Exosc2 (exosome component 2) - Rat Genome Database

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Gene: Exosc2 (exosome component 2) Rattus norvegicus
Analyze
Symbol: Exosc2
Name: exosome component 2
RGD ID: 1306573
Description: Predicted to enable RNA binding activity. Predicted to be involved in RNA metabolic process and positive regulation of cell growth. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Human ortholog(s) of this gene implicated in short stature, hearing loss, retinitis pigmentosa, and distinctive facies. Orthologous to human EXOSC2 (exosome component 2); PARTICIPATES IN RNA degradation pathway; INTERACTS WITH 17beta-estradiol; 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: exosome complex component RRP4; exosome complex exonuclease RRP4; LOC366017
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8335,360,652 - 35,370,948 (+)NCBIGRCr8
mRatBN7.2314,962,930 - 14,973,645 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl314,962,917 - 14,973,575 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,036,215 - 18,046,468 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0326,621,221 - 26,631,474 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0324,868,310 - 24,878,557 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0310,151,734 - 10,161,997 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl310,151,284 - 10,161,989 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0315,511,096 - 15,521,359 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4310,786,985 - 10,797,248 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1310,683,157 - 10,693,688 (+)NCBI
Celera39,711,298 - 9,721,560 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
afimoxifene  (ISO)
all-trans-retinoic acid  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
chromium(6+)  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
coumestrol  (ISO)
cylindrospermopsin  (ISO)
deoxynivalenol  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
flutamide  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
FR900359  (ISO)
indole-3-methanol  (EXP)
inulin  (ISO)
isobutanol  (ISO)
ivermectin  (ISO)
maneb  (ISO)
methidathion  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PCB138  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
resveratrol  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12419256   PMID:17174896   PMID:17545563   PMID:20531389   PMID:25931508   PMID:26166824  


Genomics

Comparative Map Data
Exosc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8335,360,652 - 35,370,948 (+)NCBIGRCr8
mRatBN7.2314,962,930 - 14,973,645 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl314,962,917 - 14,973,575 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx318,036,215 - 18,046,468 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0326,621,221 - 26,631,474 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0324,868,310 - 24,878,557 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0310,151,734 - 10,161,997 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl310,151,284 - 10,161,989 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0315,511,096 - 15,521,359 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4310,786,985 - 10,797,248 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1310,683,157 - 10,693,688 (+)NCBI
Celera39,711,298 - 9,721,560 (+)NCBICelera
Cytogenetic Map3p12NCBI
EXOSC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389130,693,760 - 130,704,894 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9130,693,721 - 130,707,288 (+)EnsemblGRCh38hg38GRCh38
GRCh379133,569,147 - 133,580,281 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369132,558,998 - 132,570,077 (+)NCBINCBI36Build 36hg18NCBI36
Build 349130,598,730 - 130,609,808NCBI
Celera9104,107,689 - 104,118,983 (+)NCBICelera
Cytogenetic Map9q34.12NCBI
HuRef9103,055,772 - 103,067,067 (+)NCBIHuRef
CHM1_19133,718,191 - 133,729,489 (+)NCBICHM1_1
T2T-CHM13v2.09142,898,712 - 142,909,846 (+)NCBIT2T-CHM13v2.0
Exosc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39231,560,727 - 31,571,593 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl231,560,727 - 31,571,361 (+)EnsemblGRCm39 Ensembl
GRCm38231,670,715 - 31,681,352 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl231,670,715 - 31,681,349 (+)EnsemblGRCm38mm10GRCm38
MGSCv37231,526,257 - 31,536,840 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36231,492,745 - 31,503,329 (+)NCBIMGSCv36mm8
Celera231,371,398 - 31,381,973 (+)NCBICelera
Cytogenetic Map2BNCBI
cM Map221.86NCBI
Exosc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955513639,731 - 651,418 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955513639,798 - 648,360 (+)NCBIChiLan1.0ChiLan1.0
EXOSC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2118,645,017 - 8,658,268 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan198,647,358 - 8,660,558 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09101,815,368 - 101,826,464 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19130,464,487 - 130,475,719 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9130,464,487 - 130,475,719 (+)Ensemblpanpan1.1panPan2
EXOSC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1953,266,396 - 53,276,236 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl953,266,401 - 53,276,677 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha952,464,948 - 52,475,561 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0954,165,433 - 54,176,045 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl954,166,710 - 54,176,018 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1952,942,940 - 52,953,572 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0953,263,746 - 53,274,359 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0953,356,968 - 53,367,401 (-)NCBIUU_Cfam_GSD_1.0
Exosc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947197,906,868 - 197,918,427 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648717,675,303 - 17,687,943 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648717,675,401 - 17,686,224 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EXOSC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1270,748,537 - 270,758,111 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11270,748,534 - 270,757,717 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21304,671,187 - 304,680,415 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EXOSC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1127,441,812 - 7,452,979 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl127,442,791 - 7,452,964 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660798,011,684 - 8,022,863 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Exosc2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247605,035,663 - 5,044,549 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247605,036,185 - 5,044,504 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Exosc2
37 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:352
Count of miRNA genes:199
Interacting mature miRNAs:232
Transcripts:ENSRNOT00000012312
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat

Markers in Region
BF387046  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2314,971,524 - 14,971,689 (-)MAPPERmRatBN7.2
Rnor_6.0310,153,240 - 10,153,404NCBIRnor6.0
Rnor_5.0315,512,602 - 15,512,766UniSTSRnor5.0
RGSC_v3.4310,795,578 - 10,795,742UniSTSRGSC3.4
Celera39,719,889 - 9,720,053UniSTS
Cytogenetic Map3p12UniSTS
BE107032  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2314,973,017 - 14,973,174 (-)MAPPERmRatBN7.2
Rnor_6.0310,151,755 - 10,151,911NCBIRnor6.0
Rnor_5.0315,511,117 - 15,511,273UniSTSRnor5.0
RGSC_v3.4310,797,071 - 10,797,227UniSTSRGSC3.4
Celera39,721,383 - 9,721,539UniSTS
RH 3.4 Map356.0UniSTS
Cytogenetic Map3p12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 26 27 18 18 18 1 1 74 23 35 11 1
Low 17 30 23 1 23 7 10 12 6 7
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000012312   ⟹   ENSRNOP00000012311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl314,962,947 - 14,973,575 (+)Ensembl
Rnor_6.0 Ensembl310,151,284 - 10,161,989 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093246   ⟹   ENSRNOP00000076189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl310,153,166 - 10,153,554 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093494
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl310,156,867 - 10,161,989 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093692
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl314,962,917 - 14,971,079 (+)Ensembl
Rnor_6.0 Ensembl310,153,755 - 10,161,989 (-)Ensembl
RefSeq Acc Id: NM_001108952   ⟹   NP_001102422
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8335,360,666 - 35,370,929 (+)NCBI
mRatBN7.2314,962,930 - 14,973,195 (+)NCBI
Rnor_6.0310,151,734 - 10,161,997 (-)NCBI
Rnor_5.0315,511,096 - 15,521,359 (-)NCBI
RGSC_v3.4310,786,985 - 10,797,248 (+)RGD
Celera39,711,298 - 9,721,560 (+)RGD
Sequence:
RefSeq Acc Id: XM_039105586   ⟹   XP_038961514
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8335,362,057 - 35,370,948 (+)NCBI
mRatBN7.2314,964,305 - 14,973,645 (+)NCBI
RefSeq Acc Id: XM_063284261   ⟹   XP_063140331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8335,360,652 - 35,369,890 (+)NCBI
Protein Sequences
Protein RefSeqs NP_001102422 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961514 (Get FASTA)   NCBI Sequence Viewer  
  XP_063140331 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL93269 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000012311
  ENSRNOP00000012311.3
  ENSRNOP00000076582.1
Reference Protein Sequences
RefSeq Acc Id: NP_001102422   ⟸   NM_001108952
- UniProtKB: D3ZBP3 (UniProtKB/TrEMBL),   A6JU28 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000012311   ⟸   ENSRNOT00000012312
RefSeq Acc Id: ENSRNOP00000076189   ⟸   ENSRNOT00000093246
RefSeq Acc Id: XP_038961514   ⟸   XM_039105586
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063140331   ⟸   XM_063284261
- Peptide Label: isoform X1
Protein Domains
Exosome complex component N-terminal   K Homology   RRP4 S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZBP3-F1-model_v2 AlphaFold D3ZBP3 1-293 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691973
Promoter ID:EPDNEW_R2498
Type:single initiation site
Name:Exosc2_1
Description:exosome component 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0310,161,989 - 10,162,049EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1306573 AgrOrtholog
BioCyc Gene G2FUF-50173 BioCyc
Ensembl Genes ENSRNOG00000009245 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000012312 ENTREZGENE
  ENSRNOT00000012312.7 UniProtKB/TrEMBL
  ENSRNOT00000093692.2 UniProtKB/TrEMBL
Gene3D-CATH 2.40.50.100 UniProtKB/TrEMBL
  2.40.50.140 UniProtKB/TrEMBL
InterPro Exosome_cplx_N_dom UniProtKB/TrEMBL
  Exosome_RNA_bind1/RRP40/RRP4 UniProtKB/TrEMBL
  KH_dom_type_1 UniProtKB/TrEMBL
  KH_dom_type_1_sf UniProtKB/TrEMBL
  NA-bd_OB-fold UniProtKB/TrEMBL
  RRP4_S1 UniProtKB/TrEMBL
KEGG Report rno:366017 UniProtKB/TrEMBL
NCBI Gene 366017 ENTREZGENE
PANTHER EXOSOME COMPLEX COMPONENT RRP4 UniProtKB/TrEMBL
  PTHR21321 UniProtKB/TrEMBL
Pfam ECR1_N UniProtKB/TrEMBL
  KH_6 UniProtKB/TrEMBL
  RRP4_S1 UniProtKB/TrEMBL
PhenoGen Exosc2 PhenoGen
RatGTEx ENSRNOG00000009245 RatGTEx
Superfamily-SCOP Ribosomal L27 protein-like UniProtKB/TrEMBL
  SSF50249 UniProtKB/TrEMBL
  SSF54791 UniProtKB/TrEMBL
UniProt A0A8I5Y5D3_RAT UniProtKB/TrEMBL
  A6JU28 ENTREZGENE, UniProtKB/TrEMBL
  D3ZBP3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-04-30 Exosc2  exosome component 2   Exosc2_predicted  exosome component 2 (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Exosc2_predicted  exosome component 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED