Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | increases expression | ISO | Arl6ip4 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of ARL6IP4 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of ARL6IP4 mRNA | CTD | PMID:26496021 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arl6ip4 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARL6IP4 mRNA | CTD | PMID:21570461 | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of ARL6IP4 mRNA | CTD | PMID:21346803 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ARL6IP4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ARL6IP4 mRNA | CTD | PMID:28628672 | acrolein | multiple interactions | ISO | ARL6IP4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of ARL6IP4 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of ARL6IP4 mRNA | CTD | PMID:32699268 | alpha-pinene | multiple interactions | ISO | ARL6IP4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of ARL6IP4 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of ARL6IP4 mRNA | CTD | PMID:32699268 | atrazine | increases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Atrazine results in increased expression of ARL6IP4 mRNA | CTD | PMID:22378314 | benzo[a]pyrene | increases methylation | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ARL6IP4 promoter | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | increases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of ARL6IP4 mRNA | CTD | PMID:26496021 | bisphenol A | decreases methylation | ISO | Arl6ip4 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of ARL6IP4 promoter | CTD | PMID:27312807 | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ARL6IP4 gene | CTD | PMID:28505145 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ARL6IP4 mRNA | CTD | PMID:25181051 and PMID:34947998 | bisphenol F | multiple interactions | ISO | ARL6IP4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ARL6IP4 mRNA | CTD | PMID:28628672 | caffeine | affects phosphorylation | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of ARL6IP4 protein | CTD | PMID:35688186 | casticin | decreases expression | ISO | Arl6ip4 (Mus musculus) | 6480464 | casticin results in decreased expression of ARL6IP4 mRNA | CTD | PMID:28444820 | choline | multiple interactions | ISO | Arl6ip4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARL6IP4 gene | CTD | PMID:20938992 | clofibrate | decreases expression | ISO | Arl6ip4 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of ARL6IP4 mRNA | CTD | PMID:23811191 | cobalt dichloride | decreases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of ARL6IP4 mRNA | CTD | PMID:19320972 | copper(II) sulfate | decreases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of ARL6IP4 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ARL6IP4 mRNA | CTD | PMID:25562108 | dexamethasone | multiple interactions | ISO | ARL6IP4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ARL6IP4 mRNA | CTD | PMID:28628672 | dibutyl phthalate | decreases expression | ISO | Arl6ip4 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of ARL6IP4 mRNA | CTD | PMID:17361019 | disodium selenite | increases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of ARL6IP4 mRNA | CTD | PMID:18175754 | elemental selenium | increases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Selenium results in increased expression of ARL6IP4 mRNA | CTD | PMID:19244175 | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of ARL6IP4 mRNA | CTD | PMID:29391264 | enzyme inhibitor | multiple interactions | ISO | ARL6IP4 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of ARL6IP4 protein | CTD | PMID:23301498 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of ARL6IP4 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Arl6ip4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARL6IP4 gene | CTD | PMID:20938992 | folic acid | increases expression | ISO | Arl6ip4 (Mus musculus) | 6480464 | Folic Acid results in increased expression of ARL6IP4 mRNA | CTD | PMID:25629700 | FR900359 | affects phosphorylation | ISO | ARL6IP4 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ARL6IP4 protein | CTD | PMID:37730182 | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of ARL6IP4 mRNA | CTD | PMID:24136188 | hexadecanoic acid | decreases phosphorylation | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Palmitic Acid results in decreased phosphorylation of ARL6IP4 protein | CTD | PMID:28073184 | indometacin | multiple interactions | ISO | ARL6IP4 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of ARL6IP4 mRNA | CTD | PMID:28628672 | ivermectin | decreases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ARL6IP4 protein | CTD | PMID:32959892 | L-methionine | multiple interactions | ISO | Arl6ip4 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of ARL6IP4 gene | CTD | PMID:20938992 | Licochalcone B | increases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | licochalcone B results in increased expression of ARL6IP4 mRNA | CTD | PMID:33647349 | methotrexate | affects response to substance | ISO | ARL6IP4 (Homo sapiens) | 6480464 | ARL6IP4 protein affects the susceptibility to Methotrexate | CTD | PMID:16217747 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of ARL6IP4 mRNA | CTD | PMID:24136188 | ozone | multiple interactions | ISO | ARL6IP4 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of ARL6IP4 mRNA more ... | CTD | PMID:32699268 and PMID:35430440 | paracetamol | decreases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ARL6IP4 mRNA | CTD | PMID:22230336 | selenium atom | increases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Selenium results in increased expression of ARL6IP4 mRNA | CTD | PMID:19244175 | senecionine | decreases expression | ISO | Arl6ip4 (Mus musculus) | 6480464 | senecionine results in decreased expression of ARL6IP4 protein | CTD | PMID:35357534 | sodium arsenite | increases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of ARL6IP4 mRNA | CTD | PMID:34032870 | valproic acid | increases methylation | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of ARL6IP4 gene | CTD | PMID:29154799 | vitamin E | increases expression | ISO | ARL6IP4 (Homo sapiens) | 6480464 | Vitamin E results in increased expression of ARL6IP4 mRNA | CTD | PMID:19244175 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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