Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (1->4)-beta-D-glucan | multiple interactions | ISO | Msrb2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MSRB2 mRNA | CTD | PMID:36331819 | 1,1-dichloroethene | decreases expression | ISO | Msrb2 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of MSRB2 mRNA | CTD | PMID:26682919 | 1,2-dimethylhydrazine | decreases expression | ISO | Msrb2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of MSRB2 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Msrb2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MSRB2 mRNA | CTD | PMID:22206623 | 1,3-dinitrobenzene | decreases expression | EXP | | 6480464 | 3-dinitrobenzene results in decreased expression of MSRB2 mRNA | CTD | PMID:21983209 | 1,4-dithiothreitol | increases reduction | ISO | MSRB2 (Homo sapiens) | 6480464 | Dithiothreitol results in increased reduction of MSRB2 protein | CTD | PMID:16735467 | 17alpha-ethynylestradiol | increases expression | ISO | Msrb2 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of MSRB2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | ISO | Msrb2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MSRB2 mRNA | CTD | PMID:17942748 | 17beta-estradiol | affects expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Estradiol affects the expression of MSRB2 mRNA | CTD | PMID:22574217 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Msrb2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MSRB2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MSRB2 mRNA | CTD | PMID:23152189 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Msrb2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MSRB2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Msrb2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MSRB2 mRNA | CTD | PMID:19770486 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MSRB2 mRNA more ... | CTD | PMID:28628672 | 4,4'-sulfonyldiphenol | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of MSRB2 mRNA | CTD | PMID:28628672 | 5-azacytidine | increases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Azacitidine results in increased expression of MSRB2 mRNA | CTD | PMID:19194470 | acetamide | decreases expression | EXP | | 6480464 | acetamide results in decreased expression of MSRB2 mRNA | CTD | PMID:31881176 | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of MSRB2 mRNA | CTD | PMID:28959563 | acrylamide | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Acrylamide results in decreased expression of MSRB2 mRNA | CTD | PMID:32763439 | all-trans-retinoic acid | increases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of MSRB2 mRNA | CTD | PMID:33167477 | antirheumatic drug | increases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of MSRB2 mRNA | CTD | PMID:24449571 | arsenous acid | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of MSRB2 mRNA | CTD | PMID:15725085 | arsenous acid | affects expression | ISO | Msrb2 (Mus musculus) | 6480464 | Arsenic Trioxide affects the expression of MSRB2 mRNA | CTD | PMID:31473893 | benzo[a]pyrene | increases expression | ISO | Msrb2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of MSRB2 mRNA | CTD | PMID:21715664 and PMID:22228805 | benzo[a]pyrene | increases methylation | ISO | Msrb2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased methylation of MSRB2 intron | CTD | PMID:27901495 | benzo[a]pyrene | decreases methylation | ISO | MSRB2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of MSRB2 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of MSRB2 mRNA | CTD | PMID:22316170 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MSRB2 mRNA | CTD | PMID:25181051 | bisphenol A | decreases methylation | ISO | MSRB2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of MSRB2 gene | CTD | PMID:31601247 | bisphenol A | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MSRB2 mRNA | CTD | PMID:28628672 | bisphenol A | affects methylation | ISO | Msrb2 (Mus musculus) | 6480464 | bisphenol A affects the methylation of MSRB2 promoter | CTD | PMID:27334623 | bisphenol A | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of MSRB2 mRNA | CTD | PMID:25912373 | bisphenol A | increases expression | ISO | Msrb2 (Mus musculus) | 6480464 | bisphenol A results in increased expression of MSRB2 mRNA | CTD | PMID:25594700 | bisphenol F | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of MSRB2 mRNA | CTD | PMID:28628672 | butanal | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of MSRB2 mRNA | CTD | PMID:26079696 | cadmium atom | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MSRB2 mRNA | CTD | PMID:35301059 | cadmium dichloride | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MSRB2 mRNA | CTD | PMID:35301059 | carbon nanotube | decreases expression | ISO | Msrb2 (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of MSRB2 mRNA | CTD | PMID:25554681 | CGP 52608 | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MSRB2 gene] | CTD | PMID:28238834 | cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of MSRB2 mRNA | CTD | PMID:20187946 | copper(II) sulfate | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of MSRB2 mRNA | CTD | PMID:19549813 | cyclosporin A | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of MSRB2 mRNA | CTD | PMID:20106945 | dexamethasone | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MSRB2 mRNA more ... | CTD | PMID:28628672 | diarsenic trioxide | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of MSRB2 mRNA | CTD | PMID:15725085 | diarsenic trioxide | affects expression | ISO | Msrb2 (Mus musculus) | 6480464 | Arsenic Trioxide affects the expression of MSRB2 mRNA | CTD | PMID:31473893 | diethylstilbestrol | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Diethylstilbestrol results in decreased expression of MSRB2 mRNA | CTD | PMID:36621641 | dioxygen | increases expression | EXP | | 6480464 | Oxygen deficiency results in increased expression of MSRB2 mRNA | CTD | PMID:22230185 | dioxygen | multiple interactions | ISO | Msrb2 (Mus musculus) | 6480464 | [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of MSRB2 mRNA | CTD | PMID:30529165 | dorsomorphin | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MSRB2 mRNA | CTD | PMID:27188386 | doxorubicin | decreases expression | ISO | Msrb2 (Mus musculus) | 6480464 | Doxorubicin results in decreased expression of MSRB2 mRNA | CTD | PMID:26873546 | doxorubicin | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of MSRB2 mRNA | CTD | PMID:29803840 | ethyl methanesulfonate | increases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in increased expression of MSRB2 mRNA | CTD | PMID:23649840 | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of MSRB2 mRNA | CTD | PMID:24136188 | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of MSRB2 mRNA | CTD | PMID:24136188 | folic acid | multiple interactions | ISO | Msrb2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MSRB2 mRNA | CTD | PMID:22206623 | indometacin | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of MSRB2 mRNA more ... | CTD | PMID:28628672 | inulin | multiple interactions | ISO | Msrb2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of MSRB2 mRNA | CTD | PMID:36331819 | L-1,4-dithiothreitol | increases reduction | ISO | MSRB2 (Homo sapiens) | 6480464 | Dithiothreitol results in increased reduction of MSRB2 protein | CTD | PMID:16735467 | menadione | affects expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Vitamin K 3 affects the expression of MSRB2 mRNA | CTD | PMID:20044591 | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of MSRB2 gene | CTD | PMID:35440735 | methylmercury chloride | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of MSRB2 mRNA | CTD | PMID:28001369 | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of MSRB2 mRNA | CTD | PMID:24136188 | nickel atom | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Nickel results in decreased expression of MSRB2 mRNA | CTD | PMID:25583101 | paracetamol | affects expression | ISO | Msrb2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MSRB2 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of MSRB2 mRNA | CTD | PMID:29067470 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Msrb2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MSRB2 mRNA more ... | CTD | PMID:36331819 | pirinixic acid | increases expression | ISO | Msrb2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of MSRB2 mRNA | CTD | PMID:18301758 and PMID:23811191 | SB 431542 | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MSRB2 mRNA | CTD | PMID:27188386 | silicon dioxide | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of MSRB2 mRNA | CTD | PMID:25895662 | sodium dodecyl sulfate | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in decreased expression of MSRB2 mRNA | CTD | PMID:31734321 | tert-butyl hydroperoxide | decreases response to substance | ISO | MSRB2 (Homo sapiens) | 6480464 | MSRB2 protein results in decreased susceptibility to tert-Butylhydroperoxide | CTD | PMID:15914630 | testosterone | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of MSRB2 mRNA | CTD | PMID:33359661 | tetrachloromethane | affects expression | ISO | Msrb2 (Mus musculus) | 6480464 | Carbon Tetrachloride affects the expression of MSRB2 mRNA | CTD | PMID:17484886 | tetrachloromethane | decreases expression | ISO | Msrb2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of MSRB2 mRNA | CTD | PMID:31919559 | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of MSRB2 mRNA | CTD | PMID:31150632 | thapsigargin | increases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Thapsigargin results in increased expression of MSRB2 mRNA | CTD | PMID:22378314 | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of MSRB2 mRNA | CTD | PMID:23411599 and PMID:34492290 | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of MSRB2 gene | CTD | PMID:27618143 | tunicamycin | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of MSRB2 mRNA | CTD | PMID:22378314 | urethane | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Urethane results in decreased expression of MSRB2 mRNA | CTD | PMID:28818685 | valproic acid | decreases expression | ISO | Msrb2 (Mus musculus) | 6480464 | Valproic Acid results in decreased expression of MSRB2 mRNA | CTD | PMID:21427059 | valproic acid | affects expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of MSRB2 mRNA | CTD | PMID:25979313 | valproic acid | decreases expression | ISO | MSRB2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MSRB2 mRNA | CTD | PMID:23179753 and PMID:26272509 | valproic acid | multiple interactions | ISO | MSRB2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of MSRB2 mRNA | CTD | PMID:27188386 | |