTAAGATGCCTTTATAATAA
GCTTTGTTTCTTTGTGAAACTCATTCAGCAGGCTGAAGGGATTGGTTTATGTGATAAAGTGGGC
TGAGGTCCTCTAGAGTACCTGGGTACATAAACAGAAACTCCTGTAGGTAAACCCGATCCGTGCC
ATTAGTCTACATGTTTCTGCATCCAGATAGAATGCCGCTCAAGCTCAAGGGGGTGGGGGTGGGG
CCTCTGGGGGAAAGGGCGTTAAAGTGATACATTTTTATACCAAATGTGTTTATTTTTTTGTGCG
AGTAATCCTTAAATTGGAATTGTATTAGGTGTTAAAATAAAGTTTTTTAAAAAAATAACTTGTA
TTTATACTTTACACACTTAATTATGAAAATTTCTTAATTGCAATTTATTTCTAATTTTCATAAT
CGAAAAAGGTTAGAGGTTAGCATGCAGAATGCTATGTAATCTATGATTTCTATAATAATGGTTG
GAAATTGTGCTATGAGGATAAGGAAAGAACATTTTAAATGTAAATTTGAAGTGTCAAATGTATT
TTTCTAGAATATTTCTCTGGCTTTGCTTTGAATCTAAGGGATATAAAAAGAACCTAATTACAGC
AGATATAATGAAAATCATGGCTATAGATGTTTGGACTGGAAGCAGTGTGGCCAGTATGATTTAA
AGAGACCTTAAAATACAGTTCTGTTTTTAATTCTGTGACATCGTGATGTGGCAGTTAATTAACT
CTTAAATCACTCTGGGCTTTGTGAAACCAAGGCAATGCAGGTTTCCAAGCACTCCTACTGTGCG
TGCAGTTTAGGCGATGGACTTCACATCGTGGAGGCTTCACTTAATAAAAGTTCAGTGGATGGGT
AGAAAAATTGATGAAACCTCAAAGATCAGACTTCTCAATATTGGAATATATGAAATCCATCAGA
CTTGTGCTTTAATGAAGCCCACTTCTGAATCTTTTAGAATGTACTCAAAAGGCAGTGTTAAATC
TATGTAATGCTACCTAAAGGGTAGAGATTTGACAGATTTTAGGAGCCTCATCTTGCTGTAAGAT
CCTGGAATGCTGAATTGACACAGGCTTACTTTATAACTTTTGTCAGCCCCAAAGACGGGTTCAT
ACAGTCCTTAGGATTTAATATCATCAAGAGTGTGATGATTTCACAGTATTTTGTAAGCCTCTAA
GCAATGTATACAGTTGTTCTGTTAGCTCTGGAGATGCTTGGATGAGAGGCGTTTATAGGCTTAC
ACACAGTCACACAATGTGACTCTTCTAAAGTCATCCACCCTGAGAGCTATCTAGAGGACATCAC
CTTATTTGTTGAGTCAGGAACATTCCTATATTGAGTCCCTACAGCTCCTCTCTCTCTGCTGTAC
TTAAGAGTCTCTTAGAAAGAAAACAAGGTAGCAAGCTTTGAGCTCAAACATTGACTCTCTTACA
AACTATATATAAAGAAAGTATATACACCAAAATTTTACATTAAATACTTAGAACTGAGTAGAAC
CTGTTACTAAATGAGATAGAGATGTATATACGTACATACCATATATTAGCAAACATGGAACTAC
CTCACTAAAGCAGTCCTTCCAGCATTAATATAATACACTTGTTGCATTTACACCAAGACATTCA
GAGTCTTTGTTGTACAAAACTTCTGTAACAGTGGGTGGCATAAAAGGCCCACGTGTGAGTTTGC
AGTTTATAGGTGGGGAAAAATGAGGCCTTACTGCTGTAGTGTATATTTAAATGTTCATGGTAAC
ACATTTGAAGCAATAAATGGCTTAATTAAATTCCTA

hide sequence

RefSeq Acc Id:

XM_039107508 ⟹ XP_038963436

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	51,444,243 - 51,469,502 (+)	NCBI
mRatBN7.2	4	50,478,462 - 50,505,168 (+)	NCBI

RefSeq Acc Id:

XM_063285972 ⟹ XP_063142042

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	4	51,443,720 - 51,469,502 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001029279	(Get FASTA)	NCBI Sequence Viewer
	XP_006236202	(Get FASTA)	NCBI Sequence Viewer
	XP_006236203	(Get FASTA)	NCBI Sequence Viewer
	XP_038963436	(Get FASTA)	NCBI Sequence Viewer
	XP_063142042	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI00083	(Get FASTA)	NCBI Sequence Viewer
	EDM15141	(Get FASTA)	NCBI Sequence Viewer
	EDM15142	(Get FASTA)	NCBI Sequence Viewer
	EDM15143	(Get FASTA)	NCBI Sequence Viewer
	EDM15144	(Get FASTA)	NCBI Sequence Viewer
	EDM15145	(Get FASTA)	NCBI Sequence Viewer
	EDM15146	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000007476
	ENSRNOP00000007476.4
	ENSRNOP00000088161
	ENSRNOP00000088161.1
	ENSRNOP00055029406
	ENSRNOP00060027951
	ENSRNOP00065008713
GenBank Protein	Q498T3	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001029279 ⟸ NM_001034107

- UniProtKB:

