Rfc5 (replication factor C subunit 5) - Rat Genome Database

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Gene: Rfc5 (replication factor C subunit 5) Rattus norvegicus
Analyze
Symbol: Rfc5
Name: replication factor C subunit 5
RGD ID: 1309280
Description: Predicted to enable enzyme binding activity. Predicted to contribute to DNA clamp loader activity and single-stranded DNA helicase activity. Predicted to be involved in DNA repair and DNA-templated DNA replication. Predicted to be part of Ctf18 RFC-like complex and DNA replication factor C complex. Predicted to be active in nucleus. Orthologous to human RFC5 (replication factor C subunit 5); PARTICIPATES IN mismatch repair pathway; nucleotide excision repair pathway; DNA replication pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC304528; replication factor C (activator 1) 5
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81244,868,322 - 44,877,879 (+)NCBIGRCr8
mRatBN7.21239,207,484 - 39,217,041 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1239,207,484 - 39,217,312 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1240,382,784 - 40,392,340 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01240,996,594 - 41,006,150 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01240,049,569 - 40,059,125 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01244,931,494 - 44,941,051 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1244,931,494 - 44,941,324 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01246,752,012 - 46,761,569 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41240,395,942 - 40,405,498 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11240,239,703 - 40,268,387 (+)NCBI
Celera1240,850,700 - 40,860,283 (+)NCBICelera
Cytogenetic Map12q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (ISO)
17beta-estradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP,ISO)
all-trans-retinoic acid  (ISO)
AM-251  (ISO)
arsenite(3-)  (ISO)
azathioprine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
cannabidiol  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clozapine  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
flutamide  (EXP)
folic acid  (ISO)
glyphosate  (ISO)
isoprenaline  (ISO)
ivermectin  (ISO)
Lasiocarpine  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methyl methanesulfonate  (ISO)
methylseleninic acid  (ISO)
microcystin RR  (ISO)
monocrotaline  (ISO)
N-nitrosodiethylamine  (ISO)
ochratoxin A  (EXP)
oxaliplatin  (EXP)
ozone  (ISO)
paclitaxel  (ISO)
palbociclib  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctanoic acid  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
piroxicam  (ISO)
propiconazole  (ISO)
resveratrol  (ISO)
riddelliine  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
simvastatin  (ISO)
sodium arsenite  (ISO)
Soman  (EXP)
tamibarotene  (ISO)
tetrachloromethane  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
trovafloxacin  (ISO)
vincaleukoblastine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Replication clamps and clamp loaders. Hedglin M, etal., Cold Spring Harb Perspect Biol. 2013 Apr 1;5(4):a010165. doi: 10.1101/cshperspect.a010165.
4. Mechanisms and functions of DNA mismatch repair. Li GM Cell Res. 2008 Jan;18(1):85-98.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:9488738   PMID:12477932   PMID:12930902   PMID:24115439  


Genomics

Comparative Map Data
Rfc5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81244,868,322 - 44,877,879 (+)NCBIGRCr8
mRatBN7.21239,207,484 - 39,217,041 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1239,207,484 - 39,217,312 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1240,382,784 - 40,392,340 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01240,996,594 - 41,006,150 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01240,049,569 - 40,059,125 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01244,931,494 - 44,941,051 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1244,931,494 - 44,941,324 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01246,752,012 - 46,761,569 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41240,395,942 - 40,405,498 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11240,239,703 - 40,268,387 (+)NCBI
Celera1240,850,700 - 40,860,283 (+)NCBICelera
Cytogenetic Map12q16NCBI
RFC5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812118,016,703 - 118,041,448 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12118,013,588 - 118,033,130 (+)EnsemblGRCh38hg38GRCh38
