Mpv17 (mitochondrial inner membrane protein MPV17)

Gene: Mpv17 (mitochondrial inner membrane protein MPV17) Rattus norvegicus

Analyze

Symbol:

Mpv17

Name:

mitochondrial inner membrane protein MPV17

RGD ID:

1310512

Description:

Predicted to enable channel activity. Predicted to be involved in several processes, including cellular response to reactive oxygen species; glomerular basement membrane development; and regulation of mitochondrial DNA metabolic process. Predicted to act upstream of or within reactive oxygen species metabolic process and sensory perception of sound. Predicted to be located in mitochondrial inner membrane and peroxisome. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2EE and mitochondrial DNA depletion syndrome 6. Orthologous to human MPV17 (mitochondrial inner membrane protein MPV17); INTERACTS WITH atrazine; bisphenol A; paracetamol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC360463; MpV17 mitochondrial inner membrane protein; MPV17 mitochondrial membrane protein-like; Mpv17 transgene, kidney disease mutant-like; Mpv17l

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	30,941,693 - 30,956,389 (+)	NCBI		GRCr8
mRatBN7.2	6	25,221,668 - 25,236,241 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	25,222,896 - 25,236,244 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	25,523,972 - 25,537,065 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	25,839,865 - 25,852,958 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	25,318,528 - 25,331,843 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	26,585,713 - 26,600,265 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	26,587,443 - 26,599,511 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	36,403,896 - 36,416,645 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	25,200,452 - 25,214,909 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	1,655,564 - 1,672,677 (+)	NCBI
Celera	6	24,714,225 - 24,727,365 (+)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autosomal recessive Alport syndrome (ISS)

Charcot-Marie-Tooth disease type 2EE (ISO)

cochlear disease (ISO)

Deoxyguanosine Kinase Deficiency (ISO)

focal segmental glomerulosclerosis (ISO)

genetic disease (ISO)

mitochondrial DNA depletion syndrome (ISO)

mitochondrial DNA depletion syndrome 15 (ISO)

mitochondrial DNA depletion syndrome 3 (ISS)

mitochondrial DNA depletion syndrome 6 (ISO)

mitochondrial metabolism disease (ISO)

nephrotic syndrome (ISS)

pigmentation disease (ISO)

proteinuria (ISO)

Tatton-Brown-Rahman syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

4,4'-sulfonyldiphenol (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

antirheumatic drug (ISO)

atrazine (EXP)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

cadmium sulfide (ISO)

carbon nanotube (ISO)

cerium trichloride (ISO)

cyclosporin A (ISO)

D-glucose (ISO)

doxorubicin (ISO)

elemental selenium (ISO)

ethanol (ISO)

fenthion (ISO)

folic acid (ISO)

fulvestrant (ISO)

glucose (ISO)

methidathion (ISO)

methylmercury chloride (ISO)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctane-1-sulfonic acid (ISO)

selenium atom (ISO)

sunitinib (ISO)

Testosterone propionate (ISO)

tetrachloromethane (ISO)

thioacetamide (EXP)

trichloroethene (EXP)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to reactive oxygen species (IEA,ISO)

glomerular basement membrane development (ISO)

homeostatic process (IEA,ISO)

inner ear development (ISO)

mitochondrial genome maintenance (IEA,ISO)

reactive oxygen species metabolic process (ISO)

regulation of mitochondrial DNA metabolic process (IBA,IEA,ISO,ISS)

regulation of reactive oxygen species metabolic process (ISO)

sensory perception of sound (ISO)

transmembrane transport (IEA)

Cellular Component

cytoplasm (IBA)

membrane (IEA)

mitochondrial inner membrane (IEA,ISO)

mitochondrion (IBA,IEA,ISO)

peroxisome (ISO)

Molecular Function

channel activity (IBA,IEA,ISO,ISS)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:7957077	PMID:12477932	PMID:16041630	PMID:16582910	PMID:18614015	PMID:25861990	PMID:26123482	PMID:26760297

Genomics

Comparative Map Data

Mpv17
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	30,941,693 - 30,956,389 (+)	NCBI		GRCr8
mRatBN7.2	6	25,221,668 - 25,236,241 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	25,222,896 - 25,236,244 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	25,523,972 - 25,537,065 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	25,839,865 - 25,852,958 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	25,318,528 - 25,331,843 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	26,585,713 - 26,600,265 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	26,587,443 - 26,599,511 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	36,403,896 - 36,416,645 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	25,200,452 - 25,214,909 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	1,655,564 - 1,672,677 (+)	NCBI
Celera	6	24,714,225 - 24,727,365 (+)	NCBI		Celera
Cytogenetic Map	6	q14	NCBI

MPV17
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	2	27,309,492 - 27,323,097 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	2	27,309,492 - 27,325,680 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	2	27,532,360 - 27,545,964 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	2	27,385,864 - 27,399,473 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	2	27,444,012 - 27,457,082	NCBI
Celera	2	27,379,464 - 27,393,076 (-)	NCBI		Celera
Cytogenetic Map	2	p23.3	NCBI
HuRef	2	27,274,582 - 27,288,152 (-)	NCBI		HuRef
CHM1_1	2	27,462,306 - 27,475,919 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	2	27,351,915 - 27,365,520 (-)	NCBI		T2T-CHM13v2.0

Mpv17
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	31,298,007 - 31,311,595 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	31,297,998 - 31,311,595 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	31,140,663 - 31,154,251 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	31,140,654 - 31,154,251 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	31,443,033 - 31,456,615 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	31,417,529 - 31,430,812 (-)	NCBI		MGSCv36	mm8
Celera	5	28,619,571 - 28,633,245 (-)	NCBI		Celera
Cytogenetic Map	5	B1	NCBI
cM Map	5	17.12	NCBI

Mpv17
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955469	9,279,540 - 9,291,954 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955469	9,279,540 - 9,292,012 (-)	NCBI	ChiLan1.0	ChiLan1.0

MPV17
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	12	99,189,334 - 99,202,979 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	2A	99,193,303 - 99,206,947 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	2A	27,311,551 - 27,325,249 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	2A	27,399,258 - 27,412,747 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	2A	27,399,258 - 27,414,090 (-)	Ensembl	panpan1.1		panPan2

MPV17
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	21,280,523 - 21,290,967 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	17	21,281,361 - 21,290,339 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	21,172,324 - 21,182,712 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	21,601,802 - 21,612,194 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	17	21,601,804 - 21,612,150 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	17	21,288,497 - 21,298,885 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	21,297,995 - 21,308,610 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	17	21,346,222 - 21,356,615 (-)	NCBI		UU_Cfam_GSD_1.0

Mpv17
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024406292	65,580,429 - 65,593,085 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936493	5,248,059 - 5,258,147 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936493	5,246,803 - 5,258,147 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MPV17
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	3	111,821,690 - 111,833,928 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	3	111,823,075 - 111,833,929 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1