Q498T3 (UniProtKB/Swiss-Prot), A0A8I6A977 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQMAS
IKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDA
PSQPVNNHHAHSHTPVEKRKYNPTSHHTATDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNS
TASCNNAYNVNSSQPLASYNIGSLSSGAGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFK
NNDFQLGKEFSMPRETAGYSSSSALMTTLTQNASSSAADSRSGRKSKNNTKSSSQQSSSSSSSS
SSSSLSLCSSSSTVVQEVSQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDC
PIEWFHYGCVGLTEAPKGKWFCPQCTAAMKRRGSRHK

hide sequence

RefSeq Acc Id:	XP_006236202 ⟸ XM_006236140
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6A977 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLYLEDYLEMIEQLPMDLRDRFTEMREMDLQVQNAMDQLEQRVSEFFMNAKKNKPEWREEQMAS IKKDYYKALEDADEKVQLANQIYDLVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDA PSQPVNNHHAHSHTPVETTDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASCNNAYNVN SSQPLASYNIGSLSSGAGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFS MPRETAGYSSSSALMTTLTQNASSSAADSRSGRKSKNNTKSSSQQSSSSSSSSSSSSLSLCSSS STVVQEVSQQTTVVPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVG LTEAPKGKWFCPQCTAAMKRRGSRHK hide sequence

RefSeq Acc Id:	XP_006236203 ⟸ XM_006236141
- Peptide Label:	isoform X2
- UniProtKB:	A6IE55 (UniProtKB/TrEMBL), A0A8I6A977 (UniProtKB/TrEMBL)
- Sequence:	show sequence MLYLEDYLENAMDQLEQRVSEFFMNAKKNKPEWREEQMASIKKDYYKALEDADEKVQLANQIYD LVDRHLRKLDQELAKFKMELEADNAGITEILERRSLELDAPSQPVNNHHAHSHTPVEKRKYNPT SHHTATDHIPEKKFKSEALLSTLTSDASKENTLGCRNNNSTASCNNAYNVNSSQPLASYNIGSL SSGAGAGAITMAAAQAVQATAQMKEGRRTSSLKASYEAFKNNDFQLGKEFSMPRETAGYSSSSA LMTTLTQNASSSAADSRSGRKSKNNTKSSSQQSSSSSSSSSSSSLSLCSSSSTVVQEVSQQTTV VPESDSNSQVDWTYDPNEPRYCICNQVSYGEMVGCDNQDCPIEWFHYGCVGLTEAPKGKWFCPQ CTAAMKRRGSRHK hide sequence

RefSeq Acc Id:

ENSRNOP00000007476 ⟸ ENSRNOT00000007476

RefSeq Acc Id:	XP_038963436 ⟸ XM_039107508
- Peptide Label:	isoform X4
- UniProtKB:	A0A8I6A977 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000088161 ⟸ ENSRNOT00000104929

RefSeq Acc Id:	XP_063142042 ⟸ XM_063285972
- Peptide Label:	isoform X3

Protein Domains

Inhibitor of growth protein N-terminal histone- PHD-type

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q498T3-F1-model_v2	AlphaFold	Q498T3	1-421	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13692898

Promoter ID:

EPDNEW_R3422

Type:

multiple initiation site

Name:

Ing3_1

Description:

inhibitor of growth family, member 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	4	49,017,254 - 49,017,314	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310556	AgrOrtholog
BioCyc Gene	G2FUF-45510	BioCyc
Ensembl Genes	ENSRNOG00000005496	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055021181	UniProtKB/Swiss-Prot
	ENSRNOG00060019752	UniProtKB/Swiss-Prot
	ENSRNOG00065007632	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000007476	ENTREZGENE
	ENSRNOT00000007476.6	UniProtKB/Swiss-Prot
	ENSRNOT00000104929.1	UniProtKB/TrEMBL
	ENSRNOT00055036195	UniProtKB/Swiss-Prot
	ENSRNOT00060034111	UniProtKB/Swiss-Prot
	ENSRNOT00065011950	UniProtKB/Swiss-Prot
Gene3D-CATH	3.30.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	6.10.140.1740	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7385392	IMAGE-MGC_LOAD
InterPro	ING3_PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ING_fam	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ING_N_histone-binding	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
	Zinc_finger_PHD-type_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_FYVE_PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_PHD-finger	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Znf_RING/FYVE/PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:312154	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:112729	IMAGE-MGC_LOAD
NCBI Gene	312154	ENTREZGENE
PANTHER	INHIBITOR OF GROWTH PROTEIN 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR10333	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	ING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ing3	PhenoGen
PROSITE	ZF_PHD_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ZF_PHD_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000005496	RatGTEx
	ENSRNOG00055021181	RatGTEx
	ENSRNOG00060019752	RatGTEx
	ENSRNOG00065007632	RatGTEx
SMART	ING	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PHD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF57903	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6A977	ENTREZGENE, UniProtKB/TrEMBL
	A6IE55	ENTREZGENE, UniProtKB/TrEMBL
	A6IE56_RAT	UniProtKB/TrEMBL
	A6IE57_RAT	UniProtKB/TrEMBL
	A6IE58_RAT	UniProtKB/TrEMBL
	A6IE59_RAT	UniProtKB/TrEMBL
	ING3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Ing3	inhibitor of growth family, member 3	Ing3_predicted	inhibitor of growth family, member 3 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Ing3_predicted	inhibitor of growth family, member 3 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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