Map1s (microtubule-associated protein 1S)

Gene: Map1s (microtubule-associated protein 1S) Rattus norvegicus

Analyze

Symbol:

Map1s

Name:

microtubule-associated protein 1S

RGD ID:

1308266

Description:

Predicted to enable DNA binding activity; cytoskeletal protein binding activity; and identical protein binding activity. Predicted to be involved in several processes, including microtubule cytoskeleton organization; neuron projection development; and regulation of microtubule depolymerization. Predicted to be located in several cellular components, including microtubule cytoskeleton; nuclear lumen; and perinuclear region of cytoplasm. Predicted to be part of microtubule associated complex. Predicted to be active in several cellular components, including dendrite; microtubule; and neuronal cell body. Orthologous to human MAP1S (microtubule associated protein 1S); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 4,4'-sulfonyldiphenol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

BPY2 interacting protein 1; Bpy2ip1; LOC290640; MAP-1S; Mtap1s

RGD Orthologs

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	MAP1S (microtubule associated protein 1S)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Map1s (microtubule-associated protein 1S)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	MAP1S (microtubule associated protein 1S)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	MAP1S (microtubule associated protein 1S)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Map1s (microtubule associated protein 1S)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	MAP1S (microtubule associated protein 1S)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	MAP1S (microtubule associated protein 1S)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Map1s (microtubule associated protein 1S)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	MAP1S (microtubule associated protein 1S)	Alliance	DIOPT (HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Map1s (microtubule-associated protein 1S)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	map1sb (microtubule-associated protein 1Sb)	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	map1sa (microtubule-associated protein 1Sa)	Alliance	DIOPT (InParanoid\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	maph-1.2	Alliance	DIOPT (InParanoid\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	maph-1.3	Alliance	DIOPT (InParanoid\|PANTHER\|PhylomeDB)
Drosophila melanogaster (fruit fly):	futsch	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PANTHER)
Xenopus tropicalis (tropical clawed frog):	map1b	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	18,551,573 - 18,561,760 (-)	NCBI		GRCr8
mRatBN7.2	16	18,516,759 - 18,527,777 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	18,517,574 - 18,527,988 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	18,559,786 - 18,569,981 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	19,692,464 - 19,702,659 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	18,612,725 - 18,622,920 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	20,268,663 - 20,278,850 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	20,267,581 - 20,278,814 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	20,126,207 - 20,136,394 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	19,017,018 - 19,027,148 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	19,017,014 - 19,027,144 (-)	NCBI
Celera	16	18,710,209 - 18,720,404 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2-methylcholine (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

acetamide (EXP)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

benzatropine (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP,ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

caffeine (ISO)

CGP 52608 (ISO)

chlorpyrifos (ISO)

choline (ISO)

cisplatin (ISO)

clofibrate (ISO)

clozapine (ISO)

coumarin (ISO)

cyclosporin A (ISO)

decabromodiphenyl ether (EXP)

endosulfan (EXP)

enzyme inhibitor (ISO)

ethanol (ISO)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

ivermectin (ISO)

L-methionine (ISO)

N-nitrosodiethylamine (ISO)

orphenadrine (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorooctanoic acid (ISO)

piperonyl butoxide (ISO)

sodium arsenite (ISO)

temozolomide (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

Triptolide (ISO)

tungsten (ISO)

urethane (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

apoptotic process (IEA)

axonogenesis (IBA,IEA)

brain development (IEA,ISO)

dendrite development (IBA,IEA)

metaphase chromosome alignment (ISO)

microtubule anchoring at centrosome (ISO)

microtubule bundle formation (ISO)

microtubule cytoskeleton organization (IBA,IEA,ISO)

mitotic spindle organization (ISO)

nervous system development (ISO)

neuron projection morphogenesis (ISO)

regulation of microtubule depolymerization (IBA,IEA)

Cellular Component

cell junction (ISO)

cell projection (ISO)

centrosome (ISO)

cytosol (IBA,IEA,ISO)

dendrite (IBA,IEA,ISO)

microtubule (IBA,IEA,ISO)

microtubule associated complex (IBA,IEA)

microtubule cytoskeleton (ISO)

microtubule organizing center (ISO)

mitotic spindle microtubule (ISO)

neuronal cell body (IBA,IEA,ISO)

nucleolus (ISO)

nucleoplasm (ISO)

nucleus (ISO)

perinuclear region of cytoplasm (ISO)

spindle (ISO)

synapse (IBA,IEA,ISO)

Molecular Function

actin binding (IBA)

actin filament binding (IEA,ISO)

beta-tubulin binding (ISO)

DNA binding (ISO)

DNA nuclease activity (ISO)

identical protein binding (IEA,ISO)

microtubule binding (IBA,IEA,ISO)

protein binding (IPI,ISO)

tubulin binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain.	Eriksson M, etal., Biochem Biophys Res Commun. 2007 Sep 14;361(1):127-32. Epub 2007 Jul 16.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:12762840	PMID:15528209	PMID:15907802	PMID:16297881	PMID:30053369

Genomics

Comparative Map Data

Map1s
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	16	18,551,573 - 18,561,760 (-)	NCBI		GRCr8
mRatBN7.2	16	18,516,759 - 18,527,777 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	16	18,517,574 - 18,527,988 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	16	18,559,786 - 18,569,981 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	16	19,692,464 - 19,702,659 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	16	18,612,725 - 18,622,920 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	16	20,268,663 - 20,278,850 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	16	20,267,581 - 20,278,814 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	16	20,126,207 - 20,136,394 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	16	19,017,018 - 19,027,148 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	16	19,017,014 - 19,027,144 (-)	NCBI
Celera	16	18,710,209 - 18,720,404 (-)	NCBI		Celera
Cytogenetic Map	16	p14	NCBI

MAP1S
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	19	17,719,480 - 17,734,513 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	19	17,719,242 - 17,734,513 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	19	17,830,289 - 17,845,322 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	19	17,691,303 - 17,706,324 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	19	17,691,302 - 17,706,324	NCBI
Celera	19	17,731,926 - 17,747,113 (+)	NCBI		Celera
Cytogenetic Map	19	p13.11	NCBI
HuRef	19	17,396,489 - 17,410,239 (+)	NCBI		HuRef
CHM1_1	19	17,829,827 - 17,844,852 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	19	17,853,600 - 17,868,633 (+)	NCBI		T2T-CHM13v2.0

Map1s
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	8	71,358,618 - 71,370,173 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	8	71,358,576 - 71,370,173 (+)	Ensembl		GRCm39 Ensembl
GRCm38	8	70,905,974 - 70,917,529 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	8	70,905,932 - 70,917,529 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	8	73,429,873 - 73,441,428 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	8	73,834,976 - 73,846,514 (+)	NCBI		MGSCv36	mm8
Celera	8	73,467,068 - 73,478,623 (+)	NCBI		Celera
Cytogenetic Map	8	B3.3	NCBI
cM Map	8	34.41	NCBI

MAP1S
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	20	22,584,448 - 22,599,684 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	19	21,591,597 - 21,606,728 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	19	17,201,883 - 17,217,116 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	19	18,165,267 - 18,192,959 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	19	18,178,445 - 18,192,873 (+)	Ensembl	panpan1.1		panPan2

MAP1S
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	20	45,147,720 - 45,162,431 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	20	45,147,751 - 45,162,408 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	20	45,059,838 - 45,074,516 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	20	45,633,065 - 45,647,732 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	20	45,633,064 - 45,647,741 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	20	44,869,181 - 44,883,893 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	20	45,279,496 - 45,294,177 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	20	45,555,242 - 45,569,965 (-)	NCBI		UU_Cfam_GSD_1.0

Map1s
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405118	203,736,892 - 203,747,728 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936596	3,286,119 - 3,296,852 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936596	3,286,031 - 3,296,855 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

MAP1S
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	59,999,168 - 60,029,865 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	60,003,116 - 60,043,133 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	59,583,390 - 59,610,014 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