MPV17
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	14	80,289,285 - 80,302,838 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666045	31,849,129 - 31,863,229 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Mpv17
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624738	9,395,416 - 9,407,223 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624738	9,395,315 - 9,411,904 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Mpv17
74 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	34
Count of miRNA genes:	31
Interacting mature miRNAs:	34
Transcripts:	ENSRNOT00000034207
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738023	Alc17	Alcohol consumption QTL 17	3.1	0.003	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	6	1	27574569	Rat
1354616	Despr12	Despair related QTL 12		0.0012	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	6	1	27574569	Rat
1549905	Stresp10	Stress response QTL 10	6.83	0.0066	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	6	1	27574569	Rat
2300176	Bmd51	Bone mineral density QTL 51	11.7	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	6	1	27574569	Rat
2300190	Bmd52	Bone mineral density QTL 52	11.2	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	6	1	27574569	Rat
1331743	Uae28	Urinary albumin excretion QTL 28	4.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	1	34235784	Rat
1578758	Tcas9	Tongue tumor susceptibility QTL 9	3.29		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	6	1	37618905	Rat
1598843	Cm63	Cardiac mass QTL 63	2.6		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	1	39036266	Rat
7411603	Foco13	Food consumption QTL 13	5.5	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	41223769	Rat
8552962	Pigfal16	Plasma insulin-like growth factor 1 level QTL 16	9.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	6	1	41223769	Rat
7411542	Bw127	Body weight QTL 127	5.5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	1	41223769	Rat
9589129	Insul24	Insulin level QTL 24	19.06	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	6	1	41223769	Rat
9589048	Scfw3	Subcutaneous fat weight QTL 3	4.57	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	6	1	41223769	Rat
2293709	Bss23	Bone structure and strength QTL 23	5.18	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	6	1	42487980	Rat
2293650	Bss31	Bone structure and strength QTL 31	5.05	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	6	1	42487980	Rat
2293656	Bss28	Bone structure and strength QTL 28	6.79	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	6	1	42487980	Rat
7411584	Foco4	Food consumption QTL 4	4.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	6	1	42838846	Rat
738024	Sach5	Saccharine consumption QTL 5	3.9	0.00039	consumption behavior trait (VT:0002069)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	6	1	43394190	Rat
2301972	Bp325	Blood pressure QTL 325	4.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	1	72227641	Rat
1300128	Rf16	Renal function QTL 16	3.89		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	34434305	Rat
1300164	Rf15	Renal function QTL 15	3.12		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	5074497	54641141	Rat
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
1578665	Bss16	Bone structure and strength QTL 16	4.4		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	6	11735669	72593685	Rat
1578668	Bmd14	Bone mineral density QTL 14	3.8		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	6	11735669	72593685	Rat
10401812	Kidm54	Kidney mass QTL 54			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	14368788	59368788	Rat
10401800	Kidm49	Kidney mass QTL 49			kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	6	14368788	59368788	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	15107216	107351382	Rat
1359023	Bp272	Blood pressure QTL 272	2.5		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	16536140	27261739	Rat
2292589	Emca10	Estrogen-induced mammary cancer QTL 10		0.048	mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	6	16536140	61536140	Rat
1354664	Slep2	Serum leptin concentration QTL 2	4.49		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	6	16536140	71636405	Rat
1641898	Colcr4	Colorectal carcinoma resistance QTL4	3.71	0.0007	intestine integrity trait (VT:0010554)	well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)	6	20338777	62613667	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	7	10	74	35	39	11	7
Low							1	1			2		1
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001098240	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764515	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764516	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764517	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008764519	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594206	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594208	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594209	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594210	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594211	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017594212	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112437	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112438	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112439	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112440	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112441	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112443	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112444	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039112445	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262038	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262039	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262040	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063262043	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC091193	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000034207 ⟹ ENSRNOP00000037647

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	25,222,896 - 25,232,622 (+)	Ensembl
Rnor_6.0 Ensembl	6	26,587,443 - 26,599,511 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000095043 ⟹ ENSRNOP00000079234

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	25,222,896 - 25,235,539 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000099208 ⟹ ENSRNOP00000091585

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	25,222,968 - 25,236,244 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000102606 ⟹ ENSRNOP00000092589

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	25,222,968 - 25,236,244 (+)	Ensembl

RefSeq Acc Id:

NM_001098240 ⟹ NP_001091710

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,943,110 - 30,956,207 (+)	NCBI
mRatBN7.2	6	25,223,143 - 25,236,241 (+)	NCBI
Rnor_6.0	6	26,587,192 - 26,600,265 (+)	NCBI
Rnor_5.0	6	36,403,896 - 36,416,645 (+)	NCBI
RGSC_v3.4	6	25,200,452 - 25,214,909 (+)	RGD
Celera	6	24,714,225 - 24,727,365 (+)	RGD

Sequence:

show sequence

GTGTTTACTTGGGGGGTGGAACCCAGGCTCTGACCTCATGAGTTTCTGGATTAGGACTGGATGC
CTTACTGCTGCTTCTCCAGTTGTATAGTGACCACGAGGCAGGAACGCGGCCCAGTAAGCAACTT
TTCTGCGGCCTCTGTCATTTGCAGATTTTGGAAGTAGGGCGAGTGAGGATAAGGAAGTGGCAGG
CATGTTCTTTACTGTGAGGTGCAGTGGGAGTGACTTCTCCTCTTGGTTTGACAGGAGGCATGGC
ACTCTGGCGAGCATACCAGAGGGCCCTGGCTGCACATCCGTGGAAAGTCCAGGTTCTGACAGCT
GGGTCACTGATGGGCCTAGGTGACATTATCTCACAGCAGCTGGTGGAAAGGCGGGGTCTCCAGC
AACACCAGACTGGCCGGACCTTGACCATGGCATCCCTTGGCTGTGGCTTTGTGGGCCCTGTGGT
CGGAGGCTGGTACAGGGTTTTGGACCACTTAATCCCCGGCACCACCAAGGTGAATGCACTCAAG
AAGATGTTGTTAGATCAGGGGGGCTTTGCCCCATGTTTCCTTGGCTGCTTTCTCCCACTGGTAG
GGGTACTCAATGGAATGTCAGCCCAGGACAATTGGGCCAAACTGAAGCGGGACTACCCCGACGC
CCTCATCACCAACTACTATCTCTGGCCTGCTGTGCAGTTAGCCAACTTCTACCTGGTCCCCCTG
CATTACAGGTTGGCTGTTGTCCAGTGCGTTGCTGTTGTCTGGAACTCCTACCTGTCCTGGAAGG
CACATCAGCTCTAAGCCTGCCCTGTTCCGTGGTTCGCACCTTGCACTGCTGCTCCGTGGCCCTC
TAATGCTTGGACAGCTTCTTCCAACTGAGCACAACAGGACTGGAGAGGTGGCTCAGCCGTTAGA
GCATGGACTGACTGCTCTATAGGAGACCTAAGTTTGGTTCCAAACACCCACATCGGGTAGCTCA
CACCTCCGTGTCTCAAGCTCCAGGAGATCTGATGTCCTCTTCTGGCCTCTGAAGCACCTGCACT
CACATGTACATATCAACACATAGACACATTCGTAATTAAGCACACAATGAAATCTTTTTTTTTT
TTGGGTTCTTTTTTTCGGAGCTGGGGACCGAACCCAGGGCCTTGCGCTTCCTAGGTAAGCGCTC
TACCACTGAGCTAAATCCCCAGCCCCTGAAATCTTTACAAGGAGGGAGTGTGTCCGTGATTCGA
GGTTGCTGATCAGAGTAGGGCGACCACTCTAAAAACGTAACTGCTTTTGAAATCACTAAGACCT
TTATAGTATTGCTGTCACTCTGGCACTTAACTGATGGGGACACACTAGAAGAATTGTGTCCTGA
GCTAGAGAAATGGCTCAGAGGTTAAGAGCACTGACTGTTCTTCCAGAGGTCCTGAGTTCAATTC
CCAGCAGCCACACAGTGTTTCACAACCATCTGTAATGGGATCCAATGACCTCTTCTGGTGTGTC
TGAAGACAGCGACTATTCATATACATAAATAAATCTTTTTAAAAAAAAAAAAAAAAAAAAAAAA
AAAAAA

hide sequence

RefSeq Acc Id:

XM_039112437 ⟹ XP_038968365

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,693 - 30,956,389 (+)	NCBI
mRatBN7.2	6	25,222,983 - 25,236,241 (+)	NCBI

RefSeq Acc Id:

XM_039112438 ⟹ XP_038968366

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,693 - 30,956,389 (+)	NCBI
mRatBN7.2	6	25,222,983 - 25,236,241 (+)	NCBI

RefSeq Acc Id:

XM_039112439 ⟹ XP_038968367

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,943,358 - 30,956,389 (+)	NCBI
mRatBN7.2	6	25,231,067 - 25,236,241 (+)	NCBI

RefSeq Acc Id:

XM_039112440 ⟹ XP_038968368

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,699 - 30,956,389 (+)	NCBI
mRatBN7.2	6	25,221,668 - 25,236,241 (+)	NCBI

RefSeq Acc Id:

XM_039112441 ⟹ XP_038968369

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,698 - 30,956,389 (+)	NCBI
mRatBN7.2	6	25,221,668 - 25,236,241 (+)	NCBI

RefSeq Acc Id:

XM_039112443 ⟹ XP_038968371

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,698 - 30,956,389 (+)	NCBI
mRatBN7.2	6	25,222,983 - 25,236,241 (+)	NCBI

RefSeq Acc Id:

XM_039112444 ⟹ XP_038968372

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,693 - 30,956,389 (+)	NCBI
mRatBN7.2	6	25,221,668 - 25,236,241 (+)	NCBI

RefSeq Acc Id:

XM_039112445 ⟹ XP_038968373

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,693 - 30,956,389 (+)	NCBI
mRatBN7.2	6	25,222,983 - 25,236,241 (+)	NCBI

RefSeq Acc Id:

XM_063262038 ⟹ XP_063118108

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,693 - 30,956,389 (+)	NCBI

RefSeq Acc Id:

XM_063262039 ⟹ XP_063118109

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,694 - 30,956,389 (+)	NCBI

RefSeq Acc Id:

XM_063262040 ⟹ XP_063118110

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,694 - 30,956,389 (+)	NCBI

RefSeq Acc Id:

XM_063262041 ⟹ XP_063118111

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,699 - 30,956,389 (+)	NCBI

RefSeq Acc Id:

XM_063262042 ⟹ XP_063118112

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,693 - 30,956,389 (+)	NCBI

RefSeq Acc Id:

XM_063262043 ⟹ XP_063118113

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	30,941,699 - 30,956,389 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001091710	(Get FASTA)	NCBI Sequence Viewer
	XP_038968365	(Get FASTA)	NCBI Sequence Viewer
	XP_038968366	(Get FASTA)	NCBI Sequence Viewer
	XP_038968367	(Get FASTA)	NCBI Sequence Viewer
	XP_038968368	(Get FASTA)	NCBI Sequence Viewer
	XP_038968369	(Get FASTA)	NCBI Sequence Viewer
	XP_038968371	(Get FASTA)	NCBI Sequence Viewer
	XP_038968372	(Get FASTA)	NCBI Sequence Viewer
	XP_038968373	(Get FASTA)	NCBI Sequence Viewer
	XP_063118108	(Get FASTA)	NCBI Sequence Viewer
	XP_063118109	(Get FASTA)	NCBI Sequence Viewer
	XP_063118110	(Get FASTA)	NCBI Sequence Viewer
	XP_063118111	(Get FASTA)	NCBI Sequence Viewer
	XP_063118112	(Get FASTA)	NCBI Sequence Viewer
	XP_063118113	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH91193	(Get FASTA)	NCBI Sequence Viewer
	EDL96173	(Get FASTA)	NCBI Sequence Viewer
	EDL96174	(Get FASTA)	NCBI Sequence Viewer
	EDL96175	(Get FASTA)	NCBI Sequence Viewer
	EDL96176	(Get FASTA)	NCBI Sequence Viewer
	EDM02928	(Get FASTA)	NCBI Sequence Viewer
	EDM02929	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000037647.5
	ENSRNOP00000079234
	ENSRNOP00000079234.1
	ENSRNOP00000091585
	ENSRNOP00000091585.1
	ENSRNOP00000092589
	ENSRNOP00000092589.1
GenBank Protein	Q5BK62	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_001091710 ⟸ NM_001098240
- UniProtKB:	Q5BK62 (UniProtKB/Swiss-Prot), A6HA73 (UniProtKB/TrEMBL), A0A8I6ADY6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MALWRAYQRALAAHPWKVQVLTAGSLMGLGDIISQQLVERRGLQQHQTGRTLTMASLGCGFVGP VVGGWYRVLDHLIPGTTKVNALKKMLLDQGGFAPCFLGCFLPLVGVLNGMSAQDNWAKLKRDYP DALITNYYLWPAVQLANFYLVPLHYRLAVVQCVAVVWNSYLSWKAHQL hide sequence

RefSeq Acc Id:

ENSRNOP00000037647 ⟸ ENSRNOT00000034207

RefSeq Acc Id:	XP_038968369 ⟸ XM_039112441
- Peptide Label:	isoform X4
- UniProtKB:	Q5BK62 (UniProtKB/Swiss-Prot), A6HA73 (UniProtKB/TrEMBL), A0A8I6ADY6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968368 ⟸ XM_039112440
- Peptide Label:	isoform X4
- UniProtKB:	Q5BK62 (UniProtKB/Swiss-Prot), A6HA73 (UniProtKB/TrEMBL), A0A8I6ADY6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968372 ⟸ XM_039112444
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6GJS1 (UniProtKB/TrEMBL), A0A8I6ADY6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968365 ⟸ XM_039112437
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038968366 ⟸ XM_039112438
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038968371 ⟸ XM_039112443
- Peptide Label:	isoform X4
- UniProtKB:	Q5BK62 (UniProtKB/Swiss-Prot), A6HA73 (UniProtKB/TrEMBL), A0A8I6ADY6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968373 ⟸ XM_039112445
- Peptide Label:	isoform X5
- UniProtKB:	A0A8I6GJS1 (UniProtKB/TrEMBL), A0A8I6ADY6 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038968367 ⟸ XM_039112439
- Peptide Label:	isoform X3
- UniProtKB:	A0A8I6ADY6 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000092589 ⟸ ENSRNOT00000102606

RefSeq Acc Id:

ENSRNOP00000091585 ⟸ ENSRNOT00000099208

RefSeq Acc Id:

ENSRNOP00000079234 ⟸ ENSRNOT00000095043

RefSeq Acc Id:	XP_063118108 ⟸ XM_063262038
- Peptide Label:	isoform X5

RefSeq Acc Id:	XP_063118112 ⟸ XM_063262042
- Peptide Label:	isoform X8

RefSeq Acc Id:	XP_063118110 ⟸ XM_063262040
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063118109 ⟸ XM_063262039
- Peptide Label:	isoform X6

RefSeq Acc Id:	XP_063118113 ⟸ XM_063262043
- Peptide Label:	isoform X9

RefSeq Acc Id:	XP_063118111 ⟸ XM_063262041
- Peptide Label:	isoform X7

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5BK62-F1-model_v2	AlphaFold	Q5BK62	1-176	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694445

Promoter ID:

EPDNEW_R4969

Type:

single initiation site

Name:

Mpv17_1

Description:

MpV17 mitochondrial inner membrane protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	26,587,428 - 26,587,488	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1310512	AgrOrtholog
BioCyc Gene	G2FUF-38347	BioCyc
Ensembl Genes	ENSRNOG00000049430	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000034207.5	UniProtKB/TrEMBL
	ENSRNOT00000095043.1	UniProtKB/TrEMBL
	ENSRNOT00000099208.1	UniProtKB/TrEMBL
	ENSRNOT00000102606.1	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7373705	IMAGE-MGC_LOAD
InterPro	Mpv17_PMP22	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:360463	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:108867	IMAGE-MGC_LOAD
NCBI Gene	360463	ENTREZGENE
PANTHER	PROTEIN MPV17	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR11266	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Mpv17_PMP22	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Mpv17	PhenoGen
RatGTEx	ENSRNOG00000049430	RatGTEx
UniProt	A0A8I5ZME0_RAT	UniProtKB/TrEMBL
	A0A8I6ADY6	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GJS1	ENTREZGENE, UniProtKB/TrEMBL
	A6HA73	ENTREZGENE, UniProtKB/TrEMBL
	F1LNG8_RAT	UniProtKB/TrEMBL
	MPV17_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2018-08-27	Mpv17	mitochondrial inner membrane protein MPV17	Mpv17	MpV17 mitochondrial inner membrane protein	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2012-08-29	Mpv17	MpV17 mitochondrial inner membrane protein	Mpv17l	MPV17 mitochondrial membrane protein-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-04-23	Mpv17l	MPV17 mitochondrial membrane protein-like	Mpv17l	Mpv17 transgene, kidney disease mutant-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-11-11	Mpv17l	Mpv17 transgene, kidney disease mutant-like	Mpv17l	MPV17 mitochondrial membrane protein-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-25	Mpv17l	MPV17 mitochondrial membrane protein-like	Mpv17l	Mpv17 transgene, kidney disease mutant-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Mpv17l	Mpv17 transgene, kidney disease mutant-like	Mpv17l_predicted	Mpv17 transgene, kidney disease mutant-like (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Mpv17l_predicted	Mpv17 transgene, kidney disease mutant-like (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - MGI

Imported Disease Annotations - OMIM