Clec14a (C-type lectin domain containing 14A)

Gene: Clec14a (C-type lectin domain containing 14A) Rattus norvegicus

Analyze

Symbol:

Clec14a

Name:

C-type lectin domain containing 14A

RGD ID:

1306232

Description:

Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Predicted to be involved in cell migration involved in sprouting angiogenesis. Predicted to act upstream of or within with a positive effect on vascular endothelial growth factor receptor-3 signaling pathway. Predicted to act upstream of or within with a negative effect on vascular endothelial growth factor receptor-2 signaling pathway. Predicted to act upstream of or within lymphangiogenesis and sprouting angiogenesis. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC14A (C-type lectin domain containing 14A); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

C-type lectin domain family 14 member A; C-type lectin domain family 14, member A; LOC314148; RGD1306232; similar to RIKEN cDNA 1200003C23

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	81,616,414 - 81,619,556 (-)	NCBI		GRCr8
mRatBN7.2	6	75,881,470 - 75,884,612 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	75,881,473 - 75,884,612 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	76,290,931 - 76,294,072 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	76,590,282 - 76,593,423 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	76,017,735 - 76,020,876 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	79,303,301 - 79,306,443 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	79,303,304 - 79,306,443 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	88,832,646 - 88,835,788 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	78,851,636 - 78,854,778 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	78,854,764 - 78,857,904 (-)	NCBI
Celera	6	74,652,586 - 74,655,728 (-)	NCBI		Celera
Cytogenetic Map	6	q23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Brain-Lung-Thyroid Syndrome (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3,7-dihydropurine-6-thione (EXP)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

aconitine (EXP)

acrylamide (ISO)

aflatoxin B1 (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

arsenite(3-) (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

cobalt dichloride (ISO)

endosulfan (EXP)

fipronil (EXP)

flutamide (EXP)

fonofos (ISO)

levofloxacin (EXP)

mercaptopurine (EXP)

oxaliplatin (EXP)

ozone (ISO)

parathion (ISO)

phenethyl isothiocyanate (EXP)

phenobarbital (ISO)

pioglitazone (ISO)

pirinixic acid (ISO)

poly(I:C) (EXP)

propiconazole (EXP)

purine-6-thiol (EXP)

sulfadimethoxine (EXP)

terbufos (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

topotecan (EXP)

tremolite asbestos (ISO)

triadimefon (EXP)

troglitazone (EXP)

valdecoxib (EXP)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cell migration (IBA)

cell migration involved in sprouting angiogenesis (ISO)

lymphangiogenesis (ISO)

sprouting angiogenesis (ISO)

vascular endothelial growth factor receptor-2 signaling pathway (ISO)

vascular endothelial growth factor receptor-3 signaling pathway (ISO)

Cellular Component

external side of plasma membrane (IBA,ISO)

extracellular matrix (IEA)

Molecular Function

extracellular matrix binding (IBA)

extracellular matrix protein binding (IBA,ISO)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:23376485	PMID:23979707	PMID:25745997	PMID:27991863

Genomics

Comparative Map Data

Clec14a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	6	81,616,414 - 81,619,556 (-)	NCBI		GRCr8
mRatBN7.2	6	75,881,470 - 75,884,612 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	6	75,881,473 - 75,884,612 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	6	76,290,931 - 76,294,072 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	6	76,590,282 - 76,593,423 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	6	76,017,735 - 76,020,876 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	6	79,303,301 - 79,306,443 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	6	79,303,304 - 79,306,443 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	6	88,832,646 - 88,835,788 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	6	78,851,636 - 78,854,778 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	6	78,854,764 - 78,857,904 (-)	NCBI
Celera	6	74,652,586 - 74,655,728 (-)	NCBI		Celera
Cytogenetic Map	6	q23	NCBI

CLEC14A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	14	38,254,000 - 38,256,093 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	14	38,254,000 - 38,256,093 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	14	38,723,205 - 38,725,298 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	14	37,793,070 - 37,795,325 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	14	18,587,840 - 18,590,095 (-)	NCBI		Celera
Cytogenetic Map	14	q21.1	NCBI
HuRef	14	18,838,180 - 18,840,550 (-)	NCBI		HuRef
CHM1_1	14	38,720,965 - 38,723,335 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	14	32,442,690 - 32,444,783 (-)	NCBI		T2T-CHM13v2.0

Clec14a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	12	58,311,506 - 58,316,044 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	12	58,311,506 - 58,316,076 (-)	Ensembl		GRCm39 Ensembl
GRCm38	12	58,264,720 - 58,269,258 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	12	58,264,720 - 58,269,290 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	12	59,365,707 - 59,370,245 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	12	59,182,732 - 59,186,900 (-)	NCBI		MGSCv36	mm8
Celera	12	59,419,185 - 59,423,723 (-)	NCBI		Celera
Cytogenetic Map	12	C1	NCBI
cM Map	12	25.65	NCBI

Clec14a
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955409	22,819,530 - 22,823,306 (+)	NCBI	ChiLan1.0	ChiLan1.0

CLEC14A
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	15	39,577,819 - 39,581,718 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	14	38,794,323 - 38,798,228 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	14	19,014,672 - 19,018,551 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	14	37,374,049 - 37,376,621 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	14	37,374,493 - 37,375,965 (-)	Ensembl	panpan1.1		panPan2

CLEC14A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	8	16,609,425 - 16,612,772 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	8	16,611,240 - 16,612,709 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	8	16,414,773 - 16,418,124 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	8	16,725,500 - 16,728,851 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	8	16,419,013 - 16,422,364 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	8	16,477,258 - 16,480,609 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	8	16,777,896 - 16,781,247 (-)	NCBI		UU_Cfam_GSD_1.0

Clec14a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	48,606,360 - 48,609,975 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936494	12,114,371 - 12,115,787 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936494	12,112,163 - 12,115,836 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CLEC14A
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	7	61,826,015 - 61,832,808 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	7	61,825,688 - 61,827,960 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	7	66,528,722 - 66,531,458 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CLEC14A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	24	15,047,320 - 15,051,145 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	24	15,048,214 - 15,049,689 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666053	4,078,490 - 4,081,871 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Clec14a
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624813	7,635,808 - 7,637,169 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624813	7,635,356 - 7,637,300 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Clec14a
5 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	41
Count of miRNA genes:	37
Interacting mature miRNAs:	41
Transcripts:	ENSRNOT00000030706
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
4145119	Mcs25	Mammary carcinoma susceptibility QTL 25		0.0001	mammary gland integrity trait (VT:0010552)	ratio of deaths to total study population during a period of time (CMO:0001023)	6	10894415	110548006	Rat
1576309	Emca7	Estrogen-induced mammary cancer QTL 7	4		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	15107216	107351382	Rat
2293839	Kiddil2	Kidney dilation QTL 2	4.8		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
2293841	Kiddil4	Kidney dilation QTL 4	4.4		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	6	20866422	81133036	Rat
6893340	Cm77	Cardiac mass QTL 77	0.26	0.57	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	33309549	81132889	Rat
1300143	Rf14	Renal function QTL 14	2.92		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	6	34434137	77102317	Rat
634307	Bp141	Blood pressure QTL 141	4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	35230417	80230417	Rat
9590290	Uminl2	Urine mineral level QTL 2	3.96	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	6	38783989	83783989	Rat
9590306	Scort18	Serum corticosterone level QTL 18	2.88	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat
9590140	Scort4	Serum corticosterone level QTL 4	14.49	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	6	38783989	83783989	Rat
634330	Pia16	Pristane induced arthritis QTL 16	3.9		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	6	45790088	104200226	Rat
4889848	Pur25	Proteinuria QTL 25	14	0.003	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	56728562	90198260	Rat
6893332	Cm74	Cardiac mass QTL 74	0.4	0.64	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	6	57730540	104085867	Rat
1558641	Cm47	Cardiac mass QTL 47	2.9	0.001	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	6	57730540	104085867	Rat
70176	Mcsm1	Mammary carcinoma susceptibility modifier QTL 1			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	6	58632962	103632962	Rat
12801471	Schws9	Schwannoma susceptibility QTL 9			nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	6	61747639	106747639	Rat
731173	Uae22	Urinary albumin excretion QTL 22	10.1		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
2290393	Uae37	Urinary albumin excretion QTL 37		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	65531555	140994061	Rat
1641904	Alcrsp4	Alcohol response QTL 4			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	6	67262953	112262953	Rat
1300075	Glom7	Glomerulus QTL 7	5.6	0.0000002	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	6	71201409	116201409	Rat
1331789	Rf37	Renal function QTL 37	3.224		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	6	72202632	115200186	Rat
70196	BpQTLcluster7	Blood pressure QTL cluster 7	6.82		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	72202632	117202632	Rat
724536	Uae7	Urinary albumin excretion QTL 7	3.5		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	6	72202632	130729475	Rat
1331799	Bp211	Blood pressure QTL 211	3.66407		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	6	72202632	130919985	Rat
2301964	Bp323	Blood pressure QTL 323	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	6	72227641	81132889	Rat
1581550	Pur8	Proteinuria QTL 8			urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	6	72227641	130729205	Rat
1581563	Uae33	Urinary albumin excretion QTL 33			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	72227641	130729205	Rat
724524	Uae2	Urinary albumin excretion QTL 2	2.7	0.0005	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	6	73463459	109394713	Rat

Markers in Region

AI170389

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	6	75,881,766 - 75,882,010 (+)	MAPPER	mRatBN7.2
Rnor_6.0	6	79,303,598 - 79,303,841	NCBI	Rnor6.0
Rnor_5.0	6	88,832,943 - 88,833,186	UniSTS	Rnor5.0
RGSC_v3.4	6	78,851,933 - 78,852,176	UniSTS	RGSC3.4
Celera	6	74,652,883 - 74,653,126	UniSTS
RH 3.4 Map	6	546.5	UniSTS
Cytogenetic Map	6	q23	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	21	21	13	10	13	1	1		30	31	11	1
Low		22	36	28	9	28	7	10	74	5	9		7
Below cutoff											1

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014077	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC098459	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC081897	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473947	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000006	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000030706 ⟹ ENSRNOP00000038701

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	6	75,881,473 - 75,884,612 (-)	Ensembl
Rnor_6.0 Ensembl	6	79,303,304 - 79,306,443 (-)	Ensembl

RefSeq Acc Id:

NM_001014077 ⟹ NP_001014099

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	6	81,616,414 - 81,619,556 (-)	NCBI
mRatBN7.2	6	75,881,470 - 75,884,612 (-)	NCBI
Rnor_6.0	6	79,303,301 - 79,306,443 (-)	NCBI
Rnor_5.0	6	88,832,646 - 88,835,788 (-)	NCBI
RGSC_v3.4	6	78,851,636 - 78,854,778 (-)	RGD
Celera	6	74,652,586 - 74,655,728 (-)	RGD

Sequence:

show sequence

CGGCAAGCCAGAGAACTTGGGAGCAGCTGTGGGCTCTTGAGTCTCCAGGATGAGGCCGGCTCTT
GCCCTGTGCCTCCTCTGTCCTGCGTTCTGGCCCCGGCCAGGGAATGGCGAGCACCCCACGGCCG
ATCGCGCAGTTTGTTCGGTCCCGGGGGCTTGCTACAGCCTGCACCACGCAGCCATGAAGAGGAG
GGCGGCGGAGGAGGCCTGTAGCTTGCGCGGCGGGACTCTCAGCACCGTGCAGTCCGGCTCTGAG
TTGCAAGCTGTGCTCAAGCTCTTTCGTGCAGGTCCCGGGCCTGGTGGAGGCTCCAAAGACCTAA
TGTTCTGGGTGGCTCTGGAGCGTGACCGTTCACAGTGCACCCAGGAGAGAGAGCCTTTGAGGGG
TTTCTCCTGGTTGTACACGGACTCAGAAGACTCGGAGAACAGAACACTACCTTGGGTGGAAGAG
CCACAACTTTCTTGCACTGTACGAAAGTGCGCTGTGCTCCAGGCCACCGGGGGAGTGGAGCCTG
CTGGCTGGAAGGAGATGCGCTGTCAACAGCGCGCCGATGGCTACCTGTGCAAGTACCAGTTTGA
GGCTCTGTGCCCTGCGCCTCGCCCGGGAGCCGCCTCTAACTTAAGTTTCCAAGCTCCCTTCCGG
CTGAGCAGTTCTGCCCTGGACTTCAGCCCTCCTGGGACCGAGGTGAGTGCGATGTGTCCCAGGG
ACTTCTCAGTCTCCTCCATCTGCGTCCAGGAAGAGACAGGCGCACGCTGGGATGGGCTTTTCCC
TGGGAGCTTGCTCTGCCCCTGTTCTGGGAGGTACCTCCTTGCTGGCAAGTGCGTGGAGCTCGCT
GACTGCCTAGACTACTTGGGAAACTTCGCCTGCGAATGTGCTGTGGGTTTTGAGCTAGGGAAGG
ACAAACGCTCTTGTGAGACCAAAGCGGAAGGCCAACTAACCCTCGAGGGGACCAAGTTGCCCAC
TAGAAATGTATCAGCCACTCCAGCCAGTCCTGTGACAAACAAATCGTGGCCAGGTCAGGTCTAT
GACAAGCCAGGAGAGATGCCCCAGGTCACTGGACAAGACCGTATTGCGACATCTGTTCCTGAGA
TTCTTCAGTGGGGAACACAGAGTACTTTACCTACTGTTCAAACGTCCCCACAAACCAAGCCAAA
AGTCACCATCACACCATCAGGAAGTATGATGCCCACATTGAACTTCGCATCTTCCCCTCCTGTT
TCTCTGACTTTCGACTCCTCCTCCACGGTGGTCTTCGTACTTGTGAGCATAGCAGTAATAGTTT
TGGTACTCTTGACCATTACAGTGCTGGGACTTTTCAAACTCTGCTTCCACAAAAGCCCTTCCTC
CAGGACAAGGAAGGGAGCTTTGGACTCACAGGGTGTGGAATGTGATGCAGAGGCCACCTCTCTG
CGGCACAATTCTGCACAGTGCACGGACACTGGAGGGAAGGGTGCCTGAGGGGCTGAGCTGAGGG
CACTTCACTAGTTGGGTTCTCTCTTGGATCAGGACACACTTAGGGAAACAGCCCAATGCCCACA
TCTTGTCTAGATTTTTTTCAGTTCCAACAATTGGGAAAAGAAGGGATTTTGCAATGATGATTAC
TTTGGAAGTTCCCCTTCCCATAAATTCTCTTTTTTTTCCACTAAGGAGCTAAATCTGAAAGTCA
CACTAGTCCCCTGAAGGTGAAGAGGGGGAGGCTATGGACTGGTGGAGCACAGGATGGCAAATGG
CAGGAGGCGGTTTTCTGTGTTCTGAGGGAATTTGGAGAAGTGCTTGTATATTTCCCAGTCTTGG
GAACAAATAAATAAATAACACTATAATTTTTGGAACGTTTACTTTCACCCAAAATGAAAAAGGA
AATAGCTATATTATTCAGGCTAGGAATATATTAGCTTGAAAATTTCAGGTAAATAATAAAACAT
CGCTGAGAACCCAGACTAATATGTTTGACTTATGCAAAGGGTGTTCTTTAGGAGTACAACGTTC
TGGAGATAGCAACTGGCTATGGGGTATGCTGGGAAGACACACAGAAGTAAACGCTGGTGTTTTG
AGGGGAAGTCCTTATACCCTAGCTCCTTCAGAACTAGTGAAGTTTCCCTTTATTCTTTTATCCT
TTGCTTTCAAAGTCACTGGGACTGTGCTCTGCTATAAATCCTAAGTGCAAGGTTGCCAGTTTCT
GACTCTAGAAGCAAATTACAGTTGACCACCAATCCAAGTGTTTACTGTGTGTCCTTGCCCAAGG
AAACAAATGATTTGTGTCTTCGTTTTCCAATGTTTGTGTTCTCCAGTGTAATGACCTTCCTCTC
CAAGCCACCTTGTAGACATCAAGATGCTGATCCTCACTTCCAATTACGATGATGTTAATTCTCA
ATTAAAACGTTAATGCTAAGTATTGATTTGAAATCTTCTGGGTGCATTAAAGCAAAAGGAAGCT
TGGCTTCTTCCAAAGTTGCAAGATTCTTGTGCCCTATTTAATCCATGAGGGTGGGGGTGGGGAC
ACTTGAATGTCAACCCATTTCTGTTTCTTCTCAATAGATTGTGAATGCAATGACAATGTGTGAG
TATCAGGGGATTGTTACAACTGCACAAGAGTCTTAGCAGGCAAAACTGCAGGAAATGGCTTTCT
GCAGAATTAATAGTGTAAAAAAGAAATAATAAATAAAACCTAACATCTTGTTATGACTTGAGAT
GTTAGCATATAATAAAAAAAAATCACACATTCAGGTGGTAAATAATTAAGGCATAATAATAATA
ATAATATCTGGTTGAATTCAAAGACCTTGGAGAATATTTCAGTTAGAGTGCTGAGATTTTTGTA
AGTGTTGTAAAGTTGTTGTGTGAAGGGAAATAGAGAAATAAACTTACTTGTGGGAGAAAATGAA
AGTAGAAAAAACTTGGACTATATTTTTCTAGAATCATTTTTATACTCTTGATTGTACTAAGAGT
TGATTTAATGTTAGCAAATAACCAATAATAAAATAACCTAGAAAATTAAGAGAGTTCAATATAT
GAATCTGTGTTTTAAATATAAATCTACGTGCTTAATATTGTATCACTGAAGGGAAAAATTGATA
GAAAGCTTGCTTCATAAGTTGAATATGGCTTTAAATAGTTACAGTTAAATAAAATCACAAATGA
ATTCAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001014099	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH81897	(Get FASTA)	NCBI Sequence Viewer
	EDM03460	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000038701
	ENSRNOP00000038701.4

RefSeq Acc Id:	NP_001014099 ⟸ NM_001014077
- Peptide Label:	precursor
- UniProtKB:	Q642B4 (UniProtKB/TrEMBL), F7FMP6 (UniProtKB/TrEMBL)
- Sequence:	show sequence MRPALALCLLCPAFWPRPGNGEHPTADRAVCSVPGACYSLHHAAMKRRAAEEACSLRGGTLSTV QSGSELQAVLKLFRAGPGPGGGSKDLMFWVALERDRSQCTQEREPLRGFSWLYTDSEDSENRTL PWVEEPQLSCTVRKCAVLQATGGVEPAGWKEMRCQQRADGYLCKYQFEALCPAPRPGAASNLSF QAPFRLSSSALDFSPPGTEVSAMCPRDFSVSSICVQEETGARWDGLFPGSLLCPCSGRYLLAGK CVELADCLDYLGNFACECAVGFELGKDKRSCETKAEGQLTLEGTKLPTRNVSATPASPVTNKSW PGQVYDKPGEMPQVTGQDRIATSVPEILQWGTQSTLPTVQTSPQTKPKVTITPSGSMMPTLNFA SSPPVSLTFDSSSTVVFVLVSIAVIVLVLLTITVLGLFKLCFHKSPSSRTRKGALDSQGVECDA EATSLRHNSAQCTDTGGKGA hide sequence

RefSeq Acc Id:

ENSRNOP00000038701 ⟸ ENSRNOT00000030706

Protein Domains

C-type lectin

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q642B4-F1-model_v2	AlphaFold	Q642B4	1-468	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694612

Promoter ID:

EPDNEW_R5137

Type:

initiation region

Name:

Clec14a_1

Description:

C-type lectin domain containing 14A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	6	79,306,462 - 79,306,522	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1306232	AgrOrtholog
BioCyc Gene	G2FUF-37400	BioCyc
Ensembl Genes	ENSRNOG00000022697	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000030706	ENTREZGENE
	ENSRNOT00000030706.6	UniProtKB/TrEMBL
Gene3D-CATH	3.10.100.10	UniProtKB/TrEMBL
	Laminin	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7110446	IMAGE-MGC_LOAD
InterPro	C-type_lectin	UniProtKB/TrEMBL
	C-type_lectin-like	UniProtKB/TrEMBL
	C-type_lectin_fold	UniProtKB/TrEMBL
KEGG Report	rno:314148	UniProtKB/TrEMBL
MGC_CLONE	MGC:93813	IMAGE-MGC_LOAD
NCBI Gene	314148	ENTREZGENE
PANTHER	C-TYPE LECTIN DOMAIN FAMILY 14 MEMBER A	UniProtKB/TrEMBL
	CHONDROLECTIN VARIANT CHODLFDELTAE	UniProtKB/TrEMBL
PhenoGen	Clec14a	PhenoGen
PROSITE	C_TYPE_LECTIN_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000022697	RatGTEx
SMART	CLECT	UniProtKB/TrEMBL
Superfamily-SCOP	C-type_lectin_fold	UniProtKB/TrEMBL
	EGF/Laminin	UniProtKB/TrEMBL
UniProt	F7FMP6	ENTREZGENE, UniProtKB/TrEMBL
	Q642B4	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2017-03-29	Clec14a	C-type lectin domain containing 14A	Clec14a	C-type lectin domain family 14, member A	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-06-08	Clec14a	C-type lectin domain family 14, member A	Clec14a	C-type lectin domain family 14, member a	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Clec14a	C-type lectin domain family 14, member a	RGD1306232	similar to RIKEN cDNA 1200003C23	Symbol and Name updated	1299863	APPROVED
2005-12-06	RGD1306232	similar to RIKEN cDNA 1200003C23	RGD1306232_predicted	similar to RIKEN cDNA 1200003C23 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1306232_predicted	similar to RIKEN cDNA 1200003C23 (predicted)	LOC314148_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC314148_predicted	similar to RIKEN cDNA 1200003C23 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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