Uqcrh (ubiquinol-cytochrome c reductase hinge protein) - Rat Genome Database

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Gene: Uqcrh (ubiquinol-cytochrome c reductase hinge protein) Rattus norvegicus
Analyze
Symbol: Uqcrh
Name: ubiquinol-cytochrome c reductase hinge protein
RGD ID: 1305987
Description: Predicted to enable ubiquinol-cytochrome-c reductase activity. Predicted to be involved in mitochondrial electron transport, ubiquinol to cytochrome c. Part of mitochondrial respiratory chain complex III. Human ortholog(s) of this gene implicated in mitochondrial complex III deficiency. Orthologous to several human genes including UQCRH (ubiquinol-cytochrome c reductase hinge protein); PARTICIPATES IN electron transport chain pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: complex III subunit 6; complex III subunit VIII; cytochrome b-c1 complex subunit 6, mitochondrial; cytochrome c1 non-heme 11 kDa protein; LOC366448; MGC109658; mitochondrial hinge protein; ubiquinol-cytochrome c reductase complex 11 kDa protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,782,687 - 134,790,882 (-)NCBIGRCr8
mRatBN7.25129,545,978 - 129,554,173 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,545,984 - 129,554,242 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5132,162,175 - 132,170,197 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05133,917,061 - 133,925,081 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05133,939,196 - 133,947,216 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05134,919,040 - 134,927,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5134,919,044 - 134,927,235 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05138,702,773 - 138,710,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,255,481 - 136,263,676 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15136,260,706 - 136,268,898 (+)NCBI
Celera5128,076,102 - 128,084,160 (-)NCBICelera
Cytogenetic Map5q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methylcholine  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-fluorouracil  (ISO)
5-methyl-4-oxido-2-pyrazin-4-iumcarboxylic acid  (ISO)
acetamide  (EXP)
aldehydo-D-glucosamine  (ISO)
ampicillin  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenic trichloride  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
atrazine  (ISO)
beta-D-glucosamine  (ISO)
bilirubin IXalpha  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
chloropicrin  (ISO)
clofibric acid  (EXP)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
dieldrin  (EXP)
disulfiram  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenthion  (ISO)
flutamide  (ISO)
folic acid  (ISO)
gentamycin  (EXP)
heptachlor  (EXP)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
methapyrilene  (EXP)
methidathion  (ISO)
metronidazole  (EXP)
mitoxantrone  (ISO)
neomycin  (EXP)
ochratoxin A  (ISO)
paracetamol  (ISO)
PCB138  (ISO)
perfluorododecanoic acid  (EXP)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
selenium atom  (ISO)
sodium fluoride  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
tungsten  (ISO)
tunicamycin  (ISO)
vancomycin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Role of the hinge protein in the electron transfer between cardiac cytochrome c1 and c. Equilibrium constants and kinetic probes. Kim CH, etal., J Biol Chem. 1987 Jun 15;262(17):8103-8.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Mass spectrometric characterization of mitochondrial electron transport complexes: subunits of the rat heart ubiquinol-cytochrome c reductase. Sun G, etal., J Mass Spectrom 2003 May;38(5):531-9.
Additional References at PubMed
PMID:12477932   PMID:12865426   PMID:14651853   PMID:15489334   PMID:16120479   PMID:16854843   PMID:18614015   PMID:20833797   PMID:28844695   PMID:35352799  


Genomics

Comparative Map Data
Uqcrh
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,782,687 - 134,790,882 (-)NCBIGRCr8
mRatBN7.25129,545,978 - 129,554,173 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,545,984 - 129,554,242 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5132,162,175 - 132,170,197 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05133,917,061 - 133,925,081 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05133,939,196 - 133,947,216 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05134,919,040 - 134,927,235 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5134,919,044 - 134,927,235 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05138,702,773 - 138,710,968 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45136,255,481 - 136,263,676 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.15136,260,706 - 136,268,898 (+)NCBI
Celera5128,076,102 - 128,084,160 (-)NCBICelera
Cytogenetic Map5q35NCBI
UQCRH
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38146,303,698 - 46,316,776 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl146,303,698 - 46,316,776 (+)EnsemblGRCh38hg38GRCh38
GRCh37146,769,370 - 46,782,448 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36146,541,967 - 46,555,035 (+)NCBINCBI36Build 36hg18NCBI36
Build 34146,481,427 - 46,494,465NCBI
Celera145,056,760 - 45,069,814 (+)NCBICelera
Cytogenetic Map1p33NCBI
HuRef144,885,225 - 44,898,088 (+)NCBIHuRef
CHM1_1146,886,405 - 46,899,453 (+)NCBICHM1_1
T2T-CHM13v2.0146,180,920 - 46,193,993 (+)NCBIT2T-CHM13v2.0
Uqcrh
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394115,924,162 - 115,932,267 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4115,924,162 - 115,932,268 (-)EnsemblGRCm39 Ensembl
GRCm384116,066,965 - 116,075,070 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,066,965 - 116,075,071 (-)EnsemblGRCm38mm10GRCm38
MGSCv374115,739,570 - 115,747,675 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364115,564,897 - 115,572,980 (-)NCBIMGSCv36mm8
Celera4114,805,226 - 114,813,332 (-)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.1NCBI
LOC102022061
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495546411,963,706 - 11,975,959 (-)NCBIChiLan1.0ChiLan1.0
LOC100984974
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21180,491,655 - 180,504,541 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,633,240 - 179,646,124 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,606,924 - 45,619,811 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1146,961,538 - 46,975,055 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl146,961,538 - 46,975,055 (+)Ensemblpanpan1.1panPan2
UQCRH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,082,954 - 14,092,690 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,206,037 - 14,215,760 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01514,235,841 - 14,245,565 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,235,829 - 14,245,492 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,037,133 - 14,046,855 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,105,635 - 14,115,358 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,175,098 - 14,184,823 (-)NCBIUU_Cfam_GSD_1.0
UQCRH
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.16165,123,915 - 165,134,375 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26152,603,249 - 152,613,725 (-)NCBISscrofa10.2Sscrofa10.2susScr3
UQCRH
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12086,479,930 - 86,484,783 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603330,502,275 - 30,507,160 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
LOC101718708
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249062,217,180 - 2,226,075 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249062,217,142 - 2,226,075 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Uqcrh
33 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:28
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000016751
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5120740824143608494Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5124160767133749643Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5128033842133011550Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5129132428143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat

Markers in Region
RH129777  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25129,546,053 - 129,546,236 (+)MAPPERmRatBN7.2
Rnor_6.05134,919,116 - 134,919,298NCBIRnor6.0
Rnor_5.05138,702,849 - 138,703,031UniSTSRnor5.0
RGSC_v3.45136,263,418 - 136,263,600UniSTSRGSC3.4
Celera5128,076,178 - 128,076,360UniSTS
RH 3.4 Map5837.1UniSTS
Cytogenetic Map5q36UniSTS
BE108773  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25129,547,404 - 129,547,582 (+)MAPPERmRatBN7.2
Rnor_6.05134,920,467 - 134,920,644NCBIRnor6.0
Rnor_5.05138,704,200 - 138,704,377UniSTSRnor5.0
RGSC_v3.45136,262,072 - 136,262,249UniSTSRGSC3.4
Celera5128,077,470 - 128,077,647UniSTS
RH 3.4 Map5835.7UniSTS
Cytogenetic Map5q36UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 15
Medium 3 28 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001009480 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC086954 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217725 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223801 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223943 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000016751   ⟹   ENSRNOP00000016751
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5129,545,984 - 129,554,142 (-)Ensembl
Rnor_6.0 Ensembl5134,919,044 - 134,927,235 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111417   ⟹   ENSRNOP00000080974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5129,548,277 - 129,554,242 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000118108   ⟹   ENSRNOP00000085348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5129,546,039 - 129,554,242 (-)Ensembl
RefSeq Acc Id: NM_001009480   ⟹   NP_001009480
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85134,782,687 - 134,790,882 (-)NCBI
mRatBN7.25129,545,978 - 129,554,173 (-)NCBI
Rnor_6.05134,919,040 - 134,927,235 (-)NCBI
Rnor_5.05138,702,773 - 138,710,968 (-)NCBI
RGSC_v3.45136,255,481 - 136,263,676 (+)RGD
Celera5128,076,102 - 128,084,160 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001009480 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH86954 (Get FASTA)   NCBI Sequence Viewer  
  EDL90294 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000016751.5
  ENSRNOP00000080974.1
  ENSRNOP00000085348.1
GenBank Protein Q5M9I5 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001009480   ⟸   NM_001009480
- UniProtKB: Q5M9I5 (UniProtKB/Swiss-Prot),   A6JZ59 (UniProtKB/TrEMBL),   A0A8L2Q828 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000016751   ⟸   ENSRNOT00000016751
RefSeq Acc Id: ENSRNOP00000085348   ⟸   ENSRNOT00000118108
RefSeq Acc Id: ENSRNOP00000080974   ⟸   ENSRNOT00000111417
Protein Domains
Ubiquinol-cytochrome C reductase hinge

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5M9I5-F1-model_v2 AlphaFold Q5M9I5 1-89 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693926
Promoter ID:EPDNEW_R4451
Type:initiation region
Name:Uqcrh_1
Description:ubiquinol-cytochrome c reductase hinge protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05134,927,272 - 134,927,332EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1305987 AgrOrtholog
BioCyc Gene G2FUF-40267 BioCyc
BioCyc Pathway PWY-3781 [aerobic respiration I (cytochrome c)] BioCyc
  PWY-7279 [aerobic respiration II (cytochrome c) (yeast)] BioCyc
BioCyc Pathway Image PWY-3781 BioCyc
  PWY-7279 BioCyc
Ensembl Genes ENSRNOG00000012550 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000016751.7 UniProtKB/TrEMBL
  ENSRNOT00000111417.1 UniProtKB/TrEMBL
  ENSRNOT00000118108.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7368408 IMAGE-MGC_LOAD
InterPro Cyt_b-c1_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubol_cytC_Rdtase_hinge_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ubol_cytC_Rdtase_hinge_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:366448 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:109658 IMAGE-MGC_LOAD
NCBI Gene 366448 ENTREZGENE
PANTHER CYTOCHROME B-C1 COMPLEX SUBUNIT 6, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15336 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam UCR_hinge UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Uqcrh PhenoGen
PIRSF Bc1_11K UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012550 RatGTEx
Superfamily-SCOP SSF81531 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZU49_RAT UniProtKB/TrEMBL
  A0A8I6A162_RAT UniProtKB/TrEMBL
  A0A8L2Q828 ENTREZGENE, UniProtKB/TrEMBL
  A6JZ59 ENTREZGENE, UniProtKB/TrEMBL
  Q5M9I5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-12-06 Uqcrh  ubiquinol-cytochrome c reductase hinge protein  Uqcrh_predicted  ubiquinol-cytochrome c reductase hinge protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Uqcrh_predicted  ubiquinol-cytochrome c reductase hinge protein (predicted)      Symbol and Name status set to approved 70820 APPROVED