Fbxw11 (F-box and WD repeat domain containing 11) - Rat Genome Database

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Gene: Fbxw11 (F-box and WD repeat domain containing 11) Rattus norvegicus
Analyze
Symbol: Fbxw11
Name: F-box and WD repeat domain containing 11
RGD ID: 1309121
Description: Predicted to enable several functions, including dynein complex binding activity; microtubule plus-end binding activity; and ubiquitin ligase-substrate adaptor activity. Predicted to contribute to ubiquitin protein ligase activity. Predicted to be involved in several processes, including microtubule cytoskeleton organization; regulation of DNA-templated transcription; and transport along microtubule. Predicted to be located in centrosome; cytosol; and nucleus. Predicted to be part of SCF ubiquitin ligase complex and microtubule associated complex. Predicted to be active in several cellular components, including cytoplasmic microtubule; kinetochore; and neuronal cell body. Orthologous to human FBXW11 (F-box and WD repeat domain containing 11); PARTICIPATES IN Hedgehog signaling pathway; mTOR signaling pathway; vascular endothelial growth factor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: F-box and WD-40 domain protein 11; F-box/WD repeat-containing protein 11; LOC303024
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81017,737,181 - 17,834,834 (+)NCBIGRCr8
mRatBN7.21017,232,735 - 17,330,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,227,181 - 17,330,571 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1021,981,943 - 22,079,366 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,470,550 - 21,567,952 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01016,958,675 - 17,056,257 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01017,542,374 - 17,640,718 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,542,374 - 17,640,718 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,430,246 - 17,528,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41017,502,480 - 17,600,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11017,503,612 - 17,599,012 (+)NCBI
Celera1016,877,301 - 16,974,446 (+)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
3. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11158290   PMID:11896578   PMID:14673179   PMID:16880511   PMID:16885022   PMID:18782782   PMID:18929646   PMID:19028597   PMID:19966869   PMID:20347421   PMID:21399614  


Genomics

Comparative Map Data
Fbxw11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81017,737,181 - 17,834,834 (+)NCBIGRCr8
mRatBN7.21017,232,735 - 17,330,574 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1017,227,181 - 17,330,571 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1021,981,943 - 22,079,366 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01021,470,550 - 21,567,952 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01016,958,675 - 17,056,257 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01017,542,374 - 17,640,718 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1017,542,374 - 17,640,718 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01017,430,246 - 17,528,590 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41017,502,480 - 17,600,199 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11017,503,612 - 17,599,012 (+)NCBI
Celera1016,877,301 - 16,974,446 (+)NCBICelera
Cytogenetic Map10q12NCBI
FBXW11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385171,861,549 - 172,006,638 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5171,861,549 - 172,006,873 (-)EnsemblGRCh38hg38GRCh38
GRCh375171,288,553 - 171,433,642 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365171,221,161 - 171,366,482 (-)NCBINCBI36Build 36hg18NCBI36
Celera5167,321,013 - 167,466,463 (-)NCBICelera
Cytogenetic Map5q35.1NCBI
HuRef5166,384,918 - 166,530,978 (-)NCBIHuRef
CHM1_15170,721,014 - 170,866,350 (-)NCBICHM1_1
T2T-CHM13v2.05172,401,847 - 172,546,952 (-)NCBIT2T-CHM13v2.0
Fbxw11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391132,592,595 - 32,696,816 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1132,592,724 - 32,696,816 (+)EnsemblGRCm39 Ensembl
GRCm381132,642,555 - 32,746,816 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1132,642,724 - 32,746,816 (+)EnsemblGRCm38mm10GRCm38
MGSCv371132,542,875 - 32,646,816 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361132,542,875 - 32,646,816 (+)NCBIMGSCv36mm8
Celera1135,097,954 - 35,164,258 (+)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1119.02NCBI
Fbxw11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540824,687,493 - 24,834,345 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540824,703,477 - 24,834,522 (-)NCBIChiLan1.0ChiLan1.0
FBXW11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24166,996,014 - 167,146,079 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15165,135,553 - 165,285,624 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05167,207,643 - 167,354,730 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15174,124,499 - 174,271,971 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5174,124,499 - 174,271,977 (-)Ensemblpanpan1.1panPan2
FBXW11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1440,238,695 - 40,363,445 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl440,238,737 - 40,361,125 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha440,187,588 - 40,312,355 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0440,613,819 - 40,738,727 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl440,613,835 - 40,738,782 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1440,429,468 - 40,554,217 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0440,619,623 - 40,744,342 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0441,129,822 - 41,254,632 (+)NCBIUU_Cfam_GSD_1.0
Fbxw11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721394,508,434 - 94,619,239 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366093,256,657 - 3,341,994 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366093,256,658 - 3,341,918 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FBXW11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1652,212,607 - 52,337,913 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11652,212,401 - 52,337,893 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21656,561,220 - 56,654,277 (-)NCBISscrofa10.2Sscrofa10.2susScr3
FBXW11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12374,015,964 - 74,154,285 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2374,015,964 - 74,154,062 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660344,473,459 - 4,624,970 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fbxw11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473317,985,546 - 18,121,398 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fbxw11
400 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:219
Count of miRNA genes:169
Interacting mature miRNAs:180
Transcripts:ENSRNOT00000064079
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
737823Alc12Alcohol consumption QTL 124.5consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)101724551319388279Rat

Markers in Region
D10Rat182  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21017,245,513 - 17,245,662 (+)MAPPERmRatBN7.2
Rnor_6.01017,555,386 - 17,555,534NCBIRnor6.0
Rnor_5.01017,443,258 - 17,443,406UniSTSRnor5.0
RGSC_v3.41017,515,123 - 17,515,458RGDRGSC3.4
RGSC_v3.41017,515,215 - 17,515,363UniSTSRGSC3.4
RGSC_v3.11017,516,172 - 17,516,507RGD
Celera1016,890,021 - 16,890,169UniSTS
RH 2.0 Map10183.0RGD
SHRSP x BN Map1017.15RGD
Cytogenetic Map10q12UniSTS
RH142282  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21017,330,378 - 17,330,548 (+)MAPPERmRatBN7.2
Rnor_6.01017,640,513 - 17,640,682NCBIRnor6.0
Rnor_5.01017,528,385 - 17,528,554UniSTSRnor5.0
RGSC_v3.41017,599,994 - 17,600,163UniSTSRGSC3.4
Celera1016,974,241 - 16,974,410UniSTS
Cytogenetic Map10q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 41 57 41 19 41 8 11 74 35 35 11 8
Low 2 6
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001395595 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001395596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001414338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597238 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597241 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597242 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597243 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597244 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017597246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085889 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039085890 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063268958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473948 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000064079   ⟹   ENSRNOP00000059948
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1017,232,953 - 17,330,571 (+)Ensembl
Rnor_6.0 Ensembl1017,542,374 - 17,640,718 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000079698   ⟹   ENSRNOP00000069447
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1017,294,414 - 17,330,440 (+)Ensembl
Rnor_6.0 Ensembl1017,579,284 - 17,640,693 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000098062   ⟹   ENSRNOP00000082146
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1017,299,656 - 17,330,571 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000102539   ⟹   ENSRNOP00000079990
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1017,227,181 - 17,330,571 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118219   ⟹   ENSRNOP00000091319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1017,227,326 - 17,330,571 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000118897   ⟹   ENSRNOP00000097046
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1017,232,989 - 17,330,571 (+)Ensembl
RefSeq Acc Id: NM_001395595   ⟹   NP_001382524
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,197 - 17,834,834 (+)NCBI
mRatBN7.21017,232,926 - 17,330,574 (+)NCBI
RefSeq Acc Id: NM_001395596   ⟹   NP_001382525
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,197 - 17,834,834 (+)NCBI
mRatBN7.21017,232,926 - 17,330,574 (+)NCBI
RefSeq Acc Id: NM_001414338   ⟹   NP_001401267
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,197 - 17,834,834 (+)NCBI
mRatBN7.21017,232,926 - 17,330,574 (+)NCBI
RefSeq Acc Id: XM_017597238   ⟹   XP_017452727
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
mRatBN7.21017,232,957 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597240   ⟹   XP_017452729
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,181 - 17,834,819 (+)NCBI
mRatBN7.21017,232,735 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597241   ⟹   XP_017452730
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,181 - 17,834,819 (+)NCBI
mRatBN7.21017,232,735 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597243   ⟹   XP_017452732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
mRatBN7.21017,232,957 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017597244   ⟹   XP_017452733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
mRatBN7.21017,232,957 - 17,330,564 (+)NCBI
Rnor_6.01017,542,812 - 17,640,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039085889   ⟹   XP_038941817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,189 - 17,834,819 (+)NCBI
mRatBN7.21017,232,735 - 17,330,564 (+)NCBI
RefSeq Acc Id: XM_039085890   ⟹   XP_038941818
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
mRatBN7.21017,232,957 - 17,330,564 (+)NCBI
RefSeq Acc Id: XM_063268958   ⟹   XP_063125028
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81017,737,244 - 17,834,819 (+)NCBI
RefSeq Acc Id: XP_017452727   ⟸   XM_017597238
- Peptide Label: isoform X2
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452732   ⟸   XM_017597243
- Peptide Label: isoform X5
- UniProtKB: D3ZXC6 (UniProtKB/TrEMBL),   A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452733   ⟸   XM_017597244
- Peptide Label: isoform X6
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452729   ⟸   XM_017597240
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452730   ⟸   XM_017597241
- Peptide Label: isoform X4
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000069447   ⟸   ENSRNOT00000079698
RefSeq Acc Id: ENSRNOP00000059948   ⟸   ENSRNOT00000064079
RefSeq Acc Id: XP_038941817   ⟸   XM_039085889
- Peptide Label: isoform X1
- UniProtKB: A0A8I6GIW9 (UniProtKB/TrEMBL),   A0A0G2JVE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038941818   ⟸   XM_039085890
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZPA1 (UniProtKB/TrEMBL),   A0A8I5ZUE3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000091319   ⟸   ENSRNOT00000118219
RefSeq Acc Id: ENSRNOP00000082146   ⟸   ENSRNOT00000098062
RefSeq Acc Id: ENSRNOP00000079990   ⟸   ENSRNOT00000102539
RefSeq Acc Id: ENSRNOP00000097046   ⟸   ENSRNOT00000118897
RefSeq Acc Id: NP_001382524   ⟸   NM_001395595
- Peptide Label: isoform 1
- UniProtKB: A0A0G2JVE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001401267   ⟸   NM_001414338
- Peptide Label: isoform 3
- UniProtKB: A0A8I5ZUE3 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001382525   ⟸   NM_001395596
- Peptide Label: isoform 2
- UniProtKB: A0A8I6GMC9 (UniProtKB/TrEMBL),   A0A0G2JVE0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063125028   ⟸   XM_063268958
- Peptide Label: isoform X8
Protein Domains
F-box

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2JVE0-F1-model_v2 AlphaFold A0A0G2JVE0 1-531 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1309121 AgrOrtholog
BioCyc Gene G2FUF-25621 BioCyc
Ensembl Genes ENSRNOG00000004395 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000064079.3 UniProtKB/TrEMBL
  ENSRNOT00000079698.2 UniProtKB/TrEMBL
  ENSRNOT00000098062.1 UniProtKB/TrEMBL
  ENSRNOT00000102539.1 UniProtKB/TrEMBL
  ENSRNOT00000118219.1 UniProtKB/TrEMBL
  ENSRNOT00000118897 ENTREZGENE
  ENSRNOT00000118897.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1280.50 UniProtKB/TrEMBL
  2.130.10.10 UniProtKB/TrEMBL
  6.10.250.1840 UniProtKB/TrEMBL
InterPro Beta-TrCP_D UniProtKB/TrEMBL
  F-box_dom UniProtKB/TrEMBL
  F-box_dom_like UniProtKB/TrEMBL
  G-protein_beta_WD-40_rep UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
NCBI Gene 303024 ENTREZGENE
PANTHER F-BOX AND WD REPEAT DOMAIN-CONTAINING 11-B UniProtKB/TrEMBL
  WD40 REPEAT PF20 UniProtKB/TrEMBL
Pfam Beta-TrCP_D UniProtKB/TrEMBL
  F-box-like UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
PhenoGen Fbxw11 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE FBOX UniProtKB/TrEMBL
  WD_REPEATS_1 UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004395 RatGTEx
SMART Beta-TrCP_D UniProtKB/TrEMBL
  FBOX UniProtKB/TrEMBL
  WD40 UniProtKB/TrEMBL
Superfamily-SCOP SSF81383 UniProtKB/TrEMBL
  WD40_like UniProtKB/TrEMBL
UniProt A0A0G2JVE0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZPA1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZUE3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GIW9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GMC9 ENTREZGENE, UniProtKB/TrEMBL
  D3ZXC6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-09-25 Fbxw11  F-box and WD repeat domain containing 11  Fbxw11  F-box and WD-40 domain protein 11   Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Fbxw11  F-box and WD-40 domain protein 11   Fbxw11_predicted  F-box and WD-40 domain protein 11 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Fbxw11_predicted  F-box and WD-40 domain protein 11 (predicted)      Symbol and Name status set to approved 70820 APPROVED