GRCh3712118,454,508 - 118,470,039 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612116,938,893 - 116,954,422 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412116,917,229 - 116,932,758NCBI
Celera12118,085,448 - 118,100,501 (+)NCBICelera
Cytogenetic Map12q24.23NCBI
HuRef12115,465,092 - 115,480,369 (+)NCBIHuRef
CHM1_112118,422,177 - 118,437,716 (+)NCBICHM1_1
T2T-CHM13v2.012118,003,997 - 118,021,853 (+)NCBIT2T-CHM13v2.0
Rfc5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395117,517,210 - 117,527,088 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5117,516,168 - 117,527,112 (-)EnsemblGRCm39 Ensembl
GRCm385117,379,145 - 117,389,023 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5117,378,103 - 117,389,047 (-)EnsemblGRCm38mm10GRCm38
MGSCv375117,829,154 - 117,839,032 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365117,829,154 - 117,839,032 (-)NCBIMGSCv36mm8
Celera5114,470,100 - 114,479,973 (-)NCBICelera
Cytogenetic Map5FNCBI
cM Map556.88NCBI
Rfc5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545513,326,271 - 13,338,050 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495545513,325,912 - 13,337,241 (-)NCBIChiLan1.0ChiLan1.0
RFC5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210126,080,598 - 126,096,663 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112126,076,978 - 126,093,033 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v012115,595,398 - 115,611,442 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112118,973,645 - 118,990,308 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12118,973,560 - 118,990,308 (+)Ensemblpanpan1.1panPan2
RFC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12614,428,661 - 14,439,641 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2614,428,695 - 14,438,986 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2614,421,469 - 14,432,516 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02614,690,209 - 14,701,425 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2614,690,256 - 14,700,770 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12614,655,104 - 14,666,296 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02614,727,103 - 14,738,138 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02614,762,460 - 14,773,488 (+)NCBIUU_Cfam_GSD_1.0
Rfc5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118154,732,093 - 154,743,094 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365584,735,678 - 4,747,538 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365584,736,332 - 4,747,323 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RFC5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1434,629,951 - 34,642,585 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11434,630,374 - 34,642,598 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21436,791,707 - 36,804,213 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RFC5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.111113,352,342 - 113,368,147 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl11113,352,378 - 113,370,829 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037131,739,741 - 131,755,709 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rfc5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474715,442,328 - 15,454,550 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474715,441,338 - 15,454,577 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rfc5
55 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:54
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000001498
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
7411660Foco28Food consumption QTL 2810.90.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
9590086Insglur6Insulin/glucose ratio QTL 618.970.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)12142110980Rat
8694179Bw150Body weight QTL 1502.90.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
7411586Foco5Food consumption QTL 55.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411595Foco9Food consumption QTL 940.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12142110980Rat
7411545Bw128Body weight QTL 1285.20.001body mass (VT:0001259)body weight gain (CMO:0000420)12142110980Rat
9590147Scort7Serum corticosterone level QTL 713.610.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)12142110980Rat
2303575Insul14Insulin level QTL 144blood insulin amount (VT:0001560)blood insulin level (CMO:0000349)12142450532Rat
737979Pia22Pristane induced arthritis QTL 2253.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)12144465750Rat
634351Apr5Acute phase response QTL 56.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)12144503507Rat
2302042Pia38Pristane induced arthritis QTL 383.50.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)12144503507Rat
634350Apr4Acute phase response QTL 46orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)12117200546172005Rat
8552918Pigfal7Plasma insulin-like growth factor 1 level QTL 7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411547Bw129Body weight QTL 1290.001body mass (VT:0001259)body weight gain (CMO:0000420)6556449546669029Rat
7411597Foco10Food consumption QTL 100.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
7411641Foco19Food consumption QTL 1927.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552964Pigfal17Plasma insulin-like growth factor 1 level QTL 173.5blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449546669029Rat
7411588Foco6Food consumption QTL 60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)12556449546669029Rat
8552912Pigfal6Plasma insulin-like growth factor 1 level QTL 65blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)12556449846669029Rat
10059594Kidm46Kidney mass QTL 463.790.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)12610757946669029Rat
1302792Scl21Serum cholesterol level QTL 213.80.0011blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)12719673046669029Rat
1549829Scl48Serum cholesterol level QTL 485blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)12960327746669029Rat
2293699Bss49Bone structure and strength QTL 495.610.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)121047413746669029Rat
2300186Bmd59Bone mineral density QTL 597.10.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)121047413746669029Rat
1331761Bp218Blood pressure QTL 2182.973arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)121107382545055165Rat
61404Bw120Body weight QTL 1205.1body mass (VT:0001259)body mass index (BMI) (CMO:0000105)121235161946669029Rat
1641928Alcrsp5Alcohol response QTL 5response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)121281238546669029Rat
2303569Gluco44Glucose level QTL 442blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)121281238546669029Rat
1549902Bp269Blood pressure QTL 269arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)121318273646669029Rat
1549912Bp268Blood pressure QTL 268arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)101318273646669029Rat
2302060Pia37Pristane induced arthritis QTL 376.10.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)121319815746669029Rat
631560Apr1Acute phase response QTL 16.1orosomucoid 1 amount (VT:0010541)plasma orosomucoid 1 level (CMO:0001467)121914436246669029Rat
737822Alc10Alcohol consumption QTL 102.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)121961087040218516Rat
5684888Pia42Pristane induced arthritis QTL 42joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)121961087042828880Rat
61324Eae5Experimental allergic encephalomyelitis QTL 514nervous system integrity trait (VT:0010566)percentage of study population developing relapsing-remitting experimental autoimmune encephalomyelitis during a period of time (CMO:0001402)121961087046669029Rat
7411643Foco20Food consumption QTL 200.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)122032881946669029Rat
1556747Calcic1Intracellular calcium level QTL 13.6platelet calcium amount (VT:0010500)platelet intracellular calcium level (CMO:0000922)122806443340130419Rat
1300175Cm5Cardiac mass QTL 53.78heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)122806443345899022Rat
1600386Calcic2Intracellular calcium level QTL 20.001platelet physiology trait (VT:0005464)platelet intracellular calcium level (CMO:0000922)122806443346669029Rat
1331787Rf41Renal function QTL 412.998kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)122806455740218380Rat
1300162Bp188Blood pressure QTL 1883.19arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)123210317445899022Rat

Markers in Region
D12Rat25  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21239,215,274 - 39,215,414 (+)MAPPERmRatBN7.2
Rnor_6.01244,939,285 - 44,939,424NCBIRnor6.0
Rnor_5.01246,759,803 - 46,759,942UniSTSRnor5.0
RGSC_v3.41240,403,732 - 40,403,871UniSTSRGSC3.4
RGSC_v3.41240,403,569 - 40,403,881RGDRGSC3.4
RGSC_v3.11240,267,120 - 40,267,259RGD
Celera1240,858,499 - 40,858,656UniSTS
RH 3.4 Map12733.5RGD
RH 3.4 Map12733.5UniSTS
RH 2.0 Map12503.3RGD
FHH x ACI Map1237.59RGD
Cytogenetic Map12q16UniSTS
RH133942  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21239,216,680 - 39,216,880 (+)MAPPERmRatBN7.2
Rnor_6.01244,940,691 - 44,940,890NCBIRnor6.0
Rnor_5.01246,761,209 - 46,761,408UniSTSRnor5.0
RGSC_v3.41240,405,138 - 40,405,337UniSTSRGSC3.4
Celera1240,859,923 - 40,860,122UniSTS
RH 3.4 Map12725.2UniSTS
Cytogenetic Map12q16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 28 35 26 18 26 67 29 33 11
Low 15 22 15 1 15 8 11 7 6 8 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000001498   ⟹   ENSRNOP00000001498
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,207,503 - 39,217,312 (+)Ensembl
Rnor_6.0 Ensembl1244,931,494 - 44,941,062 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000082150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1244,935,543 - 44,936,879 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000084747   ⟹   ENSRNOP00000073675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1239,207,484 - 39,210,111 (+)Ensembl
Rnor_6.0 Ensembl1244,931,577 - 44,939,588 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000085505   ⟹   ENSRNOP00000069100
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1244,932,726 - 44,941,324 (+)Ensembl
RefSeq Acc Id: NM_001107146   ⟹   NP_001100616
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81244,868,322 - 44,877,879 (+)NCBI
mRatBN7.21239,207,484 - 39,217,041 (+)NCBI
Rnor_6.01244,931,494 - 44,941,051 (+)NCBI
Rnor_5.01246,752,012 - 46,761,569 (+)NCBI
RGSC_v3.41240,395,942 - 40,405,498 (+)RGD
Celera1240,850,700 - 40,860,283 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001100616 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI68902 (Get FASTA)   NCBI Sequence Viewer  
  EDM13825 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000001498
  ENSRNOP00000001498.5
  ENSRNOP00000073675.2
Reference Protein Sequences
RefSeq Acc Id: NP_001100616   ⟸   NM_001107146
- UniProtKB: B5DF29 (UniProtKB/TrEMBL),   F1LQL0 (UniProtKB/TrEMBL),   A0A9K3Y789 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073675   ⟸   ENSRNOT00000084747
RefSeq Acc Id: ENSRNOP00000069100   ⟸   ENSRNOT00000085505
RefSeq Acc Id: ENSRNOP00000001498   ⟸   ENSRNOT00000001498
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B5DF29-F1-model_v2 AlphaFold B5DF29 1-338 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698674
Promoter ID:EPDNEW_R9199
Type:initiation region
Name:Rfc5_1
Description:replication factor C subunit 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01244,931,568 - 44,931,628EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309280 AgrOrtholog
BioCyc Gene G2FUF-19064 BioCyc
Ensembl Genes ENSRNOG00000001134 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000001498 ENTREZGENE
  ENSRNOT00000001498.8 UniProtKB/TrEMBL
  ENSRNOT00000084747.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.8.60 UniProtKB/TrEMBL
  1.20.272.10 UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/TrEMBL
InterPro ATPase_AAA+_core UniProtKB/TrEMBL
  ATPase_AAA_core UniProtKB/TrEMBL
  DNA_pol3_clamp-load_cplx_C UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
  Rep_factor-C UniProtKB/TrEMBL
  RFC_lid UniProtKB/TrEMBL
KEGG Report rno:304528 UniProtKB/TrEMBL
NCBI Gene 304528 ENTREZGENE
PANTHER REPLICATION FACTOR C / DNA POLYMERASE III GAMMA-TAU SUBUNIT UniProtKB/TrEMBL
  REPLICATION FACTOR C SUBUNIT 5 UniProtKB/TrEMBL
Pfam AAA UniProtKB/TrEMBL
  Rad17 UniProtKB/TrEMBL
  Rep_fac_C UniProtKB/TrEMBL
PhenoGen Rfc5 PhenoGen
RatGTEx ENSRNOG00000001134 RatGTEx
SMART AAA UniProtKB/TrEMBL
Superfamily-SCOP Pol_clamp_load_C UniProtKB/TrEMBL
  SSF52540 UniProtKB/TrEMBL
UniProt A0A0G2K649_RAT UniProtKB/TrEMBL
  A0A9K3Y789 ENTREZGENE, UniProtKB/TrEMBL
  B5DF29 ENTREZGENE, UniProtKB/TrEMBL
  F1LQL0 ENTREZGENE
UniProt Secondary F1LQL0 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-16 Rfc5  replication factor C subunit 5  Rfc5  replication factor C (activator 1) 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Rfc5  replication factor C (activator 1) 5   Rfc5_predicted  replication factor C (activator 1) 5 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Rfc5_predicted  replication factor C (activator 1) 5 (predicted)      Symbol and Name status set to approved 70820 APPROVED