Gene: Pink1 (PTEN induced putative kinase 1) Rattus norvegicus
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Symbol: Pink1
Name: PTEN induced putative kinase 1
Description: ENCODES a protein that exhibits protein serine/threonine kinase activity; ubiquitin protein ligase binding; ATP binding (ortholog); INVOLVED IN cellular response to hydrogen sulfide; negative regulation of apoptotic process; negative regulation of gene expression; PARTICIPATES IN mitochondria dynamics pathway; altered mitochondrial autophagy pathway; mitochondrial autophagy pathway; ASSOCIATED WITH abnormal gait; abnormal motor coordination/ balance; abnormal muscle tone; ASSOCIATED WITH Parkinson Disease; Parkinson's disease; autosomal recessive early-onset Parkinson disease 6 (ortholog); FOUND IN growth cone; mitochondrial inner membrane; mitochondrial intermembrane space; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: LOC298575; MGC189438; serine/threonine-protein kinase PINK1, mitochondrial
Orthologs:
Homo sapiens (human) : PINK1 (PTEN induced putative kinase 1)  HGNC  AGR
Mus musculus (house mouse) : Pink1 (PTEN induced putative kinase 1)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Pink1 (PTEN induced putative kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : PINK1 (PTEN induced putative kinase 1)
Canis lupus familiaris (dog) : PINK1 (PTEN induced putative kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pink1 (PTEN induced putative kinase 1)
more info ...
Allele / Splice: Pink1em1Sage  
Genetic Models: LE-Pink1em1Sage-/- LE-Pink1em1Sage
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.05156,677,146 - 156,689,258 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.05160,425,715 - 160,437,827 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.45157,091,181 - 157,103,293 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.15157,100,712 - 157,113,336 (-)NCBI
Celera5148,924,018 - 148,936,130 (-)NCBI
Cytogenetic Map5q36NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on Pink1
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
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Vista + UCSC

RGD Object Information
RGD ID: 1305769
Created: 2005-01-12
Species: Rattus norvegicus
Last Modified: 2017-10-10
Status: ACTIVE