Pkhd1 (PKHD1 ciliary IPT domain containing fibrocystin/polyductin) - Rat Genome Database

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Gene: Pkhd1 (PKHD1 ciliary IPT domain containing fibrocystin/polyductin) Rattus norvegicus
Analyze
Symbol: Pkhd1
Name: PKHD1 ciliary IPT domain containing fibrocystin/polyductin
RGD ID: 1308476
Description: Predicted to be involved in several processes, including establishment of centrosome localization; regulation of epithelial cell proliferation; and regulation of intracellular signal transduction. Predicted to act upstream of with a positive effect on branching morphogenesis of an epithelial tube and cell-cell junction organization. Predicted to act upstream of or within cilium assembly and kidney development. Predicted to be located in several cellular components, including apical plasma membrane; extracellular exosome; and microtubule cytoskeleton. Used to study autosomal recessive polycystic kidney disease. Biomarker of autosomal recessive polycystic kidney disease. Human ortholog(s) of this gene implicated in autosomal recessive polycystic kidney disease and polycystic kidney disease 4. Orthologous to human PKHD1 (PKHD1 ciliary IPT domain containing fibrocystin/polyductin); INTERACTS WITH bisphenol A; cefaloridine; rotenone.
Type: protein-coding
RefSeq Status: MODEL
Previously known as: AABR07067023.1; fibrocystin; LOC301287; PKHD1, fibrocystin/polyductin; polycystic kidney and hepatic disease 1; polycystic kidney and hepatic disease 1 (autosomal recessive); polycystic kidney and hepatic disease 1 homolog; polycystic kidney and hepatic disease 1 homolog (human)
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Pkhd1pck  
Genetic Models: PCK-P2rx7em8Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8930,040,466 - 30,533,834 (-)NCBIGRCr8
mRatBN7.2922,547,396 - 23,037,443 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl922,549,513 - 23,037,381 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0926,164,969 - 26,736,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl926,636,334 - 26,707,571 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0925,025,958 - 25,065,045 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0925,159,062 - 25,593,163 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4918,833,903 - 19,338,716 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1918,831,224 - 19,254,940 (-)NCBI
Celera920,127,204 - 20,618,569 (-)NCBICelera
Cytogenetic Map9q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Milder presentation of recessive polycystic kidney disease requires presence of amino acid substitution mutations. Furu L, etal., J Am Soc Nephrol. 2003 Aug;14(8):2004-14.
2. Biliary and pancreatic dysgenesis in mice harboring a mutation in Pkhd1. Gallagher AR, etal., Am J Pathol. 2008 Feb;172(2):417-29. doi: 10.2353/ajpath.2008.070381. Epub 2008 Jan 17.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Predominant extrahepatic biliary disease in autosomal recessive polycystic kidney disease: a new association. Goilav B, etal., Pediatr Transplant. 2006 May;10(3):294-8.
5. Mutation of hepatocyte nuclear factor-1beta inhibits Pkhd1 gene expression and produces renal cysts in mice. Hiesberger T, etal., J Clin Invest. 2004 Mar;113(6):814-25.
6. A Novel Pkhd1 Mutation Interacts with the Nonobese Diabetic Genetic Background To Cause Autoimmune Cholangitis. Huang W, etal., J Immunol. 2018 Jan 1;200(1):147-162. doi: 10.4049/jimmunol.1701087. Epub 2017 Nov 20.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. A mouse model for cystic biliary dysgenesis in autosomal recessive polycystic kidney disease (ARPKD). Moser M, etal., Hepatology. 2005 May;41(5):1113-21. doi: 10.1002/hep.20655.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Comprehensive gene review and curation RGD comprehensive gene curation
14. Heterozygous Pkhd1C642* mice develop cystic liver disease and proximal tubule ectasia that mimics radiographic signs of medullary sponge kidney. Shan D, etal., Am J Physiol Renal Physiol. 2019 Mar 1;316(3):F463-F472. doi: 10.1152/ajprenal.00181.2018. Epub 2019 Jan 2.
15. Cellular and subcellular localization of the ARPKD protein; fibrocystin is expressed on primary cilia. Ward CJ, etal., Hum Mol Genet. 2003 Oct 15;12(20):2703-10. Epub 2003 Aug 12.
16. The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein. Ward CJ, etal., Nat Genet 2002 Mar;30(3):259-69.
17. A mouse model of autosomal recessive polycystic kidney disease with biliary duct and proximal tubule dilatation. Woollard JR, etal., Kidney Int. 2007 Aug;72(3):328-36. doi: 10.1038/sj.ki.5002294. Epub 2007 May 23.
18. Short article: Sequence variations of PKHD1 underlie congenital hepatic fibrosis in a Chinese family. Yang N, etal., Eur J Gastroenterol Hepatol. 2019 Mar;31(3):363-367. doi: 10.1097/MEG.0000000000001295.
19. PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells. Zhang MZ, etal., Proc Natl Acad Sci U S A. 2004 Feb 24;101(8):2311-6.
Additional References at PubMed
PMID:14978161   PMID:15458427   PMID:15509540   PMID:16243292   PMID:16783394   PMID:17669261   PMID:18235088   PMID:19056867   PMID:19158352   PMID:19524688   PMID:19943112   PMID:20554582  
PMID:20709014   PMID:21300060   PMID:25367197   PMID:26136112   PMID:28154160  


Genomics

Comparative Map Data
Pkhd1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8930,040,466 - 30,533,834 (-)NCBIGRCr8
mRatBN7.2922,547,396 - 23,037,443 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl922,549,513 - 23,037,381 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0926,164,969 - 26,736,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl926,636,334 - 26,707,571 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0925,025,958 - 25,065,045 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0925,159,062 - 25,593,163 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4918,833,903 - 19,338,716 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1918,831,224 - 19,254,940 (-)NCBI
Celera920,127,204 - 20,618,569 (-)NCBICelera
Cytogenetic Map9q13NCBI
PKHD1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38651,615,299 - 52,087,615 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl651,615,299 - 52,087,613 (-)EnsemblGRCh38hg38GRCh38
GRCh37651,480,097 - 51,952,411 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36651,588,104 - 52,060,382 (-)NCBINCBI36Build 36hg18NCBI36
Celera653,139,903 - 53,613,559 (-)NCBICelera
Cytogenetic Map6p12.3-p12.2NCBI
HuRef651,314,936 - 51,783,413 (-)NCBIHuRef
CHM1_1651,482,653 - 51,954,627 (-)NCBICHM1_1
T2T-CHM13v2.0651,458,672 - 51,926,294 (-)NCBIT2T-CHM13v2.0
Pkhd1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39120,128,003 - 20,688,306 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl120,128,003 - 20,688,288 (-)EnsemblGRCm39 Ensembl
GRCm38120,057,779 - 20,618,082 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl120,057,779 - 20,618,064 (-)EnsemblGRCm38mm10GRCm38
MGSCv37120,047,860 - 20,608,138 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36120,042,930 - 20,603,208 (-)NCBIMGSCv36mm8
Celera119,948,411 - 20,498,116 (-)NCBICelera
Cytogenetic Map1A4NCBI
cM Map16.27NCBI
Pkhd1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554115,990,316 - 6,432,301 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554115,988,100 - 6,434,369 (+)NCBIChiLan1.0ChiLan1.0
PKHD1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2566,083,287 - 66,550,385 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1661,960,485 - 62,427,247 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0651,166,516 - 51,635,057 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1652,435,455 - 52,903,309 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl652,435,462 - 52,903,309 (-)Ensemblpanpan1.1panPan2
PKHD1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11219,280,866 - 19,744,669 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1219,286,822 - 19,744,141 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1219,173,042 - 19,651,204 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01219,781,225 - 20,253,821 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1219,783,877 - 20,243,554 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11219,289,289 - 19,759,402 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01219,392,649 - 19,862,367 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01219,530,405 - 20,000,289 (-)NCBIUU_Cfam_GSD_1.0
Pkhd1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494654,799,690 - 55,229,420 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364768,730,842 - 9,159,863 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364768,730,766 - 9,160,102 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PKHD1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl745,450,950 - 45,925,149 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1745,447,354 - 45,925,141 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2752,029,750 - 52,373,563 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PKHD1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11720,411,746 - 20,873,601 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366604451,528,670 - 51,991,959 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pkhd1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248554,019,056 - 4,536,324 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248554,019,088 - 4,539,289 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pkhd1
3614 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:10
Interacting mature miRNAs:11
Transcripts:ENSRNOT00000060760
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70226Eae4Experimental allergic encephalomyelitis QTL 4nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)9125661317Rat
9589055Scfw5Subcutaneous fat weight QTL 55.550.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)9137999212Rat
7411592Foco8Food consumption QTL 87.40.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9137999212Rat
9589158Gluco65Glucose level QTL 656.820.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)9137999212Rat
1300124Cm4Cardiac mass QTL 43.55heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)9140594091Rat
1298088Edpm11Estrogen-dependent pituitary mass QTL 112.5pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)9143718459Rat
1641911Alcrsp13Alcohol response QTL 13response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)9143718459Rat
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
1354650Despr5Despair related QTL 54.010.0017locomotor behavior trait (VT:0001392)amount of time spent in voluntary immobility (CMO:0001043)9125408446254084Rat
2303559Gluco54Glucose level QTL 542blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)9125408446254084Rat
61425Cia15Collagen induced arthritis QTL 154.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)9510982642921101Rat
631211Bw4Body weight QTL45.31retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)9510982650109826Rat
11353947Bp392Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)9728325252283252Rat
9589133Insul26Insulin level QTL 2617.960.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)9895256053952560Rat
7411609Foco16Food consumption QTL 1625.60.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)9895256053952560Rat
1600365Mcs20Mammary carcinoma susceptibility QTL 203mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)91353377042791750Rat
724543Cm20Cardiac mass QTL 203.9heart mass (VT:0007028)calculated heart weight (CMO:0000073)91696139840594091Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1598823Memor16Memory QTL 161.9exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)92213332249968732Rat

Markers in Region
D9Got30  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2922,911,264 - 22,911,504 (+)MAPPERmRatBN7.2
Rnor_6.0926,612,243 - 26,612,482NCBIRnor6.0
Rnor_5.0925,469,745 - 25,469,984UniSTSRnor5.0
RGSC_v3.4919,203,614 - 19,203,854RGDRGSC3.4
RGSC_v3.4919,203,615 - 19,203,854UniSTSRGSC3.4
RGSC_v3.1919,200,937 - 19,201,176RGD
Celera920,492,634 - 20,492,873UniSTS
RH 3.4 Map9212.1UniSTS
RH 3.4 Map9212.1RGD
RH 2.0 Map9174.6RGD
Cytogenetic Map9q13UniSTS
AU028005  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2922,862,453 - 22,862,619 (+)MAPPERmRatBN7.2
Rnor_6.0926,563,227 - 26,563,392NCBIRnor6.0
Rnor_5.0925,421,225 - 25,421,390UniSTSRnor5.0
RGSC_v3.4919,154,986 - 19,155,151UniSTSRGSC3.4
Celera920,444,082 - 20,444,247UniSTS
Cytogenetic Map9q13UniSTS
AU049041  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2922,626,409 - 22,626,629 (+)MAPPERmRatBN7.2
Rnor_6.0926,326,879 - 26,327,096NCBIRnor6.0
Rnor_5.0925,182,167 - 25,182,384UniSTSRnor5.0
RGSC_v3.4918,913,421 - 18,913,638UniSTSRGSC3.4
Celera920,208,062 - 20,208,263UniSTS
Cytogenetic Map9q13UniSTS