MAP1S
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	6	16,192,707 - 16,208,729 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	6	16,192,734 - 16,209,553 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666074	3,188,242 - 3,204,092 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Map1s
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624908	400,577 - 408,129 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624908	400,765 - 408,154 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Map1s
35 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	46
Count of miRNA genes:	43
Interacting mature miRNAs:	45
Transcripts:	ENSRNOT00000025385
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1600369	Hcas8	Hepatocarcinoma susceptibility QTL 8			liver integrity trait (VT:0010547)	liver tumorous lesion number (CMO:0001068)	16	1	22477621	Rat
631830	Alc7	Alcohol consumption QTL 7	2.9		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	1	26727669	Rat
634355	Rends4	Renal damage susceptibility QTL 4		0.05	kidney blood vessel morphology trait (VT:0000530)	organ lesion measurement (CMO:0000677)	16	1	26727669	Rat
1582235	Insul8	Insulin level QTL 8	3.3	0.0063	blood insulin amount (VT:0001560)	calculated serum insulin level (CMO:0000359)	16	1	26727669	Rat
9590151	Scort8	Serum corticosterone level QTL 8	8.45	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	16	1	30836262	Rat
2302380	Slep6	Serum leptin concentration QTL 6	3.36		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	1	32139025	Rat
2307172	Activ4	Activity QTL 4	3.71	0.00023	locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	16	1	33418960	Rat
1354584	Despr6	Despair related QTL 6	3.1	0.0067	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	39533930	Rat
2303566	Bw90	Body weight QTL 90	2		body mass (VT:0001259)	body weight (CMO:0000012)	16	1	39533930	Rat
631561	Hcuc2	Hepatic copper content QTL 2	2.8		liver copper amount (VT:0003065)	liver total copper weight (CMO:0001507)	16	1	39533949	Rat
6903319	Bw114	Body weight QTL 114	2.7	0.0037	body mass (VT:0001259)	body weight (CMO:0000012)	16	1	43534949	Rat
7411664	Foco30	Food consumption QTL 30	11	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	16	1	44588133	Rat
1354625	Despr7	Despair related QTL 7	3.16	0.016	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	16	1	44977551	Rat
1600378	Arunc4	Aerobic running capacity QTL 4		0.03	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	16	380245	80345693	Rat
2293343	Glom16	Glomerulus QTL 16	7.4		kidney glomerulus integrity trait (VT:0010546)	kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)	16	832236	46053497	Rat
2312660	Bw95	Body weight QTL 95		0.05	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	16	832236	59492508	Rat
2312663	Slep9	Serum leptin concentration QTL 9		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	16	832236	59492508	Rat
2312666	Insul16	Insulin level QTL 16		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	16	832236	59492508	Rat
2312669	Stl23	Serum triglyceride level QTL 23		0.01	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	16	832236	59492508	Rat
1300133	Rf24	Renal function QTL 24	3.64		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	16	3380150	21361552	Rat
2306902	Bp339	Blood pressure QTL 339		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	3380150	43025077	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	16	4227609	43025077	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	4227609	43025077	Rat
70183	BpQTLcluster13	Blood pressure QTL cluster 13	3.654		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	16	4227609	43025077	Rat
737819	Hcas4	Hepatocarcinoma susceptibility QTL 4	4.43		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	16	4227609	46975965	Rat
61405	Niddm6	Non-insulin dependent diabetes mellitus QTL 6	3.66	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	16	4227609	48972724	Rat
61338	Bp23	Blood pressure QTL 23	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	16	4227609	49227609	Rat
737826	Alc11	Alcohol consumption QTL 11	3.2		consumption behavior trait (VT:0002069)	ethanol drink intake rate (CMO:0001407)	16	4227609	60252231	Rat
631517	Scl9	Serum cholesterol level QTL 9	3.3		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	16	15726433	21034895	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor depth of invasion (CMO:0001888)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat
70205	Gcr3	Gastric cancer resistance QTL 3	2.3		stomach morphology trait (VT:0000470)	stomach tumor diameter (CMO:0001889)	16	17696791	82635055	Rat

Markers in Region

RH133725

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	16	18,517,731 - 18,517,937 (+)	MAPPER	mRatBN7.2
Rnor_6.0	16	20,268,821 - 20,269,026	NCBI	Rnor6.0
Rnor_5.0	16	20,126,365 - 20,126,570	UniSTS	Rnor5.0
RGSC_v3.4	16	19,017,176 - 19,017,381	UniSTS	RGSC3.4
Celera	16	18,710,367 - 18,710,572	UniSTS
RH 3.4 Map	16	182.8	UniSTS
Cytogenetic Map	16	p14	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	1	22	15	12	7	12			68	18	35	2
Low	2	21	42	29	12	29	8	11	6	17	6	9	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001106070	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC169058	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH474031	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ211658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000016	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000025385 ⟹ ENSRNOP00000025385

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	16	18,517,574 - 18,527,988 (-)	Ensembl
Rnor_6.0 Ensembl	16	20,267,581 - 20,278,814 (-)	Ensembl

RefSeq Acc Id:

NM_001106070 ⟹ NP_001099540

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	16	18,551,573 - 18,561,760 (-)	NCBI
mRatBN7.2	16	18,517,574 - 18,527,762 (-)	NCBI
Rnor_6.0	16	20,268,663 - 20,278,850 (-)	NCBI
Rnor_5.0	16	20,126,207 - 20,136,394 (-)	NCBI
RGSC_v3.4	16	19,017,018 - 19,027,148 (-)	RGD
Celera	16	18,710,209 - 18,720,404 (-)	RGD

Sequence:

show sequence

GGCCCGGCGTTCAGAGCGTCCGGGCGGTGCGAAGATGGCGGCGGTGATGGCGGCGCCGGAGCCT
GCGGAGGCGCCCAGCTCCCTGCTGTTGCTGGTGGTGGGCGGCGAGTGCGGTTGCCCCGGGCTGC
TGGCCTACGTCCTGGAGGAGTTGGAACGAGGTGTTCGCTCGTGGGAGGATGTAGACCCCGATGT
TTGCAGCCTGGATGAGCAGCTCAAGGCCTTTGTGTCCCGGCATTCCGCCACCTTCTCCAGCATA
GTGAAAGGGCAGCGGAGCCTGCACCACCGTGGAGAGACCCTGGAGACACTGGTCCTGCTGAATC
CCTCAGACAAGTCCCTGTGTGATGAGCTCCGGAACCTCCTGATGGACCCCGCCCCTCACAAACT
GCTGGTCCTGGCAGGGCCCTGCCTGGAGGAGACTGGGGAGCTACTGCTGCAGACTGGGGGGTTC
TCGGCCCACCACTTCCTGCAGGTGCTGGGGGACAAAGAGGTTCAGGATGCACTGGCCTCGGCAC
CAGCAGCCCCGGCCCTCACAGTGTCCTGTCCAACCTTTGGGGACTGGGCGCTGCTGGGACCTGC
ACCTGGGCTGCGGTTGCGACTAAACCCGCCTGCACGGCTGCCATCCTCAGAGGGCCTCCGTGCC
TTCCTGGAGTATGTGGCTGAGTCGCTGGAGCCACCATCGCCCTTCGAGTTGTTGGAACCCCCGG
CTACAGGTGGCTTTCTGCGCCTGGCACGACCCTGTTGCTATGTGTTCCCGGGTGGCCTGGGAGA
CGCTGCCTTCTTCGCTGTCAACGGCTTTACAGTGCTGGTGAACGGCGGCTCCAACCCCAAGTCG
AGCTTCTGGAAGCTGGTGCGCCACCTGGATCGCGTGGACGCCGTGCTTGTGACCCACGCGGGTG
CTGACAGCCTGCCTGGCCTCAACAGCCTGCTGCGCCGCAAACTGGCAGAGCGAGAGGCAGCCGC
AGGACCGCAGGGACAGCATGAGGAGCGGCTGCGTAGGCTGCTGTCACCTGCACTGGGCGTGGTG
TTCCTGAATGCTCGTGAGGCTGGGTCGCGGTTACGTGGGGGCGAGGACGAGGCAGTGTGTGCGC
GGAGCCTGCTACGCAGCCTGGGCATCGTCCCTCTGCCGCTGCAGCGCGGCCCACAGCCCTCGTG
CCCCACAGTCCTTTTCGAGAAGCTAGGCGTAGGCCGCCTTGAGCTCTTTGTGCTGCATCCTCCT
CCTGGGGACCCTGCAGCACCTGCCTGTGCTCTGCTCGTGTGGCAGCCAGCAGCGCCTGGTGACA
AGGTGGTCCGAGTGCTGTTTCCTGGCCGCACACCACCAGCGCGCCTGCTGGATGGGCTACAGCG
CCTGCAGCACCTGCCGTGCCTACGTAGGCCAGTAGTCACCACGCAAGACCTGGAAGTGCCCTCA
AGGGCCAACAGCCAAGACAGTCTGGCCTCGAGGGACAGTACACGCAAGGAGCCAGTCCGTGGCA
CTGTTGGTGCCACCAGCAGGAGTGCAGTGCGAAGGGAACCTGCCCTGGCCACTCGTGACCAGAA
GAAGGACACAAAACCTGGGCCCACTCGGTCTACAGTCCGAGACGTGCGCCGCTCCGGGCCTGGT
GTTGTCACCACAAAGCCTCGAGTGTCACAGAATGGGCCTCGTGCCCCAGTTCCAGCAGCGCCAC
CTGCAGCCCCTGCGCCCGAGTTCCCTGGAGAAGCAGAGAACATCGTGGAGTCGGAGCGGCCACC
TGCCCCATCCCCGACCTTGTCCCCAGCTCAGTCCCCACCACCTACAGCACCCGGCAATAGCCCT
GAGCGCCTATCACTCAGCCCGCTGCGCCCAGAACCTGCCCCAGACGCATCCCCGTCAGCCACAA
CGCCCACGCTGACCACACCCTCTCTTCCCGCGGAGCTGGGCTCACCCCACTCAACTGAGGTGGA
CGAGTCGCTCTCCGTGTCCTTCGAGCAAGTACTGCCAGCAGGTGATGCAGGGCTTAGCCTGCCC
CTGCGCCTCGCACGCCGCTCCACATCTCCTCATGATGTAGACCTGTGCCTTGTGTCACCCTGTG
AGTTTTCACACCGCAAGCCACCCCCTCCTGCATCCCCAGGCAGCTCAGACAGCAGTGCTCGGTC
ACAGGAGCGGCCACCCGAGACTCCACCCACGTCTGTGAGCGAGTCACTGCCCACATTGTCTGAC
TCTGATCCCGTGCCTGTGGCGGATTCTGATGACGATGCAGGCAGTGAGAGCGCGGCCAGGGACC
CGCTGCCTACACCTCGTGTGCCACCACCACTGCCGGACGCACCAGGAATCTGCATGGTGGACCC
TGAGGCGCTACCACCTCGTGCACGGCAGCCTCTCAGCACAGCCAATTCCAGCCGTGGCCGCAAG
GCCCCTGCAAGGCCAAGCTCTGCGTCTGCAGCCCCCAGAGCTGCAACTGTAGCTGCCAAGACAA
AGGGTCCAGTGGGGGACCGGAGCCGGCCACTCAGTGCCCGCAGCGAGCCTGCAGACAAACCAGG
CCGAGTGCCCCTCACCAGGAAGCCCTCGGTCCCTAAGACAGTCCCCAAGATGGCCTCTGCCACA
AGGAACTCCTCTGGACCCAGTAGCCGCCCTGCACCGCTTGCTGCTGGCTCCCCTGTGTACCTGG
ACCTGGCCTACCTGCCTGGTGGCGGTGCTGGCCACCTGGACCAGAACTTCTTCCTGCGTGTGCG
TGCACTCTGCTATGTCATCAGTGGGCAAGGCCAGCGCCAGGAAGAGGGCCTGCGTGGCGTGCTG
GATGCATTGCTGGCTGGCAAGAGGCAGTGGGACCTTGACCTGCAGGTCACACTGATCCCCACCT
TCGACTCTGCAGTGATGCACAGGTGGTATGAGGAGACGCATGAGCAGCACCAGGCACTGGGCAT
CAGGGTGCTGGGCAGCGGCAGCCTGGTGTCCATGCAGGACGAGGCCTTCCCTGCCTGCAAGGTG
GAGTTCTAGCCCCACACTGCAGGGCGGCCCGGGAGCAACAGTTCTGTGTGTGACGCACCCAGGG
CGAGAGCCACACCGCTTTATCTCTTGTCCGCGCCCCATCACATGCCAAGCACGGCTCTCCATGC
CTTCTGTCCTAGAACTCAGGTTGGAGAGGCAGAAGGATCTATGCGGAGTCCAGGCTAGCCTGGG
CTACATAGTGAATCCTTGTTTCAAAACCACAAAAAATAAACCAGATGGCTGAG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001099540	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI69058	(Get FASTA)	NCBI Sequence Viewer
	EDL90755	(Get FASTA)	NCBI Sequence Viewer
	EDL90756	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000025385
	ENSRNOP00000025385.7
GenBank Protein	P0C5W1	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001099540 ⟸ NM_001106070

- UniProtKB:

P0C5W1 (UniProtKB/Swiss-Prot), B5DFH2 (UniProtKB/TrEMBL), A0A0H2UHQ3 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAAVMAAPEPAEAPSSLLLLVVGGECGCPGLLAYVLEELERGVRSWEDVDPDVCSLDEQLKAFV
SRHSATFSSIVKGQRSLHHRGETLETLVLLNPSDKSLCDELRNLLMDPAPHKLLVLAGPCLEET
GELLLQTGGFSAHHFLQVLGDKEVQDALASAPAAPALTVSCPTFGDWALLGPAPGLRLRLNPPA
RLPSSEGLRAFLEYVAESLEPPSPFELLEPPATGGFLRLARPCCYVFPGGLGDAAFFAVNGFTV
LVNGGSNPKSSFWKLVRHLDRVDAVLVTHAGADSLPGLNSLLRRKLAEREAAAGPQGQHEERLR
RLLSPALGVVFLNAREAGSRLRGGEDEAVCARSLLRSLGIVPLPLQRGPQPSCPTVLFEKLGVG
RLELFVLHPPPGDPAAPACALLVWQPAAPGDKVVRVLFPGRTPPARLLDGLQRLQHLPCLRRPV
VTTQDLEVPSRANSQDSLASRDSTRKEPVRGTVGATSRSAVRREPALATRDQKKDTKPGPTRST
VRDVRRSGPGVVTTKPRVSQNGPRAPVPAAPPAAPAPEFPGEAENIVESERPPAPSPTLSPAQS
PPPTAPGNSPERLSLSPLRPEPAPDASPSATTPTLTTPSLPAELGSPHSTEVDESLSVSFEQVL
PAGDAGLSLPLRLARRSTSPHDVDLCLVSPCEFSHRKPPPPASPGSSDSSARSQERPPETPPTS
VSESLPTLSDSDPVPVADSDDDAGSESAARDPLPTPRVPPPLPDAPGICMVDPEALPPRARQPL
STANSSRGRKAPARPSSASAAPRAATVAAKTKGPVGDRSRPLSARSEPADKPGRVPLTRKPSVP
KTVPKMASATRNSSGPSSRPAPLAAGSPVYLDLAYLPGGGAGHLDQNFFLRVRALCYVISGQGQ
RQEEGLRGVLDALLAGKRQWDLDLQVTLIPTFDSAVMHRWYEETHEQHQALGIRVLGSGSLVSM
QDEAFPACKVEF

hide sequence

RefSeq Acc Id:

ENSRNOP00000025385 ⟸ ENSRNOT00000025385

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P0C5W1-F1-model_v2	AlphaFold	P0C5W1	1-972	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13700010

Promoter ID:

EPDNEW_R10533

Type:

single initiation site

Name:

Map1s_1

Description:

microtubule-associated protein 1S

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	16	20,278,838 - 20,278,898	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308266	AgrOrtholog
BioCyc Gene	G2FUF-11818	BioCyc
Ensembl Genes	ENSRNOG00000018781	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000025385	ENTREZGENE
	ENSRNOT00000025385.7	UniProtKB/TrEMBL
InterPro	MAP1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RibonucZ/Hydroxyglut_hydro	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:290640	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene	290640	ENTREZGENE
PANTHER	PTHR13843	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR13843:SF11	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Map1s	PhenoGen
RatGTEx	ENSRNOG00000018781	RatGTEx
Superfamily-SCOP	SSF56281	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0H2UHQ3	ENTREZGENE, UniProtKB/TrEMBL
	B5DFH2	ENTREZGENE, UniProtKB/TrEMBL
	MAP1S_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-08-29	Map1s	microtubule-associated protein 1S	Mtap1s	microtubule-associated protein 1S	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-03-03	Mtap1s	microtubule-associated protein 1S	Bpy2ip1_predicted	BPY2 interacting protein 1 (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-01-12	Bpy2ip1_predicted	BPY2 interacting protein 1 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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