Tmem237 (transmembrane protein 237) - Rat Genome Database

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Gene: Tmem237 (transmembrane protein 237) Rattus norvegicus
Analyze
Symbol: Tmem237
Name: transmembrane protein 237
RGD ID: 1306705
Description: Predicted to be involved in cilium assembly and regulation of Wnt signaling pathway. Predicted to be located in cone photoreceptor outer segment; photoreceptor connecting cilium; and rod photoreceptor outer segment. Predicted to be active in ciliary transition zone. Human ortholog(s) of this gene implicated in Joubert syndrome and Joubert syndrome 14. Orthologous to human TMEM237 (transmembrane protein 237); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Als2cr4; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4; LOC316412
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,027,481 - 68,066,731 (-)NCBIGRCr8
mRatBN7.2960,533,348 - 60,569,253 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl960,535,233 - 60,572,567 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,031,671 - 69,063,867 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0974,147,630 - 74,179,830 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0972,465,914 - 72,498,107 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0965,882,063 - 65,917,424 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl965,882,054 - 65,917,132 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0965,688,765 - 65,725,024 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4957,663,702 - 57,696,158 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1957,804,978 - 57,843,466 (-)NCBI
Celera957,975,459 - 58,006,983 (-)NCBICelera
Cytogenetic Map9q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. TMEM237 is mutated in individuals with a Joubert syndrome related disorder and expands the role of the TMEM family at the ciliary transition zone. Huang L, etal., Am J Hum Genet. 2011 Dec 9;89(6):713-30. doi: 10.1016/j.ajhg.2011.11.005.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:19946888   PMID:20375344  


Genomics

Comparative Map Data
Tmem237
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,027,481 - 68,066,731 (-)NCBIGRCr8
mRatBN7.2960,533,348 - 60,569,253 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl960,535,233 - 60,572,567 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,031,671 - 69,063,867 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0974,147,630 - 74,179,830 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0972,465,914 - 72,498,107 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0965,882,063 - 65,917,424 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl965,882,054 - 65,917,132 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0965,688,765 - 65,725,024 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4957,663,702 - 57,696,158 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1957,804,978 - 57,843,466 (-)NCBI
Celera957,975,459 - 58,006,983 (-)NCBICelera
Cytogenetic Map9q31NCBI
TMEM237
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382201,620,186 - 201,643,503 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2201,620,184 - 201,643,570 (-)EnsemblGRCh38hg38GRCh38
GRCh372202,484,909 - 202,508,226 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362202,193,152 - 202,216,469 (-)NCBINCBI36Build 36hg18NCBI36
Build 342202,313,928 - 202,333,173NCBI
Celera2196,236,809 - 196,260,126 (-)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2194,333,023 - 194,356,370 (-)NCBIHuRef
CHM1_12202,491,420 - 202,514,771 (-)NCBICHM1_1
T2T-CHM13v2.02202,100,839 - 202,124,155 (-)NCBIT2T-CHM13v2.0
Tmem237
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39159,139,743 - 59,159,567 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl159,139,749 - 59,159,567 (-)EnsemblGRCm39 Ensembl
GRCm38159,100,584 - 59,120,422 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,100,590 - 59,120,408 (-)EnsemblGRCm38mm10GRCm38
MGSCv37159,157,437 - 59,176,940 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36159,045,139 - 59,064,642 (-)NCBIMGSCv36mm8
Celera159,616,880 - 59,636,334 (-)NCBICelera
Cytogenetic Map1C1.3NCBI
cM Map129.2NCBI
Tmem237
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955403148,183 - 172,386 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955403148,181 - 173,350 (+)NCBIChiLan1.0ChiLan1.0
TMEM237
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213104,242,783 - 104,266,015 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B104,257,783 - 104,281,108 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B88,873,362 - 88,896,689 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B207,028,061 - 207,051,388 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B207,028,061 - 207,051,206 (-)Ensemblpanpan1.1panPan2
TMEM237
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13710,691,010 - 10,709,632 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3710,691,743 - 10,709,606 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3711,574,959 - 11,593,576 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03710,596,157 - 10,614,774 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3710,596,158 - 10,614,800 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13710,577,092 - 10,595,709 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03710,555,642 - 10,574,273 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03710,549,365 - 10,567,982 (-)NCBIUU_Cfam_GSD_1.0
Tmem237
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303158,902,214 - 158,921,881 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936726869,238 - 891,283 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936726872,368 - 892,185 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM237
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15105,252,479 - 105,276,970 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115105,255,485 - 105,276,624 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
TMEM237
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11087,307,141 - 87,326,618 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1087,307,903 - 87,327,299 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040112,083,373 - 112,106,810 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem237
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624899206,878 - 238,737 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624899209,810 - 239,404 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmem237
201 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:389
Count of miRNA genes:219
Interacting mature miRNAs:253
Transcripts:ENSRNOT00000031866
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)92375402461381613Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)94996854671098346Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat

Markers in Region
RH140025  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2960,536,635 - 60,536,840 (+)MAPPERmRatBN7.2
Rnor_6.0965,885,351 - 65,885,555NCBIRnor6.0
Rnor_5.0965,692,048 - 65,692,252UniSTSRnor5.0
RGSC_v3.4957,663,807 - 57,664,011UniSTSRGSC3.4
Celera957,975,564 - 57,975,768UniSTS
RH 3.4 Map9494.8UniSTS
Cytogenetic Map9q31UniSTS
AI105082  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2960,569,412 - 60,569,513 (+)MAPPERmRatBN7.2
Rnor_6.0965,917,596 - 65,917,696NCBIRnor6.0
Rnor_5.0965,724,829 - 65,724,929UniSTSRnor5.0
RGSC_v3.4957,696,622 - 57,696,722UniSTSRGSC3.4
Celera958,007,447 - 58,007,547UniSTS
RH 3.4 Map9475.59UniSTS
Cytogenetic Map9q31UniSTS
AI176040  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2960,568,442 - 60,568,602 (+)MAPPERmRatBN7.2
Rnor_6.0965,916,626 - 65,916,785NCBIRnor6.0
Rnor_5.0965,723,859 - 65,724,018UniSTSRnor5.0
RGSC_v3.4957,695,652 - 57,695,811UniSTSRGSC3.4
Celera958,006,477 - 58,006,636UniSTS
RH 3.4 Map9494.69UniSTS
Cytogenetic Map9q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 70 14 31 4
Low 3 43 57 41 19 41 8 11 4 21 10 7 8
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000031866   ⟹   ENSRNOP00000036108
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl960,536,531 - 60,568,949 (-)Ensembl
Rnor_6.0 Ensembl965,885,246 - 65,917,132 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000077483   ⟹   ENSRNOP00000074197
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl960,535,233 - 60,568,591 (-)Ensembl
Rnor_6.0 Ensembl965,882,054 - 65,916,949 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000119394   ⟹   ENSRNOP00000078512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl960,535,233 - 60,572,567 (-)Ensembl
RefSeq Acc Id: NM_001108220   ⟹   NP_001101690
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,030,664 - 68,063,082 (-)NCBI
mRatBN7.2960,536,531 - 60,568,949 (-)NCBI
Rnor_6.0965,885,246 - 65,917,132 (-)NCBI
Rnor_5.0965,688,765 - 65,725,024 (-)NCBI
RGSC_v3.4957,663,702 - 57,696,158 (-)RGD
Celera957,975,459 - 58,006,983 (-)RGD
Sequence:
RefSeq Acc Id: XM_006244975   ⟹   XP_006245037
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,027,481 - 68,063,876 (-)NCBI
mRatBN7.2960,533,348 - 60,569,062 (-)NCBI
Rnor_6.0965,882,063 - 65,917,094 (-)NCBI
Rnor_5.0965,688,765 - 65,725,024 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006244977   ⟹   XP_006245039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,027,481 - 68,066,731 (-)NCBI
mRatBN7.2960,533,348 - 60,568,712 (-)NCBI
Rnor_6.0965,882,063 - 65,916,804 (-)NCBI
Rnor_5.0965,688,765 - 65,725,024 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039083614   ⟹   XP_038939542
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,027,481 - 68,063,876 (-)NCBI
mRatBN7.2960,533,348 - 60,569,062 (-)NCBI
RefSeq Acc Id: XM_039083615   ⟹   XP_038939543
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,034,382 - 68,063,876 (-)NCBI
mRatBN7.2960,540,249 - 60,569,062 (-)NCBI
RefSeq Acc Id: XM_039083616   ⟹   XP_038939544
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,027,481 - 68,063,876 (-)NCBI
mRatBN7.2960,537,008 - 60,569,062 (-)NCBI
RefSeq Acc Id: XM_039083617   ⟹   XP_038939545
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,027,481 - 68,063,876 (-)NCBI
mRatBN7.2960,537,016 - 60,569,062 (-)NCBI
RefSeq Acc Id: XM_063267179   ⟹   XP_063123249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,027,481 - 68,061,410 (-)NCBI
RefSeq Acc Id: XM_063267180   ⟹   XP_063123250
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,041,974 - 68,063,876 (-)NCBI
RefSeq Acc Id: XR_005488910
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,031,248 - 68,063,876 (-)NCBI
mRatBN7.2960,533,348 - 60,569,062 (-)NCBI
RefSeq Acc Id: NP_001101690   ⟸   NM_001108220
- UniProtKB: A6IP94 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245037   ⟸   XM_006244975
- Peptide Label: isoform X1
- UniProtKB: D3ZAP8 (UniProtKB/TrEMBL),   A0A8I6G323 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006245039   ⟸   XM_006244977
- Peptide Label: isoform X2
- UniProtKB: A0A0G2K7G5 (UniProtKB/TrEMBL),   A0A8I6G323 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000036108   ⟸   ENSRNOT00000031866
RefSeq Acc Id: ENSRNOP00000074197   ⟸   ENSRNOT00000077483
RefSeq Acc Id: XP_038939542   ⟸   XM_039083614
- Peptide Label: isoform X3
- UniProtKB: A0A8I6G323 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038939544   ⟸   XM_039083616
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038939545   ⟸   XM_039083617
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038939543   ⟸   XM_039083615
- Peptide Label: isoform X5
RefSeq Acc Id: ENSRNOP00000078512   ⟸   ENSRNOT00000119394
RefSeq Acc Id: XP_063123249   ⟸   XM_063267179
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063123250   ⟸   XM_063267180
- Peptide Label: isoform X5

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-A0A0G2K7G5-F1-model_v2 AlphaFold A0A0G2K7G5 1-403 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696698
Promoter ID:EPDNEW_R7223
Type:multiple initiation site
Name:Tmem237_1
Description:transmembrane protein 237
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7224  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0965,916,797 - 65,916,857EPDNEW
RGD ID:13696699
Promoter ID:EPDNEW_R7224
Type:single initiation site
Name:Tmem237_2
Description:transmembrane protein 237
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7223  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0965,917,115 - 65,917,175EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306705 AgrOrtholog
BioCyc Gene G2FUF-27419 BioCyc
Ensembl Genes ENSRNOG00000024085 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000031866.5 UniProtKB/TrEMBL
  ENSRNOT00000077483.2 UniProtKB/TrEMBL
  ENSRNOT00000119394.1 UniProtKB/TrEMBL
InterPro TMEM237 UniProtKB/TrEMBL
KEGG Report rno:316412 UniProtKB/TrEMBL
NCBI Gene 316412 ENTREZGENE
PANTHER PTHR28388 UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 237 UniProtKB/TrEMBL
Pfam TMEM237 UniProtKB/TrEMBL
PhenoGen Tmem237 PhenoGen
RatGTEx ENSRNOG00000024085 RatGTEx
UniProt A0A0G2K7G5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6G323 ENTREZGENE, UniProtKB/TrEMBL
  A6IP94 ENTREZGENE, UniProtKB/TrEMBL
  D3ZAP8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-07-28 Tmem237  transmembrane protein 237  Als2cr4  amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Als2cr4  amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4   Als2cr4_predicted  amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Als2cr4_predicted  amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 4 (predicted)      Symbol and Name status set to approved 70820 APPROVED