Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SLC2A12 mRNA] | CTD | PMID:31150632 | 1,1-dichloroethene | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of SLC2A12 mRNA | CTD | PMID:26682919 | 17alpha-ethynylestradiol | affects expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Ethinyl Estradiol affects the expression of SLC2A12 mRNA | CTD | PMID:26865667 | 17beta-estradiol | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of SLC2A12 mRNA | CTD | PMID:30165855 | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of SLC2A12 mRNA | CTD | PMID:29581250 | 2,2',5,5'-tetrachlorobiphenyl | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:36804509 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SLC2A12 mRNA | CTD | PMID:33956508 | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of SLC2A12 mRNA | CTD | PMID:26251327 | 4,4'-sulfonyldiphenol | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | bisphenol S results in decreased expression of SLC2A12 mRNA | CTD | PMID:34831106 | 4-hydroxyphenyl retinamide | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of SLC2A12 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of SLC2A12 mRNA | CTD | PMID:24780913 | 8-Br-cAMP | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of SLC2A12 mRNA | CTD | PMID:20147733 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of SLC2A12 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of SLC2A12 mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | Acrylamide results in decreased expression of SLC2A12 mRNA | CTD | PMID:35032568 | all-trans-retinoic acid | multiple interactions | ISO | Slc2a12 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC2A12 mRNA | CTD | PMID:36189433 | avobenzone | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | avobenzone results in increased expression of SLC2A12 mRNA | CTD | PMID:31016361 | benzo[a]pyrene | increases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of SLC2A12 mRNA | CTD | PMID:27195522 | benzo[a]pyrene | affects methylation | ISO | SLC2A12 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SLC2A12 intron | CTD | PMID:30157460 | bis(2-chloroethyl) sulfide | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Mustard Gas results in increased expression of SLC2A12 mRNA | CTD | PMID:25102026 | bisphenol A | affects expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | bisphenol A affects the expression of SLC2A12 mRNA | CTD | PMID:20170705 | bisphenol A | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SLC2A12 mRNA | CTD | PMID:34831106 | bisphenol A | decreases methylation | ISO | SLC2A12 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of SLC2A12 gene | CTD | PMID:31601247 | bisphenol A | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SLC2A12 gene | CTD | PMID:31601247 | bisphenol A | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SLC2A12 mRNA | CTD | PMID:29275510 | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SLC2A12 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SLC2A12 mRNA | CTD | PMID:26063408 | bisphenol F | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | bisphenol F results in decreased expression of SLC2A12 mRNA | CTD | PMID:34831106 | cadmium atom | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC2A12 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SLC2A12 mRNA | CTD | PMID:35301059 | camptothecin | increases methylation | ISO | SLC2A12 (Homo sapiens) | 6480464 | Camptothecin results in increased methylation of SLC2A12 gene | CTD | PMID:30720231 | cisplatin | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of SLC2A12 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of SLC2A12 mRNA | CTD | PMID:27392435 | cyclosporin A | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SLC2A12 mRNA | CTD | PMID:20106945 and PMID:27989131 | dextran sulfate | multiple interactions | ISO | Slc2a12 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC2A12 mRNA | CTD | PMID:29950665 | dioxygen | multiple interactions | ISO | Slc2a12 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SLC2A12 mRNA | CTD | PMID:30529165 | dioxygen | multiple interactions | EXP | | 6480464 | [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of SLC2A12 mRNA | CTD | PMID:33729688 | dorsomorphin | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of SLC2A12 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | EXP | | 6480464 | Endosulfan results in decreased expression of SLC2A12 mRNA | CTD | PMID:29391264 | entinostat | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | entinostat results in decreased expression of SLC2A12 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC2A12 mRNA | CTD | PMID:27188386 | entinostat | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | entinostat results in increased expression of SLC2A12 mRNA | CTD | PMID:27188386 | folic acid | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Folic Acid results in decreased expression of SLC2A12 mRNA | CTD | PMID:21867686 | fulvestrant | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of SLC2A12 gene | CTD | PMID:31601247 | genistein | affects expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Genistein affects the expression of SLC2A12 mRNA | CTD | PMID:26865667 | hydroquinone | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | hydroquinone results in decreased expression of SLC2A12 mRNA | CTD | PMID:31256213 | manganese(II) chloride | decreases expression | EXP | | 6480464 | manganese chloride results in decreased expression of SLC2A12 mRNA | CTD | PMID:28801915 | methamphetamine | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | Methamphetamine results in decreased expression of SLC2A12 mRNA | CTD | PMID:26307267 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of SLC2A12 gene | CTD | PMID:35440735 | methylmercury chloride | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of SLC2A12 mRNA | CTD | PMID:28001369 | methylmercury chloride | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of SLC2A12 mRNA | CTD | PMID:28001369 | methylphenidate | increases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | Methylphenidate results in increased expression of SLC2A12 mRNA | CTD | PMID:22470460 | mono(2-ethylhexyl) phthalate | multiple interactions | ISO | Slc2a12 (Mus musculus) | 6480464 | [mono-(2-ethylhexyl)phthalate co-treated with Tretinoin] results in increased expression of SLC2A12 mRNA | CTD | PMID:36189433 | mono(2-ethylhexyl) phthalate | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of SLC2A12 mRNA | CTD | PMID:36695872 | monosodium L-glutamate | multiple interactions | ISO | Slc2a12 (Mus musculus) | 6480464 | [Sodium Glutamate co-treated with Trans Fatty Acids] results in increased expression of SLC2A12 mRNA | CTD | PMID:19001666 | N-methyl-4-phenylpyridinium | decreases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in decreased expression of SLC2A12 mRNA | CTD | PMID:28801915 | nickel atom | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Nickel results in decreased expression of SLC2A12 mRNA | CTD | PMID:24768652 and PMID:25583101 | niclosamide | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of SLC2A12 mRNA | CTD | PMID:36318118 | paracetamol | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of SLC2A12 mRNA | CTD | PMID:26690555 and PMID:29067470 | paraquat | decreases expression | EXP | | 6480464 | Paraquat results in decreased expression of SLC2A12 mRNA | CTD | PMID:32680482 | perfluorononanoic acid | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in decreased expression of SLC2A12 mRNA | CTD | PMID:32588087 | perfluorooctanoic acid | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of SLC2A12 mRNA | CTD | PMID:37302725 | phenformin | increases expression | EXP | | 6480464 | Phenformin results in increased expression of SLC2A12 mRNA | CTD | PMID:31324951 | phenylmercury acetate | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of SLC2A12 mRNA | CTD | PMID:26272509 | phenylmercury acetate | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SLC2A12 mRNA | CTD | PMID:27188386 | potassium dichromate | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | Potassium Dichromate results in decreased expression of SLC2A12 mRNA | CTD | PMID:23608068 | rifampicin | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Rifampin results in increased expression of SLC2A12 mRNA | CTD | PMID:27199754 | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of SLC2A12 mRNA | CTD | PMID:28374803 | SB 431542 | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | sodium arsenite | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of SLC2A12 mRNA | CTD | PMID:34032870 | sunitinib | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of SLC2A12 mRNA | CTD | PMID:31533062 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of SLC2A12 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of SLC2A12 mRNA] | CTD | PMID:31150632 | thimerosal | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of SLC2A12 mRNA | CTD | PMID:27188386 | titanium dioxide | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of SLC2A12 mRNA | CTD | PMID:23557971 | titanium dioxide | multiple interactions | ISO | Slc2a12 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SLC2A12 mRNA | CTD | PMID:29950665 | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of SLC2A12 mRNA | CTD | PMID:33387578 | trichostatin A | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of SLC2A12 mRNA | CTD | PMID:24935251 | trichostatin A | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC2A12 mRNA | CTD | PMID:27188386 | trichostatin A | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of SLC2A12 mRNA | CTD | PMID:26272509 | trimellitic anhydride | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | trimellitic anhydride results in decreased expression of SLC2A12 mRNA | CTD | PMID:19042947 | troglitazone | decreases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | troglitazone results in decreased expression of SLC2A12 mRNA | CTD | PMID:28973697 | valproic acid | affects expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of SLC2A12 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SLC2A12 mRNA | CTD | PMID:19101580 more ... | vancomycin | increases expression | ISO | Slc2a12 (Mus musculus) | 6480464 | Vancomycin results in increased expression of SLC2A12 mRNA | CTD | PMID:18930951 | vorinostat | increases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | vorinostat results in increased expression of SLC2A12 mRNA | CTD | PMID:27188386 | vorinostat | multiple interactions | ISO | SLC2A12 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of SLC2A12 mRNA | CTD | PMID:27188386 | vorinostat | decreases expression | ISO | SLC2A12 (Homo sapiens) | 6480464 | vorinostat results in decreased expression of SLC2A12 mRNA | CTD | PMID:26272509 | |