Predicted to enable protein homodimerization activity; ubiquitin ligase-substrate adaptor activity; and ubiquitin protein ligase activity. Predicted to be involved in several processes, including SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; positive regulation of nitrogen compound metabolic process; and telomere maintenance. Predicted to act upstream of or within several processes, including common myeloid progenitor cell proliferation; protein destabilization; and regulation of DNA damage checkpoint. Predicted to be located in cytoplasm. Predicted to be part of SCF ubiquitin ligase complex. Orthologous to human FBXO4 (F-box protein 4); PARTICIPATES IN ubiquitin/proteasome degradation pathway; INTERACTS WITH 2,3,7,8-Tetrachlorodibenzofuran; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXO4 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXO4 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXO4 mRNA
[INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of FBXO4 mRNA
[pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of FBXO4 mRNA and PPARA protein affects the reaction [pirinixic acid results in increased expression of FBXO4 mRNA]