Nlrc4 (NLR family, CARD domain containing 4) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Nlrc4 (NLR family, CARD domain containing 4) Rattus norvegicus
Analyze
Symbol: Nlrc4
Name: NLR family, CARD domain containing 4
RGD ID: 1309831
Description: Predicted to enable several functions, including ATP binding activity; caspase binding activity; and protein homodimerization activity. Predicted to be involved in several processes, including positive regulation of gene expression; protein homooligomerization; and response to bacterium. Predicted to act upstream of or within regulation of apoptotic process. Predicted to be located in cytosol; intracellular membrane-bounded organelle; and plasma membrane. Predicted to be part of IPAF inflammasome complex. Human ortholog(s) of this gene implicated in familial cold autoinflammatory syndrome 4. Orthologous to human NLRC4 (NLR family CARD domain containing 4); INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Card12; caspase recruitment domain family, member 12; ice protease-activating factor; ipaf; LOC298784; NLR family CARD domain-containing protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8626,743,658 - 26,771,783 (+)NCBIGRCr8
mRatBN7.2620,991,785 - 21,018,254 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl620,995,266 - 21,018,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx621,326,076 - 21,349,081 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0621,641,928 - 21,664,923 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0621,122,373 - 21,145,374 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0622,167,874 - 22,194,755 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl622,167,919 - 22,194,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0632,058,459 - 32,081,799 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4620,934,595 - 20,953,654 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1620,933,896 - 20,956,415 (+)NCBI
Celera620,554,800 - 20,577,780 (+)NCBICelera
Cytogenetic Map6q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11374873   PMID:11390368   PMID:12646168   PMID:15030775   PMID:15107016   PMID:15190255   PMID:15882992   PMID:16648852   PMID:16648853   PMID:21874021   PMID:22484733   PMID:22885697  
PMID:26449474   PMID:26449475   PMID:26585513   PMID:32645874   PMID:34848837  


Genomics

Comparative Map Data
Nlrc4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8626,743,658 - 26,771,783 (+)NCBIGRCr8
mRatBN7.2620,991,785 - 21,018,254 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl620,995,266 - 21,018,248 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx621,326,076 - 21,349,081 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0621,641,928 - 21,664,923 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0621,122,373 - 21,145,374 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0622,167,874 - 22,194,755 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl622,167,919 - 22,194,250 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0632,058,459 - 32,081,799 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4620,934,595 - 20,953,654 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1620,933,896 - 20,956,415 (+)NCBI
Celera620,554,800 - 20,577,780 (+)NCBICelera
Cytogenetic Map6q13NCBI
NLRC4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38232,224,449 - 32,265,743 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl232,224,453 - 32,265,732 (-)EnsemblGRCh38hg38GRCh38
GRCh37232,449,518 - 32,490,812 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36232,303,022 - 32,344,305 (-)NCBINCBI36Build 36hg18NCBI36
Build 34232,361,170 - 32,402,452NCBI
Celera232,294,338 - 32,335,591 (-)NCBICelera
Cytogenetic Map2p22.3NCBI
HuRef232,188,707 - 32,229,921 (-)NCBIHuRef
CHM1_1232,379,411 - 32,420,670 (-)NCBICHM1_1
T2T-CHM13v2.0232,272,955 - 32,314,278 (-)NCBIT2T-CHM13v2.0
Nlrc4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391774,733,254 - 74,766,140 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1774,732,433 - 74,766,137 (-)EnsemblGRCm39 Ensembl
GRCm381774,426,255 - 74,459,144 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1774,425,438 - 74,459,142 (-)EnsemblGRCm38mm10GRCm38
MGSCv371774,825,635 - 74,858,448 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361774,331,277 - 74,364,090 (-)NCBIMGSCv36mm8
Celera1778,730,040 - 78,763,171 (-)NCBICelera
Cytogenetic Map17E2NCBI
cM Map1745.64NCBI
Nlrc4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955441570,880 - 603,128 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955441570,853 - 607,529 (-)NCBIChiLan1.0ChiLan1.0
NLRC4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21294,225,360 - 94,269,081 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A94,229,345 - 94,273,056 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A32,241,782 - 32,284,041 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A32,954,185 - 32,996,465 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A32,954,185 - 32,996,465 (-)Ensemblpanpan1.1panPan2
LOC102153882
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11725,517,051 - 25,518,224 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1725,304,148 - 25,312,877 (-)NCBIDog10K_Boxer_Tasha
Nlrc4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629269,606,157 - 69,649,699 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364931,206,374 - 1,237,412 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364931,189,940 - 1,233,408 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NLRC4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.13107,358,117 - 107,389,557 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23114,568,336 - 114,571,717 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NLRC4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11475,229,262 - 75,273,336 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1475,242,274 - 75,273,312 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604536,801,347 - 36,842,252 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nlrc4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473813,836,717 - 13,873,783 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473813,836,678 - 13,863,881 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nlrc4
108 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:81
Count of miRNA genes:75
Interacting mature miRNAs:77
Transcripts:ENSRNOT00000007655
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6127574569Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6127574569Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6127574569Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6127574569Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
1359023Bp272Blood pressure QTL 2722.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)61653614027261739Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
1641898Colcr4Colorectal carcinoma resistance QTL43.710.0007intestine integrity trait (VT:0010554)well differentiated malignant colorectal tumor surface area measurement (CMO:0002077)62033877762613667Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62086642281133036Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 8
Low 1 9 55 39 11 39 7 7 33 31 30 11 7
Below cutoff 28 2 2 2 1 4 39 4 11 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000007655   ⟹   ENSRNOP00000007655
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl620,995,266 - 21,018,248 (+)Ensembl
Rnor_6.0 Ensembl622,167,919 - 22,194,250 (+)Ensembl
RefSeq Acc Id: NM_001309432   ⟹   NP_001296361
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8626,747,139 - 26,770,121 (+)NCBI
mRatBN7.2620,995,266 - 21,018,248 (+)NCBI
Rnor_6.0622,171,340 - 22,194,320 (+)NCBI
Celera620,554,800 - 20,577,780 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008764491   ⟹   XP_008762713
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8626,743,658 - 26,771,783 (+)NCBI
mRatBN7.2620,991,785 - 21,018,254 (+)NCBI
Rnor_6.0622,167,874 - 22,194,755 (+)NCBI
Sequence:
RefSeq Acc Id: XM_063261611   ⟹   XP_063117681
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8626,743,658 - 26,762,375 (+)NCBI
RefSeq Acc Id: XM_063261612   ⟹   XP_063117682
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8626,743,658 - 26,762,375 (+)NCBI
RefSeq Acc Id: XR_010052054
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8626,743,658 - 26,762,375 (+)NCBI
RefSeq Acc Id: XR_592891
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8626,743,658 - 26,762,847 (+)NCBI
mRatBN7.2620,991,785 - 21,010,974 (+)NCBI
Rnor_6.0622,167,874 - 22,186,996 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_008762713   ⟸   XM_008764491
- Peptide Label: isoform X1
- UniProtKB: F1M649 (UniProtKB/Swiss-Prot),   A6H9Y2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001296361   ⟸   NM_001309432
- UniProtKB: F1M649 (UniProtKB/Swiss-Prot),   A6H9Y2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000007655   ⟸   ENSRNOT00000007655
RefSeq Acc Id: XP_063117681   ⟸   XM_063261611
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063117682   ⟸   XM_063261612
- Peptide Label: isoform X3
Protein Domains
CARD   NACHT

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M649-F1-model_v2 AlphaFold F1M649 1-1023 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694411
Promoter ID:EPDNEW_R4936
Type:single initiation site
Name:Nlrc4_1
Description:NLR family, CARD domain containing 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0622,167,896 - 22,167,956EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309831 AgrOrtholog
BioCyc Gene G2FUF-38448 BioCyc
Ensembl Genes ENSRNOG00000005810 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
  ENSRNOG00055020989 UniProtKB/Swiss-Prot
  ENSRNOG00060012557 UniProtKB/Swiss-Prot
  ENSRNOG00065020638 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000007655 ENTREZGENE
  ENSRNOT00000007655.8 UniProtKB/Swiss-Prot
  ENSRNOT00055035847 UniProtKB/Swiss-Prot
  ENSRNOT00060021271 UniProtKB/Swiss-Prot
  ENSRNOT00065034960 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.1900.50 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  1.10.533.10 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  3.80.10.10 UniProtKB/Swiss-Prot
  Death Domain, Fas UniProtKB/TrEMBL
  P-loop containing nucleotide triphosphate hydrolases UniProtKB/TrEMBL
  Ribonuclease Inhibitor UniProtKB/TrEMBL
InterPro CARD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DEATH-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LRR_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NACHT_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NLRC4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NLRC4_HD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:298784 UniProtKB/Swiss-Prot
NCBI Gene 298784 ENTREZGENE
PANTHER NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 UniProtKB/Swiss-Prot
  NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  NLR FAMILY CARD DOMAIN-CONTAINING PROTEIN 4 UniProtKB/TrEMBL
  PTHR47688 UniProtKB/Swiss-Prot
Pfam CARD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NACHT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NLRC4_HD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nlrc4 PhenoGen
PROSITE CARD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NACHT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000005810 RatGTEx
  ENSRNOG00055020989 RatGTEx
  ENSRNOG00060012557 RatGTEx
  ENSRNOG00065020638 RatGTEx
Superfamily-SCOP DEATH domain UniProtKB/TrEMBL
  P-loop containing nucleoside triphosphate hydrolases UniProtKB/TrEMBL
  RNI-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF47986 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A6H9Y2 ENTREZGENE, UniProtKB/TrEMBL
  F1M649 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-03-03 Nlrc4  NLR family, CARD domain containing 4  Card12_predicted  caspase recruitment domain family, member 12 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED