Wwc1 (WW and C2 domain containing 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Wwc1 (WW and C2 domain containing 1) Rattus norvegicus
Analyze
Symbol: Wwc1
Name: WW and C2 domain containing 1
RGD ID: 1308329
Description: Enables protein-macromolecule adaptor activity. Involved in cell migration. Part of protein-containing complex. Orthologous to human WWC1 (WW and C2 domain containing 1); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC303039; protein KIBRA; RGD1308329; similar to KIAA0869 protein; WW, C2 and coiled-coil domain containing 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Candidate Gene For: Kidm50
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81020,804,173 - 20,958,437 (-)NCBIGRCr8
mRatBN7.21020,300,735 - 20,454,393 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1020,300,833 - 20,454,497 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01020,662,996 - 20,818,500 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1020,663,541 - 20,818,128 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01020,535,256 - 20,689,364 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41020,750,770 - 20,910,298 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11020,751,819 - 20,911,409 (-)NCBI
Celera1019,920,851 - 20,074,311 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-hydroxypropanoic acid  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
arsenous acid  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
diarsenic trioxide  (ISO)
diethylstilbestrol  (EXP,ISO)
diquat  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
doxorubicin  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (ISO)
hexestrol  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
menadione  (ISO)
mestranol  (ISO)
methapyrilene  (EXP)
methoxychlor  (EXP)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nickel sulfate  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (EXP)
urethane  (ISO)
valdecoxib  (EXP)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Temporal-spatial expression and novel biochemical properties of the memory-related protein KIBRA. Johannsen S, etal., Neuroscience. 2008 Sep 9;155(4):1165-73. doi: 10.1016/j.neuroscience.2008.06.054. Epub 2008 Jul 3.
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation. Rosse C, etal., PLoS Biol. 2009 Nov;7(11):e1000235. Epub 2009 Nov 3.
Additional References at PubMed
PMID:16684779   PMID:18190796   PMID:18596123   PMID:20159598   PMID:24117625   PMID:24141945   PMID:24682284  


Genomics

Comparative Map Data
Wwc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81020,804,173 - 20,958,437 (-)NCBIGRCr8
mRatBN7.21020,300,735 - 20,454,393 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1020,300,833 - 20,454,497 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.01020,662,996 - 20,818,500 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1020,663,541 - 20,818,128 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01020,535,256 - 20,689,364 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41020,750,770 - 20,910,298 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11020,751,819 - 20,911,409 (-)NCBI
Celera1019,920,851 - 20,074,311 (-)NCBICelera
Cytogenetic Map10q12NCBI
WWC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385168,291,645 - 168,472,303 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5168,291,645 - 168,472,303 (+)EnsemblGRCh38hg38GRCh38
GRCh375167,718,650 - 167,899,308 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365167,651,670 - 167,829,342 (+)NCBINCBI36Build 36hg18NCBI36
Celera5163,754,431 - 163,934,646 (+)NCBICelera
Cytogenetic Map5q34NCBI
HuRef5162,818,257 - 162,998,068 (+)NCBIHuRef
CHM1_15167,152,124 - 167,332,374 (+)NCBICHM1_1
T2T-CHM13v2.05168,826,515 - 169,007,094 (+)NCBIT2T-CHM13v2.0
Wwc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391135,729,226 - 35,871,354 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1135,729,227 - 35,871,354 (-)EnsemblGRCm39 Ensembl
GRCm381135,838,399 - 35,980,527 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1135,838,400 - 35,980,527 (-)EnsemblGRCm38mm10GRCm38
MGSCv371135,652,680 - 35,793,591 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361135,682,601 - 35,823,512 (-)NCBIMGSCv36mm8
Celera1139,622,284 - 39,698,629 (-)NCBICelera
Cytogenetic Map11A4NCBI
cM Map1121.96NCBI
Wwc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540821,362,644 - 21,529,157 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540821,362,644 - 21,529,164 (+)NCBIChiLan1.0ChiLan1.0
WWC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v24163,452,373 - 163,632,466 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan15161,591,925 - 161,772,011 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v05163,654,833 - 163,835,006 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.15170,420,221 - 170,602,373 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl5170,418,414 - 170,602,373 (+)Ensemblpanpan1.1panPan2
WWC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1443,279,788 - 43,431,503 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl443,280,447 - 43,431,144 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha443,232,465 - 43,387,800 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0443,697,915 - 43,852,863 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl443,701,311 - 43,853,163 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1443,467,250 - 43,622,670 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0443,661,922 - 43,817,102 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0444,168,112 - 44,323,632 (-)NCBIUU_Cfam_GSD_1.0
Wwc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440721397,318,811 - 97,464,704 (-)NCBIHiC_Itri_2
SpeTri2.0NW_004936622934,436 - 1,080,318 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WWC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1655,418,397 - 55,595,189 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11655,418,391 - 55,595,202 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
WWC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12370,515,573 - 70,684,973 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2370,515,173 - 70,684,971 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660347,997,955 - 8,171,322 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wwc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473321,542,389 - 21,712,457 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473321,541,654 - 21,712,604 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wwc1
1669 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:46
Count of miRNA genes:38
Interacting mature miRNAs:44
Transcripts:ENSRNOT00000011061
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat
631564Apr3Acute phase response QTL 33.9blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)101527595560275955Rat
6893350Bw99Body weight QTL 990.870.16body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
6893352Bw100Body weight QTL 1000.330.6body mass (VT:0001259)body weight (CMO:0000012)11590666560906665Rat
631532Cm50Cardiac mass QTL 506.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)101790711351786432Rat
1598852Anxrr19Anxiety related response QTL 195.07body movement coordination trait (VT:0005424)number of rearing movements in an experimental apparatus (CMO:0001752)101816784163167841Rat
2313055Bw96Body weight QTL 963.60.0001body mass (VT:0001259)body weight (CMO:0000012)101960648364606483Rat
2313087Bmd80Bone mineral density QTL 803.20.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)101960648364606483Rat
1554317Bmd4Bone mineral density QTL 49.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)101981604299406971Rat

Markers in Region
D10Rat216  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,301,043 - 20,301,412 (+)MAPPERmRatBN7.2
Rnor_6.01020,663,926 - 20,664,294NCBIRnor6.0
Rnor_5.01020,536,186 - 20,536,554UniSTSRnor5.0
RGSC_v3.41020,751,195 - 20,751,726RGDRGSC3.4
RGSC_v3.41020,751,336 - 20,751,704UniSTSRGSC3.4
RGSC_v3.11020,752,244 - 20,752,775RGD
Celera1019,919,648 - 19,919,975UniSTS
Celera1019,921,393 - 19,921,761UniSTS
RH 2.0 Map10226.3RGD
SHRSP x BN Map1023.85RGD
Cytogenetic Map10q12UniSTS
D10Got36  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,455,980 - 20,456,083 (+)MAPPERmRatBN7.2
Rnor_6.01020,820,086 - 20,820,188NCBIRnor6.0
Rnor_5.01020,691,249 - 20,691,351UniSTSRnor5.0
RGSC_v3.41020,912,273 - 20,912,376RGDRGSC3.4
RGSC_v3.41020,912,274 - 20,912,376UniSTSRGSC3.4
RGSC_v3.11020,913,323 - 20,913,425RGD
Celera1020,075,897 - 20,076,006UniSTS
RH 3.4 Map10215.82UniSTS
RH 3.4 Map10215.82RGD
RH 2.0 Map10227.6RGD
Cytogenetic Map10q12UniSTS
D10Mco52  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,332,116 - 20,332,380 (+)MAPPERmRatBN7.2
Rnor_6.01020,695,341 - 20,695,604NCBIRnor6.0
Rnor_5.01020,567,376 - 20,567,639UniSTSRnor5.0
RGSC_v3.41020,782,381 - 20,782,645RGDRGSC3.4
RGSC_v3.41020,782,382 - 20,782,645UniSTSRGSC3.4
RGSC_v3.11020,783,430 - 20,783,694RGD
Celera1019,952,392 - 19,952,657UniSTS
Cytogenetic Map10q12UniSTS
RH139729  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,300,136 - 20,300,325 (+)MAPPERmRatBN7.2
Rnor_6.01020,663,019 - 20,663,207NCBIRnor6.0
Rnor_5.01020,535,279 - 20,535,467UniSTSRnor5.0
RGSC_v3.41020,750,429 - 20,750,617UniSTSRGSC3.4
Celera1019,918,855 - 19,919,043UniSTS
RH 3.4 Map10240.61UniSTS
Cytogenetic Map10q12UniSTS
RH141360  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,300,477 - 20,300,701 (+)MAPPERmRatBN7.2
Rnor_6.01020,663,360 - 20,663,583NCBIRnor6.0
Rnor_5.01020,535,620 - 20,535,843UniSTSRnor5.0
RGSC_v3.41020,750,770 - 20,750,993UniSTSRGSC3.4
Celera1019,920,827 - 19,921,050UniSTS
Celera1019,919,194 - 19,919,412UniSTS
Cytogenetic Map10q12UniSTS
BI282183  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21020,300,289 - 20,300,457 (+)MAPPERmRatBN7.2
Rnor_6.01020,663,172 - 20,663,339NCBIRnor6.0
Rnor_5.01020,535,432 - 20,535,599UniSTSRnor5.0
RGSC_v3.41020,750,582 - 20,750,749UniSTSRGSC3.4
Celera1019,920,639 - 19,920,806UniSTS
Celera1019,919,008 - 19,919,175UniSTS
Cytogenetic Map10q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 18 18 18 74 35 18 11
Low 43 39 23 19 23 7 10 23 7
Below cutoff 1 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000011061   ⟹   ENSRNOP00000011061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1020,300,833 - 20,454,497 (-)Ensembl
Rnor_6.0 Ensembl1020,663,541 - 20,818,128 (-)Ensembl
RefSeq Acc Id: NM_001427362   ⟹   NP_001414291
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81020,804,173 - 20,958,437 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001414291 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CDM21937 (Get FASTA)   NCBI Sequence Viewer  
  CDM22295 (Get FASTA)   NCBI Sequence Viewer  
  EDM04097 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000011061.6
Reference Protein Sequences
RefSeq Acc Id: ENSRNOP00000011061   ⟸   ENSRNOT00000011061
RefSeq Acc Id: NP_001414291   ⟸   NM_001427362
- UniProtKB: F1M6U0 (UniProtKB/TrEMBL)
Protein Domains
C2   WW

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F1M6U0-F1-model_v2 AlphaFold F1M6U0 1-1108 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308329 AgrOrtholog
BioCyc Gene G2FUF-25536 BioCyc
Ensembl Genes ENSRNOG00000008065 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000011061.8 UniProtKB/TrEMBL
Gene3D-CATH 2.20.70.10 UniProtKB/TrEMBL
  2.60.40.150 UniProtKB/TrEMBL
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  C2_WWC UniProtKB/TrEMBL
  WW_dom_sf UniProtKB/TrEMBL
  WW_Rsp5_WWP UniProtKB/TrEMBL
KEGG Report rno:303039 UniProtKB/TrEMBL
NCBI Gene 303039 ENTREZGENE
PANTHER BOMB/KIRA PROTEINS UniProtKB/TrEMBL
  PROTEIN KIBRA UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
  PF00397 UniProtKB/TrEMBL
PhenoGen Wwc1 PhenoGen
PROSITE PS50004 UniProtKB/TrEMBL
  WW_DOMAIN_1 UniProtKB/TrEMBL
  WW_DOMAIN_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000008065 RatGTEx
SMART SM00456 UniProtKB/TrEMBL
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
  WW_Rsp5_WWP UniProtKB/TrEMBL
UniProt A6HDJ2_RAT UniProtKB/TrEMBL
  F1M6U0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-10-23 Wwc1  WW and C2 domain containing 1  Wwc1  WW, C2 and coiled-coil domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-26 Wwc1  WW, C2 and coiled-coil domain containing 1  RGD1308329_predicted  similar to KIAA0869 protein (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 RGD1308329_predicted  similar to KIAA0869 protein (predicted)  LOC303039_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC303039_predicted  similar to KIAA0869 protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL