Predicted to enable catalase activity. Predicted to be involved in cellular oxidant detoxification and response to oxidative stress. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Barrett's adenocarcinoma and Barrett's esophagus. Orthologous to human GPX7 (glutathione peroxidase 7); PARTICIPATES IN arachidonic acid metabolic pathway; glutathione metabolic pathway; INTERACTS WITH 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of GPX7 mRNA
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of GPX7 mRNA
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased methylation of GPX7 promoter and [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of GPX7 mRNA
[Diethylnitrosamine co-treated with Phenobarbital] results in decreased methylation of GPX7 promoter and [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of GPX7 mRNA
[Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of GPX7 mRNA and NR1I3 protein affects the reaction [Phenobarbital results in increased expression of GPX7 mRNA]
[NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPX7 mRNA
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of GPX7 mRNA
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in decreased expression of GPX7 mRNA
[NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GPX7 mRNA
DNA hypermethylation regulates the expression of members of the Mu-class glutathione S-transferases and glutathione peroxidases in Barrett's adenocarcinoma.