Genetic Models
This gene Pkhd1 is modified in the following models/strains:
PCK-P2rx7em8Mcwi    


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000080948   ⟹   ENSRNOP00000072399
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl922,549,513 - 23,037,381 (-)Ensembl
RefSeq Acc Id: XM_008766937   ⟹   XP_008765159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8930,040,466 - 30,533,834 (-)NCBI
mRatBN7.2922,547,396 - 23,037,443 (-)NCBI
Rnor_6.0926,164,969 - 26,736,704 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_008765159 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000072399
  ENSRNOP00000072399.2
Reference Protein Sequences
RefSeq Acc Id: XP_008765159   ⟸   XM_008766937
- UniProtKB: A0A0G2K2W1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000072399   ⟸   ENSRNOT00000080948
Protein Domains
G8   PA14

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K2W1-F1-model_v2 AlphaFold A0A0G2K2W1 1-1613 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308476 AgrOrtholog
BioCyc Gene G2FUF-28044 BioCyc
Ensembl Genes ENSRNOG00000058742 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000080948.2 UniProtKB/TrEMBL
Gene3D-CATH 2.160.20.10 UniProtKB/TrEMBL
  2.60.40.10 UniProtKB/TrEMBL
InterPro Beta_helix UniProtKB/TrEMBL
  G8_domain UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_E-set UniProtKB/TrEMBL
  IPT_dom UniProtKB/TrEMBL
  PA14/GLEYA UniProtKB/TrEMBL
  PbH1 UniProtKB/TrEMBL
  Pectin_lyas_fold UniProtKB/TrEMBL
  Pectin_lyase_fold/virulence UniProtKB/TrEMBL
NCBI Gene 301287 ENTREZGENE
PANTHER POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 UniProtKB/TrEMBL
  PTHR46769:SF1 UniProtKB/TrEMBL
Pfam Beta_helix UniProtKB/TrEMBL
  PF10162 UniProtKB/TrEMBL
  TIG UniProtKB/TrEMBL
PhenoGen Pkhd1 PhenoGen
PROSITE PA14 UniProtKB/TrEMBL
  PS51484 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000058742 RatGTEx
SMART IPT UniProtKB/TrEMBL
  PbH1 UniProtKB/TrEMBL
  SM01225 UniProtKB/TrEMBL
Superfamily-SCOP Anthrax protective antigen UniProtKB/TrEMBL
  SSF51126 UniProtKB/TrEMBL
  SSF81296 UniProtKB/TrEMBL
UniProt A0A0G2K2W1 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Pkhd1  PKHD1 ciliary IPT domain containing fibrocystin/polyductin  AABR07067023.1    Data merged from RGD:15012019 737654 PROVISIONAL
2021-09-02 AABR07067023.1    Pkhd1  PKHD1 ciliary IPT domain containing fibrocystin/polyductin  Symbol and/or name change 19259462 PROVISIONAL
2021-08-09 Pkhd1  PKHD1 ciliary IPT domain containing fibrocystin/polyductin  AABR07067023.1    Symbol and/or name change 19259462 PROVISIONAL
2019-11-08 AABR07067023.1        Symbol and Name status set to provisional 45752 PROVISIONAL
2012-06-26 Pkhd1  polycystic kidney and hepatic disease 1  Pkhd1  polycystic kidney and hepatic disease 1 homolog (human)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2011-04-29 Pkhd1  polycystic kidney and hepatic disease 1 homolog (human)  Pkhd1  polycystic kidney and hepatic disease 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-07 Pkhd1  polycystic kidney and hepatic disease 1  Pkhd1_predicted  polycystic kidney and hepatic disease 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Pkhd1_predicted  polycystic kidney and hepatic disease 1 (predicted)      Symbol and Name status set to approved 70820 APPROVED