Fgd2 (FYVE, RhoGEF and PH domain containing 2) - Rat Genome Database

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Gene: Fgd2 (FYVE, RhoGEF and PH domain containing 2) Rattus norvegicus
Analyze
Symbol: Fgd2
Name: FYVE, RhoGEF and PH domain containing 2
RGD ID: 1309840
Description: Predicted to enable guanyl-nucleotide exchange factor activity and phosphatidylinositol phosphate binding activity. Predicted to be involved in cytoskeleton organization and filopodium assembly. Predicted to be located in early endosome; nucleus; and ruffle. Predicted to be active in cytoplasm. Orthologous to human FGD2 (FYVE, RhoGEF and PH domain containing 2); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: FYVE, RhoGEF and PH domain-containing protein 2; LOC309653
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8207,426,407 - 7,443,207 (+)NCBIGRCr8
mRatBN7.2207,424,795 - 7,441,603 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl207,424,790 - 7,441,603 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx208,127,837 - 8,144,980 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0207,489,694 - 7,506,838 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,961,599 - 7,978,728 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0206,973,356 - 6,990,026 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,973,398 - 6,990,023 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,212,072 - 9,228,719 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,684,764 - 7,702,116 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1207,685,169 - 7,701,720 (+)NCBI
Celera208,967,909 - 8,984,674 (+)NCBICelera
Cytogenetic Map20p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cytoplasm  (IBA,ISO)
cytoskeleton  (IEA)
early endosome  (ISO)
nucleus  (ISO)
ruffle  (ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:18838382  


Genomics

Comparative Map Data
Fgd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8207,426,407 - 7,443,207 (+)NCBIGRCr8
mRatBN7.2207,424,795 - 7,441,603 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl207,424,790 - 7,441,603 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx208,127,837 - 8,144,980 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0207,489,694 - 7,506,838 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0207,961,599 - 7,978,728 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0206,973,356 - 6,990,026 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl206,973,398 - 6,990,023 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0209,212,072 - 9,228,719 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4207,684,764 - 7,702,116 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1207,685,169 - 7,701,720 (+)NCBI
Celera208,967,909 - 8,984,674 (+)NCBICelera
Cytogenetic Map20p12NCBI
FGD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38637,005,655 - 37,029,069 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl637,005,646 - 37,029,069 (+)EnsemblGRCh38hg38GRCh38
GRCh37636,973,431 - 36,996,845 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36637,081,401 - 37,104,822 (+)NCBINCBI36Build 36hg18NCBI36
Build 34637,081,400 - 37,104,822NCBI
Celera638,528,396 - 38,551,886 (+)NCBICelera
Cytogenetic Map6p21.2NCBI
HuRef636,691,770 - 36,715,184 (+)NCBIHuRef
CHM1_1636,975,223 - 36,998,669 (+)NCBICHM1_1
T2T-CHM13v2.0636,829,039 - 36,852,622 (+)NCBIT2T-CHM13v2.0
Fgd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391729,579,878 - 29,598,509 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1729,579,888 - 29,598,635 (+)EnsemblGRCm39 Ensembl
GRCm381729,360,904 - 29,379,535 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1729,360,914 - 29,379,661 (+)EnsemblGRCm38mm10GRCm38
MGSCv371729,497,859 - 29,516,480 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361729,087,926 - 29,106,565 (+)NCBIMGSCv36mm8
Celera1729,903,505 - 29,922,630 (+)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1715.26NCBI
Fgd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554376,024,301 - 6,038,349 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554376,026,087 - 6,038,740 (-)NCBIChiLan1.0ChiLan1.0
FGD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2551,473,851 - 51,497,972 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1647,343,620 - 47,374,549 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0636,566,942 - 36,591,044 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1637,762,646 - 37,787,186 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl637,762,809 - 37,785,291 (+)Ensemblpanpan1.1panPan2
FGD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1126,069,251 - 6,091,972 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl126,068,910 - 6,139,707 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha126,087,785 - 6,110,527 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0126,418,188 - 6,440,928 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl126,417,971 - 6,440,890 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1126,072,861 - 6,095,355 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0126,152,181 - 6,174,920 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0126,250,596 - 6,273,316 (+)NCBIUU_Cfam_GSD_1.0
Fgd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494641,513,954 - 41,536,375 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647622,424,042 - 22,442,689 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647622,423,851 - 22,442,795 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FGD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl732,648,222 - 32,674,529 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1732,648,260 - 32,674,539 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2737,551,703 - 37,577,990 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FGD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11735,112,453 - 35,136,161 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1735,112,815 - 35,136,017 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604436,943,781 - 36,967,321 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Fgd2
103 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:260
Count of miRNA genes:176
Interacting mature miRNAs:197
Transcripts:ENSRNOT00000041665
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354642Despr15Despair related QTL 150.0027locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)20124159021Rat
1600382Edcs3Endometrial carcinoma susceptibility QTL33.50.003uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)20125159026Rat
2317851Alcrsp22Alcohol response QTL 223.20.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
1641893Alcrsp7Alcohol response QTL 7response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)20127339237Rat
8694189Bw153Body weight QTL 1533.130.001body mass (VT:0001259)body weight gain (CMO:0000420)20129191651Rat
9590275Scort15Serum corticosterone level QTL 153.480.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20129191651Rat
7411650Foco23Food consumption QTL 2320.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20129191651Rat
9590109Sffal8Serum free fatty acids level QTL 85.320.01blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)20129191651Rat
9589155Insul32Insulin level QTL 326.380.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20129191651Rat
6893685Bw111Body weight QTL 1112.70.004body mass (VT:0001259)body weight (CMO:0000012)20132578807Rat
7411668Foco32Food consumption QTL 3280.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)20136600972Rat
9590252Scort12Serum corticosterone level QTL 1220.460.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)20136600972Rat
2305926Iddm37Insulin dependent diabetes mellitus QTL 376blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)20152784246527842Rat
1641915Colcr9Colorectal carcinoma resistance QTL 92.970.0024intestine integrity trait (VT:0010554)benign colorectal tumor number (CMO:0001795)20153065546530655Rat
1598816Memor12Memory QTL 122.4exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)20260683647606836Rat
2317057Aia27Adjuvant induced arthritis QTL 272.83joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)20289259726381954Rat
1300152Bp195Blood pressure QTL 1953.46arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2036216499243559Rat
1331772Cdexp2CD45RC expression in CD8 T cells QTL 25.7CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)20362164910078919Rat
61432Cia1Collagen induced arthritis QTL 1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)20362165614101050Rat
4889857Pur27Proteinuria QTL 2712.20.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)20460660717617956Rat
1558640Prcs2Prostate cancer susceptibility QTL 23.3prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)20460660717617956Rat
70154Insul2Insulin level QTL 23.75blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)20669170617489458Rat

Markers in Region
AI411563  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2207,441,319 - 7,441,409 (+)MAPPERmRatBN7.2
Rnor_6.0206,989,740 - 6,989,829NCBIRnor6.0
Rnor_5.0209,228,433 - 9,228,522UniSTSRnor5.0
RGSC_v3.4207,701,833 - 7,701,922UniSTSRGSC3.4
Celera208,984,391 - 8,984,480UniSTS
RH 3.4 Map2078.24UniSTS
Cytogenetic Map20p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 12 6 17 6 2 2
Low 1 43 45 35 2 35 8 11 74 35 39 9 8
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001107617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256205 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008772729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601651 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017601652 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098712 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039098715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279151 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063279153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC089841 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC168916 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000041665   ⟹   ENSRNOP00000039744
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl207,424,790 - 7,441,603 (+)Ensembl
Rnor_6.0 Ensembl206,973,398 - 6,990,023 (+)Ensembl
RefSeq Acc Id: NM_001107617   ⟹   NP_001101087
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,414 - 7,443,207 (+)NCBI
mRatBN7.2207,424,801 - 7,441,603 (+)NCBI
Rnor_6.0206,973,398 - 6,990,023 (+)NCBI
Rnor_5.0209,212,072 - 9,228,719 (+)NCBI
RGSC_v3.4207,684,764 - 7,702,116 (+)RGD
Celera208,967,909 - 8,984,674 (+)RGD
Sequence:
RefSeq Acc Id: XM_006256205   ⟹   XP_006256267
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,412 - 7,443,207 (+)NCBI
mRatBN7.2207,424,799 - 7,441,552 (+)NCBI
Rnor_6.0206,973,357 - 6,990,026 (+)NCBI
Rnor_5.0209,212,072 - 9,228,719 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017601651   ⟹   XP_017457140
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,432,190 - 7,443,207 (+)NCBI
mRatBN7.2207,430,582 - 7,441,552 (+)NCBI
Rnor_6.0206,979,232 - 6,990,026 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039098711   ⟹   XP_038954639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,411 - 7,443,207 (+)NCBI
mRatBN7.2207,424,799 - 7,441,552 (+)NCBI
RefSeq Acc Id: XM_039098712   ⟹   XP_038954640
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,411 - 7,443,207 (+)NCBI
mRatBN7.2207,424,799 - 7,441,552 (+)NCBI
RefSeq Acc Id: XM_039098713   ⟹   XP_038954641
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,410 - 7,441,773 (+)NCBI
mRatBN7.2207,424,798 - 7,440,221 (+)NCBI
RefSeq Acc Id: XM_039098714   ⟹   XP_038954642
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,408 - 7,438,077 (+)NCBI
mRatBN7.2207,424,796 - 7,436,470 (+)NCBI
RefSeq Acc Id: XM_039098715   ⟹   XP_038954643
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,407 - 7,433,486 (+)NCBI
mRatBN7.2207,424,795 - 7,431,876 (+)NCBI
RefSeq Acc Id: XM_063279150   ⟹   XP_063135220
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,411 - 7,443,207 (+)NCBI
RefSeq Acc Id: XM_063279151   ⟹   XP_063135221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,407 - 7,437,288 (+)NCBI
RefSeq Acc Id: XM_063279152   ⟹   XP_063135222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,411 - 7,437,285 (+)NCBI
RefSeq Acc Id: XM_063279153   ⟹   XP_063135223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8207,426,411 - 7,443,207 (+)NCBI
RefSeq Acc Id: NP_001101087   ⟸   NM_001107617
- UniProtKB: D3Z9I3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256267   ⟸   XM_006256205
- Peptide Label: isoform X4
- UniProtKB: D3Z9I3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457140   ⟸   XM_017601651
- Peptide Label: isoform X9
- UniProtKB: A6JJU9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000039744   ⟸   ENSRNOT00000041665
RefSeq Acc Id: XP_038954643   ⟸   XM_039098715
- Peptide Label: isoform X10
RefSeq Acc Id: XP_038954642   ⟸   XM_039098714
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038954641   ⟸   XM_039098713
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038954639   ⟸   XM_039098711
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038954640   ⟸   XM_039098712
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063135221   ⟸   XM_063279151
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063135220   ⟸   XM_063279150
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063135223   ⟸   XM_063279153
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063135222   ⟸   XM_063279152
- Peptide Label: isoform X8
Protein Domains
DH   FYVE-type   PH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3Z9I3-F1-model_v2 AlphaFold D3Z9I3 1-655 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701446
Promoter ID:EPDNEW_R11970
Type:initiation region
Name:Fgd2_1
Description:FYVE, RhoGEF and PH domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0206,973,399 - 6,973,459EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309840 AgrOrtholog
BioCyc Gene G2FUF-4376 BioCyc
Ensembl Genes ENSRNOG00000000528 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000041665.5 UniProtKB/TrEMBL
Gene3D-CATH 1.20.900.10 UniProtKB/TrEMBL
  2.30.29.30 UniProtKB/TrEMBL
  3.30.40.10 UniProtKB/TrEMBL
InterPro DBL_dom_sf UniProtKB/TrEMBL
  DH-domain UniProtKB/TrEMBL
  FGD1-4_PH2 UniProtKB/TrEMBL
  FGD2_PH1 UniProtKB/TrEMBL
  PH_type UniProtKB/TrEMBL
  Pleckstrin_homology UniProtKB/TrEMBL
  Znf_FYVE UniProtKB/TrEMBL
  Znf_FYVE-rel UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_RING/FYVE/PHD UniProtKB/TrEMBL
NCBI Gene 309653 ENTREZGENE
PANTHER FACIOGENITAL DYSPLASIA PROTEIN UniProtKB/TrEMBL
  FYVE, RHOGEF AND PH DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
Pfam FYVE UniProtKB/TrEMBL
  PF00169 UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
PhenoGen Fgd2 PhenoGen
PROSITE DH_2 UniProtKB/TrEMBL
  PH_DOMAIN UniProtKB/TrEMBL
  ZF_FYVE UniProtKB/TrEMBL
RatGTEx ENSRNOG00000000528 RatGTEx
SMART FYVE UniProtKB/TrEMBL
  RhoGEF UniProtKB/TrEMBL
  SM00233 UniProtKB/TrEMBL
Superfamily-SCOP DH-domain UniProtKB/TrEMBL
  FYVE_PHD_ZnF UniProtKB/TrEMBL
  PH domain-like UniProtKB/TrEMBL
UniProt A6JJU9 ENTREZGENE, UniProtKB/TrEMBL
  D3Z9I3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Fgd2  FYVE, RhoGEF and PH domain containing 2   Fgd2_predicted  FYVE, RhoGEF and PH domain containing 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fgd2_predicted  FYVE, RhoGEF and PH domain containing 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED