Dnajb4 (DnaJ heat shock protein family (Hsp40) member B4)

Gene: Dnajb4 (DnaJ heat shock protein family (Hsp40) member B4) Rattus norvegicus

Analyze

Symbol:

Dnajb4

Name:

DnaJ heat shock protein family (Hsp40) member B4

RGD ID:

1305826

Description:

Predicted to enable ATPase activator activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding and negative regulation of transcription by RNA polymerase II. Predicted to be located in Z disc; nucleoplasm; and plasma membrane. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in congenital myopathy 21. Orthologous to human DNAJB4 (DnaJ heat shock protein family (Hsp40) member B4); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

DnaJ (Hsp40) homolog, subfamily B, member 4; DnaJ (Hsp40) homolog, subfamily B, member 4-like; dnaJ homolog subfamily B member 4; LOC295549

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	243,790,296 - 243,819,042 (-)	NCBI		GRCr8
mRatBN7.2	2	241,129,346 - 241,159,272 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	241,130,340 - 241,159,089 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	248,944,119 - 248,972,815 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	246,831,137 - 246,859,833 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	241,730,451 - 241,759,204 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	257,394,692 - 257,425,344 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	257,394,818 - 257,425,242 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	276,071,439 - 276,102,091 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	250,663,022 - 250,685,242 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	233,065,020 - 233,093,753 (-)	NCBI		Celera
Cytogenetic Map	2	q45	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

congenital myopathy 21 (ISO)

distal myopathy (ISS)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-epigallocatechin 3-gallate (ISO)

(E)-cinnamyl alcohol (ISO)

1,2-dimethylhydrazine (ISO)

1,3-benzothiazole-2-thiol (ISO)

1,4-phenylenediamine (ISO)

1-chloro-2,4-dinitrobenzene (ISO)

1-fluoro-2,4-dinitrobenzene (ISO)

1-naphthyl isothiocyanate (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

2,5-hexanedione (EXP)

2,6-dinitrotoluene (EXP)

2-bromo-2-(bromomethyl)pentanedinitrile (ISO)

2-butoxyethanol (ISO)

2-Ethylhexyl acrylate (ISO)

2-hydroxyethyl methacrylate (ISO)

2-hydroxypropanoic acid (ISO)

3,3',4',5-tetrachlorosalicylanilide (ISO)

3-chloropropane-1,2-diol (EXP)

3-phenylprop-2-enal (ISO)

4,4'-diaminodiphenylmethane (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

4-hydroxynon-2-enal (ISO)

4-nitrobenzyl bromide (ISO)

abietic acid (ISO)

aconitine (EXP)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

antimonite (ISO)

Aroclor 1254 (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

Aurin (ISO)

azoxystrobin (ISO)

benzene (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bis(2-chloroethyl) sulfide (EXP)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Bisphenol A diglycidyl ether (ISO)

Bisphenol B (ISO)

cadmium atom (ISO)

cadmium dichloride (ISO)

cannabidiol (ISO)

carbamazepine (ISO)

carbaryl (ISO)

carbon nanotube (ISO)

celastrol (ISO)

chloropicrin (ISO)

chrysene (ISO)

cinnamyl alcohol (ISO)

cisplatin (ISO)

citral (ISO)

clofibrate (ISO)

clotrimazole (ISO)

cobalt atom (ISO)

cobalt dichloride (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) sulfate (ISO)

crotonaldehyde (ISO)

cyclophosphamide (ISO)

cyclosporin A (ISO)

diarsenic trioxide (ISO)

diazinon (ISO)

dibutyl phthalate (ISO)

diclofenac (ISO)

dicrotophos (ISO)

diethyl maleate (ISO)

dihydroxyacetone (ISO)

dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate (ISO)

dodecan-1-ol (ISO)

Dodecyl gallate (ISO)

elemental selenium (ISO)

elesclomol (ISO)

ethyl methanesulfonate (ISO)

eugenol (ISO)

farnesol (ISO)

fenofibrate (ISO)

formaldehyde (ISO)

FR900359 (ISO)

fulvestrant (ISO)

furan (ISO)

gamma-hexachlorocyclohexane (ISO)

gedunin (ISO)

genistein (ISO)

gentamycin (EXP)

geranial (ISO)

glyoxal (ISO)

isoeugenol (ISO)

ivermectin (ISO)

lead(0) (ISO)

lipopolysaccharide (ISO)

mercury dichloride (EXP)

methamphetamine (EXP)

methyl methanesulfonate (ISO)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

motexafin gadolinium (ISO)

N-acetyl-L-cysteine (ISO)

nickel dichloride (ISO)

ochratoxin A (ISO)

organoselenium compound (ISO)

ozone (EXP,ISO)

paracetamol (ISO)

PCB138 (EXP)

pentachlorophenol (ISO)

perfluorohexanesulfonic acid (ISO)

phenobarbital (ISO)

phlorizin (ISO)

pirinixic acid (ISO)

potassium chromate (ISO)

propiconazole (ISO)

quercetin (ISO)

rac-lactic acid (ISO)

raloxifene (ISO)

resorcinol (ISO)

resveratrol (ISO)

rotenone (ISO)

SCH 23390 (EXP)

selenium atom (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sodium dodecyl sulfate (ISO)

sulforaphane (ISO)

tamoxifen (ISO)

tert-butyl hydroperoxide (ISO)

tetrachloromethane (EXP,ISO)

tetraphene (ISO)

thalidomide (ISO)

thimerosal (ISO)

thiostrepton (ISO)

thiram (ISO)

titanium dioxide (ISO)

trans-isoeugenol (ISO)

triadimefon (ISO)

triptonide (ISO)

troglitazone (ISO)

Tungsten carbide (ISO)

undecanal (ISO)

urethane (ISO)

valproic acid (ISO)

vitamin E (ISO)

vorinostat (ISO)

zinc acetate (ISO)

zinc atom (ISO)

zinc pyrithione (ISO)

zinc(0) (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

chaperone cofactor-dependent protein refolding (IBA)

negative regulation of transcription by RNA polymerase II (IBA)

Cellular Component

cytosol (IBA,ISO)

nucleoplasm (IEA,ISO)

plasma membrane (IEA,ISO)

Z disc (ISO)

Molecular Function

ATPase activator activity (ISO)

protein binding (IPI,ISO)

protein-folding chaperone binding (IBA,ISO)

unfolded protein binding (IBA)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Mapping the in vitro interactome of cardiac sodium (Na+ )-calcium (Ca2+ ) exchanger 1 (NCX1).	Lubelwana Hafver T, etal., Proteomics. 2017 Sep;17(17-18). doi: 10.1002/pmic.201600417.
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:21231916	PMID:22871113	PMID:23376485	PMID:24318877

Genomics

Comparative Map Data

Dnajb4
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	243,790,296 - 243,819,042 (-)	NCBI		GRCr8
mRatBN7.2	2	241,129,346 - 241,159,272 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	241,130,340 - 241,159,089 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	248,944,119 - 248,972,815 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	246,831,137 - 246,859,833 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	241,730,451 - 241,759,204 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	257,394,692 - 257,425,344 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	257,394,818 - 257,425,242 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	276,071,439 - 276,102,091 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	250,663,022 - 250,685,242 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	2	233,065,020 - 233,093,753 (-)	NCBI		Celera
Cytogenetic Map	2	q45	NCBI

DNAJB4
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	77,979,175 - 78,017,964 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	77,979,175 - 78,017,964 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	78,444,859 - 78,483,648 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	78,243,224 - 78,255,586 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	78,182,656 - 78,195,014	NCBI
Celera	1	76,709,697 - 76,722,060 (+)	NCBI		Celera
Cytogenetic Map	1	p31.1	NCBI
HuRef	1	76,602,292 - 76,614,655 (+)	NCBI		HuRef
CHM1_1	1	78,587,021 - 78,599,380 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	77,817,970 - 77,856,789 (+)	NCBI		T2T-CHM13v2.0

Dnajb4
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	151,887,217 - 151,915,720 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	151,884,148 - 151,915,939 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	152,181,580 - 152,210,432 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	152,178,511 - 152,210,302 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	151,846,919 - 151,873,263 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	152,121,482 - 152,147,469 (-)	NCBI		MGSCv36	mm8
Celera	3	158,661,623 - 158,688,134 (-)	NCBI		Celera
Cytogenetic Map	3	H3	NCBI
cM Map	3	77.03	NCBI

Dnajb4
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955423	15,212,579 - 15,245,052 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955423	15,212,579 - 15,245,538 (-)	NCBI	ChiLan1.0	ChiLan1.0

DNAJB4
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	148,867,698 - 148,910,246 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	148,030,287 - 148,072,833 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	77,198,130 - 77,237,014 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	79,280,121 - 79,318,855 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	79,305,605 - 79,318,199 (+)	Ensembl	panpan1.1		panPan2

DNAJB4
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	68,878,823 - 68,923,306 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	68,879,690 - 68,888,810 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	71,536,300 - 71,581,141 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	69,463,848 - 69,508,504 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	69,463,850 - 69,507,967 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	68,971,033 - 69,015,441 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	68,915,350 - 68,959,992 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	69,402,186 - 69,446,409 (-)	NCBI		UU_Cfam_GSD_1.0

Dnajb4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	89,250,579 - 89,286,229 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936571	4,785,324 - 4,800,215 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936571	4,785,351 - 4,796,581 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DNAJB4
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	135,243,937 - 135,281,370 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	135,243,927 - 135,281,376 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	125,425,681 - 125,462,891 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DNAJB4
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	55,158,552 - 55,172,475 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	55,157,327 - 55,171,301 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666033	62,320,060 - 62,356,906 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dnajb4
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624742	19,249,122 - 19,260,502 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624742	19,249,122 - 19,279,504 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Dnajb4
91 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	73
Count of miRNA genes:	66
Interacting mature miRNAs:	70
Transcripts:	ENSRNOT00000017381
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	78665619	249053267	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	149559561	249053267	Rat
2317752	Glom23	Glomerulus QTL 23	3.6		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	2	193452645	245889826	Rat
1598835	Anxrr18	Anxiety related response QTL 18	2.98		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	2	200990457	245990457	Rat
7207490	Bss111	Bone structure and strength QTL 111	6.4		femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	2	211744537	249053267	Rat
7207482	Bss107	Bone structure and strength QTL 107	7		femur strength trait (VT:0010010)	femur ultimate force (CMO:0001675)	2	211744537	249053267	Rat
7207484	Bss108	Bone structure and strength QTL 108	5.3		femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	2	211744537	249053267	Rat
1298075	Scl17	Serum cholesterol level QTL 17	3.4		blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	2	211744537	249053267	Rat
1549836	Bss2	Bone structure and strength QTL 2	7.5		femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	2	211744537	249053267	Rat
2317885	Alcrsp28	Alcohol response QTL 28	2.1	0.63	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	212828222	249053267	Rat
1300126	Bp175	Blood pressure QTL 175	3.46		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	214226044	247136170	Rat
2293833	Kiddil8	Kidney dilation QTL 8	2.9		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	219753301	247136170	Rat
2293844	Kiddil7	Kidney dilation QTL 7	3.5		kidney pelvis morphology trait (VT:0004194)	hydronephrosis severity score (CMO:0001208)	2	219753301	247136170	Rat
9587428	Epfw6	Epididymal fat weight QTL 6	7.47	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	2	223389739	249053267	Rat
7411555	Bw132	Body weight QTL 132		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	2	223389739	249053267	Rat
631563	Hcuc3	Hepatic copper content QTL 3	3.87		liver copper amount (VT:0003065)	liver copper weight to liver dry weight ratio (CMO:0001512)	2	229059610	249053267	Rat

Markers in Region

BQ205681

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	241,130,437 - 241,130,612 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	257,395,845 - 257,396,019	NCBI	Rnor6.0
Rnor_5.0	2	276,072,592 - 276,072,766	UniSTS	Rnor5.0
RGSC_v3.4	2	250,684,969 - 250,685,143	UniSTS	RGSC3.4
Celera	2	233,065,119 - 233,065,293	UniSTS
RH 3.4 Map	2	1651.22	UniSTS
Cytogenetic Map	2	q45	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	47	31	19	31	8	11	74	35	41	11	8
Low			10	10		10
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001013076	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006233488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008761550	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC083638	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000017381 ⟹ ENSRNOP00000017381

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	241,130,340 - 241,159,089 (-)	Ensembl
Rnor_6.0 Ensembl	2	257,395,747 - 257,425,242 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000086878 ⟹ ENSRNOP00000075386

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	2	257,394,818 - 257,418,425 (-)	Ensembl

RefSeq Acc Id:

NM_001013076 ⟹ NP_001013094

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	243,790,296 - 243,819,042 (-)	NCBI
mRatBN7.2	2	241,130,339 - 241,159,089 (-)	NCBI
Rnor_6.0	2	257,395,746 - 257,425,242 (-)	NCBI
Rnor_5.0	2	276,071,439 - 276,102,091 (-)	NCBI
RGSC_v3.4	2	250,663,022 - 250,685,242 (+)	RGD
Celera	2	233,065,020 - 233,093,753 (-)	RGD

Sequence:

show sequence

GCCCAGCATGCTGCGGGGCGCTGAGCTGCCGCCGCCTGTGACCTCCAGCCCGGCCCGTCACAAG
CGGGGATGAACTCAGACCACCGGGCCCTTAGTTCTCGAGCTGATTACCTACCGAATCTATATGT
AAAATAATGTGGGCGAGCGGATGGTGAAAATATGACCTCCCTTTGTCCTTTAAAAACATAATTT
TCAAGCTGATTTGGGGTCATTTGAAGATGCACACCAGCTTCAAGTTGAAGGAGTAGGACTTTGC
ATCCTTTAAAAAAAGTATTCATTTCTGAGTCTGCACACACATGCCAGAGTGTGAAGACACCCTC
AGGATGGGCTCTTCCATGTCATTGTCGCACGCAGTGAGCTTTTAGGGAAATCTAAGTTCATTTC
AAGGCATTCGAAATGGGGAAAGACTATTATCACATTTTGGGAATTGAAAAAGGAGCTACAGATG
AAGATATTAAGAAGGCTTACCGAAAACAAGCCCTCAAATTTCATCCAGACAAGAACAAGTCTCC
TCAAGCAGAGGAAAAATTTAAAGAGGTCGCAGAAGCTTACGAAGTACTGAGTGATCCTAAAAAG
AGAGAAATATATGATCAGTTTGGCGAAGAAGGCCTGAAGGGTGGAGCTGGCGGCACTGACGGAC
AAGGAGGCACCTTCAGGTACACGTTCCACGGAGATCCGCATGCGACCTTTGCAGCCTTCTTTGG
AGGTGCCAACCCCTTTGAAATTTTCTTCGGGAGACGGATGGGTGGAGGCCGAGACTCTGAAGAG
ATGGAGATAGATGGCGACCCCTTCAGTGCCTTTGGCTTTAGCATGAATGGATATCCAAGAGACA
GGAATTCCGTGGGGCCCTCCCGTCTCAAGCAAGACCCTCCCATTATTCATGAACTCAAAGTCTC
GCTTGAAGAAATATACAGTGGCTGCACCAAACGGATGAAGATTTCTCGAAAGAGATTAAACCCT
GATGGAAGGAGTTACAGATCTGAGGATAAAATTCTCACCATTGAAATAAAGAAAGGGTGGAAAG
AAGGCACCAAAATTACTTTCCCAAGGGAAGGTGATGAAACACCAAATAGCATCCCAGCAGACAT
TGTTTTTATTATTAAAGACAAAGAACATCCCAAATTTAAGAGAGATGGATCGAATATAGTTTAT
ACTGCTAAAATTAGTTTACGGGAGGCATTGTGTGGCTGCTCAATTAATGTGCCAACAATGGATG
GAAGAAACATACCTATGTCAGTCACTGACATCGTGAAGCCTGGGATGAGGAGGAGAATTATTGG
CTATGGGCTGCCATTTCCAAAAAACCCAGACCAACGTGGCGACCTACTGATAGAATTTGATGTG
TCCTTCCCAGACGTCATTTCTGCAGCATCCAAAGAGATCCTTAGGAAACATCTCCCTGCCTCAT
AGAATGAGAAGAACCTTGCTATCCATATTTTGATAAGACACTGAAAATATAAAAGTACTGGCAG
TTTGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006233488 ⟹ XP_006233550

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	243,790,302 - 243,818,997 (-)	NCBI
mRatBN7.2	2	241,129,346 - 241,159,272 (-)	NCBI
Rnor_6.0	2	257,394,692 - 257,425,344 (-)	NCBI
Rnor_5.0	2	276,071,439 - 276,102,091 (-)	NCBI

Sequence:

show sequence

GGACGTCACGCAACAGTGTCCCGCGAGCGCGAGGCCGCAGAGCCCGAGGGCCTCGCGGGGCGTC
CGCGGCGAGGCTGCGGAACCGTCTGCCGCCCGGCGGGAGCCCAGCATGCTGCGGGGCGCTGAGC
TGCCGCCGCCTGTGACCTCCAGCCCGGCCCGTCACAAGCGGGGATGAACTCAGACCACCGGGCC
CTTAGTTCTCGAGCTGATTACCTACCGAATCTATATGTAAAATAATGTGGGCGAGCGGATGGTG
AAAATATGACCTCCCTTTGTCCTTTAAAAACTGTGAAGACACCCTCAGGATGGGCTCTTCCATG
TCATTGTCGCACGCAGTGAGCTTTTAGGGAAATCTAAGTTCATTTCAAGGCATTCGAAATGGGG
AAAGACTATTATCACATTTTGGGAATTGAAAAAGGAGCTACAGATGAAGATATTAAGAAGGCTT
ACCGAAAACAAGCCCTCAAATTTCATCCAGACAAGAACAAGTCTCCTCAAGCAGAGGAAAAATT
TAAAGAGGTCGCAGAAGCTTACGAAGTACTGAGTGATCCTAAAAAGAGAGAAATATATGATCAG
TTTGGCGAAGAAGGCCTGAAGGGTGGAGCTGGCGGCACTGACGGACAAGGAGGCACCTTCAGGT
ACACGTTCCACGGAGATCCGCATGCGACCTTTGCAGCCTTCTTTGGAGGTGCCAACCCCTTTGA
AATTTTCTTCGGGAGACGGATGGGTGGAGGCCGAGACTCTGAAGAGATGGAGATAGATGGCGAC
CCCTTCAGTGCCTTTGGCTTTAGCATGAATGGATATCCAAGAGACAGGAATTCCGTGGGGCCCT
CCCGTCTCAAGCAAGACCCTCCCATTATTCATGAACTCAAAGTCTCGCTTGAAGAAATATACAG
TGGCTGCACCAAACGGATGAAGATTTCTCGAAAGAGATTAAACCCTGATGGAAGGAGTTACAGA
TCTGAGGATAAAATTCTCACCATTGAAATAAAGAAAGGGTGGAAAGAAGGCACCAAAATTACTT
TCCCAAGGGAAGGTGATGAAACACCAAATAGCATCCCAGCAGACATTGTTTTTATTATTAAAGA
CAAAGAACATCCCAAATTTAAGAGAGATGGATCGAATATAGTTTATACTGCTAAAATTAGTTTA
CGGGAGGCATTGTGTGGCTGCTCAATTAATGTGCCAACAATGGATGGAAGAAACATACCTATGT
CAGTCACTGACATCGTGAAGCCTGGGATGAGGAGGAGAATTATTGGCTATGGGCTGCCATTTCC
AAAAAACCCAGACCAACGTGGCGACCTACTGATAGAATTTGATGTGTCCTTCCCAGACGTCATT
TCTGCAGCATCCAAAGAGATCCTTAGGAAACATCTCCCTGCCTCATAGAATGAGAAGAACCTTG
CTATCCATATTTTGATAAGACACTGAAAATATAAAAGTACTGGCAGTTTGACTGATGTGAATTC
TGTATAAAGATGTGTAGACTCTTCTGAGGGCTCATTAAATTGCATGAATAGAGACGGTTCAAAT
AGGCAAAAGTGGATTTTTACAGTAGAGATGAAGGTCATTCACTGTATTATATTTCATTTCTCCC
AAATCAGAAATTTTCAGTATTTCATTTATAAGTAAAAGTTGGTTTTGTGGTCTATAGATACACT
TCTAGTAAAGTACTAGATCATCCAAGTACACACTCTCTCTCTCTCTCTCTCTCTCTCTCTCTCT
CTCTCTCTCTTTCTCTGTGTGTGTGTGTGTGTGTGTGTATCTTTAAATGATCAGTGTGATAGGC
TGTCTTAATAGAAATTAAAATCCTTAACTGTATGTGACATATGTGGAGGAGAATAAAAGCCAAA
GTCATCAGAAATGCAGTCTGGGTCACATCCAGAACCGCTGTGTTGGGCTGGCACCAGAATGCAT
TGATGCTTTACTATTGTGACCTCTCAAGGATGCTGTAGCATTTTCTAAGAACATGGTTGTAATG
TTCCTAAACCAGACCTCCTCATAAGAAGAGAATGAATGACATTTTGTCTCCTGTGGACATCCCA
ATAGTCAGAGTTACTGGTATTTTAGAAACATTGTTTTGAAATGGCCACATGTAATTTTATGCAA
GTTGACTATATATCTTGAACTTAATAAGCTCATTTTGTGGTTCATTAGTTTAAGATATTTGTTT
ACTAATATTTGTTTTTAGAGAAAATACTGTTCCTTGGCATTAATTTCCCATTTGCAGTCTTCTG
TGAGCCCCTCATGCTGTATACCTTACATAATTTCCCTGAAGACACTGATCTACCATTACGACAT
TAAACCAAAATCTGAACACAATGGACAGCACCGCTGCTTGTGGGCGATGTTGTACTAGCTGTTA
CCGTATAAATATCTTACCTTTTCATGTATATAGATTGCATTTCTTAGGTGTTTTAATTTTTTAA
ATATATTTACATTTAAAAAATTACTGTCTTCTGTTTTATGTCTATCAAAAGTGATGTTATAAAA
ACTTTTTCTATAAAACA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001013094	(Get FASTA)	NCBI Sequence Viewer
	XP_006233550	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83638	(Get FASTA)	NCBI Sequence Viewer
	EDL82486	(Get FASTA)	NCBI Sequence Viewer
	EDL82487	(Get FASTA)	NCBI Sequence Viewer
	EDL82488	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000017381
	ENSRNOP00000017381.6

RefSeq Acc Id:

NP_001013094 ⟸ NM_001013076

- UniProtKB:

Q5XIP0 (UniProtKB/TrEMBL), F1LNN0 (UniProtKB/TrEMBL), A0A9K3Y755 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MGKDYYHILGIEKGATDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIY
DQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGANPFEIFFGRRMGGGRDSEEMEID
GDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPIIHELKVSLEEIYSGCTKRMKISRKRLNPDGRS
YRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKEHPKFKRDGSNIVYTAKI
SLREALCGCSINVPTMDGRNIPMSVTDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFDVSFPD
VISAASKEILRKHLPAS

hide sequence

RefSeq Acc Id:	XP_006233550 ⟸ XM_006233488
- Peptide Label:	isoform X1
- UniProtKB:	Q5XIP0 (UniProtKB/TrEMBL), F1LNN0 (UniProtKB/TrEMBL), A0A9K3Y755 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGKDYYHILGIEKGATDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIY DQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGANPFEIFFGRRMGGGRDSEEMEID GDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPIIHELKVSLEEIYSGCTKRMKISRKRLNPDGRS YRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKEHPKFKRDGSNIVYTAKI SLREALCGCSINVPTMDGRNIPMSVTDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFDVSFPD VISAASKEILRKHLPAS hide sequence

RefSeq Acc Id:

ENSRNOP00000017381 ⟸ ENSRNOT00000017381

RefSeq Acc Id:

ENSRNOP00000075386 ⟸ ENSRNOT00000086878

Protein Domains

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIP0-F1-model_v2	AlphaFold	Q5XIP0	1-337	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691823

Promoter ID:

EPDNEW_R2348

Type:

initiation region

Name:

Dnajb4_1

Description:

DnaJ heat shock protein family member B4

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	257,425,299 - 257,425,359	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305826	AgrOrtholog
BioCyc Gene	G2FUF-50807	BioCyc
Ensembl Genes	ENSRNOG00000013011	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000017381	ENTREZGENE
	ENSRNOT00000017381.7	UniProtKB/TrEMBL
Gene3D-CATH	1.10.287.110	UniProtKB/TrEMBL
	Urease metallochaperone UreE, N-terminal domain	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7134832	IMAGE-MGC_LOAD
InterPro	DnaJ_C	UniProtKB/TrEMBL
	DnaJ_dom_sf	UniProtKB/TrEMBL
	DnaJ_domain	UniProtKB/TrEMBL
	DnaJ_domain_CS	UniProtKB/TrEMBL
	HSP40/DnaJ_pept-bd	UniProtKB/TrEMBL
KEGG Report	rno:295549	UniProtKB/TrEMBL
MGC_CLONE	MGC:94459	IMAGE-MGC_LOAD
NCBI Gene	295549	ENTREZGENE
PANTHER	DNAJ HOMOLOG SUBFAMILY B MEMBER 4	UniProtKB/TrEMBL
	DNAJ HOMOLOG SUBFAMILY C MEMBER	UniProtKB/TrEMBL
Pfam	DnaJ	UniProtKB/TrEMBL
	DnaJ_C	UniProtKB/TrEMBL
PhenoGen	Dnajb4	PhenoGen
PRINTS	JDOMAIN	UniProtKB/TrEMBL
PROSITE	DNAJ_1	UniProtKB/TrEMBL
	DNAJ_2	UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000013011	RatGTEx
SMART	DnaJ	UniProtKB/TrEMBL
Superfamily-SCOP	DnaJ_N	UniProtKB/TrEMBL
	HSP40_DnaJ_pep	UniProtKB/TrEMBL
UniProt	A0A9K3Y755	ENTREZGENE, UniProtKB/TrEMBL
	F1LNN0	ENTREZGENE
	Q5XIP0	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	F1LNN0	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-25	Dnajb4	DnaJ heat shock protein family (Hsp40) member B4	Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2013-05-24	Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	LOC100359900	DnaJ (Hsp40) homolog, subfamily B, member 4-like	Data merged from RGD:2323144	1643240	APPROVED
2010-05-06	LOC100359900	DnaJ (Hsp40) homolog, subfamily B, member 4-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2005-12-06	Dnajb4	DnaJ (Hsp40) homolog, subfamily B, member 4	Dnajb4_predicted	DnaJ (Hsp40) homolog, subfamily B, member 4 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Dnajb4_predicted	DnaJ (Hsp40) homolog, subfamily B, member 4 